array:26 [
  "pii" => "S0870255116303821"
  "issn" => "08702551"
  "doi" => "10.1016/j.repc.2016.12.011"
  "estado" => "S300"
  "fechaPublicacion" => "2017-07-01"
  "aid" => "1030"
  "copyright" => "Sociedade Portuguesa de Cardiologia"
  "copyrightAnyo" => "2017"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "dis"
  "cita" => "Rev Port Cardiol. 2017;36:547-9"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2405
    "formatos" => array:3 [
      "EPUB" => 188
      "HTML" => 1766
      "PDF" => 451
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:20 [
      "pii" => "S2174204917302076"
      "issn" => "21742049"
      "doi" => "10.1016/j.repce.2016.12.020"
      "estado" => "S300"
      "fechaPublicacion" => "2017-07-01"
      "aid" => "1030"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "dis"
      "cita" => "Rev Port Cardiol. 2017;36:547-9"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 1807
        "formatos" => array:3 [
          "EPUB" => 163
          "HTML" => 1321
          "PDF" => 323
        ]
      ]
      "en" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Editorial comment</span>"
        "titulo" => "Atrial fibrillation monitoring to reduce thromboembolic risk&#58; Selecting the patient and the monitoring device"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "547"
            "paginaFinal" => "549"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Monitoriza&#231;&#227;o eletrocardiogr&#225;fica para a redu&#231;&#227;o do risco tromboemb&#243;lico&#58; sele&#231;&#227;o do doente e do dispositivo de monitoriza&#231;&#227;o"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "S&#233;rgio Barra, Rui Provid&#234;ncia"
            "autores" => array:2 [
              0 => array:2 [
                "nombre" => "S&#233;rgio"
                "apellidos" => "Barra"
              ]
              1 => array:2 [
                "nombre" => "Rui"
                "apellidos" => "Provid&#234;ncia"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S0870255116303821"
          "doi" => "10.1016/j.repc.2016.12.011"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116303821?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917302076?idApp=UINPBA00004E"
      "url" => "/21742049/0000003600000078/v1_201707290050/S2174204917302076/v1_201707290050/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S0870255117302895"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2017.05.008"
    "estado" => "S300"
    "fechaPublicacion" => "2017-07-01"
    "aid" => "1025"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Cardiol. 2017;36:551-67"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 10468
      "formatos" => array:3 [
        "EPUB" => 224
        "HTML" => 6764
        "PDF" => 3480
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review Article</span>"
      "titulo" => "Aspirin and blood pressure&#58; Effects when used alone or in combination with antihypertensive drugs"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "551"
          "paginaFinal" => "567"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Aspirina e press&#227;o arterial&#58; efeitos do uso isolado ou em associa&#231;&#227;o com f&#225;rmacos anti-hipertensores"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 2065
              "Ancho" => 3000
              "Tamanyo" => 238970
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Biosynthesis of aspirin-triggered resolvins and protectin&#46; 5-LOX&#58; 5-lipoxygenase&#59; 17R-HDHA&#58; 17R-hydroxydocosahexaenoic acid&#59; 18R-HETE&#58; 18R-hydroxyeicosapentaenoic acid&#59; AT-RvD1&#58; aspirin-triggered resolvin D1&#59; AT-RvD2&#58; aspirin-triggered resolvin D2&#59; AT-RvD3&#58; aspirin-triggered resolvin D3&#59; AT-RvD4&#58; aspirin-triggered resolvin D4&#59; AT-PD&#58; aspirin-triggered protectin D&#59; COX-2&#58; cyclooxygenase-2&#59; DHA&#58; docosahexaenoic acid&#59; EPA&#58; eicosapentaenoic acid&#59; RvE1&#58; resolvin E1&#59; RvE2&#58; resolvin E2&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Ana Catarina Costa, Marta Reina-Couto, Ant&#243;nio Albino-Teixeira, Teresa Sousa"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Ana Catarina"
              "apellidos" => "Costa"
            ]
            1 => array:2 [
              "nombre" => "Marta"
              "apellidos" => "Reina-Couto"
            ]
            2 => array:2 [
              "nombre" => "Ant&#243;nio"
              "apellidos" => "Albino-Teixeira"
            ]
            3 => array:2 [
              "nombre" => "Teresa"
              "apellidos" => "Sousa"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2174204917302088"
        "doi" => "10.1016/j.repce.2017.05.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917302088?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117302895?idApp=UINPBA00004E"
    "url" => "/08702551/0000003600000078/v1_201707241250/S0870255117302895/v1_201707241250/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S0870255117301270"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2016.11.005"
    "estado" => "S300"
    "fechaPublicacion" => "2017-07-01"
    "aid" => "964"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Cardiol. 2017;36:535-46"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 6581
      "formatos" => array:3 [
        "EPUB" => 223
        "HTML" => 5711
        "PDF" => 647
      ]
    ]
    "pt" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Artigo Original</span>"
      "titulo" => "Preval&#234;ncia da fibrilha&#231;&#227;o auricular parox&#237;stica numa popula&#231;&#227;o avaliada por monitoriza&#231;&#227;o cont&#237;nua de 24 horas"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "535"
          "paginaFinal" => "546"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Prevalence of paroxysmal atrial fibrillation in a population assessed by continuous 24&#8208;hour monitoring"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jo&#227;o Primo, Helena Gon&#231;alves, Ana Macedo, Paula Russo, Telma Monteiro, Jo&#227;o Guimar&#227;es, Ov&#237;dio Costa"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Jo&#227;o"
              "apellidos" => "Primo"
            ]
            1 => array:2 [
              "nombre" => "Helena"
              "apellidos" => "Gon&#231;alves"
            ]
            2 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Macedo"
            ]
            3 => array:2 [
              "nombre" => "Paula"
              "apellidos" => "Russo"
            ]
            4 => array:2 [
              "nombre" => "Telma"
              "apellidos" => "Monteiro"
            ]
            5 => array:2 [
              "nombre" => "Jo&#227;o"
              "apellidos" => "Guimar&#227;es"
            ]
            6 => array:2 [
              "nombre" => "Ov&#237;dio"
              "apellidos" => "Costa"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S217420491730199X"
        "doi" => "10.1016/j.repce.2016.11.013"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217420491730199X?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117301270?idApp=UINPBA00004E"
    "url" => "/08702551/0000003600000078/v1_201707241250/S0870255117301270/v1_201707241250/pt/main.assets"
  ]
  "asociados" => array:1 [
    0 => array:20 [
      "pii" => "S0870255117301270"
      "issn" => "08702551"
      "doi" => "10.1016/j.repc.2016.11.005"
      "estado" => "S300"
      "fechaPublicacion" => "2017-07-01"
      "aid" => "964"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Rev Port Cardiol. 2017;36:535-46"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 6581
        "formatos" => array:3 [
          "EPUB" => 223
          "HTML" => 5711
          "PDF" => 647
        ]
      ]
      "pt" => array:12 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Artigo Original</span>"
        "titulo" => "Preval&#234;ncia da fibrilha&#231;&#227;o auricular parox&#237;stica numa popula&#231;&#227;o avaliada por monitoriza&#231;&#227;o cont&#237;nua de 24 horas"
        "tienePdf" => "pt"
        "tieneTextoCompleto" => "pt"
        "tieneResumen" => array:2 [
          0 => "pt"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "535"
            "paginaFinal" => "546"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Prevalence of paroxysmal atrial fibrillation in a population assessed by continuous 24&#8208;hour monitoring"
          ]
        ]
        "contieneResumen" => array:2 [
          "pt" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "pt" => true
        ]
