array:25 [
  "pii" => "S0870255116000135"
  "issn" => "08702551"
  "doi" => "10.1016/j.repc.2015.09.022"
  "estado" => "S300"
  "fechaPublicacion" => "2016-03-01"
  "aid" => "770"
  "copyright" => "Sociedade Portuguesa de Cardiologia"
  "copyrightAnyo" => "2016"
  "documento" => "article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "fla"
  "cita" => "Rev Port Cardiol. 2016;35:153-60"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2605
    "formatos" => array:3 [
      "EPUB" => 191
      "HTML" => 1803
      "PDF" => 611
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:20 [
      "pii" => "S2174204916000519"
      "issn" => "21742049"
      "doi" => "10.1016/j.repce.2015.09.015"
      "estado" => "S300"
      "fechaPublicacion" => "2016-03-01"
      "aid" => "770"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Rev Port Cardiol. 2016;35:153-60"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 2762
        "formatos" => array:3 [
          "EPUB" => 192
          "HTML" => 2045
          "PDF" => 525
        ]
      ]
      "en" => array:12 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
        "titulo" => "Gender differences in quality of life perception and cardiovascular risk in a community sample"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "tieneResumen" => array:2 [
          0 => "en"
          1 => "pt"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "153"
            "paginaFinal" => "160"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Diferen&#231;as de g&#233;nero na perce&#231;&#227;o de qualidade de vida e risco cardiovascular numa amostra comunit&#225;ria"
          ]
        ]
        "contieneResumen" => array:2 [
          "en" => true
          "pt" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Joana Prata, Amadeu Quelhas Martins, S&#243;nia Ramos, Francisco Rocha-Gon&#231;alves, Rui Coelho"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Joana"
                "apellidos" => "Prata"
              ]
              1 => array:2 [
                "nombre" => "Amadeu"
                "apellidos" => "Quelhas Martins"
              ]
              2 => array:2 [
                "nombre" => "S&#243;nia"
                "apellidos" => "Ramos"
              ]
              3 => array:2 [
                "nombre" => "Francisco"
                "apellidos" => "Rocha-Gon&#231;alves"
              ]
              4 => array:2 [
                "nombre" => "Rui"
                "apellidos" => "Coelho"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S0870255116000135"
          "doi" => "10.1016/j.repc.2015.09.022"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116000135?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204916000519?idApp=UINPBA00004E"
      "url" => "/21742049/0000003500000003/v1_201603180035/S2174204916000519/v1_201603180035/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S0870255116000408"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2015.11.008"
    "estado" => "S300"
    "fechaPublicacion" => "2016-03-01"
    "aid" => "782"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Cardiol. 2016;35:161-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3094
      "formatos" => array:3 [
        "EPUB" => 198
        "HTML" => 2298
        "PDF" => 598
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Time to left ventricular reverse remodeling after cardiac resynchronization therapy&#58; Better late than never"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "161"
          "paginaFinal" => "167"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Tempo para a remodelagem inversa do ventr&#237;culo esquerdo&#58; mais vale tarde do que nunca"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1158
              "Ancho" => 1518
              "Tamanyo" => 72999
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Clinical outcomes during follow-up&#46; LVRR&#58; left ventricular reverse remodeling&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Andr&#233; Viveiros Monteiro, M&#225;rio Martins Oliveira, Pedro Silva Cunha, Manuel Nogueira da Silva, Joana Feliciano, Lu&#237;sa Branco, Pedro Rio, Ricardo Pimenta, Ana Sofia Delgado, Rui Cruz Ferreira"
          "autores" => array:10 [
            0 => array:2 [
              "nombre" => "Andr&#233;"
              "apellidos" => "Viveiros Monteiro"
            ]
            1 => array:2 [
              "nombre" => "M&#225;rio"
              "apellidos" => "Martins Oliveira"
            ]
            2 => array:2 [
              "nombre" => "Pedro"
              "apellidos" => "Silva Cunha"
            ]
            3 => array:2 [
              "nombre" => "Manuel"
              "apellidos" => "Nogueira da Silva"
            ]
            4 => array:2 [
              "nombre" => "Joana"
              "apellidos" => "Feliciano"
            ]
            5 => array:2 [
              "nombre" => "Lu&#237;sa"
              "apellidos" => "Branco"
            ]
            6 => array:2 [
              "nombre" => "Pedro"
              "apellidos" => "Rio"
            ]
            7 => array:2 [
              "nombre" => "Ricardo"
              "apellidos" => "Pimenta"
            ]
            8 => array:2 [
              "nombre" => "Ana Sofia"
              "apellidos" => "Delgado"
            ]
            9 => array:2 [
              "nombre" => "Rui"
              "apellidos" => "Cruz Ferreira"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2174204916000520"
        "doi" => "10.1016/j.repce.2015.11.014"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204916000520?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116000408?idApp=UINPBA00004E"
    "url" => "/08702551/0000003500000003/v1_201603080050/S0870255116000408/v1_201603080050/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S0870255116000391"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2016.02.002"
    "estado" => "S300"
    "fechaPublicacion" => "2016-03-01"
    "aid" => "781"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "dis"
    "cita" => "Rev Port Cardiol. 2016;35:149-51"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4522
      "formatos" => array:3 [
        "EPUB" => 174
        "HTML" => 3641
        "PDF" => 707
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Coment&#225;rio editorial</span>"
      "titulo" => "Quanto importa a escolha do anticoagulante oral direto para a redu&#231;&#227;o da carga de acidente vascular cerebral na fibrilha&#231;&#227;o auricular&#63;"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "149"
          "paginaFinal" => "151"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "How much does the choice of new oral anticoagulant matter for reducing the burden of stroke in atrial fibrillation&#63;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Carlos Aguiar"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "Carlos"
              "apellidos" => "Aguiar"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2174204916000416"
        "doi" => "10.1016/j.repce.2016.02.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204916000416?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116000391?idApp=UINPBA00004E"
    "url" => "/08702551/0000003500000003/v1_201603080050/S0870255116000391/v1_201603080050/pt/main.assets"
  ]
  "en" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
    "titulo" => "Gender differences in quality of life perception and cardiovascular risk in a community sample"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "153"
        "paginaFinal" => "160"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Joana Prata, Amadeu Quelhas Martins, S&#243;nia Ramos, Francisco Rocha-Gon&#231;alves, Rui Coelho"
        "autores" => array:5 [
          0 => array:4 [
            "nombre" => "Joana"
            "apellidos" => "Prata"
            "email" => array:1 [
              0 => "joanappr&#64;gmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Amadeu"
            "apellidos" => "Quelhas Martins"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "S&#243;nia"
            "apellidos" => "Ramos"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Francisco"
            "apellidos" => "Rocha-Gon&#231;alves"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Rui"
            "apellidos" => "Coelho"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:4 [
          0 => array:3 [
            "entidad" => "Unidade de Investiga&#231;&#227;o &#38; Desenvolvimento Cardiovascular&#44; Faculdade de Medicina&#44; Universidade do Porto&#44; Porto&#44; Portugal"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Instituto Nacional de Engenharia Biom&#233;dica &#40;INEB&#41;&#44; Porto&#44; Portugal"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Instituto de Investiga&#231;&#227;o e Inova&#231;&#227;o em Sa&#250;de&#44; Universidade do Porto&#44; Porto&#44; Portugal"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Departamento de Neuroci&#234;ncias Cl&#237;nicas e Sa&#250;de Mental&#44; Faculdade de Medicina&#44; Universidade do Porto&#44; Porto&#44; Portugal"
            "etiqueta" => "d"
            "identificador" => "aff0020"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Diferen&#231;as de g&#233;nero na perce&#231;&#227;o de qualidade de vida e risco cardiovascular numa amostra comunit&#225;ria"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Cardiovascular disease &#40;CVD&#41; remains the leading cause of premature death in Europe&#46; Unhealthy lifestyles and psychosocial burden are commonly associated with CVD&#44; and not surprisingly&#44; most of its mortality is preventable through appropriate changes in lifestyle&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">1</span></a> It is well established that psychosocial risk factors interact with biomedical vulnerabilities in the development of CVD&#44; and approximately one third of the attributable risk of acute myocardial infarction can be related to major life events&#44; depression or stress related to work&#44; family or finances&#46; Furthermore&#44; when several psychosocial risk factors cluster in the same individual&#44; the risk for both cardiac events and severe atherosclerosis is substantially increased&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Men and women have similar biomedical risk factors for CVD&#44; but their relative weight and impact on the pathophysiology of the disease differ markedly&#46;<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">3</span></a> Prevention strategies could benefit from taking these risk profile differences into account&#46; Further&#44; gender differences in both disease progression and impact of risk factors could explain why prevalence rates&#44; symptom profiles and medical outcomes still have different prevalences between genders&#46;<a class="elsevierStyleCrossRefs" href="#bib0220"><span class="elsevierStyleSup">4&#44;5</span></a> Specifically&#44; women with ischemic heart disease have worse outcomes than men regardless of age&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">4</span></a> but usually present much less severe anatomical obstructive lesions and better preserved systolic function&#46;<a class="elsevierStyleCrossRefs" href="#bib0220"><span class="elsevierStyleSup">4&#44;6</span></a> Clearly&#44; other factors are at play in this apparent contradiction&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">It is well established that psychosocial factors such as negative affect and personality traits can increase the risk for CVD&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">2</span></a> However&#44; it is unknown whether they also impact cardiovascular health differentially by gender&#44; thereby contributing to higher CVD morbidity and mortality among women&#46; Specifically&#44; depression is an established risk factor for both CVD patients and healthy individuals&#44; increasing both cardiac morbidity and mortality&#44;<a class="elsevierStyleCrossRefs" href="#bib0235"><span class="elsevierStyleSup">7&#8211;9</span></a> while anxiety has been identified as an independent risk factor for CVD in the community&#46;<a class="elsevierStyleCrossRefs" href="#bib0250"><span class="elsevierStyleSup">10&#44;11</span></a> Similarly&#44; type D personality is a stable personality construct marked by negative affectivity and social inhibition that combine to produce sustained high levels of mental distress and increased physical symptoms in both CVD patients and healthy participants&#46;<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">12&#8211;14</span></a> Overall&#44; these psychosocial factors have been consistently linked to CVD risk&#44; but little progress has been made in examining their differential impact by gender&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Self-reported health is an independent predictor of overall and cardiovascular mortality in most studies&#44; and individuals who assess their health as fair or poor have a higher mortality risk than those whose assessment is better&#46;<a class="elsevierStyleCrossRefs" href="#bib0275"><span class="elsevierStyleSup">15&#44;16</span></a> Moreover&#44; after controlling for sociodemographic characteristics&#44; health care access and risk factors&#44; self-reported health is still a significant and independent predictor of both global morbidity onset<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">15</span></a> and CVD incidence&#46;<a class="elsevierStyleCrossRefs" href="#bib0285"><span class="elsevierStyleSup">17&#44;18</span></a> Specifically&#44; the Medical Outcomes Study Short Form &#40;SF-36&#41; has been shown to predict mortality in community samples&#46;<a class="elsevierStyleCrossRefs" href="#bib0295"><span class="elsevierStyleSup">19&#44;20</span></a> In particular&#44; the physical component summary of the SF-36 &#40;derived from the sum of scores obtained on the physical functioning&#44; role-physical&#44; bodily pain and general health subscales&#41; exhibits a strong association with mortality&#44; estimates being independent of other physical factors like obesity&#44; physical inactivity or a low-fiber diet&#46;<a class="elsevierStyleCrossRefs" href="#bib0295"><span class="elsevierStyleSup">19&#44;20</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">This study aimed to assess how gender patterns of known cardiovascular risk factors &#40;biomedical and psychosocial&#41; influence self-reported quality of life in a sample of primary health care users without a CVD diagnosis&#46; To the best our knowledge&#44; this study is pioneering in bridging these two important issues&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Participants</span><p id="par0030" class="elsevierStylePara elsevierViewall">As part of a prospective study&#44; 261 primary health care users &#40;158 women&#41; were recruited in various health provision settings in the northern region of Portugal&#46; The study design was explained to each participant and written informed consent was obtained&#46; Exclusion criteria comprised either documented or self-reported CVD&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Instruments</span><p id="par0035" class="elsevierStylePara elsevierViewall">Participants were interviewed and assessed for various demographic&#44; behavioral&#44; clinical and psychosocial measures&#46; Questionnaires were used to collect these data&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The Hospital Anxiety and Depression Scale &#40;HADS&#41; is a self-evaluation questionnaire which comprises two subscales&#44; one measuring depression &#40;HAD-D&#41; and the other measuring anxiety &#40;HAD-A&#41;&#46;<a class="elsevierStyleCrossRefs" href="#bib0305"><span class="elsevierStyleSup">21&#44;22</span></a> The HADS has been validated for the Portuguese population&#46;<a class="elsevierStyleCrossRef" href="#bib0315"><span class="elsevierStyleSup">23</span></a> A HADS cutoff score greater than 7 in any of the subscales indicates the presence of symptoms&#44; e&#46;g&#46; HAD-D &#8805;8 indicates depressive symptoms&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Type D personality was assessed using a Portuguese version of the Type D Scale-14 &#40;DS14&#41;&#44; which comprises 14 items&#44; seven assessing negative affectivity and seven assessing social inhibition&#46;<a class="elsevierStyleCrossRef" href="#bib0320"><span class="elsevierStyleSup">24</span></a> A score of at least 10 on both subscales identifies individuals as having type D &#40;or distressed&#41; personality&#46;<a class="elsevierStyleCrossRef" href="#bib0325"><span class="elsevierStyleSup">25</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Quality of life was assessed using the Portuguese version of the Medical Outcomes Study Short Form SF-36&#44;<a class="elsevierStyleCrossRefs" href="#bib0330"><span class="elsevierStyleSup">26&#44;27</span></a> which comprises 36 questions across eight subscales of functional health and well-being&#58; physical functioning&#44; role-physical&#44; bodily pain&#44; general health&#44; mental health&#44; role-emotional&#44; social functioning and vitality&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Data reduction and analysis</span><p id="par0055" class="elsevierStylePara elsevierViewall">Univariate analysis was used to compare demographic&#44; behavioral&#44; clinical and psychometric variables between genders&#46; Differences between proportions were examined with chi-square tests&#44; while mean comparisons were conducted with Student&#39;s t tests&#46; A multivariate logistic regression analysis &#40;backward stepwise method&#41; was conducted to quantify independent associations of previously identified correlates with gender&#46; Adjusted odds ratios &#40;OR&#41; with 95&#37; confidence intervals are reported&#46; A series of multivariate linear regression analyses were conducted separately by gender to identify putative predictors of quality of life scores&#46; The statistical significance level was set at p&#60;0&#46;05&#46;</p></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Results</span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Univariate analysis</span><p id="par0060" class="elsevierStylePara elsevierViewall">Sociodemographic and clinical variables were compared by gender &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46; No differences were found regarding age&#44; educational level&#44; living status or occupation&#46; Women presented significantly lower alcohol consumption &#40;p&#60;0&#46;001&#41;&#44; lower body mass index &#40;p&#60;0&#46;001&#41; and less exercise activity &#40;p&#60;0&#46;05&#41; than men&#46; Regarding psychosocial measures &#40;<a class="elsevierStyleCrossRef" href="#tbl0020">Table 2</a>&#41;&#44; women scored significantly higher than men for HAD-D &#40;p&#60;0&#46;05&#41;&#44; which was corroborated by a greater proportion of women &#40;19&#37; vs&#46; 9&#46;7&#37;&#41; exceeding the scale cutoff for depression &#40;p&#60;0&#46;05&#41;&#46; A history of antidepressant medication use &#40;p&#61;0&#46;05&#41; and psychiatric referral and&#47;or complaints &#40;p&#60;0&#46;05&#41; was also more common among women&#46; The prevalence of type D personality was similar between genders&#44; although women scored significantly higher than men in negative affectivity &#40;p&#61;0&#46;05&#41;&#46; Finally&#44; women had lower scores in all SF-36 dimensions&#44; indicating an overall perception of poorer health and well-being&#44; and this was statistically significant for all dimensions with the exception of general health &#40;p&#61;0&#46;505&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0020"></elsevierMultimedia></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Multivariate analysis</span><p id="par0065" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0035">Table 3</a> shows the multivariate logistic regression model &#40;Nagelkerke R<span class="elsevierStyleSup">2</span>&#61;0&#46;32&#41; obtained for the independent correlates of gender&#46; Lower body mass index &#40;p&#60;0&#46;001&#41;&#44; less frequent exercise &#40;p&#60;0&#46;01&#41;&#44; and less alcohol consumption &#40;p&#60;0&#46;001&#41; were all independently associated with women &#40;<a class="elsevierStyleCrossRef" href="#tbl0035">Table 3</a>&#41;&#46; Further&#44; women were more than twice as likely than men to use antidepressants &#40;OR 2&#46;877&#44; p&#61;0&#46;05&#41; and to exceed the HADS-D cutoff for depression &#40;OR 2&#46;137&#44; p&#61;0&#46;098&#41;&#46;</p><elsevierMultimedia ident="tbl0035"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0060">Table 4</a> displays the results of the multivariate linear regression analysis of participants&#8217; quality of life scores &#40;only statistically significant scores are shown&#41;&#46; Among men&#44; an increased sense of &#8216;physical functioning&#8217; was predicted by lower body mass&#44; more frequent exercise&#44; less prevalent chronic illness and less antidepressant use&#44; alongside a lower score for social inhibition &#40;DS14&#41;&#46; In women&#44; living alone&#44; higher education and more exercise predicted better &#8216;physical functioning&#8217;&#44; while higher prevalences of hypertension&#44; diabetes and antidepressant use were related to worse &#8216;physical functioning&#8217;&#46; Role limitations due to physical problems &#40;&#8216;role-physical&#8217; subscale&#44; on which higher scores indicate less limitation due to physical problems&#41; were mainly associated with the prevalence of diabetes in men&#46; In women&#44; higher body mass&#44; higher depression scores &#40;HADS-D&#41; and more antidepressant use predicted more role limitations due to physical problems&#46; Not surprisingly&#44; a higher prevalence of hypertension and other chronic illness was predictive of more pain complaints in men &#40;&#8216;bodily pain&#8217; subscale&#44; on which higher scores indicate less pain complaints&#41;&#44; whereas more frequent exercise was predictive of less pain complaints&#46; In women&#44; more pain complaints were predicted by higher body mass&#44; higher prevalences of diabetes and psychiatric referrals&#44; and higher DS14 scores for negative affectivity&#46; In men&#44; better &#8216;general health&#8217; was predicted by younger age&#44; a lower prevalence of diabetes&#44; and lower anxiety &#40;HADS-A&#41; and social inhibition &#40;DS14&#41; scores&#44; while better &#8216;mental health&#8217; was solely predicted by lower scores on the anxiety &#40;HADS-A&#41;&#44; depression &#40;HADS-D&#41; and negative affectivity &#40;DS14&#41; scales&#46; In women&#44; however&#44; better &#8216;general health&#8217; was predicted by lower body mass&#44; less prevalence of diabetes and other chronic illness&#44; and lower negative affectivity scores &#40;DS14&#41;&#46; Similarly to men&#44; women reporting better &#8216;mental health&#8217; were those with lower anxiety &#40;HADS-A&#41;&#44; depression &#40;HADS-D&#41; and negative affectivity &#40;DS14&#41; scores&#46; Lower depression scores &#40;HADS-D&#41; predicted less role limitations due to emotional problems &#40;a higher score on the &#8216;role-emotional&#8217; dimension&#41;&#44; while better &#8216;social functioning&#8217; was associated with lower HADS-A scores in anxiety in men&#46; In women&#44; less role limitations due to emotional problems &#40;a higher score on the &#8216;role-emotional&#8217; dimension&#41; were predicted by less alcohol consumption&#44; and lower depression &#40;HADS-D&#41; and negative affectivity &#40;DS14&#41; scores&#46; Concomitantly&#44; better &#8216;social functioning&#8217; was also predicted by less alcohol consumption and lower anxiety &#40;HADS-A&#41;&#44; depression &#40;HADS-D&#41; and social inhibition &#40;DS14&#41; scores&#46; Finally&#44; men with lower educational level and lower scores on the anxiety &#40;HADS-A&#41;&#44; depression &#40;HADS-D&#41; and social inhibition &#40;DS14&#41; scales had a greater sense of &#8216;vitality&#8217;&#46; In women&#44; greater vitality was significantly predicted by lower depression &#40;HADS-D&#41; and negative affectivity &#40;DS14&#41; scores&#46;</p><elsevierMultimedia ident="tbl0060"></elsevierMultimedia></span></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Discussion</span><p id="par0075" class="elsevierStylePara elsevierViewall">This study sought to examine how gender patterns of cardiovascular risk factors associate with self-reported quality of life in a sample of primary health care users without a CVD diagnosis&#46; Our main findings pinpointed gender differences in risk factors mostly related to participants&#8217; life style and mental&#47;affective status&#46; Specifically&#44; women revealed significantly lower rates of alcohol consumption and exercise but presented more depressive symptoms and negative affectivity&#46; In agreement with these findings&#44; a history of antidepressant use and psychiatric referrals was also more common among women&#46; Further&#44; our multivariate analysis expanded these findings to confirm most of these risk factors as independent correlates for females&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Interestingly&#44; traditional biomedical CVD risk factors&#44; such as smoking&#44; hypertension&#44; diabetes and dyslipidemia&#44; did not differ between genders&#46; This finding partially supports the hypothesis of a different pathophysiological impact of CVD risk for female gender&#44; possibly through the deleterious action of psychosocial risk factors like those mentioned above&#46; In line with this suggestion&#44; the quality of life assessment for female participants indicated overall poorer health and well-being&#44; despite the absence of any objective gender difference in biomedical risk factors&#44; which is in agreement with other studies that also reported lower quality of life scores for women&#46;<a class="elsevierStyleCrossRef" href="#bib0340"><span class="elsevierStyleSup">28</span></a></p><p id="par0085" class="elsevierStylePara elsevierViewall">It is still not fully understood how educational level can influence the risk for CVD&#46; Several studies have examined this and suggest that education partially affects this risk through increased prevalence of CVD risk factors at lower educational levels&#46;<a class="elsevierStyleCrossRef" href="#bib0345"><span class="elsevierStyleSup">29</span></a> In our study&#44; despite the high educational level of the participants&#44; we found a relatively high prevalence of risk factors which are mostly lifestyle dependent&#46; We cannot exclude the possibility that our high educational level sampling masked any latent differences in traditional CVD risk factors&#46; However&#44; 36&#46;1&#37; of the women in our study did not exercise at all&#44; which is higher than expected as studies have shown that lower education or occupation levels are usually associated with a higher prevalence of sedentariness among women&#46;<a class="elsevierStyleCrossRef" href="#bib0350"><span class="elsevierStyleSup">30</span></a> Also&#44; no gender differences were found in smoking patterns&#44; with the majority of participants being non-smokers&#46; This follows the trend of western populations&#44; where the prevalence of smoking is declining for both genders and increasing in lower social classes&#46;<a class="elsevierStyleCrossRef" href="#bib0355"><span class="elsevierStyleSup">31</span></a></p><p id="par0090" class="elsevierStylePara elsevierViewall">Women had a prevalence of depressive symptoms that was more than twice that reported by men&#46; In addition&#44; psychiatric referrals and antidepressant use were also more prevalent among women&#46; These data are in line with previous evidence showing that women are about twice as likely as men to experience depression&#46;<a class="elsevierStyleCrossRef" href="#bib0360"><span class="elsevierStyleSup">32</span></a> In addition&#44; 22&#46;3&#37; of men and 25&#46;9&#37; of women were classified as anxious according to the HADS-A&#46; This finding is apparently at odds with studies indicating a protective effect of educational level against anxiety and depression&#44;<a class="elsevierStyleCrossRef" href="#bib0365"><span class="elsevierStyleSup">33</span></a> but it might derive from an overall young sample&#46; Finally&#44; the prevalence of type D personality was similar between genders&#44; replicating previous research&#46;<a class="elsevierStyleCrossRefs" href="#bib0370"><span class="elsevierStyleSup">34&#44;35</span></a> Nevertheless&#44; women did score significantly higher than men on the negative affectivity subscale of the DS14&#44; which has been considered elsewhere as a key predictor of worse subjective health outcomes&#46;<a class="elsevierStyleCrossRef" href="#bib0380"><span class="elsevierStyleSup">36</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">This study examined how gender patterns in CVD risk influence self-reported health and quality of life perception&#46; Women reported significantly worse levels of well-being and health across most subscales of the SF-36 questionnaire&#44; with the exception of the general health subscale &#40;for which scores did not reach statistical significance&#44; although they were still lower&#41;&#46; Based on the findings of others&#44;<a class="elsevierStyleCrossRefs" href="#bib0275"><span class="elsevierStyleSup">15&#44;17&#44;18</span></a> this could indicate that&#44; in this study&#44; women faced a higher risk for cardiovascular morbidity and mortality&#46; Firstly&#44; recent evidence indicates that poor self-rated health is strongly associated with cardiovascular mortality&#44; irrespective of prior CVD&#44;<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">16</span></a> and with the incidence of coronary heart disease&#46;<a class="elsevierStyleCrossRefs" href="#bib0285"><span class="elsevierStyleSup">17&#44;18</span></a> Secondly&#44; the physical health component of the SF-36 has been specifically identified as a strong predictor of CVD incidence and death in post-menopausal women&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">20</span></a> Thirdly&#44; although the mechanisms underlying this association remain speculative&#44; the fact is that the SF-36 physical health component exhibits a strong association with mortality&#44; while this effect is independent of other risk factors like obesity&#44; physical inactivity or diet&#46;<a class="elsevierStyleCrossRefs" href="#bib0295"><span class="elsevierStyleSup">19&#44;20</span></a></p><p id="par0100" class="elsevierStylePara elsevierViewall">Among the gender distinctiveness apparent in the multivariate linear regression profiles of the quality of life scores&#44; role limitations due to physical problems &#40;&#8216;role-physical&#8217;&#41; and more pain complaints &#40;&#8216;bodily pain&#8217;&#41; were predicted by psychosocial risk factors such as depression and negative affectivity in women&#44; whereas in men these two dimensions appear to depend more on biomedical factors such as diabetes&#44; hypertension&#44; exercise and chronic illness&#46; A recent study with healthy participants found that type D personality was significantly associated with lower quality of life and more physical symptoms&#44; with the negative affectivity component standing out as the key predictor of subjective health outcomes&#46;<a class="elsevierStyleCrossRef" href="#bib0380"><span class="elsevierStyleSup">36</span></a> In our study&#44; high negative affectivity was a strong independent predictor of worse general health for women&#44; whereas high social inhibition and high anxiety had a comparable role for men&#46; These results are worth highlighting given the predictive value of the SF-36 physical health component for CVD mortality and morbidity&#46; Indeed&#44; this distinct gender pattern may be the key to the differential impact of psychosocial risk factors on CVD risk&#44; and should therefore be examined&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">This study involves a population with highly specific characteristics&#44; which is relevant for the following reasons&#46; Firstly&#44; our participants were relatively young and had a high educational level&#46; While this requires caution regarding the generalization of findings to other populations&#44; the fact is that studies aiming to enhance CVD prevention tend to be conducted with increasingly young samples&#46;<a class="elsevierStyleCrossRefs" href="#bib0385"><span class="elsevierStyleSup">37&#44;38</span></a> Secondly&#44; our investigation followed an observational cross-sectional design&#44; which precludes any generalization concerning longitudinal trends of the associations found&#46; Thirdly&#44; most of the data collection relied on self-reporting&#44; hence reflecting the individual&#39;s assessment of currently experienced symptoms&#46; Although memory bias could have distorted the data&#44; such an effect is likely to be reflected similarly within the whole sample&#46; Finally&#44; multivariate analyses of quality of life scores were conducted separately by gender&#46; On the one hand&#44; sample size was limited in order to run meaningful multivariate linear regression comparisons between genders&#46; On the other hand&#44; the available evidence regarding self-rated health by gender is still inconsistent&#44; with studies indicating no differences&#44;<a class="elsevierStyleCrossRef" href="#bib0395"><span class="elsevierStyleSup">39</span></a> a tendency for men to assess their health more positively than women&#44;<a class="elsevierStyleCrossRef" href="#bib0340"><span class="elsevierStyleSup">28</span></a> or even the opposite&#46;<a class="elsevierStyleCrossRef" href="#bib0400"><span class="elsevierStyleSup">40</span></a></p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Conclusions and implications for practice</span><p id="par0110" class="elsevierStylePara elsevierViewall">This study shows that community participants without documented CVD present gender-specific patterns of CVD risk factors and that these impact quality of life differentially&#46; In our view&#44; these gender specifics need to be considered in health prevention strategies&#44; given the predictive value of quality of life for cardiovascular morbidity and mortality&#46;</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Ethical disclosures</span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Protection of human and animal subjects</span><p id="par0115" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Confidentiality of data</span><p id="par0120" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">Right to privacy and informed consent</span><p id="par0125" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">Conflicts of interest and funding</span><p id="par0130" class="elsevierStylePara elsevierViewall">The lead author received funding from Funda&#231;&#227;o para a Ci&#234;ncia e a Tecnologia in the form of a PhD grant &#40;SFRH&#47;BD&#47;70327&#47;2010&#41;&#46; The other authors have no conflicts of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:12 [
        0 => array:3 [
          "identificador" => "xres613028"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Introduction"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Methods"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusion"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec626811"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres613027"
          "titulo" => "Resumo"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Introdu&#231;&#227;o"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "M&#233;todos"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclus&#245;es"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec626812"
          "titulo" => "Palavras-chave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:3 [
          "identificador" => "sec0010"
          "titulo" => "Methods"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Participants"
            ]
            1 => array:2 [
              "identificador" => "sec0020"
              "titulo" => "Instruments"
            ]
            2 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Data reduction and analysis"
            ]
          ]
        ]
        6 => array:3 [
          "identificador" => "sec0030"
          "titulo" => "Results"
          "secciones" => array:2 [
            0 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Univariate analysis"
            ]
            1 => array:2 [
              "identificador" => "sec0040"
              "titulo" => "Multivariate analysis"
            ]
          ]
        ]
        7 => array:2 [
          "identificador" => "sec0045"
          "titulo" => "Discussion"
        ]
        8 => array:2 [
          "identificador" => "sec0050"
          "titulo" => "Conclusions and implications for practice"
        ]
        9 => array:3 [
          "identificador" => "sec0055"
          "titulo" => "Ethical disclosures"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0060"
              "titulo" => "Protection of human and animal subjects"
            ]
            1 => array:2 [
              "identificador" => "sec0065"
              "titulo" => "Confidentiality of data"
            ]
            2 => array:2 [
              "identificador" => "sec0070"
              "titulo" => "Right to privacy and informed consent"
            ]
          ]
        ]
        10 => array:2 [
          "identificador" => "sec0075"
          "titulo" => "Conflicts of interest and funding"
        ]
        11 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2015-06-09"
    "fechaAceptado" => "2015-09-13"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec626811"
          "palabras" => array:4 [
            0 => "Cardiovascular risk factors"
            1 => "Self-reported health"
            2 => "Quality of life"
            3 => "Gender"
          ]
        ]
      ]
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec626812"
          "palabras" => array:4 [
            0 => "Fatores de risco cardiovascular"
            1 => "Sa&#250;de auto-relatada"
            2 => "Qualidade de vida"
            3 => "Especificidades de g&#233;nero"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Self-reported heath and quality of life is an independent predictor of overall and cardiovascular morbidity and mortality&#44; and incident coronary heart disease&#46; However&#44; less is known regarding how gender differences in cardiovascular risk factors impact quality of life perception&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Primary healthcare users &#40;n&#61;261&#44; 158 women&#41; were screened for cardiovascular risk factors and completed the Medical Outcomes Study Short Form &#40;SF-36&#41;&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Women had significantly lower alcohol consumption&#44; body mass index and exercise frequency than men&#44; but more prevalent psychiatric history&#44; depressive and anxiety symptoms&#44; and negative affectivity&#46; Prevalences of hypertension&#44; diabetes&#44; dyslipidemia and type D personality were similar between genders&#46; Women reported significantly worse quality of life on most SF-36 subscales and gender differences were apparent in predictors of quality of life&#46; Moreover&#44; high negative affectivity was an independent predictor of worse general health for women&#44; whereas high social inhibition and high anxiety had a comparable role for men&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Gender specifics in cardiovascular risk factors should be considered in prevention strategies&#46; Women reported significantly worse quality of life&#44; putting them at higher risk for cardiovascular morbidity and mortality&#46; Therefore&#44; gender differences in predictors of quality of life warrant further investigation&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introduction"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Methods"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusion"
          ]
        ]
      ]
      "pt" => array:3 [
        "titulo" => "Resumo"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introdu&#231;&#227;o</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">A perce&#231;&#227;o de qualidade de vida &#233; um preditor independente de mortalidade geral&#44; morbilidade e mortalidade cardiovascular&#44; e incid&#234;ncia de doen&#231;a card&#237;aca coron&#225;ria&#46; Contudo&#44; permanece por esclarecer qual o impacto que as diferen&#231;as espec&#237;ficas de g&#233;nero nos fatores de risco cardiovascular t&#234;m na perce&#231;&#227;o de qualidade de vida&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Duzentos e sessenta e um utentes dos cuidados prim&#225;rios &#40;158 mulheres&#41; foram rastreados para fatores de risco cardiovascular e preencheram a vers&#227;o portuguesa do <span class="elsevierStyleItalic">Medical Outcomes Study Short Form</span> &#40;SF-36&#41;&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">As mulheres apresentaram um padr&#227;o de menor consumo de &#225;lcool&#44; &#237;ndice de massa corporal e frequ&#234;ncia de exerc&#237;cio f&#237;sico&#44; mas maior preval&#234;ncia de antecedentes psiqui&#225;tricos&#44; sintomatologia depressiva e ansiosa&#44; e afetividade negativa&#46; As preval&#234;ncias de hipertens&#227;o&#44; diabetes&#44; dislipidemia e personalidade tipo D foram semelhantes entre homens e mulheres&#46; Globalmente&#44; as mulheres apresentaram piores &#237;ndices de qualidade de vida na maioria das subescalas do SF-36 e encontraram-se diferen&#231;as de g&#233;nero nos preditores de qualidade de vida&#46; Enquanto nas mulheres&#44; a elevada afetividade negativa foi um preditor independente de pior sa&#250;de geral&#44; nos homens&#44; esse efeito foi verificado para &#237;ndices elevados de inibi&#231;&#227;o social e ansiedade&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#245;es</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">As especificidades de g&#233;nero nos fatores de risco cardiovascular devem ser tidas em considera&#231;&#227;o nas estrat&#233;gias de preven&#231;&#227;o prim&#225;ria&#46; As mulheres apresentam qualidade de vida significativamente pior&#44; o que as coloca em maior risco de morbilidade e mortalidade cardiovascular&#44; pelo que as diferen&#231;as de g&#233;nero nos preditores de qualidade de vida devem ser investigados&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Introdu&#231;&#227;o"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "M&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclus&#245;es"
          ]
        ]
      ]
    ]
    "multimedia" => array:4 [
