que se leu este artigo
array:25 [ "pii" => "S0870255115002978" "issn" => "08702551" "doi" => "10.1016/j.repc.2015.05.008" "estado" => "S300" "fechaPublicacion" => "2015-12-01" "aid" => "727" "copyright" => "Sociedade Portuguesa de Cardiologia" "copyrightAnyo" => "2015" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "Rev Port Cardiol. 2015;34:779.e1-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4289 "formatos" => array:3 [ "EPUB" => 196 "HTML" => 3447 "PDF" => 646 ] ] "Traduccion" => array:1 [ "en" => array:19 [ "pii" => "S2174204915002858" "issn" => "21742049" "doi" => "10.1016/j.repce.2015.12.008" "estado" => "S300" "fechaPublicacion" => "2015-12-01" "aid" => "727" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "Rev Port Cardiol. 2015;34:779.e1-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2429 "formatos" => array:3 [ "EPUB" => 157 "HTML" => 1785 "PDF" => 487 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>" "titulo" => "Bioresorbable vascular scaffold for very late stent thrombosis resulting from ruptured neoatherosclerosisBioresorbable vascular scaffold for very late stent thrombosis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "pt" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "779.e1" "paginaFinal" => "779.e4" ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Plataformas biorreabsorbíveis no tratamento da trombose de <span class="elsevierStyleItalic">stent</span> muito tardia resultante de rotura de neoaterosclerose" ] ] "contieneResumen" => array:2 [ "en" => true "pt" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1224 "Ancho" => 1801 "Tamanyo" => 343730 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">(A) Coronary angiography in cranial view showing the occluded left anterior descending coronary artery (arrow); (B) final angiographic result after bioresorbable vascular scaffold deployment; (C) optical coherence tomography (OCT) image after thrombus aspiration showing heterogeneous intrastent tissue with large lipid pools (+). Some stent struts are poorly detected due to attenuation. There is also calcified tissue (Ca) surrounding some struts. Note plaque rupture (arrow); (D) OCT image after thrombus aspiration showing residual red thrombus (T) in an area with complete neointimal coverage. (*) denotes wire artifact; (E) 3D reconstruction of OCT image after thrombus aspiration with severe stenosis due to intrastent tissue (c) and residual red thrombus (T) (d).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Teresa Bastante, Fernando Rivero, Javier Cuesta, M. Cruz Aguilera, Daniel Rodríguez, Amparo Benedicto, Fernando Alfonso" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Teresa" "apellidos" => "Bastante" ] 1 => array:2 [ "nombre" => "Fernando" "apellidos" => "Rivero" ] 2 => array:2 [ "nombre" => "Javier" "apellidos" => "Cuesta" ] 3 => array:2 [ "nombre" => "M. 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Cruz Aguilera, Daniel Rodríguez, Amparo Benedicto, Fernando Alfonso" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Teresa" "apellidos" => "Bastante" ] 1 => array:2 [ "nombre" => "Fernando" "apellidos" => "Rivero" ] 2 => array:2 [ "nombre" => "Javier" "apellidos" => "Cuesta" ] 3 => array:2 [ "nombre" => "M. Cruz" "apellidos" => "Aguilera" ] 4 => array:2 [ "nombre" => "Daniel" "apellidos" => "Rodríguez" ] 5 => array:2 [ "nombre" => "Amparo" "apellidos" => "Benedicto" ] 6 => array:4 [ "nombre" => "Fernando" "apellidos" => "Alfonso" "email" => array:1 [ 0 => "falf@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Cardiac Department, Hospital Universitario de La Princesa, Madrid, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Plataformas biorreabsorbíveis no tratamento da trombose de <span class="elsevierStyleItalic">stent</span> muito tardia resultante de rotura de neoaterosclerose" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2038 "Ancho" => 3000 "Tamanyo" => 516958 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">(A) Coronary angiography in cranial view showing the occluded left anterior descending coronary artery (arrow); (B) final angiographic result after bioresorbable vascular scaffold deployment; (C) optical coherence tomography (OCT) image after thrombus aspiration showing heterogeneous intrastent tissue with large lipid pools (+). Some stent struts are poorly detected due to attenuation. There is also calcified tissue (Ca) surrounding some struts. Note plaque rupture (arrow); (D) OCT image after thrombus aspiration showing residual red thrombus (T) in an area with complete neointimal coverage. (*) denotes wire artifact; (E) 3D reconstruction of OCT image after thrombus aspiration with severe stenosis due to intrastent tissue (c) and residual red thrombus (T) (d).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Case report</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 52-year-old man with hyperlipidemia was admitted for an episode of prolonged chest pain. The electrocardiogram showed anterior ST-segment elevation from V1 to V3. Eight years before he had suffered an anterior myocardial infarction and a paclitaxel-eluting stent was implanted in the proximal left anterior descending coronary artery. Since then, the patient had been on aspirin and atorvastatin with adequate lipid control. Emergent coronary angiography revealed a complete occlusion (100<span class="elsevierStyleHsp" style=""></span>%, TIMI 0) of the most proximal segment of the stent (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>A). Thromboaspiration was successful in retrieving some red thrombus and in obtaining TIMI 3 coronary flow. Optical coherence