        "contienePdf" => array:1 [
          "pt" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jo&#227;o Primo, Helena Gon&#231;alves, Ana Macedo, Paula Russo, Telma Monteiro, Jo&#227;o Guimar&#227;es, Ov&#237;dio Costa"
            "autores" => array:7 [
              0 => array:2 [
                "nombre" => "Jo&#227;o"
                "apellidos" => "Primo"
              ]
              1 => array:2 [
                "nombre" => "Helena"
                "apellidos" => "Gon&#231;alves"
              ]
              2 => array:2 [
                "nombre" => "Ana"
                "apellidos" => "Macedo"
              ]
              3 => array:2 [
                "nombre" => "Paula"
                "apellidos" => "Russo"
              ]
              4 => array:2 [
                "nombre" => "Telma"
                "apellidos" => "Monteiro"
              ]
              5 => array:2 [
                "nombre" => "Jo&#227;o"
                "apellidos" => "Guimar&#227;es"
              ]
              6 => array:2 [
                "nombre" => "Ov&#237;dio"
                "apellidos" => "Costa"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "pt"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S217420491730199X"
          "doi" => "10.1016/j.repce.2016.11.013"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217420491730199X?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117301270?idApp=UINPBA00004E"
      "url" => "/08702551/0000003600000078/v1_201707241250/S0870255117301270/v1_201707241250/pt/main.assets"
    ]
  ]
  "en" => array:12 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Editorial comment</span>"
    "titulo" => "Atrial fibrillation monitoring to reduce thromboembolic risk&#58; Selecting the patient and the monitoring device"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "547"
        "paginaFinal" => "549"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "S&#233;rgio Barra, Rui Provid&#234;ncia"
        "autores" => array:2 [
          0 => array:4 [
            "nombre" => "S&#233;rgio"
            "apellidos" => "Barra"
            "email" => array:1 [
              0 => "sergioncbarra&#64;gmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Rui"
            "apellidos" => "Provid&#234;ncia"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Cardiology Department&#44; Papworth Hospital NHS Foundation Trust&#44; Cambridge&#44; UK"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Barts Heart Centre&#44; Barts Health NHS Trust&#44; London&#44; UK"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Monitoriza&#231;&#227;o eletrocardiogr&#225;fica para a redu&#231;&#227;o do risco tromboemb&#243;lico&#58; sele&#231;&#227;o do doente e do dispositivo de monitoriza&#231;&#227;o"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Atrial fibrillation &#40;AF&#41; is the most common sustained cardiac arrhythmia and is associated with a five-fold increased risk of stroke&#46; At least 15-20&#37; of strokes are attributed to underlying AF&#44; but subclinical AF may be the cause of an additional number of cerebrovascular events&#46; Data from cardiac implantable electronic devices &#40;CIEDs&#41; have shown that subclinical atrial tachyarrhythmias lasting more than six minutes are associated with increased risk of thromboembolism&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">1</span></a> The often silent and intermittent nature of AF poses a problem&#59; more than half of AF episodes are asymptomatic<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">2&#44;3</span></a> and therefore identifying patients at risk remains a challenge&#46; This is a good illustration of the importance of AF monitoring&#46; Continuous monitoring with implantable cardiac monitors is now widely used in patients with cryptogenic stroke to identify those with silent AF who warrant antithrombotic therapy&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">4</span></a> In this context&#44; the prevalence of AF is approximately 20&#37;&#46; Stroke guidelines state that prolonged rhythm monitoring for AF of approximately 30 days is reasonable within six months of a cerebrovascular event with no apparent cause&#46;<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">5</span></a> In addition to risk stratification for stroke prevention&#44; AF monitoring and detection is also useful to assess the efficacy of rhythm control strategies&#44; prevent inappropriate shocks in implantable cardioverter-defibrillator &#40;ICD&#41; patients and maximize the benefit of cardiac resynchronization therapy &#40;CRT&#41;&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Detection of subclinical atrial tachyarrhythmias can be performed through a variety of tools&#44; including external surface monitoring with intermittent 12-lead electrocardiogram&#44; ambulatory Holter monitors&#44; cardiac event recorders&#44; portable electrocardiogram recorders &#40;such as AliveCor&#41; and the more recent adhesive patch electrocardiographic monitors&#44; as well as CIEDs such as implantable loop recorders&#44; dual-chamber pacemakers or ICDs and CRT devices&#46; Although longer-term Holter and event recorders have superior diagnostic yield compared to intermittent 12-lead ECGs&#44;<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">6</span></a> the need for a transmitter device and lower patient compliance represent limitations&#46; Patient compliance diminishes as the nominal monitoring duration increases&#44; owing to concerns regarding skin irritation and the inconvenience of performing daily activities while wearing a monitor&#46; More recent methods include simpler patch-type monitors which provide instant feedback and may lead to immediate changes in medical management&#46; In patients with CIEDs&#44; the possibility of continuous long-term monitoring increases the monitoring sensitivity&#46; In the setting of post-cryptogenic stroke&#44; long-term continuous monitoring with an implantable cardiac monitor has been shown to be superior in detecting AF to any intermittent monitoring strategy&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">7</span></a> However&#44; their applicability is hampered by the need for an invasive procedure&#46; Ideally&#44; the optimal monitoring device should be non-invasive&#44; inexpensive&#44; simple to use and able to provide continuous long-term monitoring with immediate feedback&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">In this issue of the <span class="elsevierStyleItalic">Journal</span>&#44; Primo et al&#46; have elegantly provided an assessment of the prevalence of AF&#44; based on episodes of atrial arrhythmia lasting for more than 30 seconds&#44; obtained through a 12-lead Holter monitor&#46;<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">8</span></a> Their study cohort included patients referred for Holter monitoring for a variety of reasons&#44; as determined by their general practitioners&#46; The main strengths of this study are &#40;1&#41; its prospective nature&#44; &#40;2&#41; the use of 12-lead electrocardiographic monitoring&#44; which enables more accurate determination of the underlying rhythm &#40;with potential therapeutic implications&#41; compared to the standard three-lead Holter&#44; &#40;3&#41; continuous 24-hour monitoring&#44; as opposed to a single 12-lead ECG as used in the FAMA study&#44;<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">9</span></a> with improved diagnostic yield&#44; &#40;4&#41; the inclusion of a relatively unbiased population of patients seen due to a variety of cardiovascular symptoms&#44; enabling a more accurate representation of AF prevalence in this context&#44; &#40;5&#41; an independent and blinded analysis by up to three different electrophysiologists&#44; and &#40;6&#41; the large size of the study sample&#44; allowing narrow 95&#37; confidence intervals&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Several important observations can be made on the results of this study&#46; Firstly&#44; more than 10 out of 100 patients participating in this study had documented AF or atrial flutter &#40;of which one fifth with paroxysmal AF&#41;&#46; This figure is higher than previously reported in both European and American studies&#44;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">10&#44;11</span></a> although AF prevalence in individuals aged 80 years or older may indeed be well above 10&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">10</span></a> In 2010&#44; the