array:26 [
  "pii" => "S0870255117303487"
  "issn" => "08702551"
  "doi" => "10.1016/j.repc.2017.05.002"
  "estado" => "S300"
  "fechaPublicacion" => "2017-06-01"
  "aid" => "1006"
  "copyright" => "Sociedade Portuguesa de Cardiologia"
  "copyrightAnyo" => "2017"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "dis"
  "cita" => "Rev Port Cardiol. 2017;36:461-3"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2989
    "formatos" => array:3 [
      "EPUB" => 166
      "HTML" => 2364
      "PDF" => 459
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:20 [
      "pii" => "S2174204917301307"
      "issn" => "21742049"
      "doi" => "10.1016/j.repce.2017.05.002"
      "estado" => "S300"
      "fechaPublicacion" => "2017-06-01"
      "aid" => "1006"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "dis"
      "cita" => "Rev Port Cardiol. 2017;36:461-3"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 2502
        "formatos" => array:3 [
          "EPUB" => 153
          "HTML" => 1998
          "PDF" => 351
        ]
      ]
      "en" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Editorial comment</span>"
        "titulo" => "Early detection by non-invasive methods of predisposition to atrial remodeling in hypertension"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "461"
            "paginaFinal" => "463"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Predisposi&#231;&#227;o para remodelagem auricular na hipertens&#227;o arterial - dete&#231;&#227;o precoce por meios n&#227;o invasivos"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Luiz Menezes Falc&#227;o"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "Luiz"
                "apellidos" => "Menezes Falc&#227;o"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "pt" => array:9 [
          "pii" => "S0870255117303487"
          "doi" => "10.1016/j.repc.2017.05.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "pt"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117303487?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917301307?idApp=UINPBA00004E"
      "url" => "/21742049/0000003600000006/v1_201707020042/S2174204917301307/v1_201707020042/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S0870255116302323"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2016.11.009"
    "estado" => "S300"
    "fechaPublicacion" => "2017-06-01"
    "aid" => "1015"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Cardiol. 2017;36:465-72"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2629
      "formatos" => array:3 [
        "EPUB" => 183
        "HTML" => 1912
        "PDF" => 534
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review Article</span>"
      "titulo" => "Mid-regional pro-adrenomedullin and ST2 in heart failure&#58; Contributions to diagnosis and prognosis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "465"
          "paginaFinal" => "472"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "A MR-proadrenomedulina e o ST2 na insufici&#234;ncia card&#237;aca&#58; contribui&#231;&#227;o para o diagn&#243;stico e progn&#243;stico"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1016
              "Ancho" => 2333
              "Tamanyo" => 68545
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Schematic representation of the interleukin-33 &#40;IL-33&#41;&#47;ST2 pathway&#46; IL-33 exerts its biological actions when it binds to the ST2L isoform&#46; In situations of myocardial stress&#44; the IL-33&#47;ST2L interaction appears to have a cardioprotective effect&#46; Soluble ST2 acts as a decoy receptor&#44; preventing the beneficial effects of IL-33&#47;ST2L signaling&#46; IL-33&#58; interleukin-33&#59; sST2&#58; soluble ST2&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Daniela Lopes, Luiz Menezes Falc&#227;o"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Daniela"
              "apellidos" => "Lopes"
            ]
            1 => array:2 [
              "nombre" => "Luiz"
              "apellidos" => "Menezes Falc&#227;o"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2174204917301745"
        "doi" => "10.1016/j.repce.2016.11.012"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917301745?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116302323?idApp=UINPBA00004E"
    "url" => "/08702551/0000003600000006/v2_201706240150/S0870255116302323/v2_201706240150/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S0870255117303475"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2016.10.012"
    "estado" => "S300"
    "fechaPublicacion" => "2017-06-01"
    "aid" => "1005"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Cardiol. 2017;36:453-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3082
      "formatos" => array:3 [
        "EPUB" => 178
        "HTML" => 2486
        "PDF" => 418
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Early changes in atrial conduction times in hypertensive patients with elevated pulse pressure"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "453"
          "paginaFinal" => "459"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Altera&#231;&#245;es precoces nos tempos de condu&#231;&#227;o auricular nos doentes hipertensos com press&#227;o de pulso elevada"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 883
              "Ancho" => 3332
              "Tamanyo" => 198713
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Pearson&#39;s correlation analysis demonstrating the correlation between pulse pressure and atrial electromechanical delay&#46; EMD&#58; electromechanical delay&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Tolga &#199;imen, Hamza Sunman, Tolga Han Efe, Ahmet Akyel, Kadriye Yayla, Haluk Furkan &#350;ahan, Murat Bilgin, Lale Din&#231; Asarc&#305;kl&#305;, Ali Nallbani, Mehmet Do&#287;an, Sad&#305;k A&#231;&#305;kel, Ekrem Yeter"
          "autores" => array:12 [
            0 => array:2 [
              "nombre" => "Tolga"
              "apellidos" => "&#199;imen"
            ]
            1 => array:2 [
              "nombre" => "Hamza"
              "apellidos" => "Sunman"
            ]
            2 => array:2 [
              "nombre" => "Tolga Han"
              "apellidos" => "Efe"
            ]
            3 => array:2 [
              "nombre" => "Ahmet"
              "apellidos" => "Akyel"
            ]
            4 => array:2 [
              "nombre" => "Kadriye"
              "apellidos" => "Yayla"
            ]
            5 => array:2 [
              "nombre" => "Haluk Furkan"
              "apellidos" => "&#350;ahan"
            ]
            6 => array:2 [
              "nombre" => "Murat"
              "apellidos" => "Bilgin"
            ]
            7 => array:2 [
              "nombre" => "Lale Din&#231;"
              "apellidos" => "Asarc&#305;kl&#305;"
            ]
            8 => array:2 [
              "nombre" => "Ali"
              "apellidos" => "Nallbani"
            ]
            9 => array:2 [
              "nombre" => "Mehmet"
              "apellidos" => "Do&#287;an"
            ]
            10 => array:2 [
              "nombre" => "Sad&#305;k"
              "apellidos" => "A&#231;&#305;kel"
            ]
            11 => array:2 [
              "nombre" => "Ekrem"
              "apellidos" => "Yeter"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2174204917301733"
        "doi" => "10.1016/j.repce.2016.10.022"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917301733?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117303475?idApp=UINPBA00004E"
    "url" => "/08702551/0000003600000006/v2_201706240150/S0870255117303475/v2_201706240150/en/main.assets"
  ]
  "asociados" => array:1 [
    0 => array:20 [
      "pii" => "S0870255117303475"
      "issn" => "08702551"
      "doi" => "10.1016/j.repc.2016.10.012"
      "estado" => "S300"
      "fechaPublicacion" => "2017-06-01"
      "aid" => "1005"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Rev Port Cardiol. 2017;36:453-9"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 3082
        "formatos" => array:3 [
          "EPUB" => 178
          "HTML" => 2486
          "PDF" => 418
        ]
      ]
      "en" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
        "titulo" => "Early changes in atrial conduction times in hypertensive patients with elevated pulse pressure"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "tieneResumen" => array:2 [
          0 => "en"
          1 => "pt"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "453"
            "paginaFinal" => "459"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Altera&#231;&#245;es precoces nos tempos de condu&#231;&#227;o auricular nos doentes hipertensos com press&#227;o de pulso elevada"
          ]
        ]
        "contieneResumen" => array:2 [
          "en" => true
          "pt" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figure 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 883
                "Ancho" => 3332
                "Tamanyo" => 198713
              ]
            ]
            "descripcion" => array:1 [
              "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Pearson&#39;s correlation analysis demonstrating the correlation between pulse pressure and atrial electromechanical delay&#46; EMD&#58; electromechanical delay&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Tolga &#199;imen, Hamza Sunman, Tolga Han Efe, Ahmet Akyel, Kadriye Yayla, Haluk Furkan &#350;ahan, Murat Bilgin, Lale Din&#231; Asarc&#305;kl&#305;, Ali Nallbani, Mehmet Do&#287;an, Sad&#305;k A&#231;&#305;kel, Ekrem Yeter"
            "autores" => array:12 [
              0 => array:2 [
                "nombre" => "Tolga"
                "apellidos" => "&#199;imen"
              ]
              1 => array:2 [
                "nombre" => "Hamza"
                "apellidos" => "Sunman"
              ]
              2 => array:2 [
                "nombre" => "Tolga Han"
                "apellidos" => "Efe"
              ]
              3 => array:2 [
                "nombre" => "Ahmet"
                "apellidos" => "Akyel"
              ]
              4 => array:2 [
                "nombre" => "Kadriye"
                "apellidos" => "Yayla"
              ]
              5 => array:2 [
                "nombre" => "Haluk Furkan"
                "apellidos" => "&#350;ahan"
              ]
              6 => array:2 [
                "nombre" => "Murat"
                "apellidos" => "Bilgin"
              ]
              7 => array:2 [
                "nombre" => "Lale Din&#231;"
                "apellidos" => "Asarc&#305;kl&#305;"
              ]
              8 => array:2 [
                "nombre" => "Ali"
                "apellidos" => "Nallbani"
              ]
              9 => array:2 [
                "nombre" => "Mehmet"
                "apellidos" => "Do&#287;an"
              ]
              10 => array:2 [
                "nombre" => "Sad&#305;k"
                "apellidos" => "A&#231;&#305;kel"
              ]
              11 => array:2 [
                "nombre" => "Ekrem"
                "apellidos" => "Yeter"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2174204917301733"
