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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Indica&#231;&#227;o prim&#225;ria para a coloca&#231;&#227;o da oxigena&#231;&#227;o por membrana extracorporal e mortalidade&#44; &#8224; &#8208; morte&#46; ECMO&#58; oxigena&#231;&#227;o por membrana extracorporal&#59; ECMO&#8208;VV&#58; oxigena&#231;&#227;o por membrana extracorporal venovenoso&#59; ECMO&#8208;VA&#58; oxigena&#231;&#227;o por membrana extracorporal venoarterial&#59; EAM&#58; enfarte agudo do mioc&#225;rdio&#59; IC&#58; insufici&#234;ncia card&#237;aca&#59; SDRA&#58; s&#237;ndrome de dificuldade respirat&#243;ria aguda&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introdu&#231;&#227;o</span><p id="par0125" class="elsevierStylePara elsevierViewall">A oxigena&#231;&#227;o por membrana extracorporal &#40;ECMO&#41; &#233; um dispositivo de resgate para suportar doentes com disfun&#231;&#227;o card&#237;aca e&#47;ou pulmonar grave refrat&#225;rios &#224; terap&#234;utica convencional&#46; Em adultos&#44; a sua primeira aplica&#231;&#227;o bem&#8208;sucedida foi h&#225; mais de 40 anos&#46; No entanto&#44; s&#243; recentemente a sua utiliza&#231;&#227;o se generalizou&#44; com a melhoria tecnol&#243;gica dos dispositivos dispon&#237;veis e o acumular de evid&#234;ncia cient&#237;fica que a sustenta<a class="elsevierStyleCrossRefs" href="#bib0165"><span class="elsevierStyleSup">1&#44;2</span></a>&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Fazem parte essencial de um circuito de ECMO duas c&#226;nulas <span class="elsevierStyleItalic">&#40;inflow&#47;outflow&#41;</span>&#44; uma bomba centr&#237;fuga e um oxigenador&#46; O oxigenador &#233; um dispositivo de troca de gases que usa uma membrana semiperme&#225;vel para separar um compartimento sangu&#237;neo e um gasoso&#46; O sangue desoxigenado &#233; drenado pela for&#231;a da bomba externa&#44; atravessa o oxigenador &#40;onde se processa a troca de di&#243;xido de carbono por oxig&#233;nio&#41; e &#233; devolvido ao doente&#46; Quando o sangue &#233; drenado e entregue apenas por veias&#44; o circuito denomina&#8208;se de ECMO&#8208;venovenoso &#40;VV&#41;&#44; permitindo apenas suporte pulmonar&#46; Quando &#233; drenado por uma veia e entregue numa art&#233;ria o circuito &#233; apelidado de ECMO&#8208;venoarterial &#40;VA&#41;&#44; garantindo suporte pulmonar e card&#237;aco<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">2</span></a>&#46; O ECMO &#233; um dispositivo port&#225;til e leve&#44; permitindo a mobiliza&#231;&#227;o relativamente f&#225;cil de doentes e o seu transporte intra e inter&#8208;hospital&#46; Pode ser colocado por via percut&#226;nea ou por via central&#44; dependendo das circunst&#226;ncias cl&#237;nicas&#44; sendo inclusivamente poss&#237;vel a sua utiliza&#231;&#227;o em situa&#231;&#245;es de paragem cardiorrespirat&#243;ria &#40;PCR&#41;&#46; Apesar de ser um suporte tempor&#225;rio e com naturais limita&#231;&#245;es&#44; a sua versatilidade torna&#8208;o um dispositivo &#250;til em diversos cen&#225;rios cl&#237;nicos&#44; desde a estabiliza&#231;&#227;o cl&#237;nica para a recupera&#231;&#227;o total&#44; at&#233; situa&#231;&#245;es em que funciona como ponte para a decis&#227;o terap&#234;utica&#44; quer esta passe por um <span class="elsevierStyleItalic">upgrade</span> para suporte ventricular de longa dura&#231;&#227;o&#44; transplante ou&#44; inclusivamente&#44; a pr&#243;pria suspens&#227;o do suporte<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">3</span></a>&#46; Nas &#250;ltimas recomenda&#231;&#245;es da Sociedade Europeia de Cardiologia&#44; o ECMO&#8208;VA &#233; recomendado para doentes em <span class="elsevierStyleItalic">Intermacs</span> 1 e 2<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">4</span></a>&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">Neste trabalho&#44; temos como objetivo descrever as caracter&#237;sticas demogr&#225;ficas&#44; a indica&#231;&#227;o&#44; as comorbilidades&#44; as vari&#225;veis fisiol&#243;gicas pr&#233;&#8208;ECMO&#44; o tratamento &#40;dura&#231;&#227;o&#44; modo&#44; complica&#231;&#245;es&#41; e a mortalidade &#40;em ECMO e intra&#8208;hospitalar&#41; de uma popula&#231;&#227;o de doentes onde foi utilizado o ECMO &#40;num hospital terci&#225;rio&#41;&#46; Iremos&#44; ainda&#44; avaliar a exist&#234;ncia de preditores de mortalidade nesta popula&#231;&#227;o&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">M&#233;todos</span><p id="par0140" class="elsevierStylePara elsevierViewall">Este &#233; um estudo de coorte&#44; observacional e retrospetivo&#44; onde est&#227;o inclu&#237;dos todos os doentes que colocaram ECMO em duas unidades diferentes&#58; unidade de cuidados intensivos card&#237;acos &#40;UCIC&#41; e unidade de cuidados intensivos polivalente &#40;UCIP&#41;&#44; num hospital terci&#225;rio&#44; desde o primeiro doente canulado em abril de 2011 at&#233; outubro de 2016&#46; Foram exclu&#237;dos desta an&#225;lise os doentes em que o dispositivo foi colocado ap&#243;s cardiotomia&#44; j&#225; que estes foram tratados segundo protocolos de implanta&#231;&#227;o e seguimento distintos&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">Durante este per&#237;odo&#44; foram colocados 48 ECMO nestas unidades&#58; 29 por fal&#234;ncia card&#237;aca e 19 por fal&#234;ncia pulmonar&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">Realizou&#8208;se uma sele&#231;&#227;o de vari&#225;veis relevantes&#44; tendo em conta a literatura publicada&#44; e foram colhidos os dados &#40;demogr&#225;ficos&#44; comorbilidades&#44; indica&#231;&#227;o para ECMO&#41; pela an&#225;lise do processo eletr&#243;nico&#46; Nos fatores pr&#233;&#8208;ECMO foram considerados os piores resultados nas primeiras 24<span class="elsevierStyleHsp" style=""></span>h de admiss&#227;o na unidade&#46; Foi utilizada a f&#243;rmula <span class="elsevierStyleItalic">Modification of Diet in Renal Disease</span> &#40;MDRD&#41; para estimar a taxa de filtra&#231;&#227;o glomerular &#40;TFG&#41;&#46; Foram registadas as complica&#231;&#245;es relacionadas com a t&#233;cnica&#44; assim como o tempo de ECMO e de internamento&#46; As complica&#231;&#245;es relacionadas com a t&#233;cnica foram divididas em hemorr&#225;gicas &#40;do acesso&#44; gastrointestinal ou cerebral&#41;&#44; isqu&#233;micas e relacionadas com o acesso &#40;trombose&#44; disse&#231;&#227;o&#44; aneurisma&#44; pseudoaneurisma&#44; f&#237;stula&#41;&#46; A les&#227;o renal aguda foi definida utilizando o <span class="elsevierStyleItalic">score</span> RIFLE&#46; Considerou&#8208;se disfun&#231;&#227;o hematol&#243;gica a contagem de plaquetas<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>100<span class="elsevierStyleHsp" style=""></span>000<span class="elsevierStyleHsp" style=""></span>uL ou hemat&#243;crito<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>35&#37; e disfun&#231;&#227;o hep&#225;tica&#44; um n&#237;vel de transaminases tr&#234;s vezes superior ao limite superior da normalidade &#40;LSN&#41;&#46; Colheram&#8208;se os dados referentes &#224; mortalidade em ECMO&#44; p&#243;s&#8208;ECMO e intra&#8208;hospitalar&#46; Foi considerada descanula&#231;&#227;o com sucesso quando realizada com a inten&#231;&#227;o de sobreviv&#234;ncia ou como ponte para outro suporte&#46; Foram feitas an&#225;lises entre os grupos&#58; ECMO&#8208;VA e ECMO&#8208;VV e entre os sobreviventes e n&#227;o sobreviventes dentro de cada um dos grupos&#46; Para previs&#227;o de sobreviv&#234;ncia ap&#243;s ECMO&#8208;VA utilizou&#8208;se o Survival After Veno&#8208;arterial ECMO &#8211; score &#40;SAVE&#8208;score&#41;&#46; Este <span class="elsevierStyleItalic">score</span> utiliza um sistema de pontua&#231;&#227;o &#40;&#8208;35 a 17&#41; que tem em linha de conta o diagn&#243;stico&#44; a idade&#44; peso&#44; outras disfun&#231;&#245;es agudas ou cr&#243;nicas&#44; par&#226;metros de ventila&#231;&#227;o e tempo pr&#233;vio de intuba&#231;&#227;o orotraqueal&#44; PCR pr&#233;via e par&#226;metros hemodin&#226;micos&#46; Os doentes s&#227;o estratificados em cinco classes de risco&#44; estando associada a cada classe a sobreviv&#234;ncia esperada&#58; classe <span class="elsevierStyleSmallCaps">I</span> &#40;SAVE&#8208;<span class="elsevierStyleItalic">score</span><span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>5&#41; 75&#37; de sobreviv&#234;ncia&#44; classe <span class="elsevierStyleSmallCaps">II</span> &#40;SAVE&#8208;<span class="elsevierStyleItalic">score</span> 1 a 5&#41; 58&#37;&#59; classe <span class="elsevierStyleSmallCaps">III</span> &#40;SAVE&#8208;<span class="elsevierStyleItalic">score</span> &#8208;4 a 0&#41; 42&#37;&#59; classe <span class="elsevierStyleSmallCaps">IV</span> &#40;SAVE&#8208;<span class="elsevierStyleItalic">score</span> &#8208;9 a &#8208;5&#41; 30&#37; e classe <span class="elsevierStyleSmallCaps">V</span> &#40;&#8804;<span class="elsevierStyleHsp" style=""></span>&#8208;10&#41; 