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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We would like to thank Mustafa G&#252;lg&#252;n for his interest in our manuscript&#46; We investigated calcific aortic stenosis and its correlation with a novel inflammatory marker&#44; the lymphocyte&#47;monocyte ratio &#40;LMR&#41;&#46; We found a statistically significant difference in terms of LMR in patients compared with healthy controls and also found an inverse relationship between severity of calcific aortic stenosis and LMR&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Mustafa G&#252;lg&#252;n pointed out that the lymphocyte cell count is affected by various clinical factors such as gender&#44; age&#44; race&#44; time of sampling&#44; physical and psychological stress&#44; pregnancy&#44; drugs&#44; infections&#44; smoking&#44; presence of anti-lymphocyte autoantibodies and procedures such as splenectomy&#46; As we stated in our paper&#44; we excluded patients that had active or chronic infection&#44; systemic inflammatory or allergic disease&#44; and renal&#44; hepatic or hematologic disease&#46; Besides&#44; there were there no significant differences between the groups in terms of age&#44; gender&#44; smoking status or type of drugs used by the participants&#46; All of our patients were Caucasian&#46; In our hospital blood samples are drawn before midday after 10 hours of fasting&#44; and we only used fasting blood samples for study&#46; In addition&#44; all the study participants were aged over 60&#44; and at their age they were unlikely to perform heavy exercise&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">In short&#44; we tried to minimize the factors that could affect lymphocyte counts and other blood parameters&#46; On the other hand&#44; we agree with the author that prospective research into this topic may be useful&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0015" class="elsevierStylePara elsevierViewall">The author has no conflicts of interest to declare&#46;</p></span></span>"
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Letter to the Editor
Reply to the Letter to the Editor “Methodology, as well as physiological and pathological conditions, can affect analysis of the lymphocyte-to-monocyte ratio”
Resposta à Carta ao Editor «A metodologia assim como as condições fisiológica e patológica podem afetar a análise da relação linfócitos/monócitos»
Tolga Han Efea,
Autor para correspondência
medisay@gmail.com

Corresponding author.
, Ahmet Goktug Ertemb, Tolga Cimena
a Department of Cardiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey
b Department of Cardiology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
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ISSN: 08702551
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