number of adults aged &#8805;55 years with AF corresponded to 1&#46;8&#37; of the total European Union population&#44; and this figure will rise to 3&#46;5&#37; by 2060&#46; This increase will be particularly dramatic in adults aged over 75&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">12</span></a> The higher prevalence of AF in the present study is likely a result of the criteria used for patient selection&#46; A higher AF prevalence should be expected in patients who present with cardiovascular symptoms&#44; even if non-specific&#44; compared to a cohort of asymptomatic patients&#46; However&#44; this study does provide us with a reasonably accurate estimate of AF prevalence among symptomatic patients who are typically seen by their general practitioners&#46; The number may be higher in the context of a more specialized cardiology outpatient clinic&#46; It is also noteworthy that advances in treatment for chronic cardiac and non-cardiac conditions&#44; aging populations&#44; and improved ability to diagnose AF through a wider range of monitoring devices may explain the higher prevalence of AF in more recent studies compared with older ones&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Secondly&#44; the vast majority of patients with documented paroxysmal AF had never had any ECG documentation of this arrhythmia and hence only a minority of these were anticoagulated&#46; As the authors state&#44; the very low use of anticoagulation is mainly a reflection of an undiagnosed cohort&#44; although faulty judgments on the risk of bleeding&#44; especially in elderly patients&#44; also help explain the low rate of anticoagulation prescription in AF patients&#44; as shown in the Portuguese setting&#46;<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">13</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">In patients with cardiovascular symptoms&#44; manual pulse palpation should be performed to determine the presence of an irregular pulse that could indicate underlying AF&#46; A 12-lead electrocardiogram should then be performed on all patients in whom a diagnosis of AF is suspected based on the detection of an irregular pulse&#46; The present study demonstrates that 24-hour Holter should also be considered for all of these patients&#44; with consideration of longer monitoring in patients whose characteristics may put them at higher risk of AF&#58; male gender&#44; advanced age&#44; or a history of hypertension&#44; chronic obstructive pulmonary disease&#44; cerebrovascular or ischemic heart disease&#46; Likewise&#44; a large waist circumference&#44; sedentary lifestyle and high alcohol intake are also predictors of AF&#46; Young age should not preclude appropriate investigation&#44; as AF is seen throughout all age strata&#44; as this study shows&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Notwithstanding the unequivocal merit of this study&#44; we should point out that&#44; in patients considered to be at high risk of AF&#44; and especially those who have sustained a cerebrovascular event&#44; 24-hour Holter monitoring may be insufficient&#46; It is well established that the longer a patient is monitored &#40;and this is not exclusive to implantable cardiac monitors&#41;&#44; the greater the likelihood of detecting sustained atrial arrhythmias including asymptomatic AF&#44; with subsequent impact on the rate of anticoagulation prescription&#46;<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">14&#44;15</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">The role of AF monitoring for the selection of patients who could benefit from catheter ablation is much less straightforward&#46; AF ablation is mostly indicated in symptomatic patients for quality-of-life purposes&#46; AF ablation in asymptomatic patients is not generally recommended&#44; and this is unlikely to change in the near future unless studies such as the Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation &#40;CABANA&#41; trial demonstrate that successful AF ablation can lead to decreased long-term risk of mortality or stroke compared with medical management&#46; Despite promising results by Di Biase et al&#46; in a recent study of heart failure patients with AF&#44;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">16</span></a> all other evidence supporting the utility of AF ablation in stroke or mortality risk reduction is based on observational data&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">To summarize&#44; 24-hour 12-lead Holter monitors are an elegant screening method for patients with a multitude of cardiovascular symptoms&#44; enabling detection of paroxysmal AF or atrial flutter in a non-negligible percentage of patients&#46; In patients with risk factors for AF and especially a recent history of thromboembolism&#44; more prolonged or long-term continuous AF monitoring should be performed wherever possible&#46; Even short-lasting atrial arrhythmias carry a significantly increased risk of thromboembolism and therefore any documented AF of at least a few minutes should lead to consideration of oral anticoagulation prophylaxis as per the CHA<span class="elsevierStyleInf">2</span>DS<span class="elsevierStyleInf">2</span>-VASc score&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:16 [
            0 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Subclinical atrial fibrillation and the risk of stroke"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "ASSERT Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46;S&#46; Healey"
                            1 => "S&#46;J&#46; Connolly"
                            2 => "M&#46;R&#46; Gold"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa1105575"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2012"
                        "volumen" => "366"
                        "paginaInicial" => "120"
                        "paginaFinal" => "129"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22236222"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Suppression of paroxysmal atrial tachyarrhythmias &#8211; results of the SOPAT trial"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "SOPAT Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Patten"
                            1 => "R&#46; Maas"
                            2 => "P&#46; Bauer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ehj.2004.06.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2004"
                        "volumen" => "25"
                        "paginaInicial" => "1395"
                        "paginaFinal" => "1404"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15321697"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of atrial fibrillation after cardioversion&#58; results of the PAFAC trial"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "Prevention of Atrial Fibrillation after Cardioversion Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46; Fetsch"
                            1 => "P&#46; Bauer"
                            2 => "R&#46; Engberding"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ehj.2004.04.015"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2004"
                        "volumen" => "25"
                        "paginaInicial" => "1385"
                        "paginaFinal" => "1394"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15302102"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Occult atrial fibrillation in cryptogenic stroke&#58; detection by 7-day electrocardiogram versus implantable cardiac monitors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "Ritter"
                            1 => "A&#46; Martin"
                            2 => "T&#46; Duning"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.111.676189"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke"
                        "fecha" => "2013"
                        "volumen" => "44"
                        "paginaInicial" => "1449"
                        "paginaFinal" => "1452"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23449264"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack&#58; a guideline for healthcare professionals from the American Heart Association&#47;American Stroke Association"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "W&#46;N&#46; Kernan"
                            1 => "B&#46; Ovbiagele"
                            2 => "H&#46;R&#46; Black"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STR.0000000000000024"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke"