          "doi" => "10.1016/j.repce.2016.10.022"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917301733?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117303475?idApp=UINPBA00004E"
      "url" => "/08702551/0000003600000006/v2_201706240150/S0870255117303475/v2_201706240150/en/main.assets"
    ]
  ]
  "pt" => array:12 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Coment&#225;rio Editorial</span>"
    "titulo" => "Predisposi&#231;&#227;o para remodelagem auricular na hipertens&#227;o arterial - dete&#231;&#227;o precoce por meios n&#227;o invasivos"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "461"
        "paginaFinal" => "463"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Luiz Menezes Falc&#227;o"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "Luiz"
            "apellidos" => "Menezes Falc&#227;o"
            "email" => array:1 [
              0 => "luizmfalcao&#64;sapo&#46;pt"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Faculdade de Medicina de Lisboa&#46; Hospital de Santa Maria&#47;Centro Hospitalar Lisboa Norte&#44; Lisboa&#44; Portugal"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Early detection by non&#8208;invasive methods of predisposition to atrial remodeling in hypertension"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Hipertens&#227;o arterial com valores tensionais persistentemente elevados &#233; um dos principais fatores de risco cardiovascular&#46; A hipertens&#227;o arterial &#233; respons&#225;vel por uma sobrecarga de press&#227;o que favorece a remodelagem auricular ocasionando altera&#231;&#245;es estruturais e el&#233;tricas<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1&#44;2</span></a>&#46; As consequ&#234;ncias fazem&#8208;se sentir a v&#225;rios n&#237;veis e&#44; nomeadamente&#44; no aumento do risco de instala&#231;&#227;o de fibrilha&#231;&#227;o auricular &#40;FA&#41; que se agrava com o avan&#231;ar da idade<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">3</span></a>&#46; Como est&#225; bem estabelecido&#44; a FA tem importante repercuss&#227;o ao n&#237;vel do d&#233;bito card&#237;aco e associa&#8208;se a um risco quatro a cinco vezes superior de acidente vascular cerebral &#40;AVC&#41; isqu&#233;mico cardioemb&#243;lico<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">4&#44;5</span></a>&#46; Tamb&#233;m o risco de mortalidade fica muito acrescido pela presen&#231;a desta entidade<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">6</span></a>&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">O atraso eletromec&#226;nico interauricular e o prolongamento do tempo de ativa&#231;&#227;o auricular total t&#234;m sido ligados ao aumento da incid&#234;ncia de FA<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">3&#44;7&#44;8</span></a>&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">O prolongamento do tempo de condu&#231;&#227;o auricular fornece indica&#231;&#227;o de remodelagem estrutural e el&#233;trica&#44; tendo assim vantagem sobre a medi&#231;&#227;o da dimens&#227;o da aur&#237;cula esquerda &#40;AE&#41; ou do &#237;ndice do volume da AE<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1&#44;9</span></a>&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">O &#237;ndice de massa ventricular esquerdo &#40;IMVE&#41; est&#225; associado com um prolongamento do tempo interauricular e com o tempo de acoplamento auricular esquerdo<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">1</span></a>&#46; A gravidade da hipertrofia ventricular esquerda parece estar associada&#44; entre outros fatores&#44; com a instala&#231;&#227;o de FA&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Existe demonstra&#231;&#227;o de que a terap&#234;utica farmacol&#243;gica&#44; com a redu&#231;&#227;o da press&#227;o arterial &#40;PA&#41; e consequente redu&#231;&#227;o da massa ventricular esquerda&#44; pode permitir reduzir o aparecimento da FA<a class="elsevierStyleCrossRefs" href="#bib0180"><span class="elsevierStyleSup">10&#8211;12</span></a>&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Dados do <span class="elsevierStyleItalic">Framingham Heart Study</span> j&#225; tinham evidenciado haver uma rela&#231;&#227;o entre a dimens&#227;o da AE determinada por ecocardiografia&#44; e os n&#237;veis de press&#227;o arterial sist&#243;lica e de press&#227;o de pulso &#40;PP&#41;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">13</span></a>&#46; Por outro lado&#44; na hipertens&#227;o arterial existe evid&#234;ncia de uma rela&#231;&#227;o entre a PP e o aumento da incid&#234;ncia de FA<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">14</span></a>&#46; A PP tem&#8208;se revelado superior &#224; press&#227;o arterial m&#233;dia &#40;PAM&#41; ou &#224; distensibilidade a&#243;rtica como preditor de risco de FA<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">15&#44;16</span></a>&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Existe uma boa correla&#231;&#227;o entre a dura&#231;&#227;o da onda P obtida a partir de uma deriva&#231;&#227;o eletrocardiogr&#225;fica de superf&#237;cie e a dura&#231;&#227;o m&#225;xima dos eletrogramas da aur&#237;cula&#46; A dura&#231;&#227;o da onda P correlaciona&#8208;se com os tempos de condu&#231;&#227;o interauricular e intra&#8208;auricular<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">A dispers&#227;o da onda P &#40;Pd&#41;&#44; que corresponde &#224; diferen&#231;a entre a dura&#231;&#227;o da onda P m&#225;xima e m&#237;nima&#44; registada a partir de m&#250;ltiplas deriva&#231;&#245;es em ritmo sinusal&#44; tem sido estudada como m&#233;todo de avaliar o risco de FA em popula&#231;&#245;es sem doen&#231;a cardiovascular e numa diversidade de patologias&#44; que v&#227;o da hipertens&#227;o arterial &#224; cardiopatia isqu&#233;mica&#44; &#224; cardiopatia valvular&#44; &#224;s cardiopatias cong&#233;nitas e &#224; insufici&#234;ncia card&#237;aca&#44; entre outras<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Em doentes hipertensos&#44; a Pd pode ajudar a identificar situa&#231;&#245;es de hipertrofia ventricular esquerda ou de disfun&#231;&#227;o diast&#243;lica ventricular esquerda&#44; que condicionam altera&#231;&#245;es morfol&#243;gicas e hemodin&#226;micas na AE&#44; aumentando o risco de FA&#46; O aumento das press&#245;es intra&#8208;auriculares e a eventual isquemia favorecem a remodelagem auricular com desorganiza&#231;&#227;o das fibras mioc&#225;rdicas e fibrose&#44; dilata&#231;&#227;o e instabilidade el&#233;trica<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">17&#44;18</span></a>&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Outros fatores favorecedores do aumento da Pd e da fibrose auricular s&#227;o a ativa&#231;&#227;o da angiotensina II e das catecolaminas<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">18</span></a>&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Em doentes hipertensos&#44; a interven&#231;&#227;o terap&#234;utica sobre o sistema renina&#8208;angiotensina&#8208;aldosterona &#40;SRAA&#41; com o perindopril permitiu documentar diminui&#231;&#227;o da Pd<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46; Outro estudo&#44; envolvendo o SRAA com o uso do quinapril&#44; mostrou o mesmo benef&#237;cio<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">O aumento da Pd e da dura&#231;&#227;o m&#225;xima da onda P exprimem instabilidade e heterogeneidade da condu&#231;&#227;o auricular&#44; que pode ser consequ&#234;ncia das altera&#231;&#245;es morfol&#243;gicas e hemodin&#226;micas a que &#233; submetida a AE como consequ&#234;ncia da hipertens&#227;o arterial<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">18</span></a>&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">A insufici&#234;ncia card&#237;aca com fra&#231;&#227;o de eje&#231;&#227;o reduzida predisp&#245;e para a instala&#231;&#227;o de FA&#46; Num estudo efetuado em doentes com miocardiopatia dilatada n&#227;o isqu&#233;mica&#44; a Pd era muito mais elevada do que no grupo controlo<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">19</span></a>&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">A varia&#231;&#227;o hemodin&#226;mica gerada pela disfun&#231;&#227;o ventricular esquerda e a ativa&#231;&#227;o neuro&#8208;hormonal relacionada&#44; com consequente repercuss&#227;o ao n&#237;vel auricular esquerdo&#44; permitem explicar o aumento da Pd&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Analisando a Pd no estudo de Camsari et al&#46; em doentes com insufici&#234;ncia card&#237;aca<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">20</span></a>&#44; observou&#8208;se uma correla&#231;&#227;o significativa com a fra&#231;&#227;o de eje&#231;&#227;o ventricular esquerda&#46; Nestas situa&#231;&#245;es&#44; existe reconhecidamente uma estimula&#231;&#227;o da atividade simp&#225;tica e do SRAA&#44; fatores que influenciam a dura&#231;&#227;o da onda P e a Pd&#46; O tratamento com o metoprolol&#44; no referido estudo&#44; permitiu reduzir tanto a dura&#231;&#227;o m&#225;xima&#44; como a Pd<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">20</span></a>&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">A ressincroniza&#231;&#227;o card&#237;aca &#40;CRT&#41; em doentes sintom&#225;ticos&#44; apesar da terap&#234;utica farmacol&#243;gica otimizada&#44; em ritmo sinusal&#44; com FEj<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>35&#37;&#44; dura&#231;&#227;o do QRS<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>130<span class="elsevierStyleHsp" style=""></span>mseg&#44; e bloqueio completo do ramo esquerdo&#44; permite melhorar a fun&#231;&#227;o ventricular esquerda e reduzir a ativa&#231;&#227;o neuro&#8208;humoral&#46; Existe tamb&#233;m demonstra&#231;&#227;o de contribuir para a remodelagem reversa auricular e&#44; assim&#44; para a melhoria da fun&#231;&#227;o auricular<a class="elsevierStyleCrossRefs" href="#bib0235"><span class="elsevierStyleSup">21&#44;22</span></a>&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Num estudo efetuado em 46 doentes com insufici&#234;ncia card&#237;aca com fra&#231;&#227;o de eje&#231;&#227;o reduzida submetidos a CRT&#44; a avalia&#231;&#227;o aos tr&#234;s meses permitiu observar diminui&#231;&#227;o da dura&#231;&#227;o m&#225;xima da onda P e da Pd&#44; redu&#231;&#227;o do di&#226;metro da AE e melhoria da fra&#231;&#227;o de eje&#231;&#227;o ventricular esquerda<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">22</span></a>&#46; Existia uma correla&#231;&#227;o positiva entre a dura&#231;&#227;o m&#225;xima da onda P&#44; a Pd e a redu&#231;&#227;o do di&#226;metro da AE e uma correla&#231;&#227;o negativa com a melhoria da fra&#231;&#227;o de eje&#231;&#227;o ventricular esquerda&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">A for&#231;a terminal da onda P em V1 &#40;PTFV1&#41; &#233; o resultado do produto da amplitude do componente negativo terminal da onda P em V1 pela dura&#231;&#227;o em ms&#46; &#201; um marcador com valor progn&#243;stico cardiovascular e existe evid&#234;ncia de traduzir aumento do risco de FA<a class="elsevierStyleCrossRefs" href="#bib0245"><span class="elsevierStyleSup">23&#44;24</span></a>&#46; Um valor negativo da PTFV1<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>40mm<span