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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introdu&#231;&#227;o</span><p id="par0005" class="elsevierStylePara elsevierViewall">A fibrilha&#231;&#227;o auricular &#40;FA&#41; &#233; a arritmia sustentada mais frequente na pr&#225;tica cl&#237;nica&#44; com uma incid&#234;ncia de 19&#44;2 por 1000 doentes&#47;ano&#44; em indiv&#237;duos com idade superior a 65 anos&#46; A FA constitui uma importante causa de morbilidade&#44; quer pela pr&#243;pria condi&#231;&#227;o quer pelo risco associado de acidente vascular cerebral &#40;AVC&#41; tromboemb&#243;lico&#44; tendo&#8208;se comprovado ser um fator de risco independente tanto para a mortalidade global&#44; como para a morte s&#250;bita de causa card&#237;aca<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">1</span></a>&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">No estudo Framingham&#44; o risco anual de AVC imput&#225;vel &#224; FA foi de 1&#44;5&#37;&#44; em doentes com idades entre 50&#8208;59 anos&#44; aumentando de forma exponencial para 23&#44;5&#37; em doentes com mais de 80 anos de idade<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">2</span></a>&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">A incid&#234;ncia e mortalidade por AVC apresentam&#44; em Portugal&#44; valores mais elevados do que na maioria dos pa&#237;ses europeus&#46; Calcula&#8208;se que a incid&#234;ncia anual de AVC seja t&#227;o elevada como 3&#44;05 por 1000 habitantes em zonas rurais do norte de Portugal ou 2&#44;69 por 1000 na zona urbana do grande Porto&#44; incid&#234;ncia que &#233; superior &#224; m&#233;dia europeia&#44; n&#227;o podendo esses valores ser atribu&#237;dos apenas aos outros fatores de risco conhecidos para essa situa&#231;&#227;o neurol&#243;gica<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">3</span></a>&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Uma poss&#237;vel explica&#231;&#227;o poderia ser a exist&#234;ncia de uma preval&#234;ncia concomitantemente mais elevada de FA na popula&#231;&#227;o portuguesa&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Este foi o racional para a realiza&#231;&#227;o do estudo FAMA Epidemiol&#243;gico &#40;Estudo de Avalia&#231;&#227;o da Preval&#234;ncia de Fibrilha&#231;&#227;o Auricular em Portugal&#41;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">4</span></a>&#44; que incluiu 10<span class="elsevierStyleHsp" style=""></span>447 indiv&#237;duos e fixou a preval&#234;ncia de FA em Portugal em 2&#44;5&#37;&#44; numa popula&#231;&#227;o com 40 ou mais anos de idade&#44; indiferente ao g&#233;nero ou &#225;rea geogr&#225;fica&#46; Esta preval&#234;ncia &#233;&#44; sem d&#250;vida&#44; muito mais elevada em doentes entre os 70&#8208;79 anos de idade&#44; atingindo nesta d&#233;cada os 6&#44;6&#37; e os 10&#44;4&#37; em doentes com mais de 80 anos&#46; &#201;&#44; contudo&#44; baixa em doentes com idade inferior&#44; sendo de 1&#44;6&#37; para doentes com 60&#8208;69 anos de idade&#46; Neste estudo&#44; o diagn&#243;stico de FA foi efetuado atrav&#233;s da realiza&#231;&#227;o de um eletrocardiograma &#40;ECG&#41; de 12 deriva&#231;&#245;es&#44; tendo a amostra sido definida por um m&#233;todo aleat&#243;rio de visita domicili&#225;ria&#44; em todo o territ&#243;rio nacional&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">A preval&#234;ncia encontrada no estudo FAMA Epidemiol&#243;gico &#233; superior ao esperado relativamente a estudos anteriores realizados na popula&#231;&#227;o portuguesa&#44; mas &#233; inferior a estudos realizados na Europa e que serviram de refer&#234;ncia para esse estudo<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">5</span></a>&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">No estudo de Roterd&#227;o&#44; realizado entre 1990&#8208;2000&#44; que incluiu 7983 pessoas com 55 anos ou mais &#40;idade m&#233;dia 69&#44;3 anos&#41;&#44; avaliadas com recurso &#224; realiza&#231;&#227;o de um ECG de 12 deriva&#231;&#245;es&#44; os valores de preval&#234;ncia apresentados foram de 5&#44;5&#37; para a avalia&#231;&#227;o basal&#46; Considerando estes resultados e a distribui&#231;&#227;o por sexo e idade da popula&#231;&#227;o portuguesa em 2009&#44; poderia ser feita uma estimativa da preval&#234;ncia na ordem dos 3&#44;8&#37; acima dos 45 anos e dos 6&#44;8&#37; acima dos 60 anos<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">5</span></a>&#46; Esta discrep&#226;ncia pode ser atribu&#237;da ao facto de esta amostra estar confinada a uma &#225;rea geogr&#225;fica restrita&#44; enquanto no estudo FAMA foi considerada uma amostra muito ampla&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Uma limita&#231;&#227;o do estudo FAMA<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">4</span></a> &#233; a avalia&#231;&#227;o de ritmo num curto per&#237;odo de tempo&#44; pelo que a FA&#44; se parox&#237;stica&#44; &#233; necessariamente subavaliada&#46; Com a realiza&#231;&#227;o deste estudo ficou a ideia de que a FA &#233; subdiagnosticada e subtratada&#46; Isto ser&#225; muito mais verdade se considerarmos a FA parox&#237;stica &#40;FAP&#41;&#44; para a qual se estima uma preval&#234;ncia&#44; pelo menos&#44; tr&#234;s vezes superior &#224; FA persistente &#40;an&#225;lise n&#227;o sistematizada da pr&#225;tica cl&#237;nica&#41;&#46; Na verdade&#44; as estimativas da preval&#234;ncia da FAP existentes s&#227;o escassas&#44; referindo&#8208;se essencialmente &#224;s formas sintom&#225;ticas &#8211; cerca de 50&#37; no estudo de Framingham<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">3&#44;4</span></a> e 35&#8208;60&#37; noutros estudos&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">A monitoriza&#231;&#227;o cont&#237;nua de 24 horas &#40;por m&#233;todo Holter&#41; &#233; um exame utilizado por rotina na avalia&#231;&#227;o de sintomatologia variada&#44; mas especialmente na avalia&#231;&#227;o de palpita&#231;&#245;es&#46; &#201; usado frequentemente para avaliar o perfil de frequ&#234;ncia card&#237;aca em doentes com FA conhecida e para avaliar a efic&#225;cia da manuten&#231;&#227;o de ritmo sinusal com antiarr&#237;tmicos ou ap&#243;s abla&#231;&#227;o por cateter&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Embora o Holter seja&#44; sem d&#250;vida&#44; melhor na avalia&#231;&#227;o da preval&#234;ncia de FA do que o ECG de 12 deriva&#231;&#245;es&#44; pois permite avaliar situa&#231;&#245;es de paroxismos di&#225;rios&#44; que de outra forma n&#227;o seriam detetados&#44; &#233; ainda assim um m&#233;todo que estimar&#225; esta preval&#234;ncia por defeito&#46; Por outro lado&#44; por si s&#243;&#44; n&#227;o pode fazer uma distin&#231;&#227;o definitiva entre FA persistente &#40;<span class="elsevierStyleItalic">persistent</span>&#41; e persistente de longa dura&#231;&#227;o &#40;<span class="elsevierStyleItalic">long&#8208;standing persistent</span>&#41;&#44; entidades definidas como distintas nas <span class="elsevierStyleItalic">Guidelines</span> da ESC<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">6</span></a>&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Decorre ainda da defini&#231;&#227;o de FAP&#44; aquela que reverte espontaneamente em menos de 48 horas&#44; que a monitoriza&#231;&#227;o apenas de 24 horas pode considerar como persistente uma FA que &#233;&#44; na realidade&#44; parox&#237;stica&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">O Holter&#44; ao realizar um registo eletrocardiogr&#225;fico prolongado &#233; um m&#233;todo que permite um estudo mais aprofundado da preval&#234;ncia da FA&#44; permitindo detetar indiv&#237;duos que t&#234;m paroxismos di&#225;rios e que est&#227;o t&#227;o sujeitos a tromboembolismo como aqueles que t&#234;m FA mantida&#44; assumindo&#8208;se o mesmo <span class="elsevierStyleItalic">score</span> de risco&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">O Holter de 12 deriva&#231;&#245;es&#44; utilizado neste estudo&#44; tem vantagens sobre o tradicional Holter de tr&#234;s deriva&#231;&#245;es&#44; pois permite uma an&#225;lise t&#227;o cuidada da situa&#231;&#227;o de ritmo como a efetuada num ECG de 12 deriva&#231;&#245;es&#44; com a vantagem de se poder analisar o in&#237;cio e fim do epis&#243;dio&#44; passagem entre FA e <span class="elsevierStyleItalic">flutter</span> auricular &#40;FLA&#41; ou definir epis&#243;dios de taquicardia auricular&#44; situa&#231;&#227;o que &#233; muitas vezes confundida com a de FA&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">&#201; poss&#237;vel no Holter de 12 deriva&#231;&#245;es utilizar defini&#231;&#245;es de FA e FLA id&#234;nticas &#224;s usadas no ECG de 12 deriva&#231;&#245;es&#44; a saber&#58;</p><p id="par0075" class="elsevierStylePara elsevierViewall">FA&#44; arritmia caracterizada pela completa irregularidade dos intervalos RR&#44; com oscila&#231;&#227;o aleat&#243;ria da linha de base com aus&#234;ncia de ondas P&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Por sua vez&#44; a forma mais frequente de FLA&#44; designada como &#171;t&#237;pica&#187;&#44; &#233; caraterizada por ondas F bif&#225;sicas predominantemente negativas nas deriva&#231;&#245;es inferiores&#44; com padr&#227;o &#171;dentes de serra&#187; e ondas F predominantemente positivas em v1&#46; O FLA at&#237;pico corresponde aos que n&#227;o apresentam a morfologia anteriormente descrita<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">7</span></a>&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">O exame Holter &#233; inclu&#237;do em muitos casos&#44; por rotina&#44; na avalia&#231;&#227;o cardiol&#243;gica antes de uma avalia&#231;&#227;o por cardiologista ou independentemente desta&#46; Assim&#44; se considerarmos os indiv&#237;duos que realizam Holter por indica&#231;&#227;o do m&#233;dico de fam&#237;lia&#44; constituem uma popula&#231;&#227;o relativamente pr&#243;xima da popula&#231;&#227;o geral&#44; pois&#44; neste caso&#44; o leque de motivos &#233; muito alargado&#44; tornando menores os vieses de sele&#231;&#227;o e possibilitando a utiliza&#231;&#227;o desta popula&#231;&#227;o para realiza&#231;&#227;o de um estudo de estimativa de preval&#234;ncia&#44; que possa dar indica&#231;&#245;es v&#225;lidas e transpon&#237;veis para a popula&#231;&#227;o em geral&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">O presente estudo visa avaliar a preval&#234;ncia de FAP e&#44; por meio dos seus resultados&#44; poder&#8208;se&#8208;&#225; prestar um importante contributo para a defini&#231;&#227;o de estrat&#233;gias de preven&#231;&#227;o e tratamento da FA em Portugal&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Objetivos</span><p id="par0095" class="elsevierStylePara elsevierViewall">Estudo prospetivo que tem como objetivo principal o c&#225;lculo da preval&#234;ncia da FAP em doentes com 40 ou mais anos de idade&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">Como objetivos secund&#225;rios consideram&#8208;se o c&#225;lculo da preval&#234;ncia total de FA e FLA&#44; independentemente do tipo&#44; e a compara&#231;&#227;o entre as popula&#231;&#245;es com FA&#44; FAP e a popula&#231;&#227;o geral&#44; submetida a monitoriza&#231;&#227;o cont&#237;nua por Holter de 12 deriva&#231;&#245;es durante 24 horas&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Crit&#233;rios de inclus&#227;o&#58;<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">&#8226;</span><p id="par0110" class="elsevierStylePara elsevierViewall">indiv&#237;duos de ambos os sexos&#44; com idade igual ou superior a 40 anos&#59;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">&#8226;</span><p id="par0115" class="elsevierStylePara elsevierViewall">indiv&#237;duos que realizaram monitoriza&#231;&#227;o eletrocardiogr&#225;fica cont&#237;nua e com 12 deriva&#231;&#245;es nos centros selecionados&#44; durante o per&#237;odo de estudo e independente da indica&#231;&#227;o para o exame&#59;</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">&#8226;</span><p id="par0120" class="elsevierStylePara elsevierViewall">consentimento informado escrito&#44; datado e assinado&#46;</p></li></ul></p><p id="par0125" class="elsevierStylePara elsevierViewall">Crit&#233;rios de exclus&#227;o&#58;<ul class="elsevierStyleList" id="lis0010"><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">&#8226;</span><p id="par0130" class="elsevierStylePara elsevierViewall">indiv&#237;duos que&#44; no momento de execu&#231;&#227;o do exame e por decis&#227;o dos colaboradores da equipa de estudo&#44; por qualquer motivo&#44; n&#227;o reunissem condi&#231;&#245;es para a inclus&#227;o no mesmo&#59;</p></li><li class="elsevierStyleListItem" id="lsti0025"><span class="elsevierStyleLabel">&#8226;</span><p id="par0135" class="elsevierStylePara elsevierViewall">recusa em assinar o consentimento informado&#46;</p></li></ul></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Material e m&#233;todos</span><p id="par0140" class="elsevierStylePara elsevierViewall">Estudo epidemiol&#243;gico&#44; transversal e prospetivo&#44; que incluiu indiv&#237;duos com indica&#231;&#227;o para realiza&#231;&#227;o de exame Holter&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">Este estudo foi realizado em dois centros de refer&#234;ncia para a realiza&#231;&#227;o de Holter&#44; incluindo uma zona de recolha numa &#225;rea geogr&#225;fica condizente com Douro Litoral e Beira Litoral&#44; onde se inclui toda a zona urbana do grande Porto&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">Os indiv&#237;duos analisados procuraram por iniciativa pr&#243;pria um destes centros para realiza&#231;&#227;o de Holter de 