                        "fecha" => "2014"
                        "volumen" => "45"
                        "paginaInicial" => "2160"
                        "paginaFinal" => "2236"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24788967"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frequent and prolonged asymptomatic episodes of paroxysmal atrial fibrillation revealed by automatic long-term event recorders in patients with a negative 24-hour Holter"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "F&#46; Roche"
                            1 => "J&#46;M&#46; Gaspoz"
                            2 => "A&#46; Da Costa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pacing Clin Electrophysiol"
                        "fecha" => "2002"
                        "volumen" => "25"
                        "paginaInicial" => "1587"
                        "paginaFinal" => "1593"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12494616"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of atrial fibrillation monitoring strategies after cryptogenic stroke &#40;from the Cryptogenic Stroke and Underlying AF Trial&#41;"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "CRYSTAL-AF Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "W&#46;C&#46; Choe"
                            1 => "R&#46;S&#46; Passman"
                            2 => "J&#46; Brachmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.amjcard.2015.06.012"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Cardiol"
                        "fecha" => "2015"
                        "volumen" => "116"
                        "paginaInicial" => "889"
                        "paginaFinal" => "893"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26183793"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preval&#234;ncia da fibrilha&#231;&#227;o auricular parox&#237;stica numa popula&#231;&#227;o avaliada por monitoriza&#231;&#227;o cont&#237;nua de 24 horas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46; Primo"
                            1 => "H&#46; Gon&#231;alves"
                            2 => "A&#46; Macedo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Port Cardiol"
                        "fecha" => "2017"
                        "volumen" => "36"
                        "paginaInicial" => "535"
                        "paginaFinal" => "546"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of atrial fibrillation in the Portuguese population aged 40 and over&#58; the FAMA study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Bonhorst"
                            1 => "M&#46; Mendes"
                            2 => "P&#46; Adragao"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Port Cardiol"
                        "fecha" => "2010"
                        "volumen" => "29"
                        "paginaInicial" => "331"
                        "paginaFinal" => "350"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20635561"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of atrial fibrillation&#58; European perspective"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Zoni-Berisso"
                            1 => "F&#46; Lercari"
                            2 => "T&#46; Carazza"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2147/CLEP.S47385"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Epidemiol"
                        "fecha" => "2014"
                        "volumen" => "6"
                        "paginaInicial" => "213"
                        "paginaFinal" => "220"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24966695"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology and significance of atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46;M&#46; Ryder"
                            1 => "E&#46;J&#46; Benjamin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Cardiol"
                        "fecha" => "1999"
                        "volumen" => "84"
                        "paginaInicial" => "131R"
                        "paginaFinal" => "138R"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10568672"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Projections on the number of individuals with atrial fibrillation in the European Union&#44; from 2000 to 2060"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46;P&#46; Krijthe"
                            1 => "A&#46; Kunst"
                            2 => "E&#46;J&#46; Benjamin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/eurheartj/eht280"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2013"
                        "volumen" => "34"
                        "paginaInicial" => "2746"
                        "paginaFinal" => "2751"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23900699"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prevalence of oral anticoagulation in patients with atrial fibrillation in Portugal&#58; systematic review and meta-analysis of observational studies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D&#46; Caldeira"
                            1 => "M&#46; Barra"
                            2 => "C&#46; David"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.repc.2014.02.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Port Cardiol"
                        "fecha" => "2014"
                        "volumen" => "33"
                        "paginaInicial" => "555"
                        "paginaFinal" => "560"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25240861"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cryptogenic stroke and underlying atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "CRYSTAL AF Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46; Sanna"
                            1 => "H&#46;C&#46; Diener"
                            2 => "R&#46;S&#46; Passman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa1313600"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2014"
                        "volumen" => "370"
                        "paginaInicial" => "2478"
                        "paginaFinal" => "2486"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24963567"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atrial fibrillation in patients with cryptogenic stroke"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "EMBRACE Investigators and Coordinators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D&#46;J&#46; Gladstone"
                            1 => "M&#46; Spring"
                            2 => "P&#46; Dorian"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa1311376"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2014"
                        "volumen" => "370"
                        "paginaInicial" => "2467"
                        "paginaFinal" => "2477"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24963566"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ablation versus amiodarone for treatment of persistent atrial fibrillation in patients with congestive heart failure and an implanted device&#58; results from the AATAC Multicenter Randomized Trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46; Di Biase"
                            1 => "P&#46; Mohanty"
                            2 => "S&#46; Mohanty"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/CIRCULATIONAHA.115.019406"
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "2016"
                        "volumen" => "133"
                        "paginaInicial" => "1637"
                        "paginaFinal" => "1644"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27029350"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/08702551/0000003600000078/v1_201707241250/S0870255116303821/v1_201707241250/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "29261"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Artigos Originais"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08702551/0000003600000078/v1_201707241250/S0870255116303821/v1_201707241250/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116303821?idApp=UINPBA00004E"
]
Partilhar
Informação da revista

Estatísticas

Siga este link para acessar o texto completo do artigo

Editorial comment
Atrial fibrillation monitoring to reduce thromboembolic risk: Selecting the patient and the monitoring device
Monitorização eletrocardiográfica para a redução do risco tromboembólico: seleção do doente e do dispositivo de monitorização
Sérgio Barraa,
Autor para correspondência
sergioncbarra@gmail.com

Corresponding author.