class="elsevierStyleHsp" style=""></span>x<span class="elsevierStyleHsp" style=""></span>ms mostrou&#44; em doentes com hist&#243;ria de enfarte do mioc&#225;rdio&#44; ser preditor de mortalidade card&#237;aca ou hospitaliza&#231;&#227;o por insufici&#234;ncia card&#237;aca<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">23</span></a>&#46; Em outro estudo&#44; em doentes com massa ventricular esquerda aumentada&#44; a PTFV1<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>40<span class="elsevierStyleHsp" style=""></span>mm<span class="elsevierStyleHsp" style=""></span>x<span class="elsevierStyleHsp" style=""></span>ms estava associada com risco de AVC isqu&#233;mico<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">25</span></a>&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">&#199;imen et al&#46; abordaram&#44; em doentes com hipertens&#227;o arterial essencial&#44; sem evid&#234;ncia de altera&#231;&#245;es card&#237;acas estruturais significativas e com eleva&#231;&#227;o da PP &#40;&#8805;<span class="elsevierStyleHsp" style=""></span>60<span class="elsevierStyleHsp" style=""></span>mmHg&#41;&#44; as altera&#231;&#245;es precoces do tempo de condu&#231;&#227;o auricular e a Pd<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">26</span></a>&#46; O atraso eletromec&#226;nico auricular &#40;AEMD&#41; foi avaliado por ecocardiografia&#47;Doppler tecidual&#46; A Pd foi avaliada por eletrocardiograma&#46; Os autores mostraram que&#44; nesta popula&#231;&#227;o de 157 doentes&#44; a PP elevada estava associada com AEMD e com aumento da Pd&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">A dete&#231;&#227;o&#44; por meios n&#227;o invasivos de f&#225;cil acesso&#44; de altera&#231;&#245;es precoces que possam permitir a preven&#231;&#227;o da remodelagem estrutural e el&#233;trica e&#44; em &#250;ltima an&#225;lise&#44; reduzir o risco de FA &#233; da maior relev&#226;ncia e o estudo de &#199;imen et al&#46;&#44; publicado neste n&#250;mero da Revista Portuguesa de Cardiologia&#44; &#233; mais um contributo&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflito de interesses</span><p id="par0105" class="elsevierStylePara elsevierViewall">O autor declara n&#227;o haver conflito de interesses&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflito de interesses"
        ]
        1 => array:1 [
          "titulo" => "Bibliografia"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:26 [
            0 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Early changes in atrial electromechanical coupling in patients with hypertension&#58; assessment by tissue Doppler imaging"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46;K&#46; Avci"
                            1 => "O&#46; Gulmez"
                            2 => "Donmez Guclu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/0366-6999.182846"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chin Med J &#40;Engl&#41;&#46;"
                        "fecha" => "2016 Jun 5"
                        "volumen" => "129"
                        "paginaInicial" => "1311"
                        "paginaFinal" => "1315"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27231168"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Alterations of cardiac structure in patients with isolated office&#44; ambulatory&#44; or home hypertension&#58; Data from the general population &#40;Pressione Arteriose Monitorate E Loro Associazioni &#91;PAMELA&#93; Study&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "R&#46; Sega"
                            1 => "G&#46; Trocino"
                            2 => "A&#46; Lanzarotti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation&#46;"
                        "fecha" => "2001"
                        "volumen" => "104"
                        "paginaInicial" => "1385"
                        "paginaFinal" => "1392"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11560854"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atrial tissue Doppler imaging for prediction of new&#8208;onset atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46;B&#46; De Vos"
                            1 => "B&#46; Weijs"
                            2 => "H&#46;J&#46; Crijns"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/hrt.2008.148528"
                      "Revista" => array:6 [
                        "tituloSerie" => "Heart&#46;"
                        "fecha" => "2009"
                        "volumen" => "95"
                        "paginaInicial" => "835"
                        "paginaFinal" => "840"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19074923"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atrial fibrillation as an independent risk factor for stroke&#58; the Framingham Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;A&#46; Wolf"
                            1 => "R&#46;D&#46; Abbott"
                            2 => "W&#46;B&#46; Kannel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "1991"
                        "volumen" => "22"
                        "paginaInicial" => "983"
                        "paginaFinal" => "988"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1866765"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The epidemiology of atrial fibrillation in elderly persons&#58; the tip of the iceberg"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;S&#46; Go"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Geriatr Cardiol&#46;"
                        "fecha" => "2005"
                        "volumen" => "14"
                        "paginaInicial" => "56"
                        "paginaFinal" => "61"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15785146"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of atrial fibrillation on the risk of death&#58; the Framingham Heart Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "E&#46;J&#46; Benjamin"
                            1 => "P&#46;A&#46; Wolf"
                            2 => "R&#46;B&#46; d&#8217;Agostino"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation&#46;"
                        "fecha" => "1998"
                        "volumen" => "98"
                        "paginaInicial" => "946"
                        "paginaFinal" => "952"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9737513"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of atrial electromechanical coupling and influential factors in nonrheumatic paroxysmal atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "Q&#46;Q&#46; Cui"
                            1 => "W&#46; Zhang"
                            2 => "H&#46; Wang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/clc.20162"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Cardiol&#46;"
                        "fecha" => "2008"
                        "volumen" => "31"
                        "paginaInicial" => "74"
                        "paginaFinal" => "78"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18257022"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Doppler tissue analysis of atrial electromechanical coupling in paroxysmal atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "W&#46; Omi"
                            1 => "H&#46; Nagai"
                            2 => "M&#46; Takamura"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.echo.2004.08.029"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Soc Echocardiogr&#46;"
                        "fecha" => "2005"
                        "volumen" => "18"
                        "paginaInicial" => "39"
                        "paginaFinal" => "44"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15637487"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of atrial conduction time by P wave dispersion and tissue Doppler echocardiography in prehypertensive patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46; Ermis"
                            1 => "N&#46; A&#231;ikg&#246;z"
                            2 => "E&#46; Yasar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Turk Kardiyol Dern Ars&#46;"
                        "fecha" => "2010"
                        "volumen" => "38"
                        "paginaInicial" => "525"
                        "paginaFinal" => "530"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21248451"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Regression of electrocardiographic left ventricular hypertrophy decreased incidence of new&#8208;onset atrial fibrillation in patients with hypertension"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "P&#46;M&#46; Okin"
                            1 => "K&#46; Wachtell"
                            2 => "R&#46;B&#46; Devereux"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jama.296.10.1242"
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA&#46;"
                        "fecha" => "2006"
                        "volumen" => "296"
                        "paginaInicial" => "1242"
                        "paginaFinal" => "1248"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16968848"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The left atrium&#44; atrial fibrillation&#44; and the risk of stroke in hypertensive patients with left ventricular hypertrophy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "K&#46; Wachtell"
                            1 => "R&#46;B&#46; Devereux"
                            2 => "P&#46;A&#46; Lyle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1177/1753944708093846"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ther Adv Cardiovasc Dis&#46;"
                        "fecha" => "2008"
                        "volumen" => "2"
                        "paginaInicial" => "507"
                        "paginaFinal" => "513"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19124445"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of paroxysmal atrial fibrillation depending on the regression of left ventricular hypertrophy in arterial hypertension"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46;G&#46; Hennersdorf"
                            1 => "P&#46;O&#46; Schueller"
                            2 => "S&#46; Steiner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1291/hypres.30.535"
                      "Revista" => array:6 [
                        "tituloSerie" => "Hypertens Res&#46;"
                        "fecha" => "2007"
                        "volumen" => "30"
                        "paginaInicial" => "535"
                        "paginaFinal" => "540"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17664857"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Influence of blood pressure on left atrial size&#46; The Framingham Heart Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46;M&#46; Vaziri"
                            1 => "M&#46;G&#46; Larson"
                            2 => "M&#46;S&#46; Lauer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hypertension&#46;"
                        "fecha" => "1995"
                        "volumen" => "25"
                        "paginaInicial" => "1155"