24 horas indicado e requisitado pelo seu m&#233;dico de fam&#237;lia&#44; e foram avaliados e inclu&#237;dos no estudo&#44; independentemente do motivo de pedido de realiza&#231;&#227;o do exame&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">Foram analisados os registos referentes aos indiv&#237;duos que cumpriram todos os crit&#233;rios de inclus&#227;o e n&#227;o apresentaram qualquer crit&#233;rio de exclus&#227;o&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">Todos os indiv&#237;duos preencheram uma declara&#231;&#227;o escrita de consentimento informado&#46;</p><p id="par0165" class="elsevierStylePara elsevierViewall">Os exames de Holter foram efetuados por t&#233;cnicos especializados com forma&#231;&#227;o e treino para o efeito&#44; pertencentes aos centros participantes&#46;</p><p id="par0170" class="elsevierStylePara elsevierViewall">O procedimento de realiza&#231;&#227;o de Holter foi protocolado e realizado de igual forma nos dois centros&#44; tendo sido realizado um Holter de 12 deriva&#231;&#245;es e de 24 horas&#44; sendo que estes laborat&#243;rios privados ofereceram ambos o mesmo padr&#227;o de qualidade com aparelhos de 12 deriva&#231;&#245;es MORTARA&#44; com registadores digitais de mem&#243;ria s&#243;lida&#44; estando a responsabilidade da revis&#227;o e valida&#231;&#227;o do exame centralizada em tr&#234;s arritmologistas e a leitura em dois t&#233;cnicos de cardiopneumonologia experientes&#46;</p><p id="par0175" class="elsevierStylePara elsevierViewall">A cada participante foi ainda aplicado um question&#225;rio relativo a informa&#231;&#227;o demogr&#225;fica&#44; hist&#243;ria cl&#237;nica&#44; sintomatologia e medica&#231;&#227;o&#46;</p><p id="par0180" class="elsevierStylePara elsevierViewall">Os dados foram registados pelos t&#233;cnicos participantes no estudo numa base de dados constru&#237;da para o efeito&#44; pela Keypoint&#44; Consultoria Cient&#237;fica&#44; Lda&#46; Esta base de dados permitiu que os tra&#231;ados do Holter fossem revistos de forma semiautom&#225;tica ou manualmente por tr&#234;s arritmologistas&#44; de forma independente e de forma cega para todos os dados relativos ao paciente&#44; sendo o diagn&#243;stico registado na mesma base de dados&#46; No caso de as avalia&#231;&#245;es dos dois primeiros arritmologistas terem sido distintas&#44; a base de dados notificava automaticamente o terceiro para proceder &#224; valida&#231;&#227;o destas avalia&#231;&#245;es&#46;</p><p id="par0185" class="elsevierStylePara elsevierViewall">Para defini&#231;&#227;o de FA foram utilizados os crit&#233;rios eletrocardiogr&#225;ficos habituais descritos acima e definido como epis&#243;dio de FAP aquele com mais de 30 segundos de dura&#231;&#227;o&#44; com in&#237;cio e&#47;ou fim durante o tra&#231;ado de 24 horas&#46; Da mesma forma&#44; FA persistente foi considerada como aquela que estava presente e mantida durante as 24 horas do exame&#46;</p><p id="par0190" class="elsevierStylePara elsevierViewall">O estudo foi submetido &#224; Comiss&#227;o Nacional de Prote&#231;&#227;o de Dados &#40;CNPD&#41; e ao conselho de administra&#231;&#227;o de cada centro&#44; para implementa&#231;&#227;o do mesmo&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">An&#225;lise estat&#237;stica</span><p id="par0195" class="elsevierStylePara elsevierViewall">A amostra do estudo foi definida em fun&#231;&#227;o do objetivo principal do mesmo&#44; determina&#231;&#227;o da preval&#234;ncia de FAP&#44; tendo&#8208;se assumido como pressuposto inicial que esta preval&#234;ncia seria&#44; pelo menos&#44; tr&#234;s vezes maior do que a preval&#234;ncia de FA&#44; estimada em 2&#44;5&#37; pelo estudo FAMA&#46;</p><p id="par0200" class="elsevierStylePara elsevierViewall">Foram inclu&#237;dos 4843 indiv&#237;duos&#44; o que permitiu estimar intervalos de confian&#231;a a 95&#37; &#40;IC a 95&#37;&#41;&#44; com um erro amostra de<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;0&#37;&#46;</p><p id="par0205" class="elsevierStylePara elsevierViewall">Foi efetuada uma an&#225;lise estat&#237;stica descritiva para todas as vari&#225;veis em an&#225;lise&#44; tendo sido determinados os IC a 95&#37; para as preval&#234;ncias estimadas&#46; Foi utilizada a m&#233;dia&#44; mediana e desvio padr&#227;o como medidas de descri&#231;&#227;o das vari&#225;veis cont&#237;nuas e a frequ&#234;ncia absoluta e relativa para as vari&#225;veis categ&#243;ricas&#46;</p><p id="par0210" class="elsevierStylePara elsevierViewall">Na compara&#231;&#227;o entre grupos&#44; nomeadamente doentes com e sem FA e com FAP ou FLA <span class="elsevierStyleItalic">versus</span> doentes com FA persistente&#44; foi utilizado o teste de quiquadrado para compara&#231;&#227;o de frequ&#234;ncias relativas e o teste t para amostras independentes para compara&#231;&#227;o de m&#233;dias&#44; uma vez que as vari&#225;veis em an&#225;lise t&#234;m uma distribui&#231;&#227;o normal&#46; Foi considerado um n&#237;vel de signific&#226;ncia de 0&#44;05&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Resultados</span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Caracteriza&#231;&#227;o do perfil da popula&#231;&#227;o analisada</span><p id="par0215" class="elsevierStylePara elsevierViewall">Este estudo analisou um total de 4843 pessoas &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Tabela 1</a>&#41;&#44; 58&#37; dos quais do sexo feminino&#46; Vinte seis v&#237;rgula dois por cento dos quais se encontrava na faixa et&#225;ria dos 70&#8208;79 anos &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1269&#41;&#44; 25&#44;9&#37; &#40;n&#8208;1252&#41; entre os 60&#8208;69 anos&#44; e 19&#44;0&#37; &#40;n&#8208;923&#41; entre os 50&#8208;59 anos&#59; os restantes doentes ou tinham idades superiores a 80 anos &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>712&#44; 14&#44;7&#37;&#41; ou inferiores a 50 &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>686&#44; 14&#44;2&#37;&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0220" class="elsevierStylePara elsevierViewall">A an&#225;lise dos fatores de risco da popula&#231;&#227;o global analisada revelou que 62&#44;0&#37; destes indiv&#237;duos tem diagn&#243;stico de HTA&#44; 46&#44;1&#37; tem diagn&#243;stico de dislipidemia&#44; 15&#44;9&#37; tem diagn&#243;stico de diabetes&#44; 3&#44;2&#37; tem diagn&#243;stico de hipertiroidismo e 4&#44;5&#37; tem diagn&#243;stico de DPOC&#46;</p><p id="par0225" class="elsevierStylePara elsevierViewall">A ocorr&#234;ncia de EAM &#40;Enfarte agudo do mioc&#225;rdio&#41; pr&#233;vio foi registada em 3&#44;4&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>165&#41;<span class="elsevierStyleHsp" style=""></span>da popula&#231;&#227;o analisada&#44; enquanto a ocorr&#234;ncia de AVC pr&#233;vio foi registada em 5&#44;5&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>267&#41;<span class="elsevierStyleHsp" style=""></span>da mesma&#46;</p><p id="par0230" class="elsevierStylePara elsevierViewall">A an&#225;lise da popula&#231;&#227;o global revelou que a maioria dos indiv&#237;duos n&#227;o pratica regularmente exerc&#237;cio f&#237;sico &#40;77&#44;2&#37;&#44; n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3738&#41;&#46; Relativamente a h&#225;bitos tab&#225;gicos e alco&#243;licos&#44; observou&#8208;se que a maioria dos indiv&#237;duos nunca fumou &#40;74&#44;6&#37;&#41; e n&#227;o tem h&#225;bitos alco&#243;licos &#40;60&#44;5&#37;&#41;&#46;</p><p id="par0235" class="elsevierStylePara elsevierViewall">O pedido de Holter foi efetuado para investiga&#231;&#227;o da sintomatologia destes indiv&#237;duos&#44; tais como palpita&#231;&#245;es&#44; fadiga&#44; dispneia&#44; tonturas&#44; s&#237;ncope&#44; confus&#227;o mental&#44; fraqueza ou dificuldade na realiza&#231;&#227;o de exerc&#237;cio f&#237;sico&#44; arritmia&#44; dor tor&#225;cica&#44; mas tamb&#233;m para avalia&#231;&#227;o de extrassistolia e&#47;ou altera&#231;&#245;es eletrocardiogr&#225;ficas&#44; e no contexto de condi&#231;&#245;es como insufici&#234;ncia card&#237;aca congestiva &#40;ICC&#41; ou AVC pr&#233;vio&#46;</p><p id="par0240" class="elsevierStylePara elsevierViewall">O Holter foi pedido para esclarecimento de palpita&#231;&#245;es em 21&#44;0&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1016&#41; dos indiv&#237;duos&#44; de fadiga em 15&#44;4&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>744&#41;&#44; de dispneia em 7&#44;6&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>366&#41;&#44; de tonturas em 1&#44;8&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>524&#41;&#44; de s&#237;ncope em 8&#44;1&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>391&#41;&#44; de confus&#227;o mental em 0&#44;3&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>13&#41;&#44; de ICC em 2&#44;1&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>103&#41;&#44; de AVC logo ap&#243;s a fase aguda em 0&#44;1&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>5&#41;&#44; de arritmia n&#227;o especificada em 1&#44;5&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>71&#41;&#44; de fraqueza ou dificuldade na realiza&#231;&#227;o de exerc&#237;cio f&#237;sico em 19&#44;8&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>958&#41;&#44; de dor tor&#225;cica em 8&#44;1&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>394&#41;&#44; e de extrassistolia e&#47;ou altera&#231;&#245;es eletrocardiogr&#225;ficas em 4&#44;9&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>239&#41;&#46;</p><p id="par0245" class="elsevierStylePara elsevierViewall">&#201; ainda de referir que&#44; independentemente da sintomatologia&#44; 1511 &#40;31&#44;2&#37;&#41; destes indiv&#237;duos efetuaram avalia&#231;&#227;o cardiovascular por indica&#231;&#227;o m&#233;dica&#44; mas sem um motivo cl&#237;nico espec&#237;fico&#46;</p><p id="par0250" class="elsevierStylePara elsevierViewall">Relativamente &#224; medica&#231;&#227;o&#44; foram analisadas dez classes medicamentosas&#58; antiarr&#237;tmicos&#44; inibidores da enzima de convers&#227;o da angiotensina &#40;IECAS&#41;&#47;antagonistas dos recetores da angiotensina II &#40;ARA II&#41;&#44; antidiab&#233;ticos&#44; diur&#233;ticos&#44; betabloqueantes&#44; antagonistas do c&#225;lcio&#44; &#225;cidos gordos polinsaturados &#40;PUFA&#41;&#44; antidislipid&#233;micos&#44; antiagregantes plaquet&#225;rios e hipocoagula&#231;&#227;o oral&#46;</p><p id="par0255" class="elsevierStylePara elsevierViewall">Ao analisar a medica&#231;&#227;o efetuada pelos doentes em algum ponto no tempo&#44; constatou&#8208;se que os IECAS&#47;ARA II foram os medicamentos mais utilizados &#40;48&#44;4&#37;&#41;&#44; seguidos pelos antidislipid&#233;micos &#40;41&#44;5&#37;&#41;&#44; f&#225;rmacos de antiagrega&#231;&#227;o plaquet&#225;ria &#40;28&#44;7&#37;&#41; e betabloqueantes &#40;22&#44;8&#37;&#41;&#44; entre as classes mais representadas &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Tabela 2</a>&#41;&#46; Tamb&#233;m no que diz respeito aos f&#225;rmacos atualmente em curso se verificou que os mais utilizados por estes doentes s&#227;o os IECAS&#47;ARA II &#40;26&#44;7&#37;&#41;&#44; seguidos pelos antidislipid&#233;micos &#40;22&#44;6&#37;&#41;&#44; antiagregantes plaquet&#225;rios &#40;15&#44;0&#37;&#41; e betabloqueantes &#40;11&#44;5&#37;&#41;&#46; A hipocoagula&#231;&#227;o oral tinha sido alguma vez usada em 10&#44;4&#37; dos doentes estudados e&#44; presentemente&#44; era usada por 5&#44;4&#37; dos indiv&#237;duos&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Preval&#234;ncia de fibrilha&#231;&#227;o auricular parox&#237;stica&#44; fibrilha&#231;&#227;o auricular e <span class="elsevierStyleItalic">flutter</span></span><p id="par0260" class="elsevierStylePara elsevierViewall">Entre os indiv&#237;duos referenciados e analisados&#44; registaram&#8208;se 123 com registo de pelo menos um per&#237;odo de FAP num &#250;nico registo de monitoriza&#231;&#227;o cont&#237;nua de 24 horas&#44; o que equivale a uma preval&#234;ncia de 2&#44;5&#37; &#40;IC a 95&#37; 2&#44;1&#8208;3&#44;0&#37;&#41;&#44; na popula&#231;&#227;o estudada com idade igual ou superior a 40 anos nesta amostragem&#46;</p><p id="par0265" class="elsevierStylePara elsevierViewall">A preval&#234;ncia de doentes com FA persistente&#44; durante todo o registo avaliado&#44; em 24 horas na referida popula&#231;&#227;o foi de 9&#44;4&#37; &#40;IC a 95&#37; 8&#44;6&#8208;10&#44;2&#37;&#41; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>454&#41;&#46;</p><p id="par0270" class="elsevierStylePara elsevierViewall">Registaram&#8208;se ainda 39 casos de doentes com FLA t&#237;pico&#44; 14 deles tinham tamb&#233;m FAP e em dois a FA regularizava em <span class="elsevierStyleItalic">flutter</span>&#46; Mas em 23 quer mantido quer parox&#237;stico aparecia isolado&#44; o que corresponde a uma preval&#234;ncia de 0&#44;8&#37; &#40;IC a 95&#37;&#44; 0&#44;6&#8208;1&#44;1&#37;&#41; deste tipo de arritmia na popula&#231;&#227;o estudada&#46;</p><p id="par0275" class="elsevierStylePara elsevierViewall">Tal indica que a preval&#234;ncia de doentes com fibrilha&#231;&#227;o e&#47;ou FLA &#40;FA<span class="elsevierStyleHsp" style=""></span>&#43;<span class="elsevierStyleHsp" style=""></span>FAP<span class="elsevierStyleHsp" style=""></span>&#43;<span class="elsevierStyleHsp" style=""></span>FLA isolado&#41; total &#233; de 12&#44;4&#37;&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Caracteriza&#231;&#227;o dos indiv&#237;duos com fibrilha&#231;&#227;o auricular e compara&#231;&#227;o com a popula&#231;&#227;o sem fibrilha&#231;&#227;o auricular</span><p id="par0280" class="elsevierStylePara