      0 => array:7 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">BMI&#58; body mass index&#59; SD&#58; standard deviation&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Males&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Females&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Age &#40;mean &#177; SD&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">44&#46;0&#177;11&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41&#46;8&#177;10&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;107&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Education &#40;years&#44; mean &#177; SD&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#46;5&#177;3&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#46;1&#177;3&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;378&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Living alone &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;344&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleItalic">Occupation &#40;&#37;&#41;</span></td><td class="td" title="table-entry  " align="char" valign="top">0&#46;782&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Active&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">80&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">81&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Unemployed&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Retired&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Smoking &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;438&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Alcohol consumption &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">50&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleItalic">Exercise &#40;&#37;&#41;</span></td><td class="td" title="table-entry  " align="char" valign="top">0&#46;015&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No exercise&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">36&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Occasional exercise&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">31&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">36&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Regular exercise&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">44&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">BMI &#40;mean &#177; SD&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#46;2&#177;4&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">23&#46;5&#177;3&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hypertension &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;391&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Diabetes &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;079&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Dyslipidemia &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;143&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Chronic illness &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;223&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1004259.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Univariate comparison of participants&#8217; sociodemographic and clinical characteristics by gender&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "tbl0020"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">DS14&#58; Type D Scale-14&#59; HADS-A&#58; Hospital Anxiety and Depression Scale &#8211; Anxiety&#59; HADS-D&#58; Hospital Anxiety and Depression Scale &#8211; Depression&#59; NA&#58; negative affectivity&#59; SF-36&#58; Medical Outcomes Study Short Form&#59; SI&#58; social inhibition&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variables&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Males&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Females&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Depression</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>HADS-D &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#46;8&#177;3&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;8&#177;4&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;022&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>HADS-D &#8805;8 &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;042&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Antidepressant medication &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;053&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Psychiatric history &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;044&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Anxiety</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>HADS-A &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#46;5&#177;3&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#46;1&#177;4&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;236&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>HADS-A &#8805;8 &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;506&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Type D personality &#40;DS14&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Type D &#40;NA &#8805;10 and SI &#8805;10&#41; &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;432&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>NA &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#46;4&#177;6&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;1&#177;7&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;054&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>SI &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#46;0&#177;6&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#46;7&#177;6&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;743&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Quality of life &#40;SF-36 components&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Physical functioning &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">94&#46;5&#177;11&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">90&#46;7&#177;16&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;031&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Role-physical &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97&#46;8&#177;10&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">90&#46;6&#177;24&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bodily pain &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">89&#46;8&#177;13&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;6&#177;20&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>General health &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">76&#46;5&#177;15&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">73&#46;1&#177;18&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;116&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mental health &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">79&#46;7&#177;15&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">71&#46;6&#177;20&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Role-emotional &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">91&#46;6&#177;26&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">77&#46;28&#177;37&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Social functioning &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">89&#46;4&#177;16&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">83&#46;04&#177;21&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;006&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Vitality &#40;mean &#177; SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">72&#46;0&#177;15&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63&#46;4&#177;20&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1004260.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Univariate comparison of participants&#8217; psychometric outcomes by gender&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "tbl0035"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0110" class="elsevierStyleSimplePara elsevierViewall">CI&#58; confidence interval&#59; df&#58; degrees of freedom&#59; HADS-D&#58; Hospital Anxiety and Depression Scale &#8211; Depression&#59; SE&#58; standard error&#46;</p><p id="spar0115" class="elsevierStyleSimplePara elsevierViewall">Backward likelihood ratio method&#59; female gender coded as 1&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Correlates&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">SE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Wald chi-square&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">df&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Odds ratio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">95&#37; CI</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Body mass index&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;209&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;041&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#46;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;812&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;749&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;879&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Occasional exercise&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;364&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;371&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;964&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;695&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;336&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;437&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;326&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Frequent exercise&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;1&#46;016&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;368&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#46;613&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;362&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;176&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;745&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;006&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Alcohol consumption&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;1&#46;445&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;310&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21&#46;787&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;236&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;128&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;432&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">HADS-D &#8805;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;759&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;459&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#46;735&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#46;137&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;869&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#46;256&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;098&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antidepressant medication&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;057&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;549&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;708&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#46;877&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;981&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#46;432&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;054&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1004261.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Summary of multivariate model for the independent correlates of gender &#40;multivariate logistic regression analysis&#41;&#46;</p>"
        ]
      ]
      3 => array:7 [
        "identificador" => "tbl0060"
        "etiqueta" => "Table 4"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0130" class="elsevierStyleSimplePara elsevierViewall">BMI&#58; body mass index&#59; DS14&#58; Type D Scale-14&#59; F&#58; female&#59; HADS-A&#58; Hospital Anxiety and Depression Scale &#8211; Anxiety&#59; HADS-D&#58; Hospital Anxiety and Depression Scale &#8211; Depression&#59; M&#58; male&#59; SF-36&#58; Medical Outcomes Study Short Form&#46;</p><p id="spar0135" class="elsevierStyleSimplePara elsevierViewall">Stepwise procedure&#59; female gender coded as 1&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="16" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">SF-36 &#40;standardized beta coefficients&#41;</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Physical<br>functioning</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Role-physical</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Bodily pain</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">General health</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Mental health</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Role-emotional</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Social functioning</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Vitality</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Predictor variables&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Age&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;002&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Living alone&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Education&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;006&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Occupation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">BMI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;015&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;012&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;010&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Hypertension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;038&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Diabetes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;004&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;027&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;043&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Dyslipidemia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Smoking&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Exercise&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;039&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;024&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Chronic illness&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;014&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;006&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Alcohol consumption&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;032&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;008&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Psychiatric history&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;017&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antidepressant medication&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;011&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;010&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">HADS-A&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;035&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;011&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;002&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">HADS-D&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;009&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">DS 14 &#8211; negative affectivity&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">DS 14 &#8211; Social inhibition&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;007&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;040&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1004262.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0120" class="elsevierStyleSimplePara elsevierViewall">Independent predictors of quality of life dimensions in men and women &#40;multivariate linear regression analysis&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:40 [
            0 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "European Guidelines on cardiovascular disease prevention in clinical practice &#40;version 2012&#41;&#58; the Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46; Perk"
                            1 => "G&#46; De Backer"
                            2 => "H&#46; Gohlke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.atherosclerosis.2012.05.007"
                      "Revista" => array:7 [
                        "tituloSerie" => "Atherosclerosis"
                        "fecha" => "2012"
                        "volumen" => "223"
                        "numero" => "1"
                        "paginaInicial" => "1"
                        "paginaFinal" => "68"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22698795"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Psychosocial stress and cardiovascular risk&#58; current opinion"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Von K&#228;nel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4414/smw.2012.13502"
                      "Revista" => array:6 [
                        "tituloSerie" => "Swiss Med Wkly"
                        "fecha" => "2012"
                        "volumen" => "142"
                        "paginaInicial" => "w13502"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22271452"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0266613813001514"
                          "estado" => "S300"
                          "issn" => "02666138"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Red alert for women&#39;s heart&#58; the urgent need for more research and knowledge on cardiovascular disease in women&#58; proceedings of the workshop held in Brussels on gender differences in cardiovascular disease&#44; 29 September 2010"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;H&#46;E&#46;M&#46; Maas"
                            1 => "Y&#46;T&#46; van der Schouw"
                            2 => "V&#46; Regitz-Zagrosek"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/eurheartj/ehr048"
                      "Revista" => array:7 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2011"
                        "volumen" => "32"
                        "numero" => "11"
                        "paginaInicial" => "1362"
                        "paginaFinal" => "1368"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21406440"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Myocardial ischemia in women&#58; lessons from the NHLBI WISE study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Gulati"
                            1 => "L&#46;J&#46; Shaw"
                            2 => "C&#46;N&#46; Bairey Merz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/clc.21966"
                      "Revista" => array:8 [
                        "tituloSerie" => "Clin Cardiol"
                        "fecha" => "2012"
                        "volumen" => "35"
                        "numero" => "3"
                        "paginaInicial" => "141"
                        "paginaFinal" => "148"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22389117"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673613605930"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ischaemic heart disease in women&#58; are there sex differences in pathophysiology and risk factors&#63; Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "V&#46; Vaccarino"
                            1 => "L&#46; Badimon"
                            2 => "R&#46; Corti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/cvr/cvq394"
                      "Revista" => array:7 [
                        "tituloSerie" => "Cardiovasc Res"
                        "fecha" => "2011"
                        "volumen" => "90"
                        "numero" => "1"
                        "paginaInicial" => "9"
                        "paginaFinal" => "17"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21159671"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The enigma of heart disease in women&#58; new insights may precipitate diagnosis and improve patient outcomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;L&#46; Edwards"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1745-7599.2012.00773.x"
                      "Revista" => array:8 [
                        "tituloSerie" => "J Am Acad Nurse Pract"
                        "fecha" => "2012"
                        "volumen" => "24"
                        "numero" => "10"
                        "paginaInicial" => "574"
                        "paginaFinal" => "578"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23006015"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673602085926"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 13648 controls from 52 countries &#40;the INTERHEART study&#41;&#58; case&#8211;control study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Rosengren"
                            1 => "S&#46; Hawken"
                            2 => "S&#46; Ounpuu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0140-6736(04)17019-0"
                      "Revista" => array:7 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "2004"
                        "volumen" => "364"
                        "numero" => "9438"
                        "paginaInicial" => "953"
                        "paginaFinal" => "962"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15364186"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Symptoms of anxiety and depression and risk of acute myocardial infarction&#58; the HUNT-2 Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46;T&#46; Gustad"
                            1 => "L&#46;E&#46; Laugsand"
                            2 => "I&#46; Janszky"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/eurheartj/eht387"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2014"
                        "volumen" => "35"
                        "paginaInicial" => "1394"
                        "paginaFinal" => "1403"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24057077"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Depression&#58; anxiety and 6-year risk of cardiovascular disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Seldenrijk"
                            1 => "N&#46; Vogelzangs"
                            2 => "N&#46;M&#46; Batelaan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jpsychores.2014.10.007"
                      "Revista" => array:8 [
                        "tituloSerie" => "J Psychosom Res"
                        "fecha" => "2015"
                        "volumen" => "78"
                        "numero" => "2"
                        "paginaInicial" => "123"
                        "paginaFinal" => "129"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25454680"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S014067361460859X"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Early-onset depression&#44; anxiety&#44; and risk of subsequent coronary heart disease&#58; 37-year follow-up of 49&#44;321 young Swedish men"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "I&#46; Janszky"
                            1 => "S&#46; Ahnve"
                            2 => "I&#46; Lundberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jacc.2010.03.033"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Am Coll Cardiol"
                        "fecha" => "2010"
                        "volumen" => "56"
                        "numero" => "1"
                        "paginaInicial" => "31"
                        "paginaFinal" => "37"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20620714"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Anxiety and risk of incident coronary heart disease&#58; a meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;M&#46; Roest"
                            1 => "E&#46;J&#46; Martens"
                            2 => "P&#46; de Jonge"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jacc.2010.03.034"
                      "Revista" => array:8 [
                        "tituloSerie" => "J Am Coll Cardiol"
                        "fecha" => "2010"
                        "volumen" => "56"
                        "numero" => "1"
                        "paginaInicial" => "38"
                        "paginaFinal" => "46"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20620715"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673606693847"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Type D personality as a prognostic factor in heart disease&#58; assessment and mediating mechanisms"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46; Kupper"
                            1 => "J&#46; Denollet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1080/00223890701629797"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Pers Assess"
                        "fecha" => "2007"
                        "volumen" => "89"
                        "numero" => "3"
                        "paginaInicial" => "265"