                        "paginaFinal" => "1160"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7768556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association of pulse pressure with new&#8208;onset atrial fibrillation in patients with hypertension and left ventricular hypertrophy&#58; the Losartan Intervention For Endpoint &#40;LIFE&#41; reduction in hypertension study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;C&#46;K&#46; Larstorp"
                            1 => "I&#46; Ariansen"
                            2 => "K&#46; Gjesdal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/HYPERTENSIONAHA.112.195032"
                      "Revista" => array:6 [
                        "tituloSerie" => "Hypertension&#46;"
                        "fecha" => "2012"
                        "volumen" => "60"
                        "paginaInicial" => "347"
                        "paginaFinal" => "353"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22753219"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulse pressure risk of new&#8208;onset atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46;F&#46; Mitchell"
                            1 => "R&#46;S&#46; Vasan"
                            2 => "M&#46;J&#46; Keyes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jama.297.7.709"
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA&#46;"
                        "fecha" => "2007"
                        "volumen" => "297"
                        "paginaInicial" => "709"
                        "paginaFinal" => "715"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17312290"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Relation of systolic&#44; diastolic&#44; and pulse pressures and aortic distensibility with atrial fibrillation &#40;from the Multi&#8208;Ethnic Study of Atherosclerosis&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46;S&#46; Roetker"
                            1 => "L&#46;Y&#46; Chen"
                            2 => "S&#46;R&#46; Heckbert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.amjcard.2014.05.041"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Cardiol&#46;"
                        "fecha" => "2014"
                        "volumen" => "114"
                        "paginaInicial" => "587"
                        "paginaFinal" => "592"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24996553"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "P&#8208;wave dispersion&#58; What we know till now&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Okutucu"
                            1 => "K&#46; Aytemir"
                            2 => "A&#46; Oto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "JRSM Cardiovasc Dis&#46;"
                        "fecha" => "2016"
                        "volumen" => "5"
                        "paginaInicial" => "1"
                        "paginaFinal" => "9"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Are maximum P wave duration and P wave dispersion a marker of target organ damage in the hypertensive population&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46; Dagli"
                            1 => "I&#46; Karaca"
                            2 => "M&#46; Yavuzkir"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00392-007-0587-8"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Res Cardiol&#46;"
                        "fecha" => "2008"
                        "volumen" => "97"
                        "paginaInicial" => "98"
                        "paginaFinal" => "104"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17938849"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "P&#8208;wave duration and P&#8208;wave dispersion in patients with dilated cardiomyopathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "K&#46; Senen"
                            1 => "H&#46; Turhan"
                            2 => "A&#46; Riza Erbay"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ejheart.2003.12.020"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Heart Fail&#46;"
                        "fecha" => "2004"
                        "volumen" => "6"
                        "paginaInicial" => "567"
                        "paginaFinal" => "569"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15302004"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long&#8208;term effects of beta blocker therapy on P&#8208;wave duration and dispersion in congestive heart failure patients&#58; a new effect&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Camsari"
                            1 => "H&#46; Pekdemir"
                            2 => "M&#46;N&#46; Akkus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1054/jelc.2003.50020"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Electrocardiol&#46;"
                        "fecha" => "2003"
                        "volumen" => "36"
                        "paginaInicial" => "111"
                        "paginaFinal" => "116"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12764693"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Improvement of atrial function and atrial reverse remodeling after cardiac resynchronization therapy for heart failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46;M&#46; Yu"
                            1 => "F&#46; Fang"
                            2 => "Q&#46; Zhang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jacc.2007.04.073"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Coll Cardiol&#46;"
                        "fecha" => "2007"
                        "volumen" => "50"
                        "paginaInicial" => "778"
                        "paginaFinal" => "785"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17707183"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Improvement of P wave dispersion after cardiac resynchronization therapy for heart failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46; Ding"
                            1 => "W&#46; Hua"
                            2 => "S&#46; Zhang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jelectrocard.2009.02.005"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Electrocardiol&#46;"
                        "fecha" => "2009"
                        "volumen" => "42"
                        "paginaInicial" => "334"
                        "paginaFinal" => "338"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19539810"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Abnormal P&#8208;wave terminal force in lead V1 is associated with cardiac death or hospitalization for heart failure in prior myocardial infarction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46; Liu"
                            1 => "A&#46; Tamura"
                            2 => "K&#46; Torigoe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00380-012-0307-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Heart Vessels&#46;"
                        "fecha" => "2013"
                        "volumen" => "28"
                        "paginaInicial" => "690"
                        "paginaFinal" => "695"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23160859"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ethnic distribution of ECG predictors of atrial fibrillation and its impact on understanding the ethnic distribution of ischemic stroke in the Atherosclerosis Risk in Communities &#40;ARIC&#41; study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "E&#46;Z&#46; Soliman"
                            1 => "R&#46;J&#46; Prineas"
                            2 => "L&#46;D&#46; Case"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.108.534735"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2009"
                        "volumen" => "40"
                        "paginaInicial" => "1204"
                        "paginaFinal" => "1211"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19213946"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Electrocardiographic left atrial abnormalities and risk of ischemic stroke"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46; Kohsaka"
                            1 => "R&#46;R&#46; Sciacca"
                            2 => "K&#46; Sugioka"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/01.STR.0000185682.09981.26"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2005"
                        "volumen" => "36"
                        "paginaInicial" => "2481"
                        "paginaFinal" => "2483"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16210557"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Early changes in atrial conduction times in hypertensive patients with elevated pulse pressure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46; &#199;imen"
                            1 => "H&#46; Sunman"
                            2 => "T&#46; Han"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Port Cardiol&#46;"
                        "fecha" => "2017"
                        "volumen" => "36"
                        "paginaInicial" => "453"
                        "paginaFinal" => "459"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/08702551/0000003600000006/v2_201706240150/S0870255117303487/v2_201706240150/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "29261"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Artigos Originais"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08702551/0000003600000006/v2_201706240150/S0870255117303487/v2_201706240150/pt/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117303487?idApp=UINPBA00004E"
]
Partilhar
Informação da revista

Estatísticas

Siga este link para acessar o texto completo do artigo

Comentário Editorial
Predisposição para remodelagem auricular na hipertensão arterial - deteção precoce por meios não invasivos
Early detection by non‐invasive methods of predisposition to atrial remodeling in hypertension
Luiz Menezes Falcão
Faculdade de Medicina de Lisboa. Hospital de Santa Maria/Centro Hospitalar Lisboa Norte, Lisboa, Portugal
Lido
15439
Vezes
que se leu este artigo
2058
Total PDF
13381
Total HTML
Compartilhar estatísticas
 array:26 [
  "pii" => "S0870255117303487"
  "issn" => "08702551"
  "doi" => "10.1016/j.repc.2017.05.002"
  "estado" => "S300"
  "fechaPublicacion" => "2017-06-01"
  "aid" => "1006"
  "copyright" => "Sociedade Portuguesa de Cardiologia"
  "copyrightAnyo" => "2017"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "dis"
  "cita" => "Rev Port Cardiol. 2017;36:461-3"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2989
    "formatos" => array:3 [
      "EPUB" => 166
      "HTML" => 2364
      "PDF" => 459
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:20 [
      "pii" => "S2174204917301307"
      "issn" => "21742049"
      "doi" => "10.1016/j.repce.2017.05.002"
      "estado" => "S300"
      "fechaPublicacion" => "2017-06-01"
      "aid" => "1006"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "dis"
      "cita" => "Rev Port Cardiol. 2017;36:461-3"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 2502
        "formatos" => array:3 [
          "EPUB" => 153
          "HTML" => 1998
          "PDF" => 351
        ]
      ]
      "en" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Editorial comment</span>"
