Letter to the Editor
Antiplatelet therapy at discharge for Takotsubo syndrome: Could propensity matching and/or sensitivity analysis be of value? Response
Terapêutica antiplaquetária no momento da alta por síndrome de Takotsubo: pode a combinação do score de propensão e/ou da análise de sensibilidade ser importante? Resposta
Eduardo Pereyra, Silvia González-Sucarrats, Diego Fernández-Rodríguez
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Department of Cardiology, University Hospital Arnau de Vilanova, Institut de Reçerca Biomèdica de Lleida (IRBLleida), Lleida, Spain
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Response" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "599" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Eduardo Pereyra, Silvia González-Sucarrats, Diego Fernández-Rodríguez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Eduardo" "apellidos" => "Pereyra" ] 1 => array:2 [ "nombre" => "Silvia" "apellidos" => "González-Sucarrats" ] 2 => array:4 [ "nombre" => "Diego" "apellidos" => "Fernández-Rodríguez" "email" => array:1 [ 0 => "dfernandez.lleida.ics@gencat.cat" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Department of Cardiology, University Hospital Arnau de Vilanova, Institut de Reçerca Biomèdica de Lleida (IRBLleida), Lleida, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Terapêutica antiplaquetária no momento da alta por síndrome de Takotsubo: pode a combinação do <span class="elsevierStyleItalic">score</span> de propensão e/ou da análise de sensibilidade ser importante? Resposta" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We thank Madias for his positive comments on our article. Regarding the statistical aspects, we agree that performing propensity score matching<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> or posthoc sensitivity analyses<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">2,3</span></a> could have helped to gain a better understanding of the effect of the antiplatelet therapy on the prognosis of patients with Takotsubo syndrome.</p><p id="par0010" class="elsevierStylePara elsevierViewall">With regard to the presence of diabetes and obesity in the Spanish population, data from the 2021 IDF Diabetes Atlas and the Spanish Statistics Office show a prevalence of 14.8% for diabetes and a prevalence of 16.0% for obesity in the overall Spanish population.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">4,5</span></a> These data could exceed 25% in women >70 years.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a> Although the presence of diabetes and obesity could be underrepresented in our population, it is not plausible that the presence of either of these two diseases could have caused bias in any direction in the results, because the parameters for diabetes and obesity are well balanced between the comparison groups (diabetes in the APT at discharge group: 16.5% vs. diabetes in no APT at discharge group: 15.6%, p=0.791; obesity in APT at discharge group: 17% vs. obesity in non-APT at discharge group: 15.7%, p=0.701).</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0015" class="elsevierStylePara elsevierViewall">No funding was received for this work.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0020" class="elsevierStylePara elsevierViewall">None declared.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0035" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Methods for constructing and assessing propensity scores" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "M.M. Garrido" 1 => "A.S. Kelley" 2 => "J. Paris" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/1475-6773.12182" "Revista" => array:6 [ "tituloSerie" => "Health Serv Res" "fecha" => "2014" "volumen" => "49" "paginaInicial" => "1701" "paginaFinal" => "1720" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24779867" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0040" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A tutorial on sensitivity analyses in clinical trials: the what, why, when and how" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "L. Thabane" 1 => "L. Mbuagbaw" 2 => "S. 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López-González" 1 => "J.I. Ramírez Manent" 2 => "M.T. Vicente-Herrero" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.23938/ASSN.0977" "Revista" => array:5 [ "tituloSerie" => "An Sist Sanit Navar" "fecha" => "2022" "volumen" => "45" "paginaInicial" => "e0977" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/34750594" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/08702551/0000004200000006/v1_202306021106/S0870255123002238/v1_202306021106/en/main.assets" "Apartado" => array:4 [ "identificador" => "93494" "tipo" => "SECCION" "pt" => array:2 [ "titulo" => "Letter to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "pt" ] "PDF" => "https://static.elsevier.es/multimedia/08702551/0000004200000006/v1_202306021106/S0870255123002238/v1_202306021106/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255123002238?idApp=UINPBA00004E" ]
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