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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The combination of a sedentary lifestyle and a Western-type &#40;high-calorie&#41; diet is the most important factor contributing to excess body weight&#44; metabolic impairment&#44; and increased risk of developing cardiovascular disease &#40;CVD&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">1</span></a> An estimated 17&#46;9 million people died from CVD worldwide in 2016&#44; representing 31&#37; of all deaths&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">2</span></a> Of these&#44; 85&#37; are due to myocardial infarction and stroke&#46; Moreover&#44; epidemiological and clinical studies have shown an association between maternal malnutrition &#40;under- and overnutrition&#44; including Western-type diets&#41; and the development of cardiovascular and metabolic dysfunction&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The Western-style diet is characterized by highly processed and refined foods and high intakes of sugar&#44; salt&#44; and fat and protein from red meat&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Exercise and diet were important components of ancient medical theory&#46; For example&#44; Hippocrates &#40;c&#46; 460-370 BC&#41; noted that &#8220;eating alone will not keep a man well&#59; he must also take exercise&#46;&#8221;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">5</span></a> Epidemiological studies in large cohorts support the notion that physical fitness is associated with reduced cardiovascular mortality and hospitalization due to CVD&#46; During the last 20 years even the idea that patients should remain inactive after a myocardial infarction has dramatically changed&#44; and nowadays patients are mobilized and included in exercise training programs very shortly after the event&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">6</span></a> Exercise-based cardiac rehabilitation is accordingly given a class IA recommendation for patients with coronary artery disease and heart failure&#46; Aerobic &#40;continuous and&#47;or interval training&#41;&#44; resistance or respiratory muscle training are usually prescribed&#44; depending on patient assessment and needs&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">7</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Combined resistance-endurance training has been shown to be more effective than aerobic endurance training in improving CV fitness&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">8</span></a> Moreover&#44; resistance training alone has also been shown to improve cardiovascular health by reducing resting blood pressure&#44; improving lipoprotein-lipid profiles and&#47;or dyslipidemia&#44; decreasing triglycerides&#44; increasing high-density lipoprotein cholesterol&#44; and improving cardiovascular response to exercise&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">9</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The paper by Santana-Filho et al&#46; published in this issue of the <span class="elsevierStyleItalic">Journal</span><a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a> is thus timely and addresses a hot topic regarding the impact of physical exercise&#44; specifically resistance training&#44; on cardiovascular and metabolic parameters&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The author has no conflicts of interest to declare&#46;</p></span></span>"
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Editorial comment
Heartfelt exercise: Physical exercise gets the cardiovascular system into shape
Sistema cardiovascular em forma com exercício físico
Frederico C. Pereiraa,b
a Institute of Pharmacology and Experimental Therapeutics/IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
b CNC.IBILI-University of Coimbra, Coimbra, Portugal
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