        "titulo" => "Early detection by non-invasive methods of predisposition to atrial remodeling in hypertension"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "461"
            "paginaFinal" => "463"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Predisposi&#231;&#227;o para remodelagem auricular na hipertens&#227;o arterial - dete&#231;&#227;o precoce por meios n&#227;o invasivos"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Luiz Menezes Falc&#227;o"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "Luiz"
                "apellidos" => "Menezes Falc&#227;o"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "pt" => array:9 [
          "pii" => "S0870255117303487"
          "doi" => "10.1016/j.repc.2017.05.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "pt"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117303487?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917301307?idApp=UINPBA00004E"
      "url" => "/21742049/0000003600000006/v1_201707020042/S2174204917301307/v1_201707020042/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S0870255116302323"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2016.11.009"
    "estado" => "S300"
    "fechaPublicacion" => "2017-06-01"
    "aid" => "1015"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Cardiol. 2017;36:465-72"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2629
      "formatos" => array:3 [
        "EPUB" => 183
        "HTML" => 1912
        "PDF" => 534
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review Article</span>"
      "titulo" => "Mid-regional pro-adrenomedullin and ST2 in heart failure&#58; Contributions to diagnosis and prognosis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "465"
          "paginaFinal" => "472"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "A MR-proadrenomedulina e o ST2 na insufici&#234;ncia card&#237;aca&#58; contribui&#231;&#227;o para o diagn&#243;stico e progn&#243;stico"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1016
              "Ancho" => 2333
              "Tamanyo" => 68545
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Schematic representation of the interleukin-33 &#40;IL-33&#41;&#47;ST2 pathway&#46; IL-33 exerts its biological actions when it binds to the ST2L isoform&#46; In situations of myocardial stress&#44; the IL-33&#47;ST2L interaction appears to have a cardioprotective effect&#46; Soluble ST2 acts as a decoy receptor&#44; preventing the beneficial effects of IL-33&#47;ST2L signaling&#46; IL-33&#58; interleukin-33&#59; sST2&#58; soluble ST2&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Daniela Lopes, Luiz Menezes Falc&#227;o"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Daniela"
              "apellidos" => "Lopes"
            ]
            1 => array:2 [
              "nombre" => "Luiz"
              "apellidos" => "Menezes Falc&#227;o"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2174204917301745"
        "doi" => "10.1016/j.repce.2016.11.012"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917301745?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116302323?idApp=UINPBA00004E"
    "url" => "/08702551/0000003600000006/v2_201706240150/S0870255116302323/v2_201706240150/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S0870255117303475"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2016.10.012"
    "estado" => "S300"
    "fechaPublicacion" => "2017-06-01"
    "aid" => "1005"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Cardiol. 2017;36:453-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3082
      "formatos" => array:3 [
        "EPUB" => 178
        "HTML" => 2486
        "PDF" => 418
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Early changes in atrial conduction times in hypertensive patients with elevated pulse pressure"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "453"
          "paginaFinal" => "459"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Altera&#231;&#245;es precoces nos tempos de condu&#231;&#227;o auricular nos doentes hipertensos com press&#227;o de pulso elevada"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 883
              "Ancho" => 3332
              "Tamanyo" => 198713
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Pearson&#39;s correlation analysis demonstrating the correlation between pulse pressure and atrial electromechanical delay&#46; EMD&#58; electromechanical delay&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Tolga &#199;imen, Hamza Sunman, Tolga Han Efe, Ahmet Akyel, Kadriye Yayla, Haluk Furkan &#350;ahan, Murat Bilgin, Lale Din&#231; Asarc&#305;kl&#305;, Ali Nallbani, Mehmet Do&#287;an, Sad&#305;k A&#231;&#305;kel, Ekrem Yeter"
          "autores" => array:12 [
            0 => array:2 [
              "nombre" => "Tolga"
              "apellidos" => "&#199;imen"
            ]
            1 => array:2 [
              "nombre" => "Hamza"
              "apellidos" => "Sunman"
            ]
            2 => array:2 [
              "nombre" => "Tolga Han"
              "apellidos" => "Efe"
            ]
            3 => array:2 [
              "nombre" => "Ahmet"
              "apellidos" => "Akyel"
            ]
            4 => array:2 [
              "nombre" => "Kadriye"
              "apellidos" => "Yayla"
            ]
            5 => array:2 [
              "nombre" => "Haluk Furkan"
              "apellidos" => "&#350;ahan"
            ]
            6 => array:2 [
              "nombre" => "Murat"
              "apellidos" => "Bilgin"
            ]
            7 => array:2 [
              "nombre" => "Lale Din&#231;"
              "apellidos" => "Asarc&#305;kl&#305;"
            ]
            8 => array:2 [
              "nombre" => "Ali"
              "apellidos" => "Nallbani"
            ]
            9 => array:2 [
              "nombre" => "Mehmet"
              "apellidos" => "Do&#287;an"
            ]
            10 => array:2 [
              "nombre" => "Sad&#305;k"
              "apellidos" => "A&#231;&#305;kel"
            ]
            11 => array:2 [
              "nombre" => "Ekrem"
              "apellidos" => "Yeter"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2174204917301733"
        "doi" => "10.1016/j.repce.2016.10.022"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917301733?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117303475?idApp=UINPBA00004E"
    "url" => "/08702551/0000003600000006/v2_201706240150/S0870255117303475/v2_201706240150/en/main.assets"
  ]
  "asociados" => array:1 [
    0 => array:20 [
      "pii" => "S0870255117303475"
      "issn" => "08702551"
      "doi" => "10.1016/j.repc.2016.10.012"
      "estado" => "S300"
      "fechaPublicacion" => "2017-06-01"
      "aid" => "1005"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Rev Port Cardiol. 2017;36:453-9"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 3082
        "formatos" => array:3 [
          "EPUB" => 178
          "HTML" => 2486
          "PDF" => 418
        ]
      ]
      "en" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
        "titulo" => "Early changes in atrial conduction times in hypertensive patients with elevated pulse pressure"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "tieneResumen" => array:2 [
          0 => "en"
          1 => "pt"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "453"
            "paginaFinal" => "459"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Altera&#231;&#245;es precoces nos tempos de condu&#231;&#227;o auricular nos doentes hipertensos com press&#227;o de pulso elevada"
          ]
        ]
        "contieneResumen" => array:2 [
          "en" => true
          "pt" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figure 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 883
                "Ancho" => 3332
                "Tamanyo" => 198713
              ]
            ]
            "descripcion" => array:1 [
              "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Pearson&#39;s correlation analysis demonstrating the correlation between pulse pressure and atrial electromechanical delay&#46; EMD&#58; electromechanical delay&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Tolga &#199;imen, Hamza Sunman, Tolga Han Efe, Ahmet Akyel, Kadriye Yayla, Haluk Furkan &#350;ahan, Murat Bilgin, Lale Din&#231; Asarc&#305;kl&#305;, Ali Nallbani, Mehmet Do&#287;an, Sad&#305;k A&#231;&#305;kel, Ekrem Yeter"
            "autores" => array:12 [
              0 => array:2 [
                "nombre" => "Tolga"
                "apellidos" => "&#199;imen"
              ]
              1 => array:2 [
                "nombre" => "Hamza"
                "apellidos" => "Sunman"
              ]
              2 => array:2 [
                "nombre" => "Tolga Han"
                "apellidos" => "Efe"
              ]
              3 => array:2 [
                "nombre" => "Ahmet"
                "apellidos" => "Akyel"
              ]
              4 => array:2 [
                "nombre" => "Kadriye"
                "apellidos" => "Yayla"
              ]
              5 => array:2 [
                "nombre" => "Haluk Furkan"
                "apellidos" => "&#350;ahan"
              ]
              6 => array:2 [
                "nombre" => "Murat"
                "apellidos" => "Bilgin"
              ]
              7 => array:2 [
                "nombre" => "Lale Din&#231;"
                "apellidos" => "Asarc&#305;kl&#305;"
              ]
              8 => array:2 [
                "nombre" => "Ali"
                "apellidos" => "Nallbani"
              ]
              9 => array:2 [
                "nombre" => "Mehmet"
                "apellidos" => "Do&#287;an"
              ]
              10 => array:2 [
                "nombre" => "Sad&#305;k"
                "apellidos" => "A&#231;&#305;kel"
              ]
              11 => array:2 [
                "nombre" => "Ekrem"
                "apellidos" => "Yeter"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2174204917301733"
          "doi" => "10.1016/j.repce.2016.10.022"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917301733?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117303475?idApp=UINPBA00004E"
      "url" => "/08702551/0000003600000006/v2_201706240150/S0870255117303475/v2_201706240150/en/main.assets"
    ]
  ]
  "pt" => array:12 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Coment&#225;rio Editorial</span>"
    "titulo" => "Predisposi&#231;&#227;o para remodelagem auricular na hipertens&#227;o arterial - dete&#231;&#227;o precoce por meios n&#227;o invasivos"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "461"
        "paginaFinal" => "463"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Luiz Menezes Falc&#227;o"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "Luiz"
            "apellidos" => "Menezes Falc&#227;o"
            "email" => array:1 [