, Rui Providênciab
a Cardiology Department, Papworth Hospital NHS Foundation Trust, Cambridge, UK
b Barts Heart Centre, Barts Health NHS Trust, London, UK
Lido
5536
Vezes
que se leu este artigo
1882
Total PDF
3654
Total HTML
Compartilhar estatísticas
 array:26 [
  "pii" => "S0870255116303821"
  "issn" => "08702551"
  "doi" => "10.1016/j.repc.2016.12.011"
  "estado" => "S300"
  "fechaPublicacion" => "2017-07-01"
  "aid" => "1030"
  "copyright" => "Sociedade Portuguesa de Cardiologia"
  "copyrightAnyo" => "2017"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "dis"
  "cita" => "Rev Port Cardiol. 2017;36:547-9"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2405
    "formatos" => array:3 [
      "EPUB" => 188
      "HTML" => 1766
      "PDF" => 451
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:20 [
      "pii" => "S2174204917302076"
      "issn" => "21742049"
      "doi" => "10.1016/j.repce.2016.12.020"
      "estado" => "S300"
      "fechaPublicacion" => "2017-07-01"
      "aid" => "1030"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "dis"
      "cita" => "Rev Port Cardiol. 2017;36:547-9"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 1807
        "formatos" => array:3 [
          "EPUB" => 163
          "HTML" => 1321
          "PDF" => 323
        ]
      ]
      "en" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Editorial comment</span>"
        "titulo" => "Atrial fibrillation monitoring to reduce thromboembolic risk&#58; Selecting the patient and the monitoring device"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "547"
            "paginaFinal" => "549"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Monitoriza&#231;&#227;o eletrocardiogr&#225;fica para a redu&#231;&#227;o do risco tromboemb&#243;lico&#58; sele&#231;&#227;o do doente e do dispositivo de monitoriza&#231;&#227;o"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "S&#233;rgio Barra, Rui Provid&#234;ncia"
            "autores" => array:2 [
              0 => array:2 [
                "nombre" => "S&#233;rgio"
                "apellidos" => "Barra"
              ]
              1 => array:2 [
                "nombre" => "Rui"
                "apellidos" => "Provid&#234;ncia"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S0870255116303821"
          "doi" => "10.1016/j.repc.2016.12.011"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116303821?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917302076?idApp=UINPBA00004E"
      "url" => "/21742049/0000003600000078/v1_201707290050/S2174204917302076/v1_201707290050/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S0870255117302895"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2017.05.008"
    "estado" => "S300"
    "fechaPublicacion" => "2017-07-01"
    "aid" => "1025"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Cardiol. 2017;36:551-67"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 10468
      "formatos" => array:3 [
        "EPUB" => 224
        "HTML" => 6764
        "PDF" => 3480
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review Article</span>"
      "titulo" => "Aspirin and blood pressure&#58; Effects when used alone or in combination with antihypertensive drugs"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "551"
          "paginaFinal" => "567"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Aspirina e press&#227;o arterial&#58; efeitos do uso isolado ou em associa&#231;&#227;o com f&#225;rmacos anti-hipertensores"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 2065
              "Ancho" => 3000
              "Tamanyo" => 238970
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Biosynthesis of aspirin-triggered resolvins and protectin&#46; 5-LOX&#58; 5-lipoxygenase&#59; 17R-HDHA&#58; 17R-hydroxydocosahexaenoic acid&#59; 18R-HETE&#58; 18R-hydroxyeicosapentaenoic acid&#59; AT-RvD1&#58; aspirin-triggered resolvin D1&#59; AT-RvD2&#58; aspirin-triggered resolvin D2&#59; AT-RvD3&#58; aspirin-triggered resolvin D3&#59; AT-RvD4&#58; aspirin-triggered resolvin D4&#59; AT-PD&#58; aspirin-triggered protectin D&#59; COX-2&#58; cyclooxygenase-2&#59; DHA&#58; docosahexaenoic acid&#59; EPA&#58; eicosapentaenoic acid&#59; RvE1&#58; resolvin E1&#59; RvE2&#58; resolvin E2&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Ana Catarina Costa, Marta Reina-Couto, Ant&#243;nio Albino-Teixeira, Teresa Sousa"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Ana Catarina"
              "apellidos" => "Costa"
            ]
            1 => array:2 [
              "nombre" => "Marta"
              "apellidos" => "Reina-Couto"
            ]
            2 => array:2 [
              "nombre" => "Ant&#243;nio"
              "apellidos" => "Albino-Teixeira"
            ]
            3 => array:2 [
              "nombre" => "Teresa"
              "apellidos" => "Sousa"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2174204917302088"
        "doi" => "10.1016/j.repce.2017.05.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204917302088?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117302895?idApp=UINPBA00004E"
    "url" => "/08702551/0000003600000078/v1_201707241250/S0870255117302895/v1_201707241250/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S0870255117301270"
    "issn" => "08702551"
    "doi" => "10.1016/j.repc.2016.11.005"
    "estado" => "S300"
    "fechaPublicacion" => "2017-07-01"
    "aid" => "964"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Cardiol. 2017;36:535-46"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 6581
      "formatos" => array:3 [
        "EPUB" => 223
        "HTML" => 5711
        "PDF" => 647
      ]
    ]
    "pt" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Artigo Original</span>"
      "titulo" => "Preval&#234;ncia da fibrilha&#231;&#227;o auricular parox&#237;stica numa popula&#231;&#227;o avaliada por monitoriza&#231;&#227;o cont&#237;nua de 24 horas"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "535"
          "paginaFinal" => "546"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Prevalence of paroxysmal atrial fibrillation in a population assessed by continuous 24&#8208;hour monitoring"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jo&#227;o Primo, Helena Gon&#231;alves, Ana Macedo, Paula Russo, Telma Monteiro, Jo&#227;o Guimar&#227;es, Ov&#237;dio Costa"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Jo&#227;o"
              "apellidos" => "Primo"
            ]
            1 => array:2 [
              "nombre" => "Helena"
              "apellidos" => "Gon&#231;alves"
            ]
            2 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Macedo"
            ]
            3 => array:2 [
              "nombre" => "Paula"
              "apellidos" => "Russo"
            ]
            4 => array:2 [
              "nombre" => "Telma"
              "apellidos" => "Monteiro"
            ]
            5 => array:2 [
              "nombre" => "Jo&#227;o"
              "apellidos" => "Guimar&#227;es"
            ]
            6 => array:2 [
              "nombre" => "Ov&#237;dio"
              "apellidos" => "Costa"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S217420491730199X"
        "doi" => "10.1016/j.repce.2016.11.013"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217420491730199X?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117301270?idApp=UINPBA00004E"
    "url" => "/08702551/0000003600000078/v1_201707241250/S0870255117301270/v1_201707241250/pt/main.assets"
  ]
  "asociados" => array:1 [
    0 => array:20 [
      "pii" => "S0870255117301270"
      "issn" => "08702551"
      "doi" => "10.1016/j.repc.2016.11.005"
      "estado" => "S300"
      "fechaPublicacion" => "2017-07-01"
      "aid" => "964"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Rev Port Cardiol. 2017;36:535-46"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 6581
        "formatos" => array:3 [
          "EPUB" => 223
          "HTML" => 5711
          "PDF" => 647
        ]
      ]
      "pt" => array:12 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Artigo Original</span>"
        "titulo" => "Preval&#234;ncia da fibrilha&#231;&#227;o auricular parox&#237;stica numa popula&#231;&#227;o avaliada por monitoriza&#231;&#227;o cont&#237;nua de 24 horas"
        "tienePdf" => "pt"
        "tieneTextoCompleto" => "pt"
        "tieneResumen" => array:2 [
          0 => "pt"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "535"
            "paginaFinal" => "546"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Prevalence of paroxysmal atrial fibrillation in a population assessed by continuous 24&#8208;hour monitoring"
          ]
        ]
        "contieneResumen" => array:2 [
          "pt" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "pt" => true
        ]
        "contienePdf" => array:1 [
          "pt" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jo&#227;o Primo, Helena Gon&#231;alves, Ana Macedo, Paula Russo, Telma Monteiro, Jo&#227;o Guimar&#227;es, Ov&#237;dio Costa"
            "autores" => array:7 [
              0 => array:2 [
                "nombre" => "Jo&#227;o"
                "apellidos" => "Primo"