                        "paginaFinal" => "276"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18001227"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clustering of negative affectivity and social inhibition in the community&#58; prevalence of type D personality as a cardiovascular risk marker"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46; Hausteiner"
                            1 => "D&#46; Klupsch"
                            2 => "R&#46; Emeny"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/PSY.0b013e3181cb8bae"
                      "Revista" => array:7 [
                        "tituloSerie" => "Psychosom Med"
                        "fecha" => "2010"
                        "volumen" => "72"
                        "numero" => "2"
                        "paginaInicial" => "163"
                        "paginaFinal" => "171"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20100886"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Type D personality in the general population&#58; a systematic review of health status&#44; mechanisms of disease&#44; and work-related problems"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46; Mols"
                            1 => "J&#46; Denollet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1186/1477-7525-8-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Health Qual Life Outcomes"
                        "fecha" => "2010"
                        "volumen" => "8"
                        "paginaInicial" => "9"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20096129"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673606693811"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1186/1477-7525-8-9"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;www&#46;hqlo&#46;com&#47;content&#47;"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Self-rated health and morbidity onset among late midlife U&#46;S&#46; adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46; Latham"
                            1 => "C&#46;W&#46; Peek"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/geronb/gbs104"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Gerontol B Psychol Sci Soc Sci"
                        "fecha" => "2013"
                        "volumen" => "68"
                        "paginaInicial" => "107"
                        "paginaFinal" => "116"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23197340"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0266613811000441"
                          "estado" => "S300"
                          "issn" => "02666138"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Relationship of self-rated health with fatal and non-fatal outcomes in cardiovascular disease&#58; a systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46; Mavaddat"
                            1 => "R&#46;A&#46; Parker"
                            2 => "S&#46; Sanderson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0103509"
                      "Revista" => array:6 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2014"
                        "volumen" => "9"
                        "numero" => "7"
                        "paginaInicial" => "e103509"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25076041"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Self-rated health and cardiovascular disease incidence&#58; results from a longitudinal population-based cohort in Norfolk&#44; UK"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "R&#46;M&#46; van der Linde"
                            1 => "N&#46; Mavaddat"
                            2 => "R&#46; Luben"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0065290"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2013"
                        "volumen" => "8"
                        "paginaInicial" => "e65290"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23755212"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association between self-reported general and mental health and adverse outcomes&#58; a retrospective cohort study of 19 625 Scottish adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "Z&#46; Ul-Haq"
                            1 => "D&#46; Mackay"
                            2 => "J&#46; Pell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2014"
                        "volumen" => "9"
                        "paginaInicial" => "1"
                        "paginaFinal" => "10"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0295"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prospective change in health-related quality of life and subsequent mortality among middle-aged and older women"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46;H&#46; Kroenke"
                            1 => "L&#46;D&#46; Kubzansky"
                            2 => "N&#46; Adler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2105/AJPH.2007.114041"
                      "Revista" => array:8 [
                        "tituloSerie" => "Am J Public Health"
                        "fecha" => "2008"
                        "volumen" => "98"
                        "numero" => "11"
                        "paginaInicial" => "2085"
                        "paginaFinal" => "2091"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18511734"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0168827811001826"
                          "estado" => "S300"
                          "issn" => "01688278"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0300"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Self-perceived physical health predicts cardiovascular disease incidence and death among postmenopausal women"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46; Saquib"
                            1 => "R&#46; Brunner"
                            2 => "J&#46; Kubo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1471-2458-13-468"
                      "Revista" => array:6 [
                        "tituloSerie" => "BMC Public Health"
                        "fecha" => "2013"
                        "volumen" => "13"
                        "numero" => "1"
                        "paginaInicial" => "468"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23672763"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0305"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The validity of the Hospital Anxiety and Depression Scale"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "I&#46; Bjelland"
                            1 => "A&#46; Dahl"
                            2 => "T&#46; Haug"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J Psychosom Res"
                        "fecha" => "2002"
                        "volumen" => "52"
                        "numero" => "2"
                        "paginaInicial" => "69"
                        "paginaFinal" => "77"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11832252"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0310"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The hospital anxiety and depression scale"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;S&#46; Zigmond"
                            1 => "R&#46;P&#46; Snaith"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Acta Psychiatr Scand"
                        "fecha" => "1983"
                        "volumen" => "67"
                        "numero" => "6"
                        "paginaInicial" => "361"
                        "paginaFinal" => "370"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6880820"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0315"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Validation study of a Portuguese version of the Hospital Anxiety and Depression Scale"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46; Pais-Ribeiro"
                            1 => "I&#46; Silva"
                            2 => "T&#46; Ferreira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1080/13548500500524088"
                      "Revista" => array:7 [
                        "tituloSerie" => "Psychol Health Med"
                        "fecha" => "2007"
                        "volumen" => "12"
                        "numero" => "2"
                        "paginaInicial" => "225"
                        "paginaFinal" => "235"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17365902"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0320"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Type D personality and depression in a sample of Portuguese patients with acute coronary syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Prata"
                            1 => "S&#46; Ramos"
                            2 => "R&#46; Coelho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Bridging East West Psychiatry"
                        "fecha" => "2008"
                        "volumen" => "VI"
                        "numero" => "1"
                        "paginaInicial" => "34"
                        "paginaFinal" => "42"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0325"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "DS14&#58; standard assessment of negative affectivity&#44; social inhibition&#44; and Type D personality"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Denollet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.psy.0000149256.81953.49"
                      "Revista" => array:7 [
                        "tituloSerie" => "Psychosom Med"
                        "fecha" => "2005"
                        "volumen" => "67"
                        "numero" => "1"
                        "paginaInicial" => "89"
                        "paginaFinal" => "97"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15673629"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0330"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of 3 quality of life measurement tools in patients with chronic heart failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46;V&#46; Sneed"
                            1 => "S&#46; Paul"
                            2 => "Y&#46; Michel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1067/mhl.2001.118303"
                      "Revista" => array:7 [
                        "tituloSerie" => "Heart Lung"
                        "fecha" => "2001"
                        "volumen" => "30"
                        "numero" => "5"
                        "paginaInicial" => "332"
                        "paginaFinal" => "340"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11604975"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0335"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cria&#231;&#227;o da vers&#227;o portuguesa do MOS SF-36&#44; Parte II &#8211; Testes de valida&#231;&#227;o"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46; Ferreira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta M&#233;d Port"
                        "fecha" => "2000"
                        "volumen" => "13"
                        "paginaInicial" => "119"
                        "paginaFinal" => "127"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11026151"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0340"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life and its association with cardiovascular risk factors in a community health care program population"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46;M&#46;B&#46; Martinelli"
                            1 => "B&#46;M&#46; Mizutani"
                            2 => "A&#46; Mutti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Clinics"
                        "fecha" => "2008"
                        "volumen" => "63"
                        "numero" => "6"
                        "paginaInicial" => "783"
                        "paginaFinal" => "788"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19061001"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0345"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The association between educational status and risk factors related to cardiovascular disease in healthy individuals&#58; the ATTICA study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D&#46;B&#46; Panagiotakos"
                            1 => "C&#46;E&#46; Pitsavos"
                            2 => "C&#46;A&#46; Chrysohoou"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S1047-2797(03)00117-0"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Epidemiol"
                        "fecha" => "2004"
                        "volumen" => "14"
                        "numero" => "3"
                        "paginaInicial" => "188"
                        "paginaFinal" => "194"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15036222"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0350"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association of socioeconomic position with health behaviors and mortality"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46; Stringhini"
                            1 => "S&#46; Sabia"
                            2 => "M&#46; Shipley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jama.2010.297"
                      "Revista" => array:7 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "2010"
                        "volumen" => "303"
                        "numero" => "12"
                        "paginaInicial" => "1159"
                        "paginaFinal" => "1166"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20332401"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0355"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Socioeconomic inequalities in health in 22 European countries"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;R&#46; Roskam"
                            1 => "M&#46;M&#46; Schaap"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMsa0707519"
                      "Revista" => array:7 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2008"
                        "volumen" => "358"
                        "numero" => "23"
                        "paginaInicial" => "2468"
                        "paginaFinal" => "2481"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18525043"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0360"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Higher comorbidity of depression and cardiovascular disease in women&#58; a biopsychosocial perspective"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;M&#46; M&#246;ller-Leimk&#252;hler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3109/15622975.2010.523481"
                      "Revista" => array:7 [
                        "tituloSerie" => "World J Biol Psychiatry"
                        "fecha" => "2010"
                        "volumen" => "11"
                        "numero" => "8"
                        "paginaInicial" => "922"
                        "paginaFinal" => "933"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20950120"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0365"
              "etiqueta" => "33"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Does a higher educational level protect against anxiety and depression&#63; The HUNT study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "I&#46; Bjelland"
                            1 => "S&#46; Krokstad"
                            2 => "A&#46; Mykletun"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.socscimed.2007.12.019"
                      "Revista" => array:7 [
                        "tituloSerie" => "Soc Sci Med"
                        "fecha" => "2008"
                        "volumen" => "66"
                        "numero" => "6"
                        "paginaInicial" => "1334"
                        "paginaFinal" => "1345"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18234406"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0370"
              "etiqueta" => "34"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The type-D scale &#40;DS-14&#41; &#8211; norms and prevalence of type-D personality in a population-based representative sample in Germany"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46; Grande"
                            1 => "M&#46; Romppel"
                            2 => "H&#46; Glaesmer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Pers Individ Differ"
                        "fecha" => "2010"
                        "volumen" => "48"
                        "paginaInicial" => "935"
                        "paginaFinal" => "939"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0375"
              "etiqueta" => "35"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Type D personality and chronic pain&#58; construct validity of the DS-14"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46;D&#46; Barnett"
                            1 => "T&#46; Ledoux"
                            2 => "L&#46;M&#46; Garcini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s10880-009-9152-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Psychol Med Settings"
                        "fecha" => "2009"
                        "volumen" => "16"
                        "paginaInicial" => "194"
                        "paginaFinal" => "199"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19266270"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0380"
              "etiqueta" => "36"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Type D personality&#44; quality of life and physical symptoms in the general population&#58; a dimensional analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Stevenson"
                            1 => "L&#46; Williams"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1080/08870446.2013.856433"
                      "Revista" => array:7 [
                        "tituloSerie" => "Psychol Health"
                        "fecha" => "2014"
                        "volumen" => "29"
                        "numero" => "3"
                        "paginaInicial" => "365"
                        "paginaFinal" => "373"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24229061"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib0385"
              "etiqueta" => "37"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Screening for hypertension in children and adolescents to prevent cardiovascular disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Thompson"
                            1 => "T&#46; Dana"
                            2 => "C&#46; Bougatsos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1542/peds.2012-3523"
                      "Revista" => array:7 [
                        "tituloSerie" => "Pediatrics"
                        "fecha" => "2013"
                        "volumen" => "131"
                        "numero" => "3"
                        "paginaInicial" => "490"
                        "paginaFinal" => "525"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23439904"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib0390"
              "etiqueta" => "38"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics of trabeculated myocardium burden in young and apparently healthy adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "H&#46; Tiz&#243;n-Marcos"
                            1 => "M&#46; de la Paz Ricapito"
                            2 => "P&#46; Pibarot"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.amjcard.2014.07.025"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Cardiol"
                        "fecha" => "2014"
                        "volumen" => "114"
                        "numero" => "7"
                        "paginaInicial" => "1094"
                        "paginaFinal" => "1099"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25132331"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bib0395"
              "etiqueta" => "39"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Danish population-based reference data for the EORTC QLQ-C30&#58; associations with gender&#44; age and morbidity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46; Juul"
                            1 => "M&#46;A&#46; Petersen"
                            2 => "B&#46; Holzner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11136-014-0675-y"
                      "Revista" => array:6 [
                        "tituloSerie" => "Qual Life Res"
                        "fecha" => "2014"
                        "volumen" => "23"
                        "paginaInicial" => "2183"
                        "paginaFinal" => "2193"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24676897"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            39 => array:3 [
              "identificador" => "bib0400"
              "etiqueta" => "40"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Gender-specific changes in well-being in older people with coronary heart disease&#58; evidence from the English Longitudinal Study of Ageing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "P&#46; Zaninotto"
                            1 => "A&#46; Sacker"
                            2 => "E&#46; Breeze"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1080/13607863.2015.1020410"
                      "Revista" => array:7 [
                        "tituloSerie" => "Aging Ment Health"
                        "fecha" => "2016"
                        "volumen" => "20"
                        "numero" => "4"
                        "paginaInicial" => "432"
                        "paginaFinal" => "440"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25774880"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/08702551/0000003500000003/v1_201603080050/S0870255116000135/v1_201603080050/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "358"
    "tipo" => "SECCION"
    "pt" => array:2 [
      "titulo" => "Artigos originais"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "pt"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08702551/0000003500000003/v1_201603080050/S0870255116000135/v1_201603080050/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116000135?idApp=UINPBA00004E"
]
Partilhar
Informação da revista
Vol. 35. Núm. 3.
Páginas 153-160 (março 2016)
Partilhar
Partilhar
Baixar PDF
Mais opções do artigo
Visitas
5469
Vol. 35. Núm. 3.
Páginas 153-160 (março 2016)
Original Article
Open Access
Gender differences in quality of life perception and cardiovascular risk in a community sample
Diferenças de género na perceção de qualidade de vida e risco cardiovascular numa amostra comunitária
Visitas
5469
Joana Prataa,
Autor para correspondência
joanappr@gmail.com