elsevierViewall">Na <a class="elsevierStyleCrossRef" href="#tbl0015">Tabela 3</a> apresenta&#8208;se a compara&#231;&#227;o entre indiv&#237;duos com qualquer tipo de FA ou <span class="elsevierStyleItalic">flutter</span> &#40;FA<span class="elsevierStyleHsp" style=""></span>&#43;<span class="elsevierStyleHsp" style=""></span>FAP<span class="elsevierStyleHsp" style=""></span>&#43;<span class="elsevierStyleHsp" style=""></span>FLA&#41; <span class="elsevierStyleItalic">versus</span> a popula&#231;&#227;o em ritmo sinusal durante as 24 horas&#44; ou seja&#44; livre de FA&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0285" class="elsevierStylePara elsevierViewall">Ao comparar a popula&#231;&#227;o de doentes com alguma forma de FA ou FLA com a popula&#231;&#227;o com ritmo sinusal de base durante o per&#237;odo de monitoriza&#231;&#227;o&#44; verificaram&#8208;se diferen&#231;as significativas &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; entre ambas relativamente aos seguintes par&#226;metros&#58; preval&#234;ncia significativamente maior de FA&#44; FAP ou FLA nos indiv&#237;duos do sexo masculino &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e nos indiv&#237;duos mais velhos &#40;sobretudo nas classes et&#225;rias dos 70&#8208;79 anos e<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>80 anos&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><p id="par0290" class="elsevierStylePara elsevierViewall">Elevado n&#250;mero de doentes com hipertens&#227;o arterial &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; sendo a percentagem absoluta de hipertensos neste grupo de 76&#44;5&#37;&#46; Existe tamb&#233;m uma percentagem significativamente superior de doentes com DPCO &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; J&#225; a ocorr&#234;ncia de diabetes <span class="elsevierStyleItalic">mellitus</span> e hipertiroidismo &#233; semelhante entre os dois grupos&#46; Menor&#44; embora significativo&#44; &#233; o excesso de doentes com dislipidemia nos doentes do grupo com qualquer tipo de FA e FLA&#44; relativamente ao grupo em que estas est&#227;o ausentes&#46;</p><p id="par0295" class="elsevierStylePara elsevierViewall">Por outro lado&#44; t&#234;m uma preval&#234;ncia significativamente maior de antecedentes de AVC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; 56 pacientes &#40;9&#44;3&#37;&#41;&#44; bem como de enfarte agudo do mioc&#225;rdio&#44; 5&#44;3&#37; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; O grupo com qualquer tipo de FA&#47;FLA apresenta um maior per&#237;metro abdominal &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e uma menor pr&#225;tica regular de exerc&#237;cio f&#237;sico &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; e maior consumo de bebidas alco&#243;licas &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;005&#41;&#46;</p><p id="par0300" class="elsevierStylePara elsevierViewall">Em rela&#231;&#227;o aos h&#225;bitos tab&#225;gicos&#44; podemos afirmar que em doentes com FA diagnosticada existe uma maior percentagem de doentes que nunca fumaram face &#224; popula&#231;&#227;o saud&#225;vel &#40;77&#44;1 <span class="elsevierStyleItalic">versus</span> 74&#44;5&#37;&#41;&#44; uma maior percentagem de ex&#8208;fumadores &#40;19&#44;2 <span class="elsevierStyleItalic">versus</span> 17&#44;6&#37;&#41; e uma menor percentagem de fumadores &#40;3&#44;7 <span class="elsevierStyleItalic">versus</span> 7&#44;9&#37;&#41;&#46;</p><p id="par0305" class="elsevierStylePara elsevierViewall">Relativamente ao motivo de pedido do exame&#58; os indiv&#237;duos com alguma forma de FA ou FLA t&#234;m uma preval&#234;ncia significativamente maior de exames pedidos por palpita&#231;&#245;es &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; tonturas &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; fraqueza&#47;dificuldade na realiza&#231;&#227;o de exerc&#237;cio f&#237;sico &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; dor tor&#225;cica &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; ou s&#237;ncope &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;005&#41;&#46; Fadiga&#44; dispneia&#44; confus&#227;o mental&#44; insufici&#234;ncia card&#237;aca&#44; AVC ou arritmia&#44; de uma forma geral&#44; foram motivos de pedido id&#234;nticos em ambos os grupos&#46;</p><p id="par0310" class="elsevierStylePara elsevierViewall">Verificou&#8208;se ainda uma preval&#234;ncia significativamente maior de FA persistente ou parox&#237;stica ou <span class="elsevierStyleItalic">flutter</span> nos indiv&#237;duos a receber medica&#231;&#227;o &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; e naqueles com informa&#231;&#227;o de diagn&#243;stico pr&#233;vio conhecido de alguma forma de FA &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; ou de FAP &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><p id="par0315" class="elsevierStylePara elsevierViewall">Em rela&#231;&#227;o &#224; sintomatologia assinalada pelo doente no decurso do exame&#44; verificou&#8208;se que a aus&#234;ncia de sintomatologia foi a regra em ambos os grupos &#40;84&#44;8 <span class="elsevierStyleItalic">versus</span> 74&#44;7&#37; dos doentes n&#227;o assinalaram sintomas&#41;&#44; mas significativamente mais doentes no grupo com FA&#47;FAP&#47;FLA n&#227;o o fizeram &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; As palpita&#231;&#245;es e dor tor&#225;cica foram os sintomas mais assinalados neste &#250;ltimo grupo &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; A rela&#231;&#227;o entre o tra&#231;ado do Holter e qualquer sintomatologia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;138&#41; &#233; baixa &#40;8&#44;3 <span class="elsevierStyleItalic">versus</span> 6&#44;7&#37;&#41; e n&#227;o significativa&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Caracteriza&#231;&#227;o dos indiv&#237;duos com fibrilha&#231;&#227;o auricular parox&#237;stica ou <span class="elsevierStyleItalic">flutter</span> auricular parox&#237;stico <span class="elsevierStyleItalic">versus</span> popula&#231;&#227;o com fibrilha&#231;&#227;o auricular persistente</span><p id="par0320" class="elsevierStylePara elsevierViewall">Ao comparar a popula&#231;&#227;o de doentes com FAP e FLA t&#237;pico parox&#237;stico &#40;FA&#47;FLAP&#41; <span class="elsevierStyleItalic">versus</span> a popula&#231;&#227;o com FA persistente&#44; verificaram&#8208;se diferen&#231;as significativas &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; entre ambas relativamente aos seguintes par&#226;metros&#58; preval&#234;ncia significativamente maior de FA&#47;FLAP nos indiv&#237;duos situados nas classes et&#225;rias mais jovens&#44; idades entre os 40&#8208;49&#44; 50&#8208;59 e 60&#8208;69 anos&#44; e significativamente menor nos indiv&#237;duos situados nas classes et&#225;rias dos 70&#8208;79 anos e<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>80 anos &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#59; preval&#234;ncia significativamente maior de antecedentes de AVC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;024&#41; e uma preval&#234;ncia significativamente menor de hipertens&#227;o arterial &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; nos doentes do grupo com FA&#47;FLAP&#44; em rela&#231;&#227;o aos indiv&#237;duos com FA persistente &#40;<a class="elsevierStyleCrossRef" href="#tbl0020">Tabela 4</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0325" class="elsevierStylePara elsevierViewall">Verificou&#8208;se uma preval&#234;ncia significativamente maior de pr&#225;tica regular de exerc&#237;cio f&#237;sico &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;049&#41;&#46;</p><p id="par0330" class="elsevierStylePara elsevierViewall">Comparativamente aos indiv&#237;duos com FA&#44; os indiv&#237;duos com FA&#47;FLAP t&#234;m uma preval&#234;ncia significativamente maior de palpita&#231;&#245;es &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;007&#41;&#44; arritmia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;008&#41; e extrassistolia e&#47;ou altera&#231;&#245;es eletrocardiogr&#225;ficas &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#59; e uma preval&#234;ncia significativamente menor de fraqueza ou dificuldade na realiza&#231;&#227;o de exerc&#237;cio f&#237;sico &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;037&#41;&#46; Verificou&#8208;se ainda uma preval&#234;ncia significativamente menor de toma de medica&#231;&#227;o &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;003&#41;<span class="elsevierStyleItalic">&#46;</span></p><p id="par0335" class="elsevierStylePara elsevierViewall">Em rela&#231;&#227;o &#224; sintomatologia do doente no momento do exame&#44; verificou&#8208;se que as palpita&#231;&#245;es &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;029&#41;&#44; s&#237;ncope &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;012&#41;&#44; arritmia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e rela&#231;&#227;o entre o tra&#231;ado do Holter e a sintomatologia atual &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;019&#41; eram significativamente mais prevalentes nos doentes com FA&#47;FLAP do que nos doentes com FA persistente&#46; De modo inverso&#44; a aus&#234;ncia de sintomas no momento do exame foi significativamente maior nos doentes com FA persistente do que nos doentes com FA&#47;FLAP &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;004&#41;&#46;</p></span></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Hipocoagula&#231;&#227;o oral</span><p id="par0340" class="elsevierStylePara elsevierViewall">Cento e tr&#234;s dos doentes &#40;2&#44;4&#37;&#41; que estavam em ritmo sinusal faziam hipocoagula&#231;&#227;o oral&#44; qualquer que fosse o motivo&#44; contudo apenas 29&#44;9&#37; dos doentes &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>135&#41; em FA persistente e 12&#44;8&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>14&#41; dos que apresentavam FAP estavam hipocoagulados&#46; Apenas seis dos 23 doentes &#40;26&#44;1&#37;&#41; com FLA isolado t&#237;pico estavam hipocoagulados&#46;</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Discuss&#227;o</span><p id="par0345" class="elsevierStylePara elsevierViewall">Para os objetivos prospetivamente delineados&#44; este estudo &#233; muito provavelmente o &#250;nico alguma vez realizado tendo como base a realiza&#231;&#227;o de monitoriza&#231;&#227;o cont&#237;nua de 24 horas e com 12 deriva&#231;&#245;es simult&#226;neas&#46;</p><p id="par0350" class="elsevierStylePara elsevierViewall">Um cuidado muito especial foi colocado na aquisi&#231;&#227;o dos dados e na interpreta&#231;&#227;o dos mesmos&#44; dado que o m&#233;dico referenciador n&#227;o tinha conhecimento da realiza&#231;&#227;o do estudo ou mesmo do local em que o mesmo seria realizado&#46;</p><p id="par0355" class="elsevierStylePara elsevierViewall">Os tra&#231;ados foram interpretados e diretamente registados numa base especialmente criada exclusivamente para este estudo&#44; em que os dois aritmologistas n&#227;o tinham conhecimento da identidade do paciente e da an&#225;lise efetuada pelo outro aritmologista&#46; Por fim&#44; os dados foram ainda confirmados por um terceiro elemento&#44; que analisou os tra&#231;ados em que houvesse discrep&#226;ncias em algum dos elementos classificados&#46; Os dados obtidos no question&#225;rio foram aqueles que habitualmente s&#227;o colhidos quando da coloca&#231;&#227;o e prepara&#231;&#227;o dos doentes&#46;</p><p id="par0360" class="elsevierStylePara elsevierViewall">O valor total da preval&#234;ncia de fibrilha&#231;&#227;o e FLA encontrado &#233; ainda mais elevado do que seria de esperar&#44; 12&#44;4&#37;&#44; o que mais uma vez levanta a quest&#227;o epidemiol&#243;gica da sua importante liga&#231;&#227;o ao AVC&#44; a import&#226;ncia de um precoce diagn&#243;stico&#44; especialmente tendo em considera&#231;&#227;o a profilaxia do acidente cardioemb&#243;lico e a orienta&#231;&#227;o para t&#233;cnicas de tratamento invasivas&#44; como &#233; o caso da abla&#231;&#227;o por cateter de radiofrequ&#234;ncia ou&#44; mais recentemente&#44; a crioabla&#231;&#227;o por bal&#227;o&#46;</p><p id="par0370" class="elsevierStylePara elsevierViewall">Para esta enorme percentagem podem concorrer enviesamentos&#44; do qual o mais importante &#233; a referencia&#231;&#227;o a partir do m&#233;dico de fam&#237;lia que pediu o exame de acordo com crit&#233;rios cl&#237;nicos pr&#243;prios&#44; que n&#227;o foram contudo pr&#233;&#8208;definidos&#44; embora por n&#243;s anotados&#46; Como j&#225; foi referido&#44; o m&#233;dico requisitante n&#227;o tinha informa&#231;&#227;o do decurso deste estudo e&#44; como tal&#44; a sua pr&#225;tica cl&#237;nica pode ter sido alterada&#46;</p><p id="par0375" class="elsevierStylePara elsevierViewall">O valor encontrado &#233; completamente discrepante dos que foram encontrados por Ascen&#231;&#227;o et al<span class="elsevierStyleItalic">&#46;</span><a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">8</span></a>&#44; num trabalho realizado em Portugal que abordava este assunto&#44; apenas 0&#44;5&#37;&#44; e por Gomes et al<span class="elsevierStyleItalic">&#46;</span><a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">9</span></a>&#44; 1&#44;29&#37;&#44; que estudaram todos os utentes de centros de sa&#250;de numa regi&#227;o do grande Porto com idades superiores a 30 anos&#46; Ambos os estudos foram baseados numa revis&#227;o retrospetiva de processos cl&#237;nicos&#46;</p><p id="par0380" class="elsevierStylePara elsevierViewall">A percentagem de FAP&#44; leia&#8208;se