              ]
              1 => array:2 [
                "nombre" => "Helena"
                "apellidos" => "Gon&#231;alves"
              ]
              2 => array:2 [
                "nombre" => "Ana"
                "apellidos" => "Macedo"
              ]
              3 => array:2 [
                "nombre" => "Paula"
                "apellidos" => "Russo"
              ]
              4 => array:2 [
                "nombre" => "Telma"
                "apellidos" => "Monteiro"
              ]
              5 => array:2 [
                "nombre" => "Jo&#227;o"
                "apellidos" => "Guimar&#227;es"
              ]
              6 => array:2 [
                "nombre" => "Ov&#237;dio"
                "apellidos" => "Costa"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "pt"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S217420491730199X"
          "doi" => "10.1016/j.repce.2016.11.013"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217420491730199X?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117301270?idApp=UINPBA00004E"
      "url" => "/08702551/0000003600000078/v1_201707241250/S0870255117301270/v1_201707241250/pt/main.assets"
    ]
  ]
  "en" => array:12 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Editorial comment</span>"
    "titulo" => "Atrial fibrillation monitoring to reduce thromboembolic risk&#58; Selecting the patient and the monitoring device"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "547"
        "paginaFinal" => "549"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "S&#233;rgio Barra, Rui Provid&#234;ncia"
        "autores" => array:2 [
          0 => array:4 [
            "nombre" => "S&#233;rgio"
            "apellidos" => "Barra"
            "email" => array:1 [
              0 => "sergioncbarra&#64;gmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Rui"
            "apellidos" => "Provid&#234;ncia"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Cardiology Department&#44; Papworth Hospital NHS Foundation Trust&#44; Cambridge&#44; UK"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Barts Heart Centre&#44; Barts Health NHS Trust&#44; London&#44; UK"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Monitoriza&#231;&#227;o eletrocardiogr&#225;fica para a redu&#231;&#227;o do risco tromboemb&#243;lico&#58; sele&#231;&#227;o do doente e do dispositivo de monitoriza&#231;&#227;o"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Atrial fibrillation &#40;AF&#41; is the most common sustained cardiac arrhythmia and is associated with a five-fold increased risk of stroke&#46; At least 15-20&#37; of strokes are attributed to underlying AF&#44; but subclinical AF may be the cause of an additional number of cerebrovascular events&#46; Data from cardiac implantable electronic devices &#40;CIEDs&#41; have shown that subclinical atrial tachyarrhythmias lasting more than six minutes are associated with increased risk of thromboembolism&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">1</span></a> The often silent and intermittent nature of AF poses a problem&#59; more than half of AF episodes are asymptomatic<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">2&#44;3</span></a> and therefore identifying patients at risk remains a challenge&#46; This is a good illustration of the importance of AF monitoring&#46; Continuous monitoring with implantable cardiac monitors is now widely used in patients with cryptogenic stroke to identify those with silent AF who warrant antithrombotic therapy&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">4</span></a> In this context&#44; the prevalence of AF is approximately 20&#37;&#46; Stroke guidelines state that prolonged rhythm monitoring for AF of approximately 30 days is reasonable within six months of a cerebrovascular event with no apparent cause&#46;<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">5</span></a> In addition to risk stratification for stroke prevention&#44; AF monitoring and detection is also useful to assess the efficacy of rhythm control strategies&#44; prevent inappropriate shocks in implantable cardioverter-defibrillator &#40;ICD&#41; patients and maximize the benefit of cardiac resynchronization therapy &#40;CRT&#41;&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Detection of subclinical atrial tachyarrhythmias can be performed through a variety of tools&#44; including external surface monitoring with intermittent 12-lead electrocardiogram&#44; ambulatory Holter monitors&#44; cardiac event recorders&#44; portable electrocardiogram recorders &#40;such as AliveCor&#41; and the more recent adhesive patch electrocardiographic monitors&#44; as well as CIEDs such as implantable loop recorders&#44; dual-chamber pacemakers or ICDs and CRT devices&#46; Although longer-term Holter and event recorders have superior diagnostic yield compared to intermittent 12-lead ECGs&#44;<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">6</span></a> the need for a transmitter device and lower patient compliance represent limitations&#46; Patient compliance diminishes as the nominal monitoring duration increases&#44; owing to concerns regarding skin irritation and the inconvenience of performing daily activities while wearing a monitor&#46; More recent methods include simpler patch-type monitors which provide instant feedback and may lead to immediate changes in medical management&#46; In patients with CIEDs&#44; the possibility of continuous long-term monitoring increases the monitoring sensitivity&#46; In the setting of post-cryptogenic stroke&#44; long-term continuous monitoring with an implantable cardiac monitor has been shown to be superior in detecting AF to any intermittent monitoring strategy&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">7</span></a> However&#44; their applicability is hampered by the need for an invasive procedure&#46; Ideally&#44; the optimal monitoring device should be non-invasive&#44; inexpensive&#44; simple to use and able to provide continuous long-term monitoring with immediate feedback&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">In this issue of the <span class="elsevierStyleItalic">Journal</span>&#44; Primo et al&#46; have elegantly provided an assessment of the prevalence of AF&#44; based on episodes of atrial arrhythmia lasting for more than 30 seconds&#44; obtained through a 12-lead Holter monitor&#46;<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">8</span></a> Their study cohort included patients referred for Holter monitoring for a variety of reasons&#44; as determined by their general practitioners&#46; The main strengths of this study are &#40;1&#41; its prospective nature&#44; &#40;2&#41; the use of 12-lead electrocardiographic monitoring&#44; which enables more accurate determination of the underlying rhythm &#40;with potential therapeutic implications&#41; compared to the standard three-lead Holter&#44; &#40;3&#41; continuous 24-hour monitoring&#44; as opposed to a single 12-lead ECG as used in the FAMA study&#44;<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">9</span></a> with improved diagnostic yield&#44; &#40;4&#41; the inclusion of a relatively unbiased population of patients seen due to a variety of cardiovascular symptoms&#44; enabling a more accurate representation of AF prevalence in this context&#44; &#40;5&#41; an independent and blinded analysis by up to three different electrophysiologists&#44; and &#40;6&#41; the large size of the study sample&#44; allowing narrow 95&#37; confidence intervals&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Several important observations can be made on the results of this study&#46; Firstly&#44; more than 10 out of 100 patients participating in this study had documented AF or atrial flutter &#40;of which one fifth with paroxysmal AF&#41;&#46; This figure is higher than previously reported in both European and American studies&#44;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">10&#44;11</span></a> although AF prevalence in individuals aged 80 years or older may indeed be well above 10&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">10</span></a> In 2010&#44; the number of adults aged &#8805;55 years with AF corresponded to 1&#46;8&#37; of the total European Union population&#44; and this figure will rise to 3&#46;5&#37; by 2060&#46; This increase will be particularly dramatic in adults aged over 75&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">12</span></a> The higher prevalence of AF in the present study is likely a result of the criteria used for patient selection&#46; A higher AF prevalence should be expected in patients who present with cardiovascular symptoms&#44; even if non-specific&#44; compared to a cohort of asymptomatic patients&#46; However&#44; this study does provide us with a reasonably accurate estimate of AF prevalence among symptomatic patients who are typically seen by their general practitioners&#46; The number may be higher in the context of a more specialized cardiology outpatient clinic&#46; It is also noteworthy that advances in treatment for chronic cardiac and non-cardiac conditions&#44; aging populations&#44; and improved