18&#37;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">5</span></a>&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">Todos os dispositivos foram colocados por via percut&#226;nea&#44; quer na pr&#243;pria unidade quer no laborat&#243;rio de hemodin&#226;mica&#44; por uma equipa multidisciplinar composta por intensivistas&#44; cardiologistas&#44; perfusionistas e enfermeiros&#46; Todos&#44; &#224; exce&#231;&#227;o de um doente&#44; utilizaram o sistema CARDIOHELP da <span class="elsevierStyleItalic">Maquet&#44; Hirrlingen&#44; Alemanha</span>&#46; No caso do ECMO&#8208;VA&#44; foram maioritariamente utilizados os acessos femorais e para o ECMO&#8208;VV um acesso femoral e um jugular&#46; A c&#226;nula de reperfus&#227;o distal foi utilizada por rotina quando o motivo do ECMO era o enfarte agudo do mioc&#225;rdio &#40;EAM&#41;&#46; Nas restantes indica&#231;&#245;es foi colocada quando havia evid&#234;ncia cl&#237;nica de m&#225; perfus&#227;o distal&#44; sempre com controlo ecogr&#225;fico&#46; Quanto &#224; hipocoagula&#231;&#227;o&#44; foi realizado um b&#243;lus de heparina n&#227;o fracionada &#40;HNF&#41; na altura da canula&#231;&#227;o &#40;50&#8208;100<span class="elsevierStyleHsp" style=""></span>U&#47;Kg&#44; m&#225;ximo de 5000<span class="elsevierStyleHsp" style=""></span>U&#41;&#44; seguido por uma perfus&#227;o ajustada para um tempo de tromboplastina parcial ativada &#40;APTT&#41; alvo de 1&#44;5 vezes o LSN&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">A assist&#234;ncia ventricular cir&#250;rgica foi utilizada quando havia fal&#234;ncia farmacol&#243;gica e mec&#226;nica no <span class="elsevierStyleItalic">venting</span> do ventr&#237;culo esquerdo &#40;VE&#41;&#46; A referencia&#231;&#227;o para transplante card&#237;aco &#40;n&#227;o dispon&#237;vel no nosso centro&#41; foi realizada sempre que a etiologia ou evolu&#231;&#227;o do doente demonstravam uma baixa probabilidade de recupera&#231;&#227;o da fun&#231;&#227;o ventricular esquerda&#46; Recentemente&#44; foi estabelecido um protocolo de referencia&#231;&#227;o com um dos centros nacionais de maior volume&#46;</p><p id="par0165" class="elsevierStylePara elsevierViewall">A an&#225;lise estat&#237;stica foi realizada utilizando o IBM SPSS&#44; vers&#227;o 19&#46; As vari&#225;veis cont&#237;nuas s&#227;o apresentadas como m&#233;dia com desvio&#8208;padr&#227;o e comparadas atrav&#233;s do teste <span class="elsevierStyleItalic">T Student</span> ou teste <span class="elsevierStyleItalic">Mann&#8208;Whitney U</span>&#44; conforme a normalidade&#46; As vari&#225;veis categ&#243;ricas s&#227;o apresentadas segundo percentagens e a compara&#231;&#227;o entre elas foi realizada utilizando o teste do quiquadrado ou de <span class="elsevierStyleItalic">Fisher</span>&#44; como apropriado&#46; Todos os resultados s&#227;o <span class="elsevierStyleItalic">2&#8208;sided</span> e um valor de p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05 foi considerado estatisticamente significativo&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Caracteriza&#231;&#227;o da popula&#231;&#227;o</span><p id="par0170" class="elsevierStylePara elsevierViewall">Entre abril de 2011 e outubro de 2016&#44; 48 doentes colocaram ECMO&#58; 29 ECMO&#8208;VA e 19 ECMO&#8208;VV&#46; A indica&#231;&#227;o mais comum para coloca&#231;&#227;o de ECMO&#8208;VA foi o EAM com evolu&#231;&#227;o em choque cardiog&#233;nico&#46; A s&#237;ndrome de dificuldade respirat&#243;ria aguda &#40;SDRA&#41;&#44; secund&#225;ria a infe&#231;&#227;o viral&#44; foi a causa mais comum de coloca&#231;&#227;o de ECMO&#8208;VV&#46; As restantes indica&#231;&#245;es est&#227;o expostas na <a class="elsevierStyleCrossRef" href="#fig0005">Figura 1</a>&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0095" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Oxigena&#231;&#227;o por membrana extracorporal venoarterial</span><p id="par0175" class="elsevierStylePara elsevierViewall">Dos doentes que colocaram ECMO&#8208;VA&#44; 26 estavam internados na UCIC e tr&#234;s na UCIP&#46; Estes &#250;ltimos eram doentes com fal&#234;ncia cardiovascular secund&#225;ria a infe&#231;&#227;o respirat&#243;ria grave&#46;</p><p id="par0180" class="elsevierStylePara elsevierViewall">A idade m&#233;dia era de 51&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#44;6 anos e 51&#44;7&#37; eram do sexo masculino&#46; Cerca de metade dos doentes que colocaram ECMO&#8208;VA foram transferidos de outro hospital em choque cardiog&#233;nico&#46; O tempo m&#233;dio entre o diagn&#243;stico e a coloca&#231;&#227;o do dispositivo foi de 51<span class="elsevierStyleHsp" style=""></span>h&#44; sendo que 12 doentes foram ventilados e canulados na mesma altura &#40;41&#37;&#41;&#46; Treze doentes tiveram PCR intra&#8208;hospitalar pr&#233;&#8208;coloca&#231;&#227;o de dispositivo e o tempo m&#233;dio de retorno de circula&#231;&#227;o espont&#226;nea &#40;RCE&#41; foi de 8&#44;5<span class="elsevierStyleHsp" style=""></span>min&#46; Em tr&#234;s destes doentes o ECMO foi colocado em PCR&#46; O SAVE&#8208;<span class="elsevierStyleItalic">score</span> m&#233;dio foi de &#8208;4&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;9 e a mediana foi de &#8208;4&#44;5 &#40;IQR &#8208;0&#44;25&#47;&#8208;8&#41;&#46; Foram utilizados dispositivos de <span class="elsevierStyleItalic">venting</span> em oito doentes &#40;cinco bal&#245;es intra&#8208;a&#243;rticos &#91;BIA&#93; e tr&#234;s Impella CP<span class="elsevierStyleSup">&#174;</span>&#41;&#46; Num dos doentes foi necess&#225;rio implantar uma segunda c&#226;nula venosa jugular para otimiza&#231;&#227;o da oxigena&#231;&#227;o coron&#225;ria e cerebral &#8211; ECMO V&#8208;A&#8208;V</p></span><span id="sec0100" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Oxigena&#231;&#227;o por membrana extracorporal venovenosa</span><p id="par0185" class="elsevierStylePara elsevierViewall">Dos doentes com ECMO&#8208;VV&#44; 17 estavam internados na UCIP e dois na UCIC &#40;estes &#250;ltimos colocados por pneumonia grave com ARDS secund&#225;rio&#41;&#46;</p><p id="par0190" class="elsevierStylePara elsevierViewall">A idade m&#233;dia era de 48&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#44;1 anos e 52&#44;6&#37; eram do sexo masculino&#46; O tempo m&#233;dio entre o diagn&#243;stico e a coloca&#231;&#227;o do dispositivo foi de 9&#44;5 dias&#46; Na altura de coloca&#231;&#227;o de ECMO&#44; todos os doentes j&#225; estavam ventilados&#44; sendo o tempo m&#233;dio entre o in&#237;cio de ventila&#231;&#227;o e a coloca&#231;&#227;o do dispositivo de 4&#44;6 dias&#46; Dos 16 doentes que colocaram ECMO&#8208;VV por SDRA&#44; em dez foi utilizada a t&#233;cnica de <span class="elsevierStyleItalic">prone</span> pr&#233;&#8208;ECMO e todos&#44; &#224; exce&#231;&#227;o de um doente&#44; fizeram bloqueio neuromuscular&#46; Todos os doentes tinham <span class="elsevierStyleItalic">score</span> de Murray<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>3&#46;</p></span><span id="sec0105" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Oxigena&#231;&#227;o por membrana extracorporal venoarterial vs venovenosa</span><p id="par0195" class="elsevierStylePara elsevierViewall">Na an&#225;lise comparativa entre as duas modalidades de ECMO&#44; os doentes com ECMO&#8208;VA foram mais frequentemente transferidos de outro hospital &#40;41&#44;4 <span class="elsevierStyleItalic">versus</span> 5&#44;3&#37;&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;006&#41;&#44; tinham menor tempo entre o diagn&#243;stico e a coloca&#231;&#227;o do dispositivo &#40;50&#44;7 <span class="elsevierStyleItalic">versus</span> 227&#44;4<span class="elsevierStyleHsp" style=""></span>h&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;007&#41; e menor tempo de ventila&#231;&#227;o mec&#226;nica invasiva &#40;VMI&#41; pr&#233;via &#40;9&#44;3 <span class="elsevierStyleItalic">versus</span> 110&#44;7<span class="elsevierStyleHsp" style=""></span>h&#44; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; O contexto de PCR pr&#233;&#8208;implante do dispositivo foi mais frequente nos ECMO&#8208;VA &#40;44&#44;8 <span class="elsevierStyleItalic">versus</span> 5&#44;3&#37;&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;003&#41;&#46; Nas primeiras 24<span class="elsevierStyleHsp" style=""></span>h de perman&#234;ncia na unidade de cuidados intensivos&#44; os doentes em ECMO&#8208;VA tinham&#58; n&#237;vel m&#233;dio de lactato s&#233;rico &#40;6&#44;5 <span class="elsevierStyleItalic">versus</span> 2&#44;1<span class="elsevierStyleHsp" style=""></span>mmol&#47;L&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e AST &#40;1253&#44;9 <span class="elsevierStyleItalic">versus</span> 159&#44;6 u&#47;L&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;02&#41; superiores aos dos doentes em ECMO&#8208;VV&#44; disfun&#231;&#227;o renal moderada a grave mais frequente &#40;72&#44;4 <span class="elsevierStyleItalic">versus</span> 