Corresponding author.
, Amadeu Quelhas Martinsb,c, Sónia Ramosa, Francisco Rocha-Gonçalvesa, Rui Coelhoc,d
a Unidade de Investigação & Desenvolvimento Cardiovascular, Faculdade de Medicina, Universidade do Porto, Porto, Portugal
b Instituto Nacional de Engenharia Biomédica (INEB), Porto, Portugal
c Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal
d Departamento de Neurociências Clínicas e Saúde Mental, Faculdade de Medicina, Universidade do Porto, Porto, Portugal
Este item recebeu

Under a Creative Commons license
Informação do artigo
Resume
Texto Completo
Bibliografia
Baixar PDF
Estatísticas
Tabelas (4)
Table 1. Univariate comparison of participants’ sociodemographic and clinical characteristics by gender.
Table 2. Univariate comparison of participants’ psychometric outcomes by gender.
Table 3. Summary of multivariate model for the independent correlates of gender (multivariate logistic regression analysis).
Table 4. Independent predictors of quality of life dimensions in men and women (multivariate linear regression analysis).
Mostrar maisMostrar menos
Abstract
Introduction

Self-reported heath and quality of life is an independent predictor of overall and cardiovascular morbidity and mortality, and incident coronary heart disease. However, less is known regarding how gender differences in cardiovascular risk factors impact quality of life perception.