              0 => "luizmfalcao&#64;sapo&#46;pt"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Faculdade de Medicina de Lisboa&#46; Hospital de Santa Maria&#47;Centro Hospitalar Lisboa Norte&#44; Lisboa&#44; Portugal"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Early detection by non&#8208;invasive methods of predisposition to atrial remodeling in hypertension"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Hipertens&#227;o arterial com valores tensionais persistentemente elevados &#233; um dos principais fatores de risco cardiovascular&#46; A hipertens&#227;o arterial &#233; respons&#225;vel por uma sobrecarga de press&#227;o que favorece a remodelagem auricular ocasionando altera&#231;&#245;es estruturais e el&#233;tricas<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1&#44;2</span></a>&#46; As consequ&#234;ncias fazem&#8208;se sentir a v&#225;rios n&#237;veis e&#44; nomeadamente&#44; no aumento do risco de instala&#231;&#227;o de fibrilha&#231;&#227;o auricular &#40;FA&#41; que se agrava com o avan&#231;ar da idade<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">3</span></a>&#46; Como est&#225; bem estabelecido&#44; a FA tem importante repercuss&#227;o ao n&#237;vel do d&#233;bito card&#237;aco e associa&#8208;se a um risco quatro a cinco vezes superior de acidente vascular cerebral &#40;AVC&#41; isqu&#233;mico cardioemb&#243;lico<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">4&#44;5</span></a>&#46; Tamb&#233;m o risco de mortalidade fica muito acrescido pela presen&#231;a desta entidade<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">6</span></a>&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">O atraso eletromec&#226;nico interauricular e o prolongamento do tempo de ativa&#231;&#227;o auricular total t&#234;m sido ligados ao aumento da incid&#234;ncia de FA<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">3&#44;7&#44;8</span></a>&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">O prolongamento do tempo de condu&#231;&#227;o auricular fornece indica&#231;&#227;o de remodelagem estrutural e el&#233;trica&#44; tendo assim vantagem sobre a medi&#231;&#227;o da dimens&#227;o da aur&#237;cula esquerda &#40;AE&#41; ou do &#237;ndice do volume da AE<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1&#44;9</span></a>&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">O &#237;ndice de massa ventricular esquerdo &#40;IMVE&#41; est&#225; associado com um prolongamento do tempo interauricular e com o tempo de acoplamento auricular esquerdo<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">1</span></a>&#46; A gravidade da hipertrofia ventricular esquerda parece estar associada&#44; entre outros fatores&#44; com a instala&#231;&#227;o de FA&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Existe demonstra&#231;&#227;o de que a terap&#234;utica farmacol&#243;gica&#44; com a redu&#231;&#227;o da press&#227;o arterial &#40;PA&#41; e consequente redu&#231;&#227;o da massa ventricular esquerda&#44; pode permitir reduzir o aparecimento da FA<a class="elsevierStyleCrossRefs" href="#bib0180"><span class="elsevierStyleSup">10&#8211;12</span></a>&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Dados do <span class="elsevierStyleItalic">Framingham Heart Study</span> j&#225; tinham evidenciado haver uma rela&#231;&#227;o entre a dimens&#227;o da AE determinada por ecocardiografia&#44; e os n&#237;veis de press&#227;o arterial sist&#243;lica e de press&#227;o de pulso &#40;PP&#41;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">13</span></a>&#46; Por outro lado&#44; na hipertens&#227;o arterial existe evid&#234;ncia de uma rela&#231;&#227;o entre a PP e o aumento da incid&#234;ncia de FA<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">14</span></a>&#46; A PP tem&#8208;se revelado superior &#224; press&#227;o arterial m&#233;dia &#40;PAM&#41; ou &#224; distensibilidade a&#243;rtica como preditor de risco de FA<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">15&#44;16</span></a>&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Existe uma boa correla&#231;&#227;o entre a dura&#231;&#227;o da onda P obtida a partir de uma deriva&#231;&#227;o eletrocardiogr&#225;fica de superf&#237;cie e a dura&#231;&#227;o m&#225;xima dos eletrogramas da aur&#237;cula&#46; A dura&#231;&#227;o da onda P correlaciona&#8208;se com os tempos de condu&#231;&#227;o interauricular e intra&#8208;auricular<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">A dispers&#227;o da onda P &#40;Pd&#41;&#44; que corresponde &#224; diferen&#231;a entre a dura&#231;&#227;o da onda P m&#225;xima e m&#237;nima&#44; registada a partir de m&#250;ltiplas deriva&#231;&#245;es em ritmo sinusal&#44; tem sido estudada como m&#233;todo de avaliar o risco de FA em popula&#231;&#245;es sem doen&#231;a cardiovascular e numa diversidade de patologias&#44; que v&#227;o da hipertens&#227;o arterial &#224; cardiopatia isqu&#233;mica&#44; &#224; cardiopatia valvular&#44; &#224;s cardiopatias cong&#233;nitas e &#224; insufici&#234;ncia card&#237;aca&#44; entre outras<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Em doentes hipertensos&#44; a Pd pode ajudar a identificar situa&#231;&#245;es de hipertrofia ventricular esquerda ou de disfun&#231;&#227;o diast&#243;lica ventricular esquerda&#44; que condicionam altera&#231;&#245;es morfol&#243;gicas e hemodin&#226;micas na AE&#44; aumentando o risco de FA&#46; O aumento das press&#245;es intra&#8208;auriculares e a eventual isquemia favorecem a remodelagem auricular com desorganiza&#231;&#227;o das fibras mioc&#225;rdicas e fibrose&#44; dilata&#231;&#227;o e instabilidade el&#233;trica<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">17&#44;18</span></a>&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Outros fatores favorecedores do aumento da Pd e da fibrose auricular s&#227;o a ativa&#231;&#227;o da angiotensina II e das catecolaminas<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">18</span></a>&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Em doentes hipertensos&#44; a interven&#231;&#227;o terap&#234;utica sobre o sistema renina&#8208;angiotensina&#8208;aldosterona &#40;SRAA&#41; com o perindopril permitiu documentar diminui&#231;&#227;o da Pd<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46; Outro estudo&#44; envolvendo o SRAA com o uso do quinapril&#44; mostrou o mesmo benef&#237;cio<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">O aumento da Pd e da dura&#231;&#227;o m&#225;xima da onda P exprimem instabilidade e heterogeneidade da condu&#231;&#227;o auricular&#44; que pode ser consequ&#234;ncia das altera&#231;&#245;es morfol&#243;gicas e hemodin&#226;micas a que &#233; submetida a AE como consequ&#234;ncia da hipertens&#227;o arterial<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">18</span></a>&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">A insufici&#234;ncia card&#237;aca com fra&#231;&#227;o de eje&#231;&#227;o reduzida predisp&#245;e para a instala&#231;&#227;o de FA&#46; Num estudo efetuado em doentes com miocardiopatia dilatada n&#227;o isqu&#233;mica&#44; a Pd era muito mais elevada do que no grupo controlo<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">19</span></a>&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">A varia&#231;&#227;o hemodin&#226;mica gerada pela disfun&#231;&#227;o ventricular esquerda e a ativa&#231;&#227;o neuro&#8208;hormonal relacionada&#44; com consequente repercuss&#227;o ao n&#237;vel auricular esquerdo&#44; permitem explicar o aumento da Pd&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Analisando a Pd no estudo de Camsari et al&#46; em doentes com insufici&#234;ncia card&#237;aca<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">20</span></a>&#44; observou&#8208;se uma correla&#231;&#227;o significativa com a fra&#231;&#227;o de eje&#231;&#227;o ventricular esquerda&#46; Nestas situa&#231;&#245;es&#44; existe reconhecidamente uma estimula&#231;&#227;o da atividade simp&#225;tica e do SRAA&#44; fatores que influenciam a dura&#231;&#227;o da onda P e a Pd&#46; O tratamento com o metoprolol&#44; no referido estudo&#44; permitiu reduzir tanto a dura&#231;&#227;o m&#225;xima&#44; como a Pd<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">20</span></a>&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">A ressincroniza&#231;&#227;o card&#237;aca &#40;CRT&#41; em doentes sintom&#225;ticos&#44; apesar da terap&#234;utica farmacol&#243;gica otimizada&#44; em ritmo sinusal&#44; com FEj<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>35&#37;&#44; dura&#231;&#227;o do QRS<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>130<span class="elsevierStyleHsp" style=""></span>mseg&#44; e bloqueio completo do ramo esquerdo&#44; permite melhorar a fun&#231;&#227;o ventricular esquerda e reduzir a ativa&#231;&#227;o neuro&#8208;humoral&#46; Existe tamb&#233;m demonstra&#231;&#227;o de contribuir para a remodelagem reversa auricular e&#44; assim&#44; para a melhoria da fun&#231;&#227;o auricular<a class="elsevierStyleCrossRefs" href="#bib0235"><span class="elsevierStyleSup">21&#44;22</span></a>&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Num estudo efetuado em 46 doentes com insufici&#234;ncia card&#237;aca com fra&#231;&#227;o de eje&#231;&#227;o reduzida submetidos a CRT&#44; a avalia&#231;&#227;o aos tr&#234;s meses permitiu observar diminui&#231;&#227;o da dura&#231;&#227;o m&#225;xima da onda P e da Pd&#44; redu&#231;&#227;o do di&#226;metro da AE e melhoria da fra&#231;&#227;o de eje&#231;&#227;o ventricular esquerda<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">22</span></a>&#46; Existia uma correla&#231;&#227;o positiva entre a dura&#231;&#227;o m&#225;xima da onda P&#44; a Pd e a redu&#231;&#227;o do di&#226;metro da AE e uma correla&#231;&#227;o negativa com a melhoria da fra&#231;&#227;o de eje&#231;&#227;o ventricular esquerda&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">A for&#231;a terminal da onda P em V1 &#40;PTFV1&#41; &#233; o resultado do produto da amplitude do componente negativo terminal da onda P em V1 pela dura&#231;&#227;o em ms&#46; &#201; um marcador com valor progn&#243;stico cardiovascular e existe evid&#234;ncia de traduzir aumento do risco de FA<a class="elsevierStyleCrossRefs" href="#bib0245"><span class="elsevierStyleSup">23&#44;24</span></a>&#46; Um valor negativo da PTFV1<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>40mm<span class="elsevierStyleHsp" style=""></span>x<span class="elsevierStyleHsp" style=""></span>ms mostrou&#44; em doentes com hist&#243;ria de enfarte do mioc&#225;rdio&#44; ser preditor de mortalidade card&#237;aca ou hospitaliza&#231;&#227;o por insufici&#234;ncia card&#237;aca<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">23</span></a>&#46; Em outro estudo&#44; em doentes com massa ventricular esquerda aumentada&#44; a PTFV1<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>40<span class="elsevierStyleHsp" style=""></span>mm<span class="elsevierStyleHsp" style=""></span>x<span class="elsevierStyleHsp" style=""></span>ms estava associada com risco de AVC isqu&#233;mico<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">25</span></a>&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">&#199;imen et al&#46; abordaram&#44; em doentes com hipertens&#227;o arterial essencial&#44; sem evid&#234;ncia de altera&#231;&#245;es card&#237;acas estruturais significativas e com eleva&#231;&#227;o da PP &#40;&#8805;<span class="elsevierStyleHsp" style=""></span>60<span class="elsevierStyleHsp" style=""></span>mmHg&#41;&#44; as altera&#231;&#245;es precoces do tempo de condu&#231;&#227;o auricular e a Pd<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">26</span></a>&#46; O atraso eletromec&#226;nico auricular &#40;AEMD&#41; foi avaliado por ecocardiografia&#47;Doppler tecidual&#46; A Pd foi avaliada por eletrocardiograma&#46; Os autores mostraram que&#44; nesta popula&#231;&#227;o de 157 doentes&#44; a PP elevada estava associada com AEMD e com aumento da Pd&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">A dete&#231;&#227;o&#44; por meios n&#227;o invasivos de f&#225;cil acesso&#44; de altera&#231;&#245;es precoces que possam permitir a preven&#231;&#227;o da remodelagem estrutural e el&#233;trica e&#44; em &#250;ltima an&#225;lise&#44; reduzir o risco de FA &#233; da maior relev&#226;ncia e o estudo de &#199;imen et al&#46;&#44; publicado neste n&#250;mero da Revista Portuguesa de Cardiologia&#44; &#233; mais um contributo&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflito de interesses</span><p id="par0105" class="elsevierStylePara elsevierViewall">O autor declara n&#227;o haver conflito de interesses&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflito de interesses"