36&#44;8&#37;&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;015&#41;&#44; assim como valor m&#233;dio de bicarbonato s&#233;rico inferior &#40;17&#44;2 <span class="elsevierStyleItalic">versus</span> 24&#44;4<span class="elsevierStyleHsp" style=""></span>mmol&#47;L&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><p id="par0200" class="elsevierStylePara elsevierViewall">Na <a class="elsevierStyleCrossRef" href="#tbl0005">Tabela 1</a> encontram&#8208;se os restantes dados que caraterizam esta popula&#231;&#227;o&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Complica&#231;&#245;es</span><p id="par0205" class="elsevierStylePara elsevierViewall">A complica&#231;&#227;o mais frequente no grupo ECMO&#8208;VA foi a isquemia do membro inferior&#44; com uma preval&#234;ncia de 20&#44;7&#37; &#40;seis doentes&#41;&#46; Tr&#234;s destes necessitaram de fasciotomia urgente&#44; por s&#237;ndrome de compartimento&#44; e um doente realizou amputa&#231;&#227;o infracondiliana do membro inferior por isquemia irrevers&#237;vel&#46;</p><p id="par0210" class="elsevierStylePara elsevierViewall">No ECMO&#8208;VV foram mais frequentes as complica&#231;&#245;es relacionadas com o acesso&#58; 21&#44;1&#37; de hemorragias pelo local de acesso e 15&#44;8&#37; de complica&#231;&#245;es relacionadas com o vaso &#40;um doente com trombo detetado na c&#226;nula durante a remo&#231;&#227;o&#44; um doente com prov&#225;vel s&#237;ndrome da veia cava superior e um doente com f&#237;stula entre a veia e a art&#233;ria femoral de baixo d&#233;bito&#41;&#46; Nesta popula&#231;&#227;o&#44; houve apenas uma complica&#231;&#227;o hemorr&#225;gica <span class="elsevierStyleItalic">major</span> &#40;hemorragia digestiva alta por &#250;lcera g&#225;strica de stresse complicada&#41; com necessidade de interven&#231;&#227;o cir&#250;rgica&#46;</p><p id="par0215" class="elsevierStylePara elsevierViewall">Apesar da maior frequ&#234;ncia de complica&#231;&#245;es hemorr&#225;gicas no grupo ECMO&#8208;VV&#44; n&#227;o houve diferen&#231;as estatisticamente significativas quanto &#224; necessidade de transfus&#227;o de hemoderivados&#46; Houve apenas um caso de trombocitopenia induzida pela heparina&#44; resolvida com o recurso a lepirudina e um caso de coagula&#231;&#227;o intravascular disseminada &#40;morte&#41;&#46; A disfun&#231;&#227;o renal aguda e a necessidade de t&#233;cnica de substitui&#231;&#227;o renal &#40;TSR&#41; foram significativamente mais frequentes nos doentes em ECMO&#8208;VA &#40;insufici&#234;ncia renal aguda &#91;IRA&#93;&#58; 75&#44;9 <span class="elsevierStyleItalic">versus</span> 36&#44;8&#37;&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;007&#59; e TSR&#58; 34&#44;5 <span class="elsevierStyleItalic">versus</span> 5&#44;3&#37;&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;032&#41;&#46;</p><p id="par0220" class="elsevierStylePara elsevierViewall">A disfun&#231;&#227;o hematol&#243;gica foi a mais frequente no ECMO&#8208;VV&#44; ocorrendo em 68&#44;4&#37; dos doentes&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Destino&#47;mortalidade</span><p id="par0225" class="elsevierStylePara elsevierViewall">O ECMO foi utilizado como ponte para transplante ou para dispositivo de suporte ventricular de longa dura&#231;&#227;o em 12 doentes&#46; No ECMO&#8208;VA&#44; nove doentes foram referenciados para transplante card&#237;aco&#58; tr&#234;s doentes foram transplantados &#40;apenas um sobreviveu&#41;&#44; dois doentes colocaram <span class="elsevierStyleItalic">Berlin&#8208;Heart</span> &#40;morte&#41; e os restantes faleceram a aguardar transplante&#46; No ECMO&#8208;VV&#44; tr&#234;s doentes foram referenciados para transplante pulmonar&#58; dois faleceram em lista de espera e um doente foi recusado&#44; sendo retirado o suporte&#46; Os dois doentes que faleceram a aguardar transplante estavam sem seda&#231;&#227;o e em ventila&#231;&#227;o espont&#226;nea&#44; cumprindo programa de reabilita&#231;&#227;o ativa na UCIP&#46;</p><p id="par0230" class="elsevierStylePara elsevierViewall">Foram descanulados com sucesso 69&#37; dos doentes em ECMO&#8208;VA e 78&#44;9&#37; dos doentes em ECMO&#8208;VV&#46; O tempo m&#233;dio de ECMO foi significativamente inferior nos doentes em ECMO&#8208;VA em rela&#231;&#227;o aos em ECMO&#8208;VV &#40;119&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>104&#44;3 <span class="elsevierStyleItalic">versus</span> 263&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>153&#44;2<span class="elsevierStyleHsp" style=""></span>h&#44; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; assim como os dias de internamento &#40;11&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;2 <span class="elsevierStyleItalic">versus</span> 40&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&#44;8 dias&#44; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><p id="par0235" class="elsevierStylePara elsevierViewall">Tiveram alta hospitalar 37&#44;9&#37; dos doentes em ECMO&#8208;VA e 63&#44;2&#37; dos em ECMO&#8208;VV&#46; Importa referir que a mortalidade em ambos os grupos est&#225; influenciada pela inclus&#227;o de doentes que esperavam &#243;rg&#227;o para transplante&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Preditores de mortalidade</span><p id="par0240" class="elsevierStylePara elsevierViewall">No ECMO&#8208;VA&#44; na an&#225;lise univariada&#44; verificamos que o &#250;nico preditor de mortalidade foi o n&#250;mero m&#233;dio de agentes inotr&#243;picos &#40;1&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;5 <span class="elsevierStyleItalic">versus</span> 2&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;6&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;004&#41;&#46; Verificou&#8208;se&#44; ainda&#44; uma tend&#234;ncia para os sobreviventes apresentarem leuc&#243;citos mais baixo &#224; admiss&#227;o &#40;13&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;3 <span class="elsevierStyleItalic">versus</span> 18&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;2<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>10&#94;3&#47;uL&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;051&#41; e maior tempo m&#233;dio de internamento &#40;15&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;0 <span class="elsevierStyleItalic">versus</span> 9&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;7 dias&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;082&#41;&#46;</p><p id="par0245" class="elsevierStylePara elsevierViewall">Os sobreviventes no ECMO&#8208;VV apresentaram&#44; tendencialmente&#44; tempo m&#233;dio entre o diagn&#243;stico e a coloca&#231;&#227;o do dispositivo inferior &#40;132&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>128&#44;0 <span class="elsevierStyleItalic">versus</span> 390&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>318&#44;6<span class="elsevierStyleHsp" style=""></span>h&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;078&#41; &#40;ver <a class="elsevierStyleCrossRefs" href="#tbl0010">Tabelas 2 e 3</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><elsevierMultimedia ident="tbl0015"></elsevierMultimedia></span></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Discuss&#227;o</span><p id="par0250" class="elsevierStylePara elsevierViewall">Ao longo de cinco anos&#44; foram colocados em ECMO 48 doentes&#58; 29 por fal&#234;ncia cardiovascular e 19 por fal&#234;ncia respirat&#243;ria&#46; Pela an&#225;lise da <a class="elsevierStyleCrossRef" href="#tbl0005">Tabela 1</a>&#44; verificamos que os doentes em ECMO&#8208;VA t&#234;m&#44; pelo menos inicialmente&#44; marcadores de doen&#231;a mais grave&#58; valores de lactato s&#233;rico e AST mais elevados&#44; maior preval&#234;ncia de disfun&#231;&#227;o renal moderada a grave&#44; assim como bicarbonato s&#233;rico mais baixo&#46; O menor tempo entre o diagn&#243;stico e a coloca&#231;&#227;o do ECMO&#44; assim como de VMI pr&#233;via&#44; &#233; explicado pela maior gravidade de apresenta&#231;&#227;o cl&#237;nica&#46; Quase metade dos doentes em ECMO&#8208;VA foi transferida em choque cardiog&#233;nico de outro hospital&#59; estes s&#227;o doentes que provavelmente apresentam maior tempo de evolu&#231;&#227;o do choque&#44; o que condiciona maior progress&#227;o nas disfun&#231;&#245;es de &#243;rg&#227;o associadas&#46;</p><p id="par0255" class="elsevierStylePara elsevierViewall">Na nossa coorte foram utilizadas t&#233;cnicas percut&#226;neas de descompress&#227;o do VE em cerca de 30&#37; dos doentes&#46; Outras medidas&#44; como a redu&#231;&#227;o da p&#243;s&#8208;carga&#44; o uso de vasodilatadores arteriais&#44; de inotr&#243;picos&#44; a restri&#231;&#227;o de fluidos e a hemofiltra&#231;&#227;o&#44; podem ajudar a prevenir esta complica&#231;&#227;o e foram utilizadas de forma sistem&#225;tica em todos os casos<a class="elsevierStyleCrossRefs" href="#bib0190"><span class="elsevierStyleSup">6&#8211;8</span></a>&#46; Est&#225; descrito que a distens&#227;o do VE&#44; que compromete a recupera&#231;&#227;o e leva a