Methods

Primary healthcare users (n=261, 158 women) were screened for cardiovascular risk factors and completed the Medical Outcomes Study Short Form (SF-36).

Results

Women had significantly lower alcohol consumption, body mass index and exercise frequency than men, but more prevalent psychiatric history, depressive and anxiety symptoms, and negative affectivity. Prevalences of hypertension, diabetes, dyslipidemia and type D personality were similar between genders. Women reported significantly worse quality of life on most SF-36 subscales and gender differences were apparent in predictors of quality of life. Moreover, high negative affectivity was an independent predictor of worse general health for women, whereas high social inhibition and high anxiety had a comparable role for men.

Conclusion

Gender specifics in cardiovascular risk factors should be considered in prevention strategies. Women reported significantly worse quality of life, putting them at higher risk for cardiovascular morbidity and mortality. Therefore, gender differences in predictors of quality of life warrant further investigation.

Keywords:
Cardiovascular risk factors
Self-reported health
Quality of life
Gender
Resumo
Introdução

A perceção de qualidade de vida é um preditor independente de mortalidade geral, morbilidade e mortalidade cardiovascular, e incidência de doença cardíaca coronária. Contudo, permanece por esclarecer qual o impacto que as diferenças específicas de género nos fatores de risco cardiovascular têm na perceção de qualidade de vida.

Métodos

Duzentos e sessenta e um utentes dos cuidados primários (158 mulheres) foram rastreados para fatores de risco cardiovascular e preencheram a versão portuguesa do Medical Outcomes Study Short Form (SF-36).

Resultados

As mulheres apresentaram um padrão de menor consumo de álcool, índice de massa corporal e frequência de exercício físico, mas maior prevalência de antecedentes psiquiátricos, sintomatologia depressiva e ansiosa, e afetividade negativa. As prevalências de hipertensão, diabetes, dislipidemia e personalidade tipo D foram semelhantes entre homens e mulheres. Globalmente, as mulheres apresentaram piores índices de qualidade de vida na maioria das subescalas do SF-36 e encontraram-se diferenças de género nos preditores de qualidade de vida. Enquanto nas mulheres, a elevada afetividade negativa foi um preditor independente de pior saúde geral, nos homens, esse efeito foi verificado para índices elevados de inibição social e ansiedade.

Conclusões

As especificidades de género nos fatores de risco cardiovascular devem ser tidas em consideração nas estratégias de prevenção primária. As mulheres apresentam qualidade de vida significativamente pior, o que as coloca em maior risco de morbilidade e mortalidade cardiovascular, pelo que as diferenças de género nos preditores de qualidade de vida devem ser investigados.

Palavras-chave:
Fatores de risco cardiovascular
Saúde auto-relatada
Qualidade de vida
Especificidades de género
Texto Completo
Introduction

Cardiovascular disease (CVD) remains the leading cause of premature death in Europe. Unhealthy lifestyles and psychosocial burden are commonly associated with CVD, and not surprisingly, most of its mortality is preventable through appropriate changes in lifestyle.1 It is well established that psychosocial risk factors interact with biomedical vulnerabilities in the development of CVD, and approximately one third of the attributable risk of acute myocardial infarction can be related to major life events, depression or stress related to work, family or finances. Furthermore, when several psychosocial risk factors cluster in the same individual, the risk for both cardiac events and severe atherosclerosis is substantially increased.2

Men and women have similar biomedical risk factors for CVD, but their relative weight and impact on the pathophysiology of the disease differ markedly.3 Prevention strategies could benefit from taking these risk profile differences into account. Further, gender differences in both disease progression and impact of risk factors could explain why prevalence rates, symptom profiles and medical outcomes still have different prevalences between genders.4,5 Specifically, women with ischemic heart disease have worse outcomes than men regardless of age,4 but usually present much less severe anatomical obstructive lesions and better preserved systolic function.4,6 Clearly, other factors are at play in this apparent contradiction.

It is well established that psychosocial factors such as negative affect and personality traits can increase the risk for CVD.2 However, it is unknown whether they also impact cardiovascular health differentially by gender, thereby contributing to higher CVD morbidity and mortality among women. Specifically, depression is an established risk factor for both CVD patients and healthy individuals, increasing both cardiac morbidity and mortality,7–9 while anxiety has been identified as an independent risk factor for CVD in the community.10,11 Similarly, type D personality is a stable personality construct marked by negative affectivity and social inhibition that combine to produce sustained high levels of mental distress and increased physical symptoms in both CVD patients and healthy participants.12–14 Overall, these psychosocial factors have been consistently linked to CVD risk, but little progress has been made in examining their differential impact by gender.

Self-reported health is an independent predictor of overall and cardiovascular mortality in most studies, and individuals who assess their health as fair or poor have a higher mortality risk than those whose assessment is better.15,16 Moreover, after controlling for sociodemographic characteristics, health care access and risk factors, self-reported health is still a significant and independent predictor of both global morbidity onset15 and CVD incidence.17,18 Specifically, the Medical Outcomes Study Short Form (SF-36) has been shown to predict mortality in community samples.19,20 In particular, the physical component summary of the SF-36 (derived from the sum of scores obtained on the physical functioning, role-physical, bodily pain and general health subscales) exhibits a strong association with mortality, estimates being independent of other physical factors like obesity, physical inactivity or a low-fiber diet.19,20

This study aimed to assess how gender patterns of known cardiovascular risk factors (biomedical and psychosocial) influence self-reported quality of life in a sample of primary health care users without a CVD diagnosis. To the best our knowledge, this study is pioneering in bridging these two important issues.

MethodsParticipants

As part of a prospective study, 261 primary health care users (158 women) were recruited in various health provision settings in the northern region of Portugal. The study design was explained to each participant and written informed consent was obtained. Exclusion criteria comprised either documented or self-reported CVD.

Instruments

Participants were interviewed and assessed for various demographic, behavioral, clinical and psychosocial measures. Questionnaires were used to collect these data.

The Hospital Anxiety and Depression Scale (HADS) is a self-evaluation questionnaire which comprises two subscales, one measuring depression (HAD-D) and the other measuring anxiety (HAD-A).21,22 The HADS has been validated for the Portuguese population.23 A HADS cutoff score greater than 7 in any of the subscales indicates the presence of symptoms, e.g. HAD-D ≥8 indicates depressive symptoms.

Type D personality was assessed using a Portuguese version of the Type D Scale-14 (DS14), which comprises 14 items, seven assessing negative affectivity and seven assessing social inhibition.24 A score of at least 10 on both subscales identifies individuals as having type D (or distressed) personality.25

Quality of life was assessed using the Portuguese version of the Medical Outcomes Study Short Form SF-36,26,27 which comprises 36 questions across eight subscales of functional health and well-being: physical functioning, role-physical, bodily pain, general health, mental health, role-emotional, social functioning and vitality.

Data reduction and analysis

Univariate analysis was used to compare demographic, behavioral, clinical and psychometric variables between genders. Differences between proportions were examined with chi-square tests, while mean comparisons were conducted with Student's t tests. A multivariate logistic regression analysis (backward stepwise method) was conducted to quantify independent associations of previously identified correlates with gender. Adjusted odds ratios (OR) with 95% confidence intervals are reported. A series of multivariate linear regression analyses were conducted separately by gender to identify putative predictors of quality of life scores. The statistical significance level was set at p<0.05.

ResultsUnivariate analysis

Sociodemographic and clinical variables were compared by gender (Table 1). No differences were found regarding age, educational level, living status or occupation. Women presented significantly lower alcohol consumption (p<0.001), lower body mass index (p<0.001) and less exercise activity (p<0.05) than men. Regarding psychosocial measures (Table 2), women scored significantly higher than men for HAD-D (p<0.05), which was corroborated by a greater proportion of women (19% vs. 9.7%) exceeding the scale cutoff for depression (p<0.05). A history of antidepressant medication use (p=0.05) and psychiatric referral and/or complaints (p<0.05) was also more common among women. The prevalence of type D personality was similar between genders, although women scored significantly higher than men in negative affectivity (p=0.05). Finally, women had lower scores in all SF-36 dimensions, indicating an overall perception of poorer health and well-being, and this was statistically significant for all dimensions with the exception of general health (p=0.505).