como j&#225; foi referido na introdu&#231;&#227;o&#44; FA que alterna nas 24 horas de monitoriza&#231;&#227;o com ritmo sinusal e&#44; como tal&#44; tamb&#233;m necessariamente subestimada&#44; atingiu os 2&#44;5&#37;&#44; id&#234;ntica &#224; percentagem total encontrada para a FA no estudo FAMA e&#44; se a esta percentagem juntarmos a do <span class="elsevierStyleItalic">flutter</span> parox&#237;stico&#44; n&#227;o inclu&#237;do neste n&#250;mero&#44; o total da preval&#234;ncia ainda &#233; superior&#46;</p><p id="par0385" class="elsevierStylePara elsevierViewall">Tal como aconteceu neste &#250;ltimo estudo&#44; foi nosso crit&#233;rio assumir num &#250;nico grupo os doentes com FA e os doentes com FLA t&#237;pico&#44; por se tratar de uma situa&#231;&#227;o arr&#237;tmica afim&#44; que muitas vezes alterna com aquela&#44; apresentando risco semelhante de AVC&#44; embora tenha um tratamento espec&#237;fico diferente&#44; abla&#231;&#227;o do istmo cavotricusp&#237;deo&#44; mas&#44; sem d&#250;vida&#44; muitas vezes interligado com o aparecimento de FA&#46;</p><p id="par0390" class="elsevierStylePara elsevierViewall">Foi a car&#234;ncia de dados relativos &#224; popula&#231;&#227;o portuguesa e a variabilidade das estimativas da preval&#234;ncia da FA em estudos europeus&#44; que levou &#224; realiza&#231;&#227;o de um estudo transversal a n&#237;vel da comunidade&#44; o estudo FAMA&#44; procurando&#8208;se obter uma amostra representativa da popula&#231;&#227;o portuguesa com 40 ou mais anos de idade&#44; estratificada por sexo&#44; idade e regi&#227;o do pa&#237;s&#46; Foi assim elaborado um protocolo&#44; que inclu&#237;a um inqu&#233;rito e a realiza&#231;&#227;o de um ECG&#44; e recolher dados relativos a uma amostra considerada significativa &#8211; mais de 10<span class="elsevierStyleHsp" style=""></span>000 indiv&#237;duos com 40 ou mais anos&#44; selecionados de forma aleat&#243;ria e provenientes de todas as regi&#245;es do pa&#237;s&#46;</p><p id="par0395" class="elsevierStylePara elsevierViewall">A mais&#8208;valia do estudo FAMA foi&#44; sem d&#250;vida&#44; a comprova&#231;&#227;o da FA num dado instante&#44; pela realiza&#231;&#227;o de ECG&#46; As limita&#231;&#245;es do estudo FAMA decorrem da brevidade da documenta&#231;&#227;o&#44; poucos segundos&#44; e da elevada taxa de indiv&#237;duos que&#44; por diversas raz&#245;es&#44; n&#227;o se quiseram submeter ao inqu&#233;rito e consequentemente ao ECG&#46; Foram avaliados 10<span class="elsevierStyleHsp" style=""></span>447 indiv&#237;duos e o n&#250;mero daqueles que&#44; embora reunissem condi&#231;&#245;es de participa&#231;&#227;o&#44; recusaram foi muito superior&#44; 15<span class="elsevierStyleHsp" style=""></span>507&#46; Das raz&#245;es de recusa na participa&#231;&#227;o nada sabemos&#44; mas quest&#245;es metodol&#243;gicas que ultrapassam o &#226;mbito desta discuss&#227;o podem estar na origem&#46;</p><p id="par0400" class="elsevierStylePara elsevierViewall">No presente estudo&#44; a monitoriza&#231;&#227;o foi efetuada durante 24 horas tendo a realiza&#231;&#227;o do exame um motivo devidamente expresso pelo requisitante&#44; n&#227;o tendo sido dif&#237;cil obter o consentimento informado para a realiza&#231;&#227;o de um exame que teria que ser realizado por motivos cl&#237;nicos de qualquer maneira&#46;</p><p id="par0405" class="elsevierStylePara elsevierViewall">O tempo de monitoriza&#231;&#227;o expande dramaticamente a possibilidade de registo de um epis&#243;dio de FA&#44; pelo que seria <span class="elsevierStyleItalic">a priori</span> l&#243;gico esperar uma preval&#234;ncia superior da mesma&#46; Por outro lado&#44; tempos de monitoriza&#231;&#227;o mais prolongados&#44; se bem que pudessem aumentar ainda mais a hip&#243;tese de diagn&#243;stico desta arritmia&#44; tornam&#8208;se impratic&#225;veis&#44; especialmente devido &#224; <span class="elsevierStyleItalic">compliance</span> do doente e&#44; como tal&#44; limitado a popula&#231;&#245;es muito espec&#237;ficas<a class="elsevierStyleCrossRefs" href="#bib0125"><span class="elsevierStyleSup">10&#44;11</span></a>&#46;</p><p id="par0410" class="elsevierStylePara elsevierViewall">Foi perguntado aos participantes em ritmo sinusal durante o registo se existiria um diagn&#243;stico pr&#233;vio de FA&#44; tendo 59 doentes respondido afirmativamente&#44; o que corresponde a uma percentagem de 1&#44;4&#37;&#46; Do mesmo modo&#44; foram questionados da exist&#234;ncia pr&#233;via de FAP&#44; tendo 102 respondido que sim ou seja 2&#44;4&#37;&#46; Assumindo como verdadeiras todas as respostas&#44; e n&#227;o considerando a &#243;bvia sobreposi&#231;&#227;o de respostas num mesmo indiv&#237;duo&#44; poder&#237;amos especular um excesso de preval&#234;ncia de FA de mais 3&#44;8&#37; em acr&#233;scimo aos 12&#44;4&#37; que objetiv&#225;mos atrav&#233;s neste estudo prospetivo&#46; Significa isto tamb&#233;m que&#44; quanto mais longa a monitoriza&#231;&#227;o&#44; maior ir&#225; ser a preval&#234;ncia de FA&#46;</p><p id="par0415" class="elsevierStylePara elsevierViewall">Foi o que provaram Gladstone et al<span class="elsevierStyleItalic">&#46;</span><a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">10</span></a> ao estudar a rela&#231;&#227;o entre FA e AVC criptog&#233;nico&#44; em doentes com idade igual ou superior a 55 anos e AVC ou AIT recente&#46; A monitoriza&#231;&#227;o de 30 dias era superior &#224; monitoriza&#231;&#227;o de 24 horas&#44; com efic&#225;cia diagn&#243;stica cinco vezes superior e consequente aumento das consequ&#234;ncias terap&#234;uticas com duplica&#231;&#227;o da indica&#231;&#227;o para hipocoagula&#231;&#227;o oral aos 90 dias de seguimento&#46; Uma monitoriza&#231;&#227;o prolongada tem&#44; contudo&#44; problemas de <span class="elsevierStyleItalic">compliance</span> e os artefactos podem&#8208;se tornar um problema&#46;</p><p id="par0420" class="elsevierStylePara elsevierViewall">O nosso estudo demonstra&#44; contudo&#44; a ineg&#225;vel utilidade do Holter de 24 horas no diagn&#243;stico de FAP&#44; pois somente 5&#44;0&#37; dos doentes no grupo dos que tinham FAP no Holter referiam diagn&#243;stico pr&#233;vio&#46; Em contraste&#44; 57&#44;5&#37; dos doentes que tinham FA persistente&#44; durante as 24 horas&#44; tinham diagn&#243;stico pr&#233;vio de FA persistente ou permanente&#44; definidas segundo as recomenda&#231;&#245;es internacionais&#46; Isto significa que o Holter ter&#225; sido realizado&#44; neste &#250;ltimo caso inserido numa estrat&#233;gia de controlo de frequ&#234;ncia card&#237;aca t&#227;o popular depois da publica&#231;&#227;o do estudo AFFIRM<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">12</span></a>&#44; mas que o diagn&#243;stico de FAP &#233; realizado em 95&#37; dos casos pela primeira vez&#44; com todas as consequ&#234;ncias de orienta&#231;&#227;o cl&#237;nica que isso possa ter&#46;</p><p id="par0425" class="elsevierStylePara elsevierViewall">A distribui&#231;&#227;o et&#225;ria da FAP &#233; diferente da FA persistente&#44; sendo significativamente superior em idades mais jovens&#44; 7&#44;5 <span class="elsevierStyleItalic">versus</span> 0&#44;2&#37; na d&#233;cada dos 40 anos e 11&#44;6 contra 6&#44;6&#37; na dos 50 anos&#46; A partir dessa idade a situa&#231;&#227;o inverte&#8208;se&#44; mantendo&#8208;se o diagn&#243;stico de FAP com n&#250;meros absolutos elevados e nunca significativamente inferiores&#46; Isto significa que a FAP &#233; um problema transversal a todas as idades e n&#227;o somente um problema do envelhecimento&#46;</p><p id="par0430" class="elsevierStylePara elsevierViewall">Uma palavra para o FLA&#58; o Holter de 12 deriva&#231;&#245;es permite o diagn&#243;stico de FLA t&#237;pico consoante a defini&#231;&#227;o globalmente aceite&#44; n&#227;o sendo desprez&#225;vel a percentagem elevada de <span class="elsevierStyleItalic">flutter</span> t&#237;pico isolado encontrada&#58; 0&#44;8&#37;</p><p id="par0435" class="elsevierStylePara elsevierViewall">Se por um lado as implica&#231;&#245;es de risco tromboemb&#243;lico s&#227;o id&#234;nticas &#224;s da FA&#44; por outro lado o tratamento desta situa&#231;&#227;o &#233; diferente&#44; sendo a abla&#231;&#227;o por cateter potencialmente curativa em percentagem superior &#224; da abla&#231;&#227;o da FA&#44; sendo bem conhecida a dificuldade de controlar a frequ&#234;ncia card&#237;aca com f&#225;rmacos e a revers&#227;o duradoira a ritmo sinusal em doentes com esta situa&#231;&#227;o&#46;</p><p id="par0440" class="elsevierStylePara elsevierViewall">O FLA pode coexistir ou preceder a FA&#44; e a rela&#231;&#227;o entre ambos &#233; complexa&#46; Alguns autores defendem que em doentes em que coexista FA e FLA&#44; ou mesmo no <span class="elsevierStyleItalic">flutter</span> isolado&#44; deve ser realizada a abla&#231;&#227;o percut&#226;nea sim da FA e&#44; eventualmente&#44; apenas em associa&#231;&#227;o com a abla&#231;&#227;o do istmo cavotricusp&#237;deo<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">15</span></a>&#46;</p><p id="par0445" class="elsevierStylePara elsevierViewall">Certamente que os elevados valores de AVC encontrados por Moreira et al<span class="elsevierStyleItalic">&#46;</span>&#44; j&#225; referidos na introdu&#231;&#227;o<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">3</span></a>&#44; e numa popula&#231;&#227;o grosseiramente sobrepon&#237;vel geograficamente &#224; nossa&#44; podem estar relacionados com os elevados valores de preval&#234;ncia da FA encontrada neste estudo&#58; uma preval&#234;ncia significativamente maior de antecedentes de AVC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; 9&#44;3&#37; nos doentes com todos os tipos de fibrilha&#231;&#227;o e&#47;ou <span class="elsevierStyleItalic">flutter</span>&#44; mais ainda nos doentes com FAP comparativamente &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;024&#41;&#46;</p><p id="par0450" class="elsevierStylePara elsevierViewall">Ressalta da compara&#231;&#227;o entre os grupos de FA&#47;<span class="elsevierStyleItalic">flutter</span> parox&#237;stico e FA persistente que a liga&#231;&#227;o entre hipertens&#227;o arterial &#233; mais forte nesta &#250;ltima do que no primeiro grupo&#46; Os doentes do primeiro grupo t&#234;m significativamente menos hipertens&#227;o do que o &#250;ltimo&#44; embora doentes de ambos os grupos tenham significativamente mais hipertens&#227;o do que aqueles que permaneceram em ritmo sinusal&#46; Isto pode significar que a hipertens&#227;o&#44; tida como fator de risco cl&#225;ssico para o aparecimento de FA&#44; pode n&#227;o ter tanta import&#226;ncia numa fase inicial da doen&#231;a&#44; a FAP&#44; e que o seu in&#237;cio &#233; ditado por fatores desencadeantes&#44; usualmente com ponto de partida das veias pulmonares muito intensos e independentes&#44; e primariamente el&#233;tricos<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">13</span></a>&#46; Esta afirma&#231;&#227;o parece&#8208;nos especialmente pertinente&#44; pois consideramos que a FAP n&#227;o &#233; toda igual&#46; Os doentes podem apresentar epis&#243;dios sintom&#225;ticos e raros ao longo do tempo&#44; passando bem entre epis&#243;dios&#44; e que poder&#225; corresponder a um <span class="elsevierStyleItalic">trigger</span> pouco intenso num substrato auricular muito vulner&#225;vel ou&#44; tal como acontece nos doentes com FAP identificada neste estudo&#44; representar um subgrupo com <span class="elsevierStyleItalic">triggers</span> intensos e persistentes&#44; mas com um substrato auricular ainda suficiente resistente para n&#227;o permitir a sustentabilidade da FA&#46; Cumulativamente ao facto de estarmos a falar de doentes mais jovens&#44; pois a distribui&#231;&#227;o et&#225;ria da FAP &#233; transversal a todas as idades&#44; uma interven&#231;&#227;o precoce com t&#233;cnicas invasivas&#44; o isolamento das veias pulmonares e que &#233; comprovadamente mais eficaz do que os f&#225;rmacos antiarr&#237;tmicos&#44; pode ser o tratamento de elei&#231;&#227;o<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">10</span></a>&#46; &#201; tamb&#233;m sabido que a taxa de sucesso deste tratamento &#233; superior quando precocemente indicado<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">14</span></a>&#46;</p><p id="par0455" class="elsevierStylePara elsevierViewall">Por fim&#44; mais uma vez&#44; foram encontradas taxas muito baixas de hipocoagula&#231;&#227;o oral&#44; tal como foram encontradas noutros estudos<a class="elsevierStyleCrossRefs" href="#bib0095"><span class="elsevierStyleSup">4&#44;9</span></a>&#44; apenas 29&#44;9&#37; dos doentes em FA persistente nas 24 horas e ainda menor&#44; 12&#44;8&#37;&#44; nos doentes que apresentavam FAP&#46; A explica&#231;&#227;o deste &#250;ltimo facto &#233; l&#243;gica&#44; curta e simples&#58; os doentes n&#227;o est&#227;o hipocoagulados porque n&#227;o est&#227;o diagnosticados&#46;</p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Conclus&#245;es</span><p id="par0460" class="elsevierStylePara elsevierViewall">A preval&#234;ncia da FA encontrada numa popula&#231;&#227;o submetida&#44; por motivos n&#227;o selecionados&#44; a Holter de 24 horas &#233; de 12&#44;4&#37;&#44; o que significa que &#233; cinco vezes superior &#224; encontrada no estudo FAMA e que a percentagem de doentes com FAP&#44; ainda que subestimada&#44; &#233; de 2&#44;5&#37;&#44; apresentando uma distribui&#231;&#227;o et&#225;ria mais uniforme e&#44; como tal&#44; afetando doentes mais jovens e menos dependente de fatores de risco como hipertens&#227;o arterial&#46; Contudo&#44; apresentando percentagens significativamente superiores de AVC&#46; Estes