edema pulmonar&#44; pode ocorrer em 10&#8208;60&#37; dos doentes com ECMO&#8208;VA&#44; sendo mais comum em rec&#233;m&#8208;nascidos e crian&#231;as<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">7</span></a>&#46;</p><p id="par0260" class="elsevierStylePara elsevierViewall">A hipocoagula&#231;&#227;o continua a ser desafiante nestes doentes&#44; tendo em conta que o contacto entre o sangue e o circuito extracorporal gera ativa&#231;&#227;o e consumo de fatores pr&#243; e anticoagulantes&#44; dificultando o equil&#237;brio e controlo da d&#237;ade trombose&#47;hemorragia<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">9</span></a>&#46; O agente anticoagulante recomendado &#233; a HNF<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">9&#44;10</span></a>&#46; Na nossa popula&#231;&#227;o&#44; todos os doentes fizeram perfus&#227;o cont&#237;nua de heparina&#44; havendo apenas um doente com diagn&#243;stico de trombocitopenia induzida pela heparina&#46; Neste caso&#44; houve necessidade de alterar a hipocoagula&#231;&#227;o&#44; tendo sido utilizada a lepirudina&#46;</p><p id="par0265" class="elsevierStylePara elsevierViewall">Apesar do ECMO ser uma ferramenta cada vez mais utilizada para suporte de doente com fal&#234;ncia card&#237;aca ou respirat&#243;ria&#44; o seu uso est&#225; associado a complica&#231;&#245;es frequentes&#44; tendo algumas delas impacto significativo na qualidade de vida dos sobreviventes<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">6</span></a>&#46; Neste estudo ocorreram complica&#231;&#245;es hemorr&#225;gicas em dez doentes &#40;21&#37;&#41;&#46; O local mais frequente de hemorragia foi no local de inser&#231;&#227;o das c&#226;nulas&#46; Na nossa coorte&#44; a hemorragia e o maior n&#250;mero de hemoderivados transfundidos n&#227;o foram preditores de mortalidade&#44; apesar do que existe referenciado na literatura<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">3&#44;11&#8211;13</span></a>&#46; Este facto ser&#225; provavelmente explicado pela reduzida dimens&#227;o da amostra&#44; que n&#227;o permite atingir significado estat&#237;stico&#46; Na nossa s&#233;rie&#44; as complica&#231;&#245;es neurol&#243;gicas foram raras&#44; apenas documentadas num doente&#44; com hemorragia intracerebral espont&#226;nea&#46; Na literatura&#44; a incid&#234;ncia de complica&#231;&#245;es neurol&#243;gicas varia entre 15&#8208;37&#37;<a class="elsevierStyleCrossRefs" href="#bib0230"><span class="elsevierStyleSup">14&#44;15</span></a>&#46; A baixa taxa de dete&#231;&#227;o deve&#8208;se&#44; provavelmente&#44; &#224; subutiliza&#231;&#227;o da tomografia computorizada cerebral e &#224; aus&#234;ncia de investiga&#231;&#227;o an&#225;tomo&#8208;patol&#243;gica <span class="elsevierStyleItalic">post&#8208;mortem&#46;</span></p><p id="par0270" class="elsevierStylePara elsevierViewall">A isquemia aguda do membro inferior ocorreu exclusivamente em doentes com ECMO&#8208;VA &#40;6&#47;29 doentes&#41;&#46; A utiliza&#231;&#227;o da c&#226;nula de reperfus&#227;o distal e o uso contralateral da c&#226;nula venosa s&#227;o essenciais para a diminui&#231;&#227;o da incid&#234;ncia desta complica&#231;&#227;o<a class="elsevierStyleCrossRefs" href="#bib0240"><span class="elsevierStyleSup">16&#44;17</span></a>&#46; Tr&#234;s doentes necessitaram de fasciotomia urgente &#40;10&#44;3&#37; dos em ECMO&#8208;VA&#41; e um doente de amputa&#231;&#227;o do membro inferior&#46; Estes resultados s&#227;o semelhantes a outros j&#225; publicados&#44; onde a isquemia do membro inferior atinge os 10&#8208;30&#37; e a s&#237;ndrome de compartimento os 8&#8208;14&#37;<a class="elsevierStyleCrossRefs" href="#bib0200"><span class="elsevierStyleSup">8&#44;12&#44;16&#44;18&#8211;20</span></a>&#46;</p><p id="par0275" class="elsevierStylePara elsevierViewall">Tal como na meta&#8208;an&#225;lise de Cheng et al&#46;&#44; a IRA foi a complica&#231;&#227;o mais frequentemente associada a este suporte&#44; atingido na nossa s&#233;rie mais de 75&#37; dos doentes em ECMO&#8208;VA e quase 40&#37; em ECMO&#8208;VV<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">20</span></a>&#46; A velocidade da bomba e a amplitude de distribui&#231;&#227;o de gl&#243;bulos rubros foram recentemente identificados como preditores do desenvolvimento de IRA<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">21</span></a>&#46; Dez doentes com ECMO&#8208;VA e um doente com ECMO&#8208;VV necessitaram de TSR&#46; Apesar da necessidade de TSR refletir a inadequada perfus&#227;o do rim e&#47;ou a sua les&#227;o direta pelo suporte &#40;hem&#243;lise&#44; transfus&#245;es&#44; rabdomi&#243;lise&#41;&#44; na nossa coorte&#44; o uso de TSR n&#227;o se associou&#44; significativamente&#44; a maior mortalidade em nenhum dos grupos&#46; A dimens&#227;o da amostra poder&#225; explicar este facto&#44; uma vez que diversas s&#233;ries j&#225; demonstraram que a IRA e o uso de TSR s&#227;o preditores independentes de mortalidade nos indiv&#237;duos em ECMO<a class="elsevierStyleCrossRefs" href="#bib0190"><span class="elsevierStyleSup">6&#44;11&#44;19&#44;22&#44;23</span></a>&#46; O grupo ECMO&#8208;VV teve mortalidade hospitalar de 36&#44;8&#37; e o grupo ECMO&#8208;VA 62&#44;1&#37;&#46; Estes resultados s&#227;o consistentes com os observados pelo registo internacional do ELSO&#44; onde os indiv&#237;duos adultos tiveram uma mortalidade hospitalar de 42&#37; no ECMO&#8208;VV e de 59&#37; no ECMO&#8208;VA<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">24</span></a>&#46; Importa referir que 69&#37; dos doentes em ECMO&#8208;VA e 78&#44;9&#37; dos em ECMO&#8208;VV foram descanulados com sucesso&#46;</p><p id="par0280" class="elsevierStylePara elsevierViewall">Na &#225;rea do ECMO&#8208;VV&#44; o <span class="elsevierStyleItalic">CESAR trial</span> foi o primeiro estudo aleatorizado a mostrar claros benef&#237;cios do ECMO&#8208;VV&#46; Este estudo de 180 doentes com insufici&#234;ncia respirat&#243;ria grave aleatorizou doentes para estrat&#233;gia conservadora ou para transfer&#234;ncia para um centro com ECMO&#44; 63&#37; destes &#40;contra 47&#37; no controlo&#41; sobreviveram<a class="elsevierStyleCrossRef" href="#bib0285"><span class="elsevierStyleSup">25</span></a>&#46; Foi em 2009&#44; com a pandemia do H1N1&#44; que a maioria dos centros melhorou a sua experi&#234;ncia com o ECMO<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">26</span></a>&#46; No nosso centro&#44; dos cinco doentes com SDRA secund&#225;ria a infe&#231;&#227;o por H1N1 todos sobreviveram&#46;</p><p id="par0285" class="elsevierStylePara elsevierViewall">Na an&#225;lise univariada&#44; verificamos que no ECMO&#8208;VV n&#227;o foram encontrados preditores de mortalidade&#59; noutras s&#233;ries j&#225; publicadas a exist&#234;ncia de patologia pulmonar pr&#233;via&#44; a idade avan&#231;ada&#44; a exist&#234;ncia pr&#233;via de barotrauma e o n&#250;mero de dias em VMI pr&#233;via ao ECMO s&#227;o preditores independentes de mortalidade<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">13&#44;27&#44;28</span></a>&#46;</p><p id="par0290" class="elsevierStylePara elsevierViewall">No ECMO&#8208;VA&#44; o n&#250;mero superior de agentes inotr&#243;picos utilizados durante o internamento foi preditor de mortalidade&#46; Noutras s&#233;ries j&#225; publicadas&#44; s&#227;o preditores independentes de mortalidade&#58; a idade avan&#231;ada&#44; sexo feminino&#44; &#237;ndice de massa corporal elevado&#44; diabetes <span class="elsevierStyleItalic">mellitus</span>&#44; lactato s&#233;rico elevado&#44; n&#250;mero de unidades de GR transfundidas e coloca&#231;&#227;o do ECMO em PCR<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">3&#44;6&#44;18&#44;23&#44;29&#44;32</span></a>&#46;</p><p id="par0295" class="elsevierStylePara elsevierViewall">Quando se avalia a mortalidade&#44; tendo em conta o motivo de coloca&#231;&#227;o de dispositivo&#44; verifica&#8208;se que o choque cardiog&#233;nico p&#243;s&#8208;EAM e o choque p&#243;s&#8208;cardiotomia t&#234;m a mortalidade mais elevada&#44; reportando a maioria das s&#233;ries valores de 40&#8208;75&#37;<a class="elsevierStyleCrossRefs" href="#bib0250"><span class="elsevierStyleSup">18&#44;29&#8211;32</span></a>&#46; Na nossa amostra&#44; estes doentes tiveram uma mortalidade de 77&#37;&#46; Nestas s&#233;ries&#44; a coloca&#231;&#227;o do ECMO neste contexto ocorreu maioritariamente antes ou durante o procedimento de revasculariza&#231;&#227;o percut&#226;nea&#44; enquanto&#44; no nosso caso&#44; s&#243; foi colocado o suporte ventricular&#44; quando&#44; ap&#243;s a interven&#231;&#227;o percut&#226;nea bem&#8208;sucedida&#44; o doente mantinha choque cardiog&#233;nico refrat&#225;rio&#44; refletindo&#44; neste caso&#44; fal&#234;ncia de bomba&#44; e provavelmente menor potencial de recupera&#231;&#227;o&#46;</p><p id="par0300" class="elsevierStylePara elsevierViewall">Tendo em conta os custos elevados deste suporte e a alta mortalidade a curto&#8208;prazo&#44; &#233; vital