Table 1.

Univariate comparison of participants’ sociodemographic and clinical characteristics by gender.

Variable  Males  Females 
Age (mean ± SD)  44.0±11.4  41.8±10.2  0.107 
Education (years, mean ± SD)  16.5±3.9  16.1±3.7  0.378 
Living alone (%)  20.4  15.8  0.344 
Occupation (%)0.782 
Active  80.6  81.0   
Unemployed  11.7  9.5   
Retired  7.7  9.5   
Smoking (%)  22.3  26.6  0.438 
Alcohol consumption (%)  50.5  20.3  <0.001 
Exercise (%)0.015 
No exercise  24.3  36.1   
Occasional exercise  31.1  36.1   
Regular exercise  44.6  27.8   
BMI (mean ± SD)  26.2±4.4  23.5±3.8  <0.001 
Hypertension (%)  3.6  10.1  0.391 
Diabetes (%)  4.9  1.3  0.079 
Dyslipidemia (%)  25.2  17.7  0.143 
Chronic illness (%)  4.9  8.9  0.223 

BMI: body mass index; SD: standard deviation.

Table 2.

Univariate comparison of participants’ psychometric outcomes by gender.

Variables  Males  Females 
Depression
HADS-D (mean ± SD)  2.8±3.2  3.8±4.0  0.022 
HADS-D ≥8 (%)  9.7  19.0  0.042 
Antidepressant medication (%)  5.8  13.3  0.053 
Psychiatric history (%)  16.5  27.2  0.044 
Anxiety
HADS-A (mean ± SD)  4.5±3.8  5.1±4.2  0.236 
HADS-A ≥8 (%)  22.3  25.9  0.506 
Type D personality (DS14)
Type D (NA ≥10 and SI ≥10) (%)  22.3  18.4  0.432 
NA (mean ± SD)  7.4±6.4  9.1±7.6  0.054 
SI (mean ± SD)  8.0±6.6  7.7±6.8  0.743 
Quality of life (SF-36 components)
Physical functioning (mean ± SD)  94.5±11.9  90.7±16.5  0.031 
Role-physical (mean ± SD)  97.8±10.6  90.6±24.7  0.001 
Bodily pain (mean ± SD)  89.8±13.3  82.6±20.4  0.001 
General health (mean ± SD)  76.5±15.6  73.1±18.8  0.116 
Mental health (mean ± SD)  79.7±15.6  71.6±20.5  <0.001 
Role-emotional (mean ± SD)  91.6±26.7  77.28±37.0  <0.001 
Social functioning (mean ± SD)  89.4±16.0  83.04±21.0  0.006 
Vitality (mean ± SD)  72.0±15.6  63.4±20.1  <0.001 

DS14: Type D Scale-14; HADS-A: Hospital Anxiety and Depression Scale – Anxiety; HADS-D: Hospital Anxiety and Depression Scale – Depression; NA: negative affectivity; SF-36: Medical Outcomes Study Short Form; SI: social inhibition.

Multivariate analysis

Table 3 shows the multivariate logistic regression model (Nagelkerke R2=0.32) obtained for the independent correlates of gender. Lower body mass index (p<0.001), less frequent exercise (p<0.01), and less alcohol consumption (p<0.001) were all independently associated with women (Table 3). Further, women were more than twice as likely than men to use antidepressants (OR 2.877, p=0.05) and to exceed the HADS-D cutoff for depression (OR 2.137, p=0.098).

Table 3.

Summary of multivariate model for the independent correlates of gender (multivariate logistic regression analysis).

Correlates  SE  Wald chi-square  df  Odds ratio  95% CI
Body mass index  −0.209  0.041  26.06  0.812  0.749  0.879  0.000 
Occasional exercise  −0.364  0.371  0.964  0.695  0.336  1.437  0.326 
Frequent exercise  −1.016  0.368  7.613  0.362  0.176  0.745  0.006 
Alcohol consumption  −1.445  0.310  21.787  0.236  0.128  0.432  0.000 
HADS-D ≥8  0.759  0.459  2.735  2.137  0.869  5.256  0.098 
Antidepressant medication  1.057  0.549  3.708  2.877  0.981  8.432  0.054 

CI: confidence interval; df: degrees of freedom; HADS-D: Hospital Anxiety and Depression Scale – Depression; SE: standard error.

Backward likelihood ratio method; female gender coded as 1.

Table 4 displays the results of the multivariate linear regression analysis of participants’ quality of life scores (only statistically significant scores are shown). Among men, an increased sense of ‘physical functioning’ was predicted by lower body mass, more frequent exercise, less prevalent chronic illness and less antidepressant use, alongside a lower score for social inhibition (DS14). In women, living alone, higher education and more exercise predicted better ‘physical functioning’, while higher prevalences of hypertension, diabetes and antidepressant use were related to worse ‘physical functioning’. Role limitations due to physical problems (‘role-physical’ subscale, on which higher scores indicate less limitation due to physical problems) were mainly associated with the prevalence of diabetes in men. In women, higher body mass, higher depression scores (HADS-D) and more antidepressant use predicted more role limitations due to physical problems. Not surprisingly, a higher prevalence of hypertension and other chronic illness was predictive of more pain complaints in men (‘bodily pain’ subscale, on which higher scores indicate less pain complaints), whereas more frequent exercise was predictive of less pain complaints. In women, more pain complaints were predicted by higher body mass, higher prevalences of diabetes and psychiatric referrals, and higher DS14 scores for negative affectivity. In men, better ‘general health’ was predicted by younger age, a lower prevalence of diabetes, and lower anxiety (HADS-A) and social inhibition (DS14) scores, while better ‘mental health’ was solely predicted by lower scores on the anxiety (HADS-A), depression (HADS-D) and negative affectivity (DS14) scales. In women, however, better ‘general health’ was predicted by lower body mass, less prevalence of diabetes and other chronic illness, and lower negative affectivity scores (DS14). Similarly to men, women reporting better ‘mental health’ were those with lower anxiety (HADS-A), depression (HADS-D) and negative affectivity (DS14) scores. Lower depression scores (HADS-D) predicted less role limitations due to emotional problems (a higher score on the ‘role-emotional’ dimension), while better ‘social functioning’ was associated with lower HADS-A scores in anxiety in men. In women, less role limitations due to emotional problems (a higher score on the ‘role-emotional’ dimension) were predicted by less alcohol consumption, and lower depression (HADS-D) and negative affectivity (DS14) scores. Concomitantly, better ‘social functioning’ was also predicted by less alcohol consumption and lower anxiety (HADS-A), depression (HADS-D) and social inhibition (DS14) scores. Finally, men with lower educational level and lower scores on the anxiety (HADS-A), depression (HADS-D) and social inhibition (DS14) scales had a greater sense of ‘vitality’. In women, greater vitality was significantly predicted by lower depression (HADS-D) and negative affectivity (DS14) scores.

Table 4.

Independent predictors of quality of life dimensions in men and women (multivariate linear regression analysis).

  SF-36 (standardized beta coefficients)
  Physical
functioning
Role-physicalBodily painGeneral healthMental healthRole-emotionalSocial functioningVitality
Predictor variables 
Age              0.002                   
Living alone    <0.001                             
Education    <0.001                          0.006   
Occupation                                 
BMI  0.015      0.012    0.010    0.000                 
Hypertension    0.005      0.038                       
Diabetes    0.004  0.005      0.027  0.043  0.001                 
Dyslipidemia                                 
Smoking                                 
Exercise  0.001  0.039      0.024                       
Chronic illness  <0.001        0.014      0.006                 
Alcohol consumption                        0.032    0.008     
Psychiatric history            0.017                     
Antidepressant medication  <0.05  0.011    0.010                         
HADS-A              0.035    <0.001  <0.001      <0.001  0.011  0.002   
HADS-D        0.009          <0.001  <0.001  <0.001  <0.001    <0.001  0.001  <0.001 
DS 14 – negative affectivity            0.005    0.000  <0.001  <0.001    0.001        <0.001 
DS 14 – Social inhibition  <0.001            0.007              0.003  0.040  0. 

BMI: body mass index; DS14: Type D Scale-14; F: female; HADS-A: Hospital Anxiety and Depression Scale – Anxiety; HADS-D: Hospital Anxiety and Depression Scale – Depression; M: male; SF-36: Medical Outcomes Study Short Form.

Stepwise procedure; female gender coded as 1.

Discussion

This study sought to examine how gender patterns of cardiovascular risk factors associate with self-reported quality of life in a sample of primary health care users without a CVD diagnosis. Our main findings pinpointed gender differences in risk factors mostly related to participants’ life style and mental/affective status. Specifically, women revealed significantly lower rates of alcohol consumption and exercise but presented more depressive symptoms and negative affectivity. In agreement with these findings, a history of antidepressant use and psychiatric referrals was also more common among women. Further, our multivariate analysis expanded these findings to confirm most of these risk factors as independent correlates for females.

Interestingly, traditional biomedical CVD risk factors, such as smoking, hypertension, diabetes and dyslipidemia, did not differ between genders. This finding partially supports the hypothesis of a different pathophysiological impact of CVD risk for female gender, possibly through the deleterious action of psychosocial risk factors like those mentioned above. In line with this suggestion, the quality of life assessment for female participants indicated overall poorer health and well-being, despite the absence of any objective gender difference in biomedical risk factors, which is in agreement with other studies that also reported lower quality of life scores for women.28

It is still not fully understood how educational level can influence the risk for CVD. Several studies have examined this and suggest that education partially affects this risk through increased prevalence of CVD risk factors at lower educational levels.29 In our study, despite the high educational level of the participants, we found a relatively high prevalence of risk factors which are mostly lifestyle dependent. We cannot exclude the possibility that our high educational level sampling masked any latent differences in traditional CVD risk factors. However, 36.1% of the women in our study did not exercise at all, which is higher than expected as studies have shown that lower education or occupation levels are usually associated with a higher prevalence of sedentariness among women.30 Also, no gender differences were found in smoking patterns, with the majority of participants being non-smokers. This follows the trend of western populations, where the prevalence of smoking is declining for both genders and increasing in lower social classes.31

Women had a prevalence of depressive symptoms that was more than twice that reported by men. In addition, psychiatric referrals and antidepressant use were also more prevalent among women. These data are in line with previous evidence showing that women are about twice as likely as men to experience depression.32 In addition, 22.3% of men and 25.9% of women were classified as anxious according to the HADS-A. This finding is apparently at odds with studies indicating a protective effect of educational level against anxiety and depression,33 but it might derive from an overall young sample. Finally, the prevalence of type D personality was similar between genders, replicating previous research.34,35 Nevertheless, women did score significantly higher than men on the negative affectivity subscale of the DS14, which has been considered elsewhere as a key predictor of worse subjective health outcomes.36

This study examined how gender patterns in CVD risk influence self-reported health and quality of life perception. Women reported significantly worse levels of well-being and health across most subscales of the SF-36 questionnaire, with the exception of the general health subscale (for which scores did not reach statistical significance, although they were still lower). Based on the findings of others,15,17,18 this could indicate that, in this study, women faced a higher risk for cardiovascular morbidity and mortality. Firstly, recent evidence indicates that poor self-rated health is strongly associated with cardiovascular mortality, irrespective of prior CVD,16 and with the incidence of coronary heart disease.17,18 Secondly, the physical health component of the SF-36 has been specifically identified as a strong predictor of CVD incidence and death in post-menopausal women.20 Thirdly, although the mechanisms underlying this association remain speculative, the fact is that the SF-36 physical health component exhibits a strong association with mortality, while this effect is independent of other risk factors like obesity, physical inactivity or diet.19,20

Among the gender distinctiveness apparent in the multivariate linear regression profiles of the quality of life scores, role limitations due to physical problems (‘role-physical’) and more pain complaints (‘bodily pain’) were predicted by psychosocial risk factors such as depression and negative affectivity in women, whereas in men these two dimensions appear to depend more on biomedical factors such as diabetes, hypertension, exercise and chronic illness. A recent study with healthy participants found that type D personality was significantly associated with lower quality of life and more physical symptoms, with the negative affectivity component standing out as the key predictor of subjective health outcomes.36 In our study, high negative affectivity was a strong independent predictor of worse general health for women, whereas high social inhibition and high anxiety had a comparable role for men. These results are worth highlighting given the predictive value of the SF-36 physical health component for CVD mortality and morbidity. Indeed, this distinct gender pattern may be the key to the differential impact of psychosocial risk factors on CVD risk, and should therefore be examined.