doentes apresentam&#8208;se numa fase precoce da doen&#231;a e pass&#237;veis de ser candidatos a tratamento por abla&#231;&#227;o por cateter&#44; tratamento que apresenta uma elevada taxa de sucesso quando aplicado nesta fase&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Responsabilidades &#233;ticas</span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">Prote&#231;&#227;o de pessoas e animais</span><p id="par0465" class="elsevierStylePara elsevierViewall">Os autores declaram que os procedimentos seguidos estavam de acordo com os regulamentos estabelecidos pelos respons&#225;veis da Comiss&#227;o de Investiga&#231;&#227;o Cl&#237;nica e &#233;tica e de acordo com os da Associa&#231;&#227;o M&#233;dica Mundial e da Declara&#231;&#227;o de Helsinki&#46;</p></span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">Confidencialidade dos dados</span><p id="par0470" class="elsevierStylePara elsevierViewall">Os autores declaram ter seguido os protocolos do seu centro de trabalho acerca da publica&#231;&#227;o dos dados de pacientes&#46;</p></span><span id="sec0080" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0140">Direito &#224; privacidade e consentimento escrito</span><p id="par0475" class="elsevierStylePara elsevierViewall">Os autores declaram ter recebido consentimento escrito dos pacientes e&#47; ou sujeitos mencionados no artigo&#46; O autor para correspond&#234;ncia deve estar na posse deste documento&#46;</p></span></span><span id="sec0085" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0145">Fontes de financiamento</span><p id="par0480" class="elsevierStylePara elsevierViewall">N&#227;o existiram fontes externas de financiamento para a realiza&#231;&#227;o deste artigo&#46;</p></span><span id="sec0090" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0150">Conflito de interesses</span><p id="par0485" class="elsevierStylePara elsevierViewall">O estudo FAP &#233; promovido pela <span class="elsevierStyleItalic">Forpoint</span> &#8211; Instituto de Forma&#231;&#227;o e Inova&#231;&#227;o na Sa&#250;de&#44; tem o suporte editorial da <span class="elsevierStyleItalic">Keypoint</span> &#8211; Consultoria Cient&#237;fica&#44; e recebeu um apoio n&#227;o condicionado da&#160;Sanofi Portugal&#46;</p><p id="par0490" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o ter outros conflitos de interesses relativamente ao presente artigo&#46;</p></span></span>"
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          "titulo" => "Material e m&#233;todos"
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          "identificador" => "sec0020"
          "titulo" => "An&#225;lise estat&#237;stica"
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          "identificador" => "sec0025"
          "titulo" => "Resultados"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "sec0030"
              "titulo" => "Caracteriza&#231;&#227;o do perfil da popula&#231;&#227;o analisada"
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              "identificador" => "sec0035"
              "titulo" => "Preval&#234;ncia de fibrilha&#231;&#227;o auricular parox&#237;stica&#44; fibrilha&#231;&#227;o auricular e flutter"
            ]
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              "identificador" => "sec0040"
              "titulo" => "Caracteriza&#231;&#227;o dos indiv&#237;duos com fibrilha&#231;&#227;o auricular e compara&#231;&#227;o com a popula&#231;&#227;o sem fibrilha&#231;&#227;o auricular"
            ]
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              "titulo" => "Caracteriza&#231;&#227;o dos indiv&#237;duos com fibrilha&#231;&#227;o auricular parox&#237;stica ou flutter auricular parox&#237;stico versus popula&#231;&#227;o com fibrilha&#231;&#227;o auricular persistente"
            ]
          ]
        ]
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          "identificador" => "sec0050"
          "titulo" => "Hipocoagula&#231;&#227;o oral"
        ]
        10 => array:2 [
          "identificador" => "sec0055"
          "titulo" => "Discuss&#227;o"
        ]
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          "identificador" => "sec0060"
          "titulo" => "Conclus&#245;es"
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          "identificador" => "sec0065"
          "titulo" => "Responsabilidades &#233;ticas"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0070"
              "titulo" => "Prote&#231;&#227;o de pessoas e animais"
            ]
            1 => array:2 [
              "identificador" => "sec0075"
              "titulo" => "Confidencialidade dos dados"
            ]
            2 => array:2 [
              "identificador" => "sec0080"
              "titulo" => "Direito &#224; privacidade e consentimento escrito"
            ]
          ]
        ]
        13 => array:2 [
          "identificador" => "sec0085"
          "titulo" => "Fontes de financiamento"
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          "identificador" => "sec0090"
          "titulo" => "Conflito de interesses"
        ]
        15 => array:2 [
          "identificador" => "xack291284"
          "titulo" => "Agradecimentos"
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        16 => array:1 [
          "titulo" => "Bibliografia"
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    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2016-08-02"
    "fechaAceptado" => "2016-11-15"
    "PalabrasClave" => array:2 [
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          "clase" => "keyword"
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            0 => "Fibrilha&#231;&#227;o auricular parox&#237;stica"
            1 => "Monitoriza&#231;&#227;o eletrocardiogr&#225;fica"
            2 => "Fatores de risco"
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          "palabras" => array:3 [
            0 => "Paroxysmal atrial fibrillation"
            1 => "Electrocardiographic monitoring"
            2 => "Risk factors"
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        "titulo" => "Resumo"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introdu&#231;&#227;o</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A fibrilha&#231;&#227;o auricular &#40;FA&#41; &#233; a arritmia sustentada mais frequente na pr&#225;tica cl&#237;nica&#44; constituindo uma importante causa de morbilidade pelo risco associado de acidente vascular cerebral &#40;AVC&#41;&#46; Devido ao seu car&#225;ter muitas vezes parox&#237;stico encontra&#8208;se&#44; contudo&#44; subdiagnosticada e subtratada&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Objetivos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudo prospetivo que tem como objetivo principal o c&#225;lculo da preval&#234;ncia da FA parox&#237;stica em doentes com 40 ou mais anos de idade&#44; numa popula&#231;&#227;o submetida a monitoriza&#231;&#227;o eletrocardiogr&#225;fica cont&#237;nua de 24 horas&#46; Como objetivos secund&#225;rios&#58; o c&#225;lculo da preval&#234;ncia total de FA e <span class="elsevierStyleItalic">flutter</span> auricular &#40;FLA&#41;&#44; independentemente do tipo&#44; e a compara&#231;&#227;o entre as popula&#231;&#245;es com FA <span class="elsevierStyleItalic">versus</span> popula&#231;&#227;o total e FA parox&#237;stica <span class="elsevierStyleItalic">versus</span> FA persistente nas 24 horas&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Este estudo analisou um total de 4843 doentes consecutivos&#44; 58&#37; dos quais do sexo feminino&#46; Vinte seis v&#237;rgula dois por cento dos doentes encontrava&#8208;se na faixa et&#225;ria dos 70&#8208;79 anos &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1269&#41;&#44; 25&#44;9&#37; &#40;n&#8208;1252&#41; entre os 60&#8208;69 anos e 19&#44;0&#37; &#40;n&#8208;923&#41; entre os 50&#8208;59 anos&#59; os restantes doentes ou tinham idades superiores a 80 anos &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>712&#44; 14&#44;7&#37;&#41;&#44; ou inferiores a 50 &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>686&#44; 14&#44;2&#37;&#41;&#46; Entre os doentes referenciados e analisados&#44; registaram&#8208;se 123 com registo de pelo menos um per&#237;odo de FA parox&#237;stica&#44; o que equivale a uma preval&#234;ncia de 2&#44;5&#37; &#40;IC a 95&#37;&#44; 2&#44;1&#8208;3&#44;0&#41;&#46; A preval&#234;ncia de doentes com FA durante todo o registo foi de 9&#44;4&#37; &#40;IC a 95&#37;&#44; 8&#44;6&#8208;10&#44;2&#41; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>454&#41;&#46; Registaram&#8208;se ainda 39 casos de doentes com <span class="elsevierStyleItalic">flutter</span> t&#237;pico&#44; mas em 23 quer mantido quer parox&#237;stico aparecia isolado&#44; o que corresponde a uma preval&#234;ncia de 0&#44;8&#37; &#40;IC a 95&#37;&#44; 0&#44;6 a 1&#44;1&#41;&#46; Tal indica que a preval&#234;ncia de doentes com FA&#47;FL total &#233; de 12&#44;4&#37;&#46; A presen&#231;a de alguma forma de FA&#47;FLA correlacionou&#8208;se significativamente com sexo masculino &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e idade &#40;sobretudo nas classes et&#225;rias dos 70&#8208;79 anos e<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>80 anos&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; com hipertens&#227;o arterial &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Este grupo tem uma preval&#234;ncia significativamente maior de antecedentes de AVC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; 56 pacientes &#40;9&#44;3&#37;&#41;&#44; bem como de enfarte agudo do mioc&#225;rdio&#44; 5&#44;3&#37; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Ao comparar a popula&#231;&#227;o de doentes com FA parox&#237;stica e FLA parox&#237;stico &#40;FA&#47;FLp&#41; <span class="elsevierStyleItalic">versus</span> FA persistente&#44; verificaram&#8208;se diferen&#231;as significativas &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; entre ambos nos seguintes par&#226;metros&#58; preval&#234;ncia significativamente maior de FA&#47;FLp nos indiv&#237;duos situados nas classes et&#225;rias mais jovens &#40;entre os 40&#8208;49&#44; 50&#8208;59 e 60&#8208;69 anos&#41;&#44; e significativamente menor nos indiv&#237;duos situados nas classes et&#225;rias dos 70&#8208;79 anos e<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>80 anos &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#59; preval&#234;ncia significativamente maior de antecedentes de AVC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;024&#41; e significativamente menor de hipertens&#227;o arterial &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Apenas 12&#44;8&#37; dos que apresentavam FA parox&#237;stica estavam hipocoagulados&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclus&#245;es</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A preval&#234;ncia da FA parox&#237;stica encontrada numa popula&#231;&#227;o submetida por motivos n&#227;o selecionados a monitoriza&#231;&#227;o eletrocardiogr&#225;fica de 24 horas &#233; de 2&#44;5&#37; e a preval&#234;ncia total de FA&#47;FLA &#233; de 12&#44;4&#37;&#46; A FA parox&#237;stica afeta doentes mais jovens&#44; sendo menos dependente de fatores de risco&#44; como hipertens&#227;o arterial&#46; Correlaciona&#8208;se com percentagens significativamente superiores de AVC&#46; A dete&#231;&#227;o sistem&#225;tica destes doentes &#233; um importante problema de sa&#250;de p&#250;blica sendo diagn&#243;stico precoce essencial na defini&#231;&#227;o de candidatos para hipocoagula&#231;&#227;o oral e tratamento por abla&#231;&#227;o por cateter&#44; a qual apresenta uma elevada taxa de sucesso curativa quando aplicada nesta fase&#46;</p></span>"
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          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introdu&#231;&#227;o"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Objetivos"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Resultados"
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            "titulo" => "Conclus&#245;es"