        ]
        1 => array:1 [
          "titulo" => "Bibliografia"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:26 [
            0 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Early changes in atrial electromechanical coupling in patients with hypertension&#58; assessment by tissue Doppler imaging"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46;K&#46; Avci"
                            1 => "O&#46; Gulmez"
                            2 => "Donmez Guclu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/0366-6999.182846"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chin Med J &#40;Engl&#41;&#46;"
                        "fecha" => "2016 Jun 5"
                        "volumen" => "129"
                        "paginaInicial" => "1311"
                        "paginaFinal" => "1315"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27231168"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Alterations of cardiac structure in patients with isolated office&#44; ambulatory&#44; or home hypertension&#58; Data from the general population &#40;Pressione Arteriose Monitorate E Loro Associazioni &#91;PAMELA&#93; Study&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "R&#46; Sega"
                            1 => "G&#46; Trocino"
                            2 => "A&#46; Lanzarotti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation&#46;"
                        "fecha" => "2001"
                        "volumen" => "104"
                        "paginaInicial" => "1385"
                        "paginaFinal" => "1392"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11560854"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atrial tissue Doppler imaging for prediction of new&#8208;onset atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46;B&#46; De Vos"
                            1 => "B&#46; Weijs"
                            2 => "H&#46;J&#46; Crijns"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/hrt.2008.148528"
                      "Revista" => array:6 [
                        "tituloSerie" => "Heart&#46;"
                        "fecha" => "2009"
                        "volumen" => "95"
                        "paginaInicial" => "835"
                        "paginaFinal" => "840"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19074923"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atrial fibrillation as an independent risk factor for stroke&#58; the Framingham Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;A&#46; Wolf"
                            1 => "R&#46;D&#46; Abbott"
                            2 => "W&#46;B&#46; Kannel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "1991"
                        "volumen" => "22"
                        "paginaInicial" => "983"
                        "paginaFinal" => "988"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1866765"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The epidemiology of atrial fibrillation in elderly persons&#58; the tip of the iceberg"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;S&#46; Go"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Geriatr Cardiol&#46;"
                        "fecha" => "2005"
                        "volumen" => "14"
                        "paginaInicial" => "56"
                        "paginaFinal" => "61"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15785146"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of atrial fibrillation on the risk of death&#58; the Framingham Heart Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "E&#46;J&#46; Benjamin"
                            1 => "P&#46;A&#46; Wolf"
                            2 => "R&#46;B&#46; d&#8217;Agostino"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation&#46;"
                        "fecha" => "1998"
                        "volumen" => "98"
                        "paginaInicial" => "946"
                        "paginaFinal" => "952"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9737513"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of atrial electromechanical coupling and influential factors in nonrheumatic paroxysmal atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "Q&#46;Q&#46; Cui"
                            1 => "W&#46; Zhang"
                            2 => "H&#46; Wang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/clc.20162"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Cardiol&#46;"
                        "fecha" => "2008"
                        "volumen" => "31"
                        "paginaInicial" => "74"
                        "paginaFinal" => "78"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18257022"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Doppler tissue analysis of atrial electromechanical coupling in paroxysmal atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "W&#46; Omi"
                            1 => "H&#46; Nagai"
                            2 => "M&#46; Takamura"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.echo.2004.08.029"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Soc Echocardiogr&#46;"
                        "fecha" => "2005"
                        "volumen" => "18"
                        "paginaInicial" => "39"
                        "paginaFinal" => "44"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15637487"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of atrial conduction time by P wave dispersion and tissue Doppler echocardiography in prehypertensive patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46; Ermis"
                            1 => "N&#46; A&#231;ikg&#246;z"
                            2 => "E&#46; Yasar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Turk Kardiyol Dern Ars&#46;"
                        "fecha" => "2010"
                        "volumen" => "38"
                        "paginaInicial" => "525"
                        "paginaFinal" => "530"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21248451"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Regression of electrocardiographic left ventricular hypertrophy decreased incidence of new&#8208;onset atrial fibrillation in patients with hypertension"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "P&#46;M&#46; Okin"
                            1 => "K&#46; Wachtell"
                            2 => "R&#46;B&#46; Devereux"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jama.296.10.1242"
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA&#46;"
                        "fecha" => "2006"
                        "volumen" => "296"
                        "paginaInicial" => "1242"
                        "paginaFinal" => "1248"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16968848"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The left atrium&#44; atrial fibrillation&#44; and the risk of stroke in hypertensive patients with left ventricular hypertrophy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "K&#46; Wachtell"
                            1 => "R&#46;B&#46; Devereux"
                            2 => "P&#46;A&#46; Lyle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1177/1753944708093846"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ther Adv Cardiovasc Dis&#46;"
                        "fecha" => "2008"
                        "volumen" => "2"
                        "paginaInicial" => "507"
                        "paginaFinal" => "513"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19124445"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of paroxysmal atrial fibrillation depending on the regression of left ventricular hypertrophy in arterial hypertension"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46;G&#46; Hennersdorf"
                            1 => "P&#46;O&#46; Schueller"
                            2 => "S&#46; Steiner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1291/hypres.30.535"
                      "Revista" => array:6 [
                        "tituloSerie" => "Hypertens Res&#46;"
                        "fecha" => "2007"
                        "volumen" => "30"
                        "paginaInicial" => "535"
                        "paginaFinal" => "540"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17664857"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Influence of blood pressure on left atrial size&#46; The Framingham Heart Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46;M&#46; Vaziri"
                            1 => "M&#46;G&#46; Larson"
                            2 => "M&#46;S&#46; Lauer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hypertension&#46;"
                        "fecha" => "1995"
                        "volumen" => "25"
                        "paginaInicial" => "1155"
                        "paginaFinal" => "1160"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7768556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association of pulse pressure with new&#8208;onset atrial fibrillation in patients with hypertension and left ventricular hypertrophy&#58; the Losartan Intervention For Endpoint &#40;LIFE&#41; reduction in hypertension study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;C&#46;K&#46; Larstorp"
                            1 => "I&#46; Ariansen"
                            2 => "K&#46; Gjesdal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/HYPERTENSIONAHA.112.195032"
                      "Revista" => array:6 [
                        "tituloSerie" => "Hypertension&#46;"
                        "fecha" => "2012"
                        "volumen" => "60"
                        "paginaInicial" => "347"
                        "paginaFinal" => "353"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22753219"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulse pressure risk of new&#8208;onset atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46;F&#46; Mitchell"
                            1 => "R&#46;S&#46; Vasan"