ability to diagnose AF through a wider range of monitoring devices may explain the higher prevalence of AF in more recent studies compared with older ones&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Secondly&#44; the vast majority of patients with documented paroxysmal AF had never had any ECG documentation of this arrhythmia and hence only a minority of these were anticoagulated&#46; As the authors state&#44; the very low use of anticoagulation is mainly a reflection of an undiagnosed cohort&#44; although faulty judgments on the risk of bleeding&#44; especially in elderly patients&#44; also help explain the low rate of anticoagulation prescription in AF patients&#44; as shown in the Portuguese setting&#46;<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">13</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">In patients with cardiovascular symptoms&#44; manual pulse palpation should be performed to determine the presence of an irregular pulse that could indicate underlying AF&#46; A 12-lead electrocardiogram should then be performed on all patients in whom a diagnosis of AF is suspected based on the detection of an irregular pulse&#46; The present study demonstrates that 24-hour Holter should also be considered for all of these patients&#44; with consideration of longer monitoring in patients whose characteristics may put them at higher risk of AF&#58; male gender&#44; advanced age&#44; or a history of hypertension&#44; chronic obstructive pulmonary disease&#44; cerebrovascular or ischemic heart disease&#46; Likewise&#44; a large waist circumference&#44; sedentary lifestyle and high alcohol intake are also predictors of AF&#46; Young age should not preclude appropriate investigation&#44; as AF is seen throughout all age strata&#44; as this study shows&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Notwithstanding the unequivocal merit of this study&#44; we should point out that&#44; in patients considered to be at high risk of AF&#44; and especially those who have sustained a cerebrovascular event&#44; 24-hour Holter monitoring may be insufficient&#46; It is well established that the longer a patient is monitored &#40;and this is not exclusive to implantable cardiac monitors&#41;&#44; the greater the likelihood of detecting sustained atrial arrhythmias including asymptomatic AF&#44; with subsequent impact on the rate of anticoagulation prescription&#46;<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">14&#44;15</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">The role of AF monitoring for the selection of patients who could benefit from catheter ablation is much less straightforward&#46; AF ablation is mostly indicated in symptomatic patients for quality-of-life purposes&#46; AF ablation in asymptomatic patients is not generally recommended&#44; and this is unlikely to change in the near future unless studies such as the Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation &#40;CABANA&#41; trial demonstrate that successful AF ablation can lead to decreased long-term risk of mortality or stroke compared with medical management&#46; Despite promising results by Di Biase et al&#46; in a recent study of heart failure patients with AF&#44;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">16</span></a> all other evidence supporting the utility of AF ablation in stroke or mortality risk reduction is based on observational data&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">To summarize&#44; 24-hour 12-lead Holter monitors are an elegant screening method for patients with a multitude of cardiovascular symptoms&#44; enabling detection of paroxysmal AF or atrial flutter in a non-negligible percentage of patients&#46; In patients with risk factors for AF and especially a recent history of thromboembolism&#44; more prolonged or long-term continuous AF monitoring should be performed wherever possible&#46; Even short-lasting atrial arrhythmias carry a significantly increased risk of thromboembolism and therefore any documented AF of at least a few minutes should lead to consideration of oral anticoagulation prophylaxis as per the CHA<span class="elsevierStyleInf">2</span>DS<span class="elsevierStyleInf">2</span>-VASc score&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:16 [
            0 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Subclinical atrial fibrillation and the risk of stroke"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "ASSERT Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46;S&#46; Healey"
                            1 => "S&#46;J&#46; Connolly"
                            2 => "M&#46;R&#46; Gold"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa1105575"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2012"
                        "volumen" => "366"
                        "paginaInicial" => "120"
                        "paginaFinal" => "129"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22236222"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Suppression of paroxysmal atrial tachyarrhythmias &#8211; results of the SOPAT trial"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "SOPAT Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Patten"
                            1 => "R&#46; Maas"
                            2 => "P&#46; Bauer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ehj.2004.06.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2004"
                        "volumen" => "25"
                        "paginaInicial" => "1395"
                        "paginaFinal" => "1404"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15321697"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of atrial fibrillation after cardioversion&#58; results of the PAFAC trial"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "Prevention of Atrial Fibrillation after Cardioversion Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46; Fetsch"
                            1 => "P&#46; Bauer"
                            2 => "R&#46; Engberding"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ehj.2004.04.015"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2004"
                        "volumen" => "25"
                        "paginaInicial" => "1385"
                        "paginaFinal" => "1394"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15302102"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Occult atrial fibrillation in cryptogenic stroke&#58; detection by 7-day electrocardiogram versus implantable cardiac monitors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "Ritter"
                            1 => "A&#46; Martin"
                            2 => "T&#46; Duning"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.111.676189"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke"
                        "fecha" => "2013"
                        "volumen" => "44"
                        "paginaInicial" => "1449"
                        "paginaFinal" => "1452"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23449264"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack&#58; a guideline for healthcare professionals from the American Heart Association&#47;American Stroke Association"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "W&#46;N&#46; Kernan"
                            1 => "B&#46; Ovbiagele"
                            2 => "H&#46;R&#46; Black"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STR.0000000000000024"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke"
                        "fecha" => "2014"
                        "volumen" => "45"
                        "paginaInicial" => "2160"
                        "paginaFinal" => "2236"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24788967"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frequent and prolonged asymptomatic episodes of paroxysmal atrial fibrillation revealed by automatic long-term event recorders in patients with a negative 24-hour Holter"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "F&#46; Roche"
                            1 => "J&#46;M&#46; Gaspoz"
                            2 => "A&#46; Da Costa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pacing Clin Electrophysiol"
                        "fecha" => "2002"
                        "volumen" => "25"
                        "paginaInicial" => "1587"
                        "paginaFinal" => "1593"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12494616"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of atrial fibrillation monitoring strategies after cryptogenic stroke &#40;from the Cryptogenic Stroke and Underlying AF Trial&#41;"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "CRYSTAL-AF Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "W&#46;C&#46; Choe"
                            1 => "R&#46;S&#46; Passman"
                            2 => "J&#46; Brachmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.amjcard.2015.06.012"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Cardiol"
                        "fecha" => "2015"
                        "volumen" => "116"
                        "paginaInicial" => "889"