tomography (OCT) (St. Jude Medical, St. Paul, MN, USA) disclosed complicated in-stent neoatherosclerosis characterized by a large and heterogeneous intrastent plaque with a large lipid pool. Near the area showing the minimal lumen diameter a ruptured fibrous cap associated with white and red thrombi was identified (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>C). In some segments the stent struts could hardly be visualized as the result of significant shadowing caused by the red thrombus or the attenuation induced by lipid plaque. In addition, relatively large, residual red thrombi were also detected in other segments of the stent (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>D and E). The rest of the stent was well covered by homogeneous and bright neointima. There was moderate stent underexpansion but no evidence of uncovered struts or malapposition was detected along the stent. Multiple high-pressure dilatations were performed with a 3 mm non-compliant balloon, with clear lumen improvement but still with a suboptimal angiographic result (intrastent haziness with residual stenosis). A 3.0 mm bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, CA, USA) was implanted and subsequently postdilated with a 3.25 mm non-compliant balloon at 20 bar, with an excellent final angiographic result (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>B). Repeat OCT disclosed a properly apposed and expanded device. The characteristic image of the BVS struts (box-like appearance without dorsal shadowing) was clearly identified against the underlying residual neointimal or atherosclerotic tissue over the underlying metallic stent (bright struts with clear-cut posterior shadow) (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>A). There was a moderate rise in cardiac enzymes (peak high-sensitive troponin T 1115 ng/l, peak creatinine kinase 309 U/l) but the clinical course was uneventful and the patient was discharged on aspirin and prasugrel three days later. Unfortunately, three months later the patient himself decided to stop dual antiplatelet therapy. After four days without medication, he suffered a new anterior myocardial infarction. Emergent coronary angiography revealed a thrombosis of the BVS, which was successfully treated with thromboaspiration and dilatation with a non-compliant balloon (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>B). Six months later the patient remains asymptomatic with good adherence to treatment. A scheduled coronary angiography at this time confirmed an excellent result in the target segment. OCT showed a well expanded and apposed BVS with complete neointimal coverage (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>C and D).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Discussion</span><p id="par0010" class="elsevierStylePara elsevierViewall">Very late stent thrombosis is a rare but devastating complication after percutaneous coronary revascularization. Stent thrombosis may be due to a mechanical problem such as stent malapposition or underexpansion. On the other hand, pathological studies have demonstrated that neoatherosclerosis plays a major role in certain patients with very late stent thrombosis.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a> Interestingly, neoatherosclerosis occurs not only more frequently but also earlier in patients treated with drug-eluting stents compared with those treated with bare-metal stents.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a> When the thrombosis is related to stent malapposition or underexpansion, balloon angioplasty without stent deployment is sufficient in most cases. However, the therapy of choice for patients presenting with very late in-stent restenosis or very late stent thrombosis as a result of neoatherosclerosis remains unclear.<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">2,3</span></a> In this context the use of BVS is a potentially attractive strategy to avoid the implantation of an additional metal layer while ensuring an optimal acute result and benefiting from their unique antirestenotic efficacy; in addition, they may promote plaque stability and passivation of vulnerable plaques by providing a uniform homogeneous neointimal layer.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">4</span></a> In this regard, some preliminary reports have suggested the value of BVS in patients with in-stent restenosis.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">5</span></a> However, the use of BVS in patients with very late stent thrombosis has not been previously reported. Currently, neoatherosclerosis may be readily recognized using OCT at a resolution of 15 μm.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">3</span></a> This technique is able to unravel the underlying pathological substrate in patients presenting with stent failure. The unique insights provided by OCT may help to tackle underlying mechanical problems such as stent malapposition or underexpansion and neoatherosclerosis, and also to optimize BVS deployment.<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">6,7</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Our findings suggest the value of BVS for the treatment of selected patients suffering from very late stent thrombosis as a result of neoatherosclerosis. However, only prospective studies will be able to establish the potential role of this novel form of therapy in this challenging anatomic scenario. In addition, the subsequent episode of BVS thrombosis, which in our case was closely related to lack of adherence to prescribed medications, reminds us of the important role of patient education and counseling to ensure the maintenance of appropriate dual antiplatelet therapy.