Image in Cardiology
Bioresorbable vascular scaffold restenosis treated with sirolimus-eluting balloon: Optical coherence tomography findings
Restenose de stent vascular biorreabsorvível tratada com balão coberto de sirolimus: achados da tomografia de coerência ótica
Javier Cuesta
, Marcos García-Guimaraes, Teresa Bastante, Fernando Rivero, Ramón Maruri, Fernando Alfonso
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Hospital Universitario de La Princesa, Madrid, Spain
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Francisco, Miguel Nobre de Menezes, Fausto J. Pinto, Pedro Canas da Silva" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Ana Rita G." "apellidos" => "Francisco" ] 1 => array:2 [ "nombre" => "Miguel" "apellidos" => "Nobre de Menezes" ] 2 => array:2 [ "nombre" => "Fausto J." "apellidos" => "Pinto" ] 3 => array:2 [ "nombre" => "Pedro" "apellidos" => "Canas da Silva" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2174204918301302" "doi" => "10.1016/j.repce.2017.03.011" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204918301302?idApp=UINPBA00004E" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S087025511730094X?idApp=UINPBA00004E" "url" => "/08702551/0000003700000004/v1_201805040411/S087025511730094X/v1_201805040411/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in Cardiology</span>" "titulo" => "Bioresorbable vascular scaffold restenosis treated with sirolimus-eluting balloon: Optical coherence tomography findings" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "359" "paginaFinal" => "360" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Javier Cuesta, Marcos García-Guimaraes, Teresa Bastante, Fernando Rivero, Ramón Maruri, Fernando Alfonso" "autores" => array:6 [ 0 => array:4 [ "nombre" => "Javier" "apellidos" => "Cuesta" "email" => array:1 [ 0 => "javicuestacuesta@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Marcos" "apellidos" => "García-Guimaraes" ] 2 => array:2 [ "nombre" => "Teresa" "apellidos" => "Bastante" ] 3 => array:2 [ "nombre" => "Fernando" "apellidos" => "Rivero" ] 4 => array:2 [ "nombre" => "Ramón" "apellidos" => "Maruri" ] 5 => array:2 [ "nombre" => "Fernando" "apellidos" => "Alfonso" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Hospital Universitario de La Princesa, Madrid, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Restenose de <span class="elsevierStyleItalic">stent</span> vascular biorreabsorvível tratada com balão coberto de sirolimus: achados da tomografia de coerência ótica" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 761 "Ancho" => 1867 "Tamanyo" => 288350 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Coronary angiography. (A) A BVS was implanted in the proximal segment of the left anterior descending coronary artery two years ago (white arrows). (B) Severe restenosis was observed (yellow arrow). (C) Excellent outcome after sirolimus-eluting balloon (yellow arrow).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 60-year-old man was admitted for unstable angina. Two-years ago he was treated with two bioresorbable vascular scaffolds (BVSs) on the proximal and distal segments of the left anterior descending coronary artery (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>A, white arrows). Coronary angiography showed critical in-scaffold restenosis of the proximal BVS (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>B, yellow arrow). Optical coherence tomography revealed heterogeneous tissue filling the BVS (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>, A, B and D) with areas depicting bright neointimal hyperplasia with dorsal attenuation and marked shadowing of the underlying BVS struts. There was no evidence of scaffold disruption and neoatherosclerosis was considered the cause of late BVS failure. The patient was treated with a 3×15-mm sirolimus coated balloon catheter (drug-eluting balloon, DEB) (ratio of drug-eluting balloon to BVS size: 1:1) (MagicTouch™, Concept Medical Inc.) with excellent angiographic (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>C) and optical coherence tomography (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>, C and E) outcomes.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The unique properties of BVS, which provide the benefits of a powerful antiproliferative drug without the need for a permanent metal layer, make this device an attractive strategy during coronary interventions. Late BVS failure is a rare event and the treatment of choice for BVS restenosis has yet to be established.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Sirolimus-eluting balloons provide a novel, highly attractive therapy for patients with in-stent restenosis, but there are very limited data about the use of DEB in this context. Furthermore, the relative efficacy of this novel therapeutic modality, as compared with second-generation drug-eluting stents (DESs), has not yet been established. The use of DEB for BVS restenosis would avoid the need for an additional permanent metal layer (“leave nothing behind” strategy). This could be of particular value when excellent final outcomes are obtained, as in our case. To the best of our knowledge, this is the first report describing the use of sirolimus-eluting balloons for late BVS failure as a result of neoatherosclerosis.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0020" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:1 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of interest" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2017-02-08" "fechaAceptado" => "2017-07-13" "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 761 "Ancho" => 1867 "Tamanyo" => 288350 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Coronary angiography. (A) A BVS was implanted in the proximal segment of the left anterior descending coronary artery two years ago (white arrows). (B) Severe restenosis was observed (yellow arrow). (C) Excellent outcome after sirolimus-eluting balloon (yellow arrow).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2077 "Ancho" => 2333 "Tamanyo" => 977650 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Optical coherence tomography. (A–B) Severe restenosis due to neoatherosclerosis. (C) Excellent outcome after sirolimus-eluting balloon. (D) Longitudinal view before treatment. (E) Longitudinal view after treatment. (*: wire artefact).</p>" ] ] ] ] "idiomaDefecto" => "en" "url" => "/08702551/0000003700000004/v1_201805040411/S0870255117301105/v1_201805040411/en/main.assets" "Apartado" => array:4 [ "identificador" => "29264" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Imagens em Cardiologia" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/08702551/0000003700000004/v1_201805040411/S0870255117301105/v1_201805040411/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117301105?idApp=UINPBA00004E" ]
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