                        "paginaFinal" => "893"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26183793"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preval&#234;ncia da fibrilha&#231;&#227;o auricular parox&#237;stica numa popula&#231;&#227;o avaliada por monitoriza&#231;&#227;o cont&#237;nua de 24 horas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46; Primo"
                            1 => "H&#46; Gon&#231;alves"
                            2 => "A&#46; Macedo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Port Cardiol"
                        "fecha" => "2017"
                        "volumen" => "36"
                        "paginaInicial" => "535"
                        "paginaFinal" => "546"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of atrial fibrillation in the Portuguese population aged 40 and over&#58; the FAMA study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Bonhorst"
                            1 => "M&#46; Mendes"
                            2 => "P&#46; Adragao"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Port Cardiol"
                        "fecha" => "2010"
                        "volumen" => "29"
                        "paginaInicial" => "331"
                        "paginaFinal" => "350"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20635561"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of atrial fibrillation&#58; European perspective"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Zoni-Berisso"
                            1 => "F&#46; Lercari"
                            2 => "T&#46; Carazza"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2147/CLEP.S47385"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Epidemiol"
                        "fecha" => "2014"
                        "volumen" => "6"
                        "paginaInicial" => "213"
                        "paginaFinal" => "220"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24966695"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology and significance of atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46;M&#46; Ryder"
                            1 => "E&#46;J&#46; Benjamin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Cardiol"
                        "fecha" => "1999"
                        "volumen" => "84"
                        "paginaInicial" => "131R"
                        "paginaFinal" => "138R"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10568672"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Projections on the number of individuals with atrial fibrillation in the European Union&#44; from 2000 to 2060"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46;P&#46; Krijthe"
                            1 => "A&#46; Kunst"
                            2 => "E&#46;J&#46; Benjamin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/eurheartj/eht280"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2013"
                        "volumen" => "34"
                        "paginaInicial" => "2746"
                        "paginaFinal" => "2751"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23900699"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prevalence of oral anticoagulation in patients with atrial fibrillation in Portugal&#58; systematic review and meta-analysis of observational studies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D&#46; Caldeira"
                            1 => "M&#46; Barra"
                            2 => "C&#46; David"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.repc.2014.02.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Port Cardiol"
                        "fecha" => "2014"
                        "volumen" => "33"
                        "paginaInicial" => "555"
                        "paginaFinal" => "560"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25240861"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cryptogenic stroke and underlying atrial fibrillation"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "CRYSTAL AF Investigators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46; Sanna"
                            1 => "H&#46;C&#46; Diener"
                            2 => "R&#46;S&#46; Passman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa1313600"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2014"
                        "volumen" => "370"
                        "paginaInicial" => "2478"
                        "paginaFinal" => "2486"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24963567"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atrial fibrillation in patients with cryptogenic stroke"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "EMBRACE Investigators and Coordinators"
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D&#46;J&#46; Gladstone"
                            1 => "M&#46; Spring"
                            2 => "P&#46; Dorian"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa1311376"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2014"
                        "volumen" => "370"
                        "paginaInicial" => "2467"
                        "paginaFinal" => "2477"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24963566"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ablation versus amiodarone for treatment of persistent atrial fibrillation in patients with congestive heart failure and an implanted device&#58; results from the AATAC Multicenter Randomized Trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46; Di Biase"
                            1 => "P&#46; Mohanty"
                            2 => "S&#46; Mohanty"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/CIRCULATIONAHA.115.019406"
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "2016"
                        "volumen" => "133"
                        "paginaInicial" => "1637"
                        "paginaFinal" => "1644"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27029350"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/08702551/0000003600000078/v1_201707241250/S0870255116303821/v1_201707241250/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "29261"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Artigos Originais"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08702551/0000003600000078/v1_201707241250/S0870255116303821/v1_201707241250/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255116303821?idApp=UINPBA00004E"
]
Informação do artigo
ISSN: 08702551
Idioma original: Inglês
Dados atualizados diariamente
Ano/Mês Html Pdf Total
2024 Novembro 6 12 18
2024 Outubro 43 37 80
2024 Setembro 50 37 87
2024 Agosto 45 38 83
2024 Julho 32 33 65
2024 Junho 42 19 61
2024 Maio 35 18 53
2024 Abril 42 28 70
2024 Maro 33 22 55
2024 Fevereiro 40 22 62
2024 Janeiro 26 24 50
2023 Dezembro 25 28 53
2023 Novembro 31 32 63
2023 Outubro 18 17 35
2023 Setembro 19 19 38
2023 Agosto 30 15 45
2023 Julho 20 10 30
2023 Junho 20 12 32
2023 Maio 39 27 66
2023 Abril 23 8 31
2023 Maro 47 21 68
2023 Fevereiro 37 22 59
2023 Janeiro 16 24 40
2022 Dezembro 41 19 60
2022 Novembro 38 33 71
2022 Outubro 41 26 67
2022 Setembro 18 32 50
2022 Agosto 31 30 61
2022 Julho 31 41 72
2022 Junho 23 31 54
2022 Maio 26 39 65
2022 Abril 34 28 62
2022 Maro 29 34 63
2022 Fevereiro 21 32 53
2022 Janeiro 24 23 47
2021 Dezembro 20 44 64
2021 Novembro 30 31 61
2021 Outubro 44 51 95
2021 Setembro 27 34 61
2021 Agosto 25 30 55
2021 Julho 19 18 37
2021 Junho 24 31 55
2021 Maio 26 46 72
2021 Abril 43 32 75
2021 Maro 43 25 68
2021 Fevereiro 54 21 75
2021 Janeiro 41 14 55
2020 Dezembro 37 19 56
2020 Novembro 37 19 56
2020 Outubro 23 17 40
2020 Setembro 59 16 75
2020 Agosto 19 14 33
2020 Julho 62 8 70
2020 Junho 26 10 36
2020 Maio 37 16 53
2020 Abril 51 19 70
2020 Maro 50 15 65
2020 Fevereiro 50 18 68
2020 Janeiro 30 11 41
2019 Dezembro 28 6 34
2019 Novembro 53 6 59
2019 Outubro 40 11 51
2019 Setembro 27 10 37
2019 Agosto 23 11 34
2019 Julho 37 11 48
2019 Junho 53 19 72
2019 Maio 84 8 92
2019 Abril 31 18 49
2019 Maro 27 11 38
2019 Fevereiro 62 10 72
2019 Janeiro 17 8 25
2018 Dezembro 44 9 53
2018 Novembro 113 12 125
2018 Outubro 251 15 266
2018 Setembro 60 10 70
2018 Agosto 64 14 78
2018 Julho 44 8 52
2018 Junho 68 17 85
2018 Maio 49 13 62
2018 Abril 60 19 79
2018 Maro 68 14 82
2018 Fevereiro 27 4 31
2018 Janeiro 33 11 44
2017 Dezembro 46 21 67
2017 Novembro 67 24 91
2017 Outubro 47 23 70
2017 Setembro 53 21 74
2017 Agosto 88 35 123
2017 Julho 37 31 68
Mostrar tudo

Siga este link para acessar o texto completo do artigo

Idiomas
Revista Portuguesa de Cardiologia
en pt

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

Ao assinalar que é «Profissional de Saúde», declara conhecer e aceitar que a responsável pelo tratamento dos dados pessoais dos utilizadores da página de internet da Revista Portuguesa de Cardiologia (RPC), é esta entidade, com sede no Campo Grande, n.º 28, 13.º, 1700-093 Lisboa, com os telefones 217 970 685 e 217 817 630, fax 217 931 095 e com o endereço de correio eletrónico revista@spc.pt. Declaro para todos os fins, que assumo inteira responsabilidade pela veracidade e exatidão da afirmação aqui fornecida.