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Ethical disclosures</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Protection of human and animal subjects</span><p id="par0020" class="elsevierStylePara elsevierViewall">The authors declare that the procedures followed were in accordance with the regulations of the relevant clinical research ethics committee and with those of the Code of Ethics of the World Medical Association (Declaration of Helsinki).</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Confidentiality of data</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data.</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Right to privacy and informed consent</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article. The corresponding author is in possession of this document.</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Conflicts of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:9 [ 0 => array:3 [ "identificador" => "xres591252" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0005" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec606832" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres591251" "titulo" => "Resumo" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0010" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec606831" "titulo" => "Palavras-chave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Case report" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Discussion" ] 6 => array:3 [ "identificador" => "sec0015" "titulo" => "Ethical disclosures" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0020" "titulo" => "Protection of human and animal subjects" ] 1 => array:2 [ "identificador" => "sec0025" "titulo" => "Confidentiality of data" ] 2 => array:2 [ "identificador" => "sec0030" "titulo" => "Right to privacy and informed consent" ] ] ] 7 => array:2 [ "identificador" => "sec0035" "titulo" => "Conflicts of interest" ] 8 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2015-03-10" "fechaAceptado" => "2015-06-12" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec606832" "palabras" => array:4 [ 0 => "Optical coherence tomography" 1 => "Bioresorbable vascular scaffolds" 2 => "Stent thrombosis" 3 => "Neoatherosclerosis" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec606831" "palabras" => array:4 [ 0 => "Tomografia de coerência ótica" 1 => "Suportes vasculares biorreabsorbíveis" 2 => "Trombose de <span class="elsevierStyleItalic">stent</span>" 3 => "Neoateroasclerose" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Very late stent thrombosis is a rare but devastating complication after percutaneous coronary revascularization. Pathological studies have demonstrated that neoatherosclerosis plays a major role in certain patients with very late stent thrombosis. Optical coherence tomography is able to unravel the underlying pathophysiology and may be used to select the best treatment option. This case report describes the use of a bioresorbable vascular scaffold (BVS) in a patient suffering from very late stent thrombosis due to a complicated plaque in the setting of intrastent neoatherosclerosis. To our knowledge, this therapeutic strategy has not been previously reported in patients suffering from very late stent thrombosis. In this scenario, BVS implantation might represent an attractive strategy in selected patients.</p></span>" ] "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A trombose de <span class="elsevierStyleItalic">stent</span> muito tardia é uma complicação rara mas preocupante após a revascularização coronária percutânea. Estudos patológicos têm demonstrado que a neoaterosclerose desempenha um papel importante em doentes selecionados com trombose de <span class="elsevierStyleItalic">stent</span> muito tardia. A tomografia de coerência ótica contribui para a compreensão da fisiopatologia subjacente, permitindo selecionar a melhor opção de tratamento. No presente caso descrevemos a utilização de um <span class="elsevierStyleItalic">stent</span> vascular bioabsorvível num doente que apresentava trombose de <span class="elsevierStyleItalic">stent</span> muito tardia devido a placa complexa no contexto de neoaterosclerose intrastent. De acordo com a nossa experiência, esta estratégia terapêutica não tem sido apresentada em doentes com trombose de <span class="elsevierStyleItalic">stent</span> muito avançada. Neste cenário, a implantação de suportes vasculares bioabsorbíveis pode representar uma estratégia atrativa em doentes selecionados.</p></span>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2038 "Ancho" => 3000 "Tamanyo" => 516958 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">(A) Coronary angiography in cranial view showing the occluded left anterior descending coronary artery (arrow); (B) final angiographic result after bioresorbable vascular scaffold deployment; (C) optical coherence tomography (OCT) image after thrombus aspiration showing heterogeneous intrastent tissue with large lipid pools (+). Some stent struts are poorly detected due to attenuation. There is also calcified tissue (Ca) surrounding some struts. Note plaque rupture (arrow); (D) OCT image after thrombus aspiration showing residual red thrombus (T) in an area with complete neointimal coverage. (*) denotes wire artifact; (E) 3D reconstruction of OCT image after thrombus aspiration with severe stenosis due to intrastent tissue (c) and residual red thrombus (T) (d).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2271 