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        "titulo" => "Abstract"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Atrial fibrillation &#40;AF&#41; is the most common sustained arrhythmia in clinical practice and a major cause of morbidity&#44; due to the associated risk of stroke&#46; However&#44; since it is often paroxysmal&#44; it is commonly underdiagnosed and undertreated&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Objectives</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">The primary objective of this prospective study was to determine the prevalence of paroxysmal atrial fibrillation &#40;PAF&#41; in patients aged 40 and above in a population who underwent continuous 24&#8208;hour electrocardiographic monitoring&#46; The secondary objectives were to determine the overall prevalence of AF&#47;atrial flutter &#40;AFL&#41; regardless of the type and to compare the population with AF with the general population and patients with PAF with patients with AF&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Results</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">A total of 4843 consecutive patients were analyzed&#44; 58&#37; women&#44; 26&#46;2&#37; aged 70&#8208;79 years &#40;n&#61;1269&#41;&#44; 25&#46;9&#37; &#40;n&#61;1252&#41; aged 60&#8208;69 years&#44; and 19&#46;0&#37; &#40;n&#61;923&#41; aged 50&#8208;59 years&#59; the others were aged either &#62;80 years &#40;n&#61;712&#44; 14&#46;7&#37;&#41; or &#60;50 years &#40;n&#61;686&#44; 14&#46;2&#37;&#41;&#46; At least one episode of PAF was detected in 123 patients&#44; a prevalence of 2&#46;5&#37; &#40;95&#37; CI&#58; 2&#46;1&#8208;3&#46;0&#41;&#46; The prevalence of persistent AF throughout the monitoring period was 9&#46;4&#37; &#40;95&#37; CI&#58; 8&#46;6&#8208;10&#46;2&#41; &#40;n&#61;454&#41;&#46; Additionally&#44; 39 cases of typical AFL were detected&#44; but in 23 of them &#40;sustained or paroxysmal&#41; this appeared isolated&#44; a prevalence of 0&#46;8&#37; &#40;95&#37; CI&#58; 0&#46;6&#8208;1&#46;1&#41;&#46; The overall prevalence of AF&#47;AFL was thus 12&#46;4&#37;&#46; The presence of some type of AF&#47;AFL was significantly correlated with male gender &#40;p&#60;0&#46;001&#41;&#44; age &#40;especially in the 70&#8208;79 and &#62;80 age&#8208;groups&#41; &#40;p&#60;0&#46;001&#41; and hypertension &#40;p&#60;0&#46;001&#41;&#46; This group had a significantly higher prevalence of previous stroke &#40;56 patients &#91;9&#46;3&#37;&#93;&#44; p&#61;0&#46;001&#41; and acute myocardial infarction &#40;5&#46;3&#37;&#44; p&#60;0&#46;001&#41;&#46; Comparing the population with PAF and&#47;or paroxysmal AFL &#40;PAF&#47;PAFL&#41; to those with persistent AF &#40;during 24&#8208;hour monitoring&#41;&#44; significant differences were found&#58; a higher prevalence of PAF&#47;PAFL in younger individuals &#40;40&#8208;49&#44; 50&#8208;59 and 60&#8208;69 age&#8208;groups&#41; and lower in older individuals &#40;70&#8208;79 and &#62;80 age&#8208;groups&#41; &#40;p&#60;0&#46;001&#41;&#44; higher prevalence of history of stroke &#40;p&#61;0&#46;024&#41;&#44; and lower levels of hypertension &#40;p&#60;0&#46;001&#41;&#46; Only 12&#46;8&#37; of patients with PAF were taking anticoagulant drugs&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusions</span><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">The prevalence of PAF found in a population referred for continuous 24&#8208;hour electrocardiographic monitoring for diverse reasons was 2&#46;5&#37; and the overall AF&#47;AFL prevalence was 12&#46;4&#37;&#46; PAF was more prevalent in younger patients&#46; Patients with PAF showed a significantly lower prevalence of hypertension and significantly higher rates of stroke&#46; Systematically detecting patients with PAF is a major public health concern&#44; since early diagnosis is essential to identify candidates for oral anticoagulation and catheter ablation&#44; which is frequently curative when applied at this stage&#46;</p></span>"
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Caracter&#237;stica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Popula&#231;&#227;o em estudo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Sexo&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Masculino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41&#44;6 &#40;2013&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Feminino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">58&#44;4 &#40;2829&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Grupo et&#225;rio&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>40&#8208;49 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14&#44;2 &#40;686&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>50&#8208;59 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#44;1 &#40;923&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>60&#8208;69 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&#44;9 &#40;1252&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>70&#8208;79 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#44;2 &#40;1269&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14&#44;7 &#40;712&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Per&#237;metro abdominal&#44; m&#233;dia cm &#40;DP&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">93&#44;1 &#40;11&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>IMC&#44; m&#233;dia kg&#47;m<span class="elsevierStyleSup">2</span> &#40;DP&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#44;7 &#40;4&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Fatores de risco &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pr&#225;tica regular de exerc&#237;cio f&#237;sico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#44;8 &#40;1104&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>H&#225;bitos tab&#225;gicos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nunca fumou&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">74&#44;6 &#40;3612&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ex&#8208;fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17&#44;9 &#40;865&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;5 &#40;365&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>H&#225;bitos alco&#243;licos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">39&#44;5 &#40;1911&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertens&#227;o arterial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">62&#44;0 &#40;3004&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dislipidemia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46&#44;1 &#40;2230&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diabetes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#44;9 &#40;772&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertiroidismo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;2 &#40;155&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>DPOC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;5 &#40;217&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Hist&#243;ria de doen&#231;a cardiovascular&#44; &#37;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hist&#243;ria familiar de doen&#231;a CV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">40&#44;7 &#40;1971&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>AVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46&#44;0 &#40;907&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>EAM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">83&#44;4 &#40;658&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Morte s&#250;bita&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;6 &#40;149&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Valvulopatia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;7 &#40;92&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Arritmia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#44;4 &#40;324&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ocorr&#234;ncia de enfarte agudo do mioc&#225;rdio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;4 &#40;165&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ocorr&#234;ncia de AVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;5 &#40;267&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Motivo da prescri&#231;&#227;o do exame&#47;sintomatologia&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Palpita&#231;&#245;es&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21&#44;0 &#40;1016&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fadiga&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#44;4 &#40;744&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dispneia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;4 &#40;366&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tonturas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;8 &#40;524&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;ncope&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;1 &#40;391&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Confus&#227;o mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;3 &#40;13&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>ICC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;1 &#40;103&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>AVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;1 &#40;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Arritmia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;5 &#40;71&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fraqueza ou dificuldade na realiza&#231;&#227;o de exerc&#237;cio f&#237;sico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#44;8 &#40;958&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dor tor&#225;cica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;1 &#40;394&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Avalia&#231;&#227;o cardiovascular&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">31&#44;2 &#40;1511&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Extrassistolia e&#47;ou altera&#231;&#245;es eletrocardiogr&#225;ficas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;9 &#40;239&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Medica&#231;&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">88&#44;0 &#40;4261&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diagn&#243;stico pr&#233;vio de FA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;3 &#40;404&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diagn&#243;stico pr&#233;vio de FA parox&#237;stica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;7 &#40;132&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Sintomatologia do doente no exame&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Palpita&#231;&#245;es&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;4 &#40;408&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fadiga&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;8 &#40;232&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dispneia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;9 &#40;142&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tonturas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;9 &#40;288&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;ncope&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;2 &#40;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Confus&#227;o mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;0 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>ICC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;9 &#40;42&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Arritmia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;0 &#40;145&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dor tor&#225;cica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;2 &#40;349&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sem sintomas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">76&#44;0 &#40;3679&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Rela&#231;&#227;o entre o tra&#231;ado do Holter e a sintomatologia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;9 &#40;334&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Categoria do f&#225;rmaco&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Doentes que alguma vez utilizaram o f&#225;rmaco &#40;&#37;&#44; n&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Doentes que utilizam o f&#225;rmaco no presente &#40;&#37;&#44; n&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antiarr&#237;tmicos&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;7 &#40;131&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">IECAS&#44; ARA II&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48&#44;4 &#40;2344&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#44;7 &#40;1295&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antidiab&#233;ticos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#44;9 &#40;817&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;2 &#40;496&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Diur&#233;ticos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#44;8 &#40;815&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;8 &#40;426&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Betabloqueantes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#44;8 &#40;1103&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;5 &#40;558&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antagonistas do c&#225;lcio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&#44;5 &#40;603&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;7 &#40;324&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Hipocoagula&#231;&#227;o oral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;4 &#40;505&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#40;261&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antiagrega&#231;&#227;o plaquet&#225;ria&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">28&#44;7 &#40;1390&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#44;0 &#40;725&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PUFA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;2 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;2 &#40;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antidislipid&#233;micos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41&#44;5 &#40;2011&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#44;6 &#40;1093&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Caracter&#237;stica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Popula&#231;&#227;o FA<span class="elsevierStyleHsp" style=""></span>&#43;FAP<span class="elsevierStyleHsp" style=""></span>&#43;<span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">flutter</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Popula&#231;&#227;o geral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Sexo&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Masculino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#44;3 &#40;314&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">40&#44;1 &#40;1699&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Feminino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">47&#44;7 &#40;286&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59&#44;9 &#40;2543&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Grupo et&#225;rio&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>40&#8208;49 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;0 &#40;12&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#44;9 &#40;674&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>50&#8208;59 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;8 &#40;47&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&#44;7 &#40;876&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>60&#8208;69 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&#44;8 &#40;125&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#44;6 &#40;1127&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>70&#8208;79 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">39&#44;8 &#40;239&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24&#44;3 &#40;1030&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29&#44;5 &#40;177&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&#44;6 &#40;535&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Per&#237;metro abdominal&#44; m&#233;dia cm &#40;DP&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#44;6 &#40;11&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">92&#44;7 &#40;11&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>IMC&#44; m&#233;dia kg&#47;m<span class="elsevierStyleSup">2</span> &#40;DP&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27&#44;1 &#40;3&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#44;8 &#40;4&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;089&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Fatores de risco&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pr&#225;tica regular de exerc&#237;cio f&#237;sico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14&#44;8 &#40;89&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">23&#44;9 &#40;1015&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>H&#225;bitos tab&#225;gicos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nunca fumou&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">75&#44;5 &#40;453&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">74&#44;5 &#40;3159&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;011&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ex&#8208;fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#44;8 &#40;119&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17&#44;6 &#40;746&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;7 &#40;28&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;9 &#40;337&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>H&#225;bitos alco&#243;licos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">44&#44;7 &#40;268&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">38&#44;7 &#40;1643&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertens&#227;o arterial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">76&#44;3 &#40;458&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">60&#44;0 &#40;2546&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dislipidemia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">51&#44;2 &#40;307&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">45&#44;3 &#40;1923&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;014&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diabetes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#44;0 &#40;114&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#44;5 &#40;658&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;062&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertiroidismo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;7 &#40;22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;1 &#40;133&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;787&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>DPOC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;8 &#40;41&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;1 &#40;176&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Hist&#243;ria de doen&#231;a cardiovascular&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>AVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46&#44;3 &#40;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46&#44;0 &#40;819&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;931&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>EAM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#44;7 &#40;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#44;2 &#40;592&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;677&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Morte s&#250;bita&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;7 &#40;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;9 &#40;140&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;122&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Valvulopatia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;7 &#40;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;8 &#40;85&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;499&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Arritmia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#44;3 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#44;4 &#40;274&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ocorr&#234;ncia de enfarte agudo do mioc&#225;rdio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;3 &#40;32&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;1 &#40;133&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ocorr&#234;ncia de AVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;3 &#40;56&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;0 &#40;211&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Sintomatologia que motivou a prescri&#231;&#227;o do exame&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Palpita&#231;&#245;es&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;8 &#40;53&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#44;7 &#40;963&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fadiga&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#44;7 &#40;94&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#44;3 &#40;650&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;827&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dispneia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;0 &#40;48&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;5 &#40;318&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;662&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tonturas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;0 &#40;36&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;5 &#40;488&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;ncope&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;2 &#40;31&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;5 &#40;360&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Confus&#227;o mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;3 &#40;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;3 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;743&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>ICC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;8 &#40;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;3 &#40;98&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;019&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>AVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;2 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;1 &#40;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;605&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Arritmia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;7 &#40;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;4 &#40;61&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;663&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fraqueza ou dificuldade na realiza&#231;&#227;o de exerc&#237;cio f&#237;sico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41&#44;7 &#40;250&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#44;7 &#40;708&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dor tor&#225;cica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;2 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;7 &#40;369&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Avalia&#231;&#227;o cardiovascular&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">30 &#40;180&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">31&#44;4 &#40;1331&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;496&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Extrassistolia e&#47;ou altera&#231;&#245;es eletrocardiogr&#225;ficas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;5 &#40;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;3 &#40;224&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Medica&#231;&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">96&#44;8 &#40;581&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">86&#44;8 &#40;3680&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diagn&#243;stico pr&#233;vio de FA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">57&#44;5 &#40;345&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;4 &#40;59&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diagn&#243;stico pr&#233;vio de FA parox&#237;stica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;0 &#40;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;4 &#40;102&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Sintomatologia do doente no exame&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Palpita&#231;&#245;es&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;8 &#40;23&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;1 &#40;385&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fadiga&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;5 &#40;27&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;8 &#40;205&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;721&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dispneia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;0 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;2 &#40;136&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tonturas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;0 &#40;24&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;2 &#40;264&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;031&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;ncope&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;3 &#40;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;2 &#40;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;370&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Confus&#227;o mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;0 &#40;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;0 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;707&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>ICC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;8 &#40;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;9 &#40;37&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;923&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Arritmia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;3 &#40;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;2 &#40;137&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;011&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dor tor&#225;cica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;8 &#40;17&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;8 &#40;332&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sem sintomas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84&#44;8 &#40;509&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">74&#44;7 &#40;3170&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Rela&#231;&#227;o entre o tra&#231;ado do Holter e a sintomatologia atual&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;3 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;7 &#40;284&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;138&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Caracter&#237;stica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Popula&#231;&#227;o FAP<span class="elsevierStyleHsp" style=""></span>&#43;<span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">flutter</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Popula&#231;&#227;o com FA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleBold">Sexo&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Masculino</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">51&#44;5 &#40;234&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;494&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Feminino</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">45&#44;2 &#40;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48&#44;5 &#40;220&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleBold">Grupo et&#225;rio&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">40&#8208;49 anos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;5 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;2 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">50&#8208;59 anos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;6 &#40;17&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;6 &#40;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">60&#8208;69 anos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#44;6 &#40;33&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&#44;3 &#40;92&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">70&#8208;79 anos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#44;9 &#40;51&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41&#44;4 &#40;188&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#62;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">80</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">23&#44;3 &#40;34&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">31&#44;5 &#40;143&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Per&#237;metro abdominal&#44; m&#233;dia cm &#40;DP&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">94&#44;9 &#40;10&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#44;8 &#40;11&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;480&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">IMC&#44; m&#233;dia kg&#47;m</span><span class="elsevierStyleSup"><span class="elsevierStyleItalic">2</span></span><span class="elsevierStyleItalic">&#40;DP&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#44;7 &#40;3&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27&#44;3 &#40;4&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;706&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleBold">Fatores de risco e hist&#243;ria de doen&#231;a cardiovascular&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Pr&#225;tica regular de exerc&#237;cio f&#237;sico</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#44;9 &#40;29&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13&#44;2 &#40;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;049&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">H&#225;bitos tab&#225;gicos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Nunca fumou&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#44;5 &#40;103&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">77&#44;1 &#40;350&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;108&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Ex&#8208;fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21&#44;9 &#40;32&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#44;2 &#40;87&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;5 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;7 &#40;17&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">H&#225;bitos alco&#243;licos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">47&#44;9 &#40;70&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">43&#44;6 &#40;198&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;360&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Hipertens&#227;o arterial</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59&#44;6 &#40;87&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">81&#44;7 &#40;371&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Dislipidemia</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">47&#44;3 &#40;69&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#44;4 &#40;238&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;358&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Diabetes</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14&#44;4 &#40;21&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&#44;5 &#40;93&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;225&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Hipertiroidismo</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;4 &#40;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;7 &#40;17&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;751&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">DPOC</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;2 &#40;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;0 &#40;32&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;692&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Hist&#243;ria familiar de doen&#231;a CV</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">37&#44;0 &#40;54&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">30&#44;0 &#40;136&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;176&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Hist&#243;ria de doen&#231;a cardiovascular</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>AVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59&#44;3 &#40;32&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41&#44;2 &#40;56&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;024&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>EAM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29&#44;6 &#40;16&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">36&#44;8 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;352&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Hist&#243;ria familiar</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Morte s&#250;bita&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;6 &#40;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;4 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;738&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Valvulopatia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;9 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;4 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;398&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Arritmia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24&#44;1 &#40;13&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27&#44;2 &#40;37&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;658&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Ocorr&#234;ncia de enfarte agudo do mioc&#225;rdio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;1 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;7 &#40;26&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;743&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Ocorr&#234;ncia de AVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;6 &#40;14&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;3 &#40;42&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;645&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleBold">Sintomatologia atual&#44; &#37; &#40;n&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Palpita&#231;&#245;es</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14&#44;4 &#40;21&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;0 &#40;32&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;007&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Fadiga</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&#44;3 &#40;18&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#44;7 &#40;76&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;202&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Dispneia</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;8 &#40;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;4 &#40;38&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;556&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Tonturas</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;8 &#40;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;4 &#40;29&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;481&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">S&#237;ncope</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;8 &#40;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;6 &#40;21&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;291&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Confus&#227;o mental</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;7 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;2 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;397&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">ICC</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;7 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;9 &#40;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;821&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">AVC</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;7 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;0 &#40;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;078&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Arritmia</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;1 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;9 &#40;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;008&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Fraqueza ou dificuldade na realiza&#231;&#227;o de exerc&#237;cio f&#237;sico</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#44;2 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">44&#44;1 &#40;200&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;037&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Dor tor&#225;cica</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;4 &#40;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;4 &#40;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;606&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Avalia&#231;&#227;o cardiovascular</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#44;6 &#40;49&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">28&#44;9 &#40;131&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;280&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Extrassistolia e&#47;ou altera&#231;&#245;es eletrocardiogr&#225;ficas</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;2 &#40;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;3 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Medica&#231;&#227;o&#44; &#37; &#40;n&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">93&#44;2 &#40;136&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">98&#44;0 &#40;445&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Diagn&#243;stico pr&#233;vio de FA&#44; &#37; &#40;n&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17&#44;1 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#44;5 &#40;320&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Diagn&#243;stico pr&#233;vio de FA parox&#237;stica&#44; &#37; &#40;n&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#44;4 &#40;24&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;3 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
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              "identificador" => "bib0080"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Increased risk of sudden and non&#8208;sudden cardiovascular death in patients with atrial fibrillation&#47;flutter following acute myocardial infarction"
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                        0 => array:3 [
                          "colaboracion" => "TRACE Study investigators"
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                          "autores" => array:3 [
                            0 => "O&#46;D&#46; Pedersen"
                            1 => "S&#46;Z&#46; Abildstrom"
                            2 => "M&#46;M&#46; Ottesen"
                          ]
                        ]
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                    0 => array:2 [
                      "doi" => "10.1093/eurheartj/ehi629"
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                        "tituloSerie" => "Eur Heart J&#46;"
                        "fecha" => "2006"
                        "volumen" => "27"
                        "paginaInicial" => "290"
                        "paginaFinal" => "295"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16267070"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib0085"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Independent risk factors for atrial fibrillation in a population&#8208;based cohort&#46; The Framingham Heart Study"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "E&#46;J&#46; Benjamin"
                            1 => "D&#46; Levy"
                            2 => "S&#46;M&#46; Varizi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
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                        "tituloSerie" => "JAMA&#46;"
                        "fecha" => "1994"
                        "volumen" => "271"
                        "paginaInicial" => "840"
                        "paginaFinal" => "844"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8114238"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0090"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Prospective community&#8208;based study of stroke in Northern Portugal&#58; incidence and case fatality in rural and urban populations"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
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                            2 => "I&#46; Matos"
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                    ]
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                      ]
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              "etiqueta" => "4"
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                            2 => "P&#46; Adrag&#227;o"
                          ]
                        ]
                      ]
                    ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Port Cardiol&#46;"
                        "fecha" => "2010"
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                        "paginaInicial" => "331"
                        "paginaFinal" => "350"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20635561"
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                        "paginaFinal" => "24"
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                    ]
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