This study involves a population with highly specific characteristics, which is relevant for the following reasons. Firstly, our participants were relatively young and had a high educational level. While this requires caution regarding the generalization of findings to other populations, the fact is that studies aiming to enhance CVD prevention tend to be conducted with increasingly young samples.37,38 Secondly, our investigation followed an observational cross-sectional design, which precludes any generalization concerning longitudinal trends of the associations found. Thirdly, most of the data collection relied on self-reporting, hence reflecting the individual's assessment of currently experienced symptoms. Although memory bias could have distorted the data, such an effect is likely to be reflected similarly within the whole sample. Finally, multivariate analyses of quality of life scores were conducted separately by gender. On the one hand, sample size was limited in order to run meaningful multivariate linear regression comparisons between genders. On the other hand, the available evidence regarding self-rated health by gender is still inconsistent, with studies indicating no differences,39 a tendency for men to assess their health more positively than women,28 or even the opposite.40

Conclusions and implications for practice

This study shows that community participants without documented CVD present gender-specific patterns of CVD risk factors and that these impact quality of life differentially. In our view, these gender specifics need to be considered in health prevention strategies, given the predictive value of quality of life for cardiovascular morbidity and mortality.

Ethical disclosuresProtection of human and animal subjects

The authors declare that no experiments were performed on humans or animals for this study.

Confidentiality of data

The authors declare that they have followed the protocols of their work center on the publication of patient data.

Right to privacy and informed consent

The authors declare that no patient data appear in this article.

Conflicts of interest and funding

The lead author received funding from Fundação para a Ciência e a Tecnologia in the form of a PhD grant (SFRH/BD/70327/2010). The other authors have no conflicts of interest to declare.

References
[1]
J. Perk, G. De Backer, H. Gohlke, et al.
European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): the Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice.
[2]
R. Von Känel.
Psychosocial stress and cardiovascular risk: current opinion.
Swiss Med Wkly, 142 (2012), pp. w13502
[3]
A.H.E.M. Maas, Y.T. van der Schouw, V. Regitz-Zagrosek, et al.
Red alert for women's heart: the urgent need for more research and knowledge on cardiovascular disease in women: proceedings of the workshop held in Brussels on gender differences in cardiovascular disease, 29 September 2010.
Eur Heart J, 32 (2011), pp. 1362-1368
[4]
M. Gulati, L.J. Shaw, C.N. Bairey Merz.
Myocardial ischemia in women: lessons from the NHLBI WISE study.
Clin Cardiol, 35 (2012), pp. 141-148
[5]
V. Vaccarino, L. Badimon, R. Corti, et al.
Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology.
Cardiovasc Res, 90 (2011), pp. 9-17
[6]
M.L. Edwards.
The enigma of heart disease in women: new insights may precipitate diagnosis and improve patient outcomes.
J Am Acad Nurse Pract, 24 (2012), pp. 574-578
[7]
A. Rosengren, S. Hawken, S. Ounpuu, et al.
Association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 13648 controls from 52 countries (the INTERHEART study): case–control study.
[8]
L.T. Gustad, L.E. Laugsand, I. Janszky, et al.
Symptoms of anxiety and depression and risk of acute myocardial infarction: the HUNT-2 Study.
Eur Heart J, 35 (2014), pp. 1394-1403
[9]
A. Seldenrijk, N. Vogelzangs, N.M. Batelaan, et al.
Depression: anxiety and 6-year risk of cardiovascular disease.
J Psychosom Res, 78 (2015), pp. 123-129
[10]
I. Janszky, S. Ahnve, I. Lundberg, et al.
Early-onset depression, anxiety, and risk of subsequent coronary heart disease: 37-year follow-up of 49,321 young Swedish men.
J Am Coll Cardiol, 56 (2010), pp. 31-37
[11]
A.M. Roest, E.J. Martens, P. de Jonge, et al.
Anxiety and risk of incident coronary heart disease: a meta-analysis.
J Am Coll Cardiol, 56 (2010), pp. 38-46
[12]
N. Kupper, J. Denollet.
Type D personality as a prognostic factor in heart disease: assessment and mediating mechanisms.
J Pers Assess, 89 (2007), pp. 265-276
[13]
C. Hausteiner, D. Klupsch, R. Emeny, et al.
Clustering of negative affectivity and social inhibition in the community: prevalence of type D personality as a cardiovascular risk marker.
Psychosom Med, 72 (2010), pp. 163-171
[14]
F. Mols, J. Denollet.
Type D personality in the general population: a systematic review of health status, mechanisms of disease, and work-related problems.
[15]
K. Latham, C.W. Peek.
Self-rated health and morbidity onset among late midlife U.S. adults.
J Gerontol B Psychol Sci Soc Sci, 68 (2013), pp. 107-116
[16]
N. Mavaddat, R.A. Parker, S. Sanderson, et al.
Relationship of self-rated health with fatal and non-fatal outcomes in cardiovascular disease: a systematic review and meta-analysis.
[17]
R.M. van der Linde, N. Mavaddat, R. Luben, et al.
Self-rated health and cardiovascular disease incidence: results from a longitudinal population-based cohort in Norfolk, UK.
[18]
Z. Ul-Haq, D. Mackay, J. Pell.
Association between self-reported general and mental health and adverse outcomes: a retrospective cohort study of 19 625 Scottish adults.
PLoS ONE, 9 (2014), pp. 1-10
[19]
C.H. Kroenke, L.D. Kubzansky, N. Adler, et al.
Prospective change in health-related quality of life and subsequent mortality among middle-aged and older women.
Am J Public Health, 98 (2008), pp. 2085-2091
[20]
N. Saquib, R. Brunner, J. Kubo, et al.
Self-perceived physical health predicts cardiovascular disease incidence and death among postmenopausal women.
BMC Public Health, 13 (2013), pp. 468
[21]
I. Bjelland, A. Dahl, T. Haug, et al.
The validity of the Hospital Anxiety and Depression Scale.
J Psychosom Res, 52 (2002), pp. 69-77
[22]
A.S. Zigmond, R.P. Snaith.
The hospital anxiety and depression scale.
Acta Psychiatr Scand, 67 (1983), pp. 361-370
[23]
J. Pais-Ribeiro, I. Silva, T. Ferreira, et al.
Validation study of a Portuguese version of the Hospital Anxiety and Depression Scale.
Psychol Health Med, 12 (2007), pp. 225-235
[24]
J. Prata, S. Ramos, R. Coelho.
Type D personality and depression in a sample of Portuguese patients with acute coronary syndrome.
Bridging East West Psychiatry, VI (2008), pp. 34-42
[25]
J. Denollet.
DS14: standard assessment of negative affectivity, social inhibition, and Type D personality.
[26]
N.V. Sneed, S. Paul, Y. Michel, et al.
Evaluation of 3 quality of life measurement tools in patients with chronic heart failure.
Heart Lung, 30 (2001), pp. 332-340
[27]
P. Ferreira.
Criação da versão portuguesa do MOS SF-36, Parte II – Testes de validação.
Acta Méd Port, 13 (2000), pp. 119-127
[28]
L.M.B. Martinelli, B.M. Mizutani, A. Mutti, et al.
Quality of life and its association with cardiovascular risk factors in a community health care program population.
Clinics, 63 (2008), pp. 783-788
[29]
D.B. Panagiotakos, C.E. Pitsavos, C.A. Chrysohoou, et al.
The association between educational status and risk factors related to cardiovascular disease in healthy individuals: the ATTICA study.
Ann Epidemiol, 14 (2004), pp. 188-194
[30]
S. Stringhini, S. Sabia, M. Shipley, et al.
Association of socioeconomic position with health behaviors and mortality.
JAMA, 303 (2010), pp. 1159-1166
[31]
A.R. Roskam, M.M. Schaap.
Socioeconomic inequalities in health in 22 European countries.
N Engl J Med, 358 (2008), pp. 2468-2481
[32]
A.M. Möller-Leimkühler.
Higher comorbidity of depression and cardiovascular disease in women: a biopsychosocial perspective.
World J Biol Psychiatry, 11 (2010), pp. 922-933
[33]
I. Bjelland, S. Krokstad, A. Mykletun, et al.
Does a higher educational level protect against anxiety and depression? The HUNT study.
Soc Sci Med, 66 (2008), pp. 1334-1345
[34]
G. Grande, M. Romppel, H. Glaesmer, et al.
The type-D scale (DS-14) – norms and prevalence of type-D personality in a population-based representative sample in Germany.
Pers Individ Differ, 48 (2010), pp. 935-939
[35]
M.D. Barnett, T. Ledoux, L.M. Garcini, et al.
Type D personality and chronic pain: construct validity of the DS-14.
J Clin Psychol Med Settings, 16 (2009), pp. 194-199
[36]
C. Stevenson, L. Williams.
Type D personality, quality of life and physical symptoms in the general population: a dimensional analysis.
Psychol Health, 29 (2014), pp. 365-373
[37]
M. Thompson, T. Dana, C. Bougatsos, et al.
Screening for hypertension in children and adolescents to prevent cardiovascular disease.
Pediatrics, 131 (2013), pp. 490-525
[38]
H. Tizón-Marcos, M. de la Paz Ricapito, P. Pibarot, et al.
Characteristics of trabeculated myocardium burden in young and apparently healthy adults.
Am J Cardiol, 114 (2014), pp. 1094-1099
[39]
T. Juul, M.A. Petersen, B. Holzner, et al.
Danish population-based reference data for the EORTC QLQ-C30: associations with gender, age and morbidity.
Qual Life Res, 23 (2014), pp. 2183-2193
[40]
P. Zaninotto, A. Sacker, E. Breeze, et al.
Gender-specific changes in well-being in older people with coronary heart disease: evidence from the English Longitudinal Study of Ageing.
Aging Ment Health, 20 (2016), pp. 432-440
Copyright © 2016. Sociedade Portuguesa de Cardiologia
Baixar PDF
Idiomas
Revista Portuguesa de Cardiologia
Opções de artigo
Ferramentas
en pt

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

Ao assinalar que é «Profissional de Saúde», declara conhecer e aceitar que a responsável pelo tratamento dos dados pessoais dos utilizadores da página de internet da Revista Portuguesa de Cardiologia (RPC), é esta entidade, com sede no Campo Grande, n.º 28, 13.º, 1700-093 Lisboa, com os telefones 217 970 685 e 217 817 630, fax 217 931 095 e com o endereço de correio eletrónico revista@spc.pt. Declaro para todos os fins, que assumo inteira responsabilidade pela veracidade e exatidão da afirmação aqui fornecida.