                            2 => "M&#46;J&#46; Keyes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jama.297.7.709"
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA&#46;"
                        "fecha" => "2007"
                        "volumen" => "297"
                        "paginaInicial" => "709"
                        "paginaFinal" => "715"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17312290"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Relation of systolic&#44; diastolic&#44; and pulse pressures and aortic distensibility with atrial fibrillation &#40;from the Multi&#8208;Ethnic Study of Atherosclerosis&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46;S&#46; Roetker"
                            1 => "L&#46;Y&#46; Chen"
                            2 => "S&#46;R&#46; Heckbert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.amjcard.2014.05.041"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Cardiol&#46;"
                        "fecha" => "2014"
                        "volumen" => "114"
                        "paginaInicial" => "587"
                        "paginaFinal" => "592"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24996553"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "P&#8208;wave dispersion&#58; What we know till now&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Okutucu"
                            1 => "K&#46; Aytemir"
                            2 => "A&#46; Oto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "JRSM Cardiovasc Dis&#46;"
                        "fecha" => "2016"
                        "volumen" => "5"
                        "paginaInicial" => "1"
                        "paginaFinal" => "9"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Are maximum P wave duration and P wave dispersion a marker of target organ damage in the hypertensive population&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "N&#46; Dagli"
                            1 => "I&#46; Karaca"
                            2 => "M&#46; Yavuzkir"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00392-007-0587-8"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Res Cardiol&#46;"
                        "fecha" => "2008"
                        "volumen" => "97"
                        "paginaInicial" => "98"
                        "paginaFinal" => "104"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17938849"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "P&#8208;wave duration and P&#8208;wave dispersion in patients with dilated cardiomyopathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "K&#46; Senen"
                            1 => "H&#46; Turhan"
                            2 => "A&#46; Riza Erbay"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ejheart.2003.12.020"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Heart Fail&#46;"
                        "fecha" => "2004"
                        "volumen" => "6"
                        "paginaInicial" => "567"
                        "paginaFinal" => "569"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15302004"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long&#8208;term effects of beta blocker therapy on P&#8208;wave duration and dispersion in congestive heart failure patients&#58; a new effect&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Camsari"
                            1 => "H&#46; Pekdemir"
                            2 => "M&#46;N&#46; Akkus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1054/jelc.2003.50020"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Electrocardiol&#46;"
                        "fecha" => "2003"
                        "volumen" => "36"
                        "paginaInicial" => "111"
                        "paginaFinal" => "116"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12764693"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Improvement of atrial function and atrial reverse remodeling after cardiac resynchronization therapy for heart failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46;M&#46; Yu"
                            1 => "F&#46; Fang"
                            2 => "Q&#46; Zhang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jacc.2007.04.073"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Coll Cardiol&#46;"
                        "fecha" => "2007"
                        "volumen" => "50"
                        "paginaInicial" => "778"
                        "paginaFinal" => "785"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17707183"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Improvement of P wave dispersion after cardiac resynchronization therapy for heart failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46; Ding"
                            1 => "W&#46; Hua"
                            2 => "S&#46; Zhang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jelectrocard.2009.02.005"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Electrocardiol&#46;"
                        "fecha" => "2009"
                        "volumen" => "42"
                        "paginaInicial" => "334"
                        "paginaFinal" => "338"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19539810"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Abnormal P&#8208;wave terminal force in lead V1 is associated with cardiac death or hospitalization for heart failure in prior myocardial infarction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46; Liu"
                            1 => "A&#46; Tamura"
                            2 => "K&#46; Torigoe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00380-012-0307-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Heart Vessels&#46;"
                        "fecha" => "2013"
                        "volumen" => "28"
                        "paginaInicial" => "690"
                        "paginaFinal" => "695"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23160859"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ethnic distribution of ECG predictors of atrial fibrillation and its impact on understanding the ethnic distribution of ischemic stroke in the Atherosclerosis Risk in Communities &#40;ARIC&#41; study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "E&#46;Z&#46; Soliman"
                            1 => "R&#46;J&#46; Prineas"
                            2 => "L&#46;D&#46; Case"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.108.534735"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2009"
                        "volumen" => "40"
                        "paginaInicial" => "1204"
                        "paginaFinal" => "1211"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19213946"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Electrocardiographic left atrial abnormalities and risk of ischemic stroke"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46; Kohsaka"
                            1 => "R&#46;R&#46; Sciacca"
                            2 => "K&#46; Sugioka"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/01.STR.0000185682.09981.26"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2005"
                        "volumen" => "36"
                        "paginaInicial" => "2481"
                        "paginaFinal" => "2483"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16210557"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Early changes in atrial conduction times in hypertensive patients with elevated pulse pressure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46; &#199;imen"
                            1 => "H&#46; Sunman"
                            2 => "T&#46; Han"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Port Cardiol&#46;"
                        "fecha" => "2017"
                        "volumen" => "36"
                        "paginaInicial" => "453"
                        "paginaFinal" => "459"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/08702551/0000003600000006/v2_201706240150/S0870255117303487/v2_201706240150/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "29261"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Artigos Originais"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08702551/0000003600000006/v2_201706240150/S0870255117303487/v2_201706240150/pt/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117303487?idApp=UINPBA00004E"
]
Informação do artigo
ISSN: 08702551
Idioma original: Português
Dados atualizados diariamente
Ano/Mês Html Pdf Total
2024 Novembro 35 10 45
2024 Outubro 356 60 416
2024 Setembro 293 55 348
2024 Agosto 312 58 370
2024 Julho 248 50 298
2024 Junho 230 41 271
2024 Maio 254 34 288
2024 Abril 265 43 308
2024 Maro 281 28 309
2024 Fevereiro 337 30 367
2024 Janeiro 301 41 342
2023 Dezembro 286 31 317
2023 Novembro 406 40 446
2023 Outubro 354 22 376
2023 Setembro 364 32 396
2023 Agosto 559 24 583
2023 Julho 420 15 435
2023 Junho 312 23 335
2023 Maio 353 32 385
2023 Abril 289 6 295
2023 Maro 223 28 251
2023 Fevereiro 204 17 221
2023 Janeiro 197 24 221
2022 Dezembro 155 16 171
2022 Novembro 176 27 203
2022 Outubro 213 27 240
2022 Setembro 223 34 257
2022 Agosto 194 35 229
2022 Julho 159 45 204
2022 Junho 160 25 185
2022 Maio 143 32 175
2022 Abril 171 33 204
2022 Maro 136 33 169
2022 Fevereiro 110 37 147
2022 Janeiro 151 25 176
2021 Dezembro 108 30 138
2021 Novembro 114 37 151
2021 Outubro 112 41 153
2021 Setembro 131 27 158
2021 Agosto 99 43 142
2021 Julho 86 32 118
2021 Junho 95 27 122
2021 Maio 115 35 150
2021 Abril 102 27 129
2021 Maro 137 26 163
2021 Fevereiro 152 17 169
2021 Janeiro 74 14 88
2020 Dezembro 67 13 80
2020 Novembro 102 15 117
2020 Outubro 100 17 117
2020 Setembro 89 14 103
2020 Agosto 50 7 57
2020 Julho 96 9 105
2020 Junho 76 8 84
2020 Maio 57 10 67
2020 Abril 63 17 80
2020 Maro 86 14 100
2020 Fevereiro 163 32 195
2020 Janeiro 98 7 105
2019 Dezembro 69 5 74
2019 Novembro 64 15 79
2019 Outubro 234 25 259
2019 Setembro 111 5 116
2019 Agosto 46 11 57
2019 Julho 73 8 81
2019 Junho 89 9 98
2019 Maio 64 13 77
2019 Abril 44 15 59
2019 Maro 90 12 102
2019 Fevereiro 42 14 56
2019 Janeiro 78 6 84
2018 Dezembro 82 12 94
2018 Novembro 56 7 63
2018 Outubro 149 20 169
2018 Setembro 33 17 50
2018 Agosto 35 7 42
2018 Julho 22 6 28
2018 Junho 32 9 41
2018 Maio 56 11 67
2018 Abril 58 16 74
2018 Maro 93 11 104
2018 Fevereiro 37 9 46
2018 Janeiro 73 8 81
2017 Dezembro 127 17 144
2017 Novembro 45 21 66
2017 Outubro 26 18 44
2017 Setembro 40 17 57
2017 Agosto 58 20 78
2017 Julho 82 33 115
2017 Junho 31 29 60
Mostrar tudo

Siga este link para acessar o texto completo do artigo

Idiomas
Revista Portuguesa de Cardiologia
en pt

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

Ao assinalar que é «Profissional de Saúde», declara conhecer e aceitar que a responsável pelo tratamento dos dados pessoais dos utilizadores da página de internet da Revista Portuguesa de Cardiologia (RPC), é esta entidade, com sede no Campo Grande, n.º 28, 13.º, 1700-093 Lisboa, com os telefones 217 970 685 e 217 817 630, fax 217 931 095 e com o endereço de correio eletrónico revista@spc.pt. Declaro para todos os fins, que assumo inteira responsabilidade pela veracidade e exatidão da afirmação aqui fornecida.