a sele&#231;&#227;o criteriosa de doentes&#46; Shmidt et al&#46; publicaram em 2015 o SAVE&#8208;<span class="elsevierStyleItalic">score</span>&#44; que tem como objetivo prever a sobreviv&#234;ncia ap&#243;s ECMO&#8208;VA<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">5</span></a>&#46; Na nossa amostra&#44; o SAVE&#8208;<span class="elsevierStyleItalic">score</span> m&#233;dio foi de &#8208;4&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;9 e a mediana foi de &#8208;4&#44;5 &#40;IQR &#8208;0&#44;25&#47;&#8208;8&#41;&#46; Assim&#44; a maioria dos nossos doentes estaria na classe de risco III a IV&#44; com sobreviv&#234;ncias estimadas de 30&#8208;42&#37;&#44; o que corresponde de facto &#224; sobreviv&#234;ncia observada de 37&#44;9&#37;&#46; Este <span class="elsevierStyleItalic">score</span> carece ainda de valida&#231;&#227;o&#44; mas poder&#225; ser uma ferramenta muito &#250;til no futuro<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">5</span></a>&#46;</p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Limita&#231;&#245;es</span><p id="par0305" class="elsevierStylePara elsevierViewall">As limita&#231;&#245;es do nosso trabalho devem ser vistas no contexto do seu <span class="elsevierStyleItalic">design</span>&#46; &#201; um estudo de coorte&#44; retrospetivo e sem utiliza&#231;&#227;o de grupo de controlo&#46; O tamanho da amostra e a inclus&#227;o de algumas vari&#225;veis que os autores consideraram importantes foi impossibilitada pelo registo insuficiente de alguns dados&#46; Poder&#227;o&#44; assim&#44; existir vieses que podem ter influenciado os resultados apresentados&#46; Por outro lado&#44; este &#233; um registo de um &#250;nico centro e&#44; portanto&#44; a generaliza&#231;&#227;o dos resultados &#233; limitada&#46;</p><p id="par0310" class="elsevierStylePara elsevierViewall">Apesar disto&#44; este &#233; um estudo que mostra os resultados do mundo real&#44; de um hospital terci&#225;rio na utiliza&#231;&#227;o do ECMO&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Conclus&#227;o</span><p id="par0315" class="elsevierStylePara elsevierViewall">Os doentes com fal&#234;ncia cardiovascular&#44; que colocam ECMO&#8208;VA&#44; t&#234;m mortalidade muito superior &#224; dos doentes com fal&#234;ncia respirat&#243;ria&#44; que colocam ECMO&#8208;VV&#46; No ECMO&#8208;VV a implanta&#231;&#227;o mais tardia do dispositivo parece associar&#8208;se a pior progn&#243;stico&#46;</p><p id="par0320" class="elsevierStylePara elsevierViewall">As complica&#231;&#245;es foram relativamente comuns&#44; particularmente as vasculares&#46; Associadas &#224; disfun&#231;&#227;o hematol&#243;gica e ao dif&#237;cil equil&#237;brio na hem&#243;stase&#44; as estrat&#233;gicas que visam minimizar as suas consequ&#234;ncias s&#227;o priorit&#225;rias no manejo destes doentes&#46;</p><p id="par0325" class="elsevierStylePara elsevierViewall">No ECMO&#8208;VA&#44; a necessidade de mais f&#225;rmacos inotr&#243;picos foi preditor de mortalidade&#46;</p><p id="par0330" class="elsevierStylePara elsevierViewall">Podemos concluir que&#44; apesar da pequena amostra apresentada&#44; os resultados alcan&#231;ados s&#227;o semelhantes aos publicados pela maioria das s&#233;ries&#46; Este &#233; o primeiro registo publicado que demonstra os resultados globais da experi&#234;ncia com ECMO num hospital terci&#225;rio&#44; em Portugal&#46;</p></span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">Responsabilidades &#233;ticas</span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">Prote&#231;&#227;o de pessoas e animais</span><p id="par0335" class="elsevierStylePara elsevierViewall">Os autores declaram que para esta investiga&#231;&#227;o n&#227;o se realizaram experi&#234;ncias em seres humanos e&#47;ou animais&#46;</p></span><span id="sec0080" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0140">Confidencialidade dos dados</span><p id="par0340" class="elsevierStylePara elsevierViewall">Os autores declaram que n&#227;o aparecem dados de pacientes neste artigo&#46;</p></span><span id="sec0085" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0145">Direito &#224; privacidade e consentimento escrito</span><p id="par0345" class="elsevierStylePara elsevierViewall">Os autores declaram que n&#227;o aparecem dados de pacientes neste artigo&#46;</p></span></span><span id="sec0090" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0150">Conflito de interesses</span><p id="par0350" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflito de interesses&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introdu&#231;&#227;o</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A oxigena&#231;&#227;o por membrana extracorporal &#40;ECMO&#41; permite o suporte mec&#226;nico em doentes com fal&#234;ncia cardiovascular e&#47;ou pulmonar&#46; Neste estudo pretendemos descrever as indica&#231;&#245;es&#44; caracter&#237;sticas cl&#237;nicas&#44; complica&#231;&#245;es e mortalidade associadas ao uso de ECMO num hospital terci&#225;rio&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">M&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Foi realizado um estudo de coorte retrospetivo e observacional de todos os doentes que implantaram ECMO&#44; em duas unidades de cuidados intensivos &#40;polivalente e card&#237;aca&#41;&#44; desde o primeiro doente canulado em abril&#47;2011 at&#233; outubro&#47;2016&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Quarenta e oito doentes colocaram ECMO&#58; 29 ECMO venoarterial &#40;ECMO&#8208;VA&#41; e 19 ECMO venovenoso &#40;ECMO&#8208;VV&#41;&#46; No ECMO&#8208;VA&#44; o enfarte agudo do mioc&#225;rdio foi a principal indica&#231;&#227;o para a sua implanta&#231;&#227;o&#46; A complica&#231;&#227;o mais frequente foi a isquemia do membro inferior e a disfun&#231;&#227;o de &#243;rg&#227;o associada mais comum foi a renal&#46; No ECMO&#8208;VV&#44; a s&#237;ndrome de dificuldade respirat&#243;ria aguda secund&#225;ria a infe&#231;&#227;o viral foi o motivo dominante para a utiliza&#231;&#227;o do dispositivo&#46; A hemorragia pelo local de acesso e a disfun&#231;&#227;o hematol&#243;gica foram&#44; respetivamente&#44; a complica&#231;&#227;o e a disfun&#231;&#227;o de &#243;rg&#227;o mais prevalentes&#46; Foram descanulados com sucesso quase 70&#37; dos doentes&#44; em ambos os grupos&#46; Os doentes em ECMO&#8208;VA tiveram sobreviv&#234;ncia hospitalar de 37&#44;9&#37; e os em ECMO&#8208;VV 63&#44;2&#37;&#46; O n&#250;mero de agentes inotr&#243;picos foi preditor de mortalidade no ECMO&#8208;VA&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclus&#227;o</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Os doentes que colocaram ECMO ap&#243;s fal&#234;ncia respirat&#243;ria tiveram sobreviv&#234;ncia superior aos que colocaram ap&#243;s fal&#234;ncia card&#237;aca&#46; No ECMO&#8208;VA&#44; a necessidade de mais f&#225;rmacos inotr&#243;picos foi preditor de mortalidade&#46; Este &#233; o primeiro registo publicado com a experi&#234;ncia global com ECMO num hospital terci&#225;rio&#44; em Portugal&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introduction</span><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Extracorporeal membrane oxygenation &#40;ECMO&#41; provides mechanical pulmonary and circulatory support for patients with shock refractory to conventional medical therapy&#46; In this study we aim to describe the indications&#44; clinical characteristics&#44; complications and mortality associated with use of ECMO in a single tertiary hospital&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Methods</span><p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">We conducted a retrospective observational cohort study of all patients supported with ECMO in two different intensive care units &#40;general and cardiac&#41;&#44; from the first patient cannulated in April 2011 up to October 2016&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Results</span><p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">Overall&#44; 48 patients underwent ECMO&#58; 29 venoarterial ECMO &#40;VA&#8208;ECMO&#41; and 19 venovenous ECMO &#40;VV&#8208;ECMO&#41;&#46; In VA&#8208;ECMO&#44; acute myocardial infarction was the main reason for placement&#46; The most frequent complication was lower limb ischemia and the most common organ dysfunction was acute renal failure&#46; In VV&#8208;ECMO&#44; acute respiratory distress syndrome after viral infection was the leading reason for device placement&#46; Access site bleeding and hematologic dysfunction were the most prevalent complication and organ dysfunction&#44; respectively&#46; Almost 70&#37; of ECMO episodes were successfully weaned in each group&#46; Survival to discharge was 37&#46;9&#37; for VA&#8208;ECMO and 63&#46;2&#37; for VV&#8208;ECMO&#46; In VA&#8208;ECMO&#44; the number of inotropic agents was a predictor of mortality&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusion</span><p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">Patients with respiratory indications for ECMO experienced better survival than cardiac patients&#46; The need for more inotropic drugs was a predictor of mortality in VA&#8208;ECMO&#46; This is the first published record of the overall experience with ECMO in a Portuguese tertiary hospital&#46;</p></span>"
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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Indica&#231;&#227;o prim&#225;ria para a coloca&#231;&#227;o da oxigena&#231;&#227;o por membrana extracorporal e mortalidade&#44; &#8224; &#8208; morte&#46; ECMO&#58; oxigena&#231;&#227;o por membrana extracorporal&#59; ECMO&#8208;VV&#58; oxigena&#231;&#227;o por membrana extracorporal venovenoso&#59; ECMO&#8208;VA&#58; oxigena&#231;&#227;o por membrana extracorporal venoarterial&#59; EAM&#58; enfarte agudo do mioc&#225;rdio&#59; IC&#58; insufici&#234;ncia card&#237;aca&#59; SDRA&#58; s&#237;ndrome de dificuldade respirat&#243;ria aguda&#46;</p>"
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                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Caracter&#237;sticas gerais</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Idade &#40;anos&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">51&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;355&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sexo masculino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15&#47;51&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#47;52&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;951&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Comorbilidades &#40;&#37;&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertens&#227;o arterial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#47;48&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;21&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;057&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dislipidemia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15&#47;51&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#47;31&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;169&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diabetes <span class="elsevierStyleItalic">mellitus</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5&#47;17&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;21&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tabagismo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">16&#47;55&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#47;36&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;214&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Doen&#231;a coron&#225;ria&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;13&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;142&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Fatores pr&#233;&#8208;ECMO</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Outro hospital&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12&#47;41&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;5&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;006&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo de diagn&#243;stico at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">50&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>85&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">227&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>245&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;007&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo admiss&#227;o at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>85&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">226&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>244&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo VMI at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">9&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>15&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">110&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>137&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>PCR &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">13&#47;44&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;5&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo retorno circula&#231;&#227;o &#40;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>FC &#40;bpm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">112&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>33&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">103&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>22&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;378&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>PAm &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">62&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">68&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>pO<span class="elsevierStyleInf">2</span> &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">89&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>80&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">61&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>16&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;179&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>pCO<span class="elsevierStyleInf">2</span> &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">39&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">53&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>22&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;061&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lactatos &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>K &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;079&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Leuc&#243;citos &#40;x<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleSup">3</span>&#47;uL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">16&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;298&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bicarbonato &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">24&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Creatinina &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;064&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>TFG<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>60<span class="elsevierStyleHsp" style=""></span>mL&#47;min&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21&#47;72&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#47;36&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;015&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemat&#243;crito &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">34&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">32&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;460&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Plaquetas &#40;x<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleSup">3</span>&#47;uL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">191&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>102&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">223&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>190&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;463&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>AST &#40;U&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1253&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1844&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">159&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>194&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;020&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bilirrubina total &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;345&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Complica&#231;&#245;es</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>IRA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22&#47;75&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#47;36&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;007&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemofiltra&#231;&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#47;34&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;5&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;032&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Disfun&#231;&#227;o hematol&#243;gica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17&#47;58&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">13&#47;68&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;167&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Disfun&#231;&#227;o hep&#225;tica&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">9&#47;47&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;518&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#46;&#176; UGR &#40;unidade&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;556&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#46;&#176; PFC &#40;unidade&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;120&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#46;&#176; plaq &#40;unidade&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>16&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;445&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Complica&#231;&#227;o do acesso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;10&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;15&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;669&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemorragia do acesso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;6&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;21&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;197&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Isquemia do membro&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;068&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;ndrome de compartimento&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;267&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemorragia cerebral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;3&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemorragia gastrointestinal&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;5&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">263&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>153&#44;2&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">40&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">9&#47;31&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;21&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;087&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;447&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Comorbilidades &#40;&#37;&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertens&#227;o arterial&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dislipidemia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#47;63&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#47;44&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;316&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diabetes <span class="elsevierStyleItalic">mellitus</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;9&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;22&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;364&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tabagismo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5&#47;45&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#47;61&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;411&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Doen&#231;a coron&#225;ria&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;9&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;16&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Fatores pr&#233;&#8208;ECMO</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Outro hospital&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#47;63&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5&#47;27&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;119&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo de diagn&#243;stico at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>36&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">58&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>103&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;526&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo admiss&#227;o at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">53&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>105&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;079&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo VMI at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>15&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>15&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;716&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>PCR &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;36&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">9&#47;50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;702&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo at&#233; retorno circula&#231;&#227;o &#40;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;744&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Motivo de coloca&#231;&#227;o &#8211; EAM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;18&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#47;38&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;412&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>ICP pr&#233;via&#44; se motivo EAM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#47;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>FC &#40;bpm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">113&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>44&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">115&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>27&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;878&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>PAm &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">62&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>16&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">62&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;936&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>pO<span class="elsevierStyleInf">2</span> &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">81&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>26&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">94&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>100&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;707&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>pCO<span class="elsevierStyleInf">2</span> &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">31&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>22&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;127&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lactatos &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;838&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>K &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;148&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Leuc&#243;citos &#40;x<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleSup">3</span>&#47;uL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">13&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;051&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bicarbonato &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;502&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Creatinina &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;749&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>TFG<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>60<span class="elsevierStyleHsp" style=""></span>mL&#47;min&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#47;54&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15&#47;83&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;197&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemat&#243;crito &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">32&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;437&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Plaquetas &#40;x<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleSup">3</span>&#47;uL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">151&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>54&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">217&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>118&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;057&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>AST &#40;U&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1215&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1962&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1278&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1826&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;932&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bilirrubina total &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;846&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Complica&#231;&#245;es</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>IRA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#47;72&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#47;77&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;758&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemofiltra&#231;&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;18&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">9&#47;50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;125&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#46;&#176; UGR &#40;unidade&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;394&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#46;&#176; PFC &#40;unidade&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;235&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#46;&#176; plaq &#40;unidade&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;738&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Complica&#231;&#227;o do acesso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;27&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;045&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemorragia do acesso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;11&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;512&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Isquemia do membro&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;18&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;22&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;ndrome de compartimento&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;18&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;5&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;539&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemorragia cerebral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;5&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemorragia gastrointestinal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;11&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;512&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo de suporte amin&#233;rgico &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">139&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>88&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">172&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>141&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;471&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#46;&#176; de agentes inotr&#243;picos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;004&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Dispositivos de venting do VE</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;286&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BIA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;18&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;16&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Impella CP<span class="elsevierStyleSup">&#174;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;16&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Horas em ECMO</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">116&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>61&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">120&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>125&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;926&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;082&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;42&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;650&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Comorbilidades</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertens&#227;o arterial&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;245&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;14&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;333&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diabetes <span class="elsevierStyleItalic">mellitus</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;14&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tabagismo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;33&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;42&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Fatores pr&#233;&#8208;ECMO</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Outro hospital&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;8&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo de diagn&#243;stico at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">132&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>128&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">390&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>318&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;078&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo admiss&#227;o at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">130&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>124&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">390&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>318&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;076&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo VMI at&#233; ECMO &#40;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">82&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>85&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">168&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>206&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;222&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>PCR&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;8&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tempo at&#233; retorno circula&#231;&#227;o &#40;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>FC &#40;bpm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">98&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">114&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>24&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;197&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>PAm &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">68&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>15&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;655&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>pO<span class="elsevierStyleInf">2</span> &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">61&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">60&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;885&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>pCO<span class="elsevierStyleInf">2</span> &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">56&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>27&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">46&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;297&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lactatos &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#44;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;511&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>K &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;275&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Leuc&#243;citos &#40;x<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleSup">3</span>&#47;uL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;354&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bicarbonato &#40;mmol&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">24&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">23&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;692&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Creatinina &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;611&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>TFG<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>60<span class="elsevierStyleHsp" style=""></span>mL&#47;min&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5&#47;41&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;28&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;656&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemat&#243;crito &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">31&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;311&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Plaquetas &#40;x<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleSup">3</span>&#47;uL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">253&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>222&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">163&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>88&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;362&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>AST &#40;U&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">122&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>74&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">249&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>348&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;461&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bilirrubina total &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;409&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Complica&#231;&#245;es</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>IRA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;33&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#47;42&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemofiltra&#231;&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#47;14&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;368&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#46;&#176; UGR &#40;unidade&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#44;9&nbsp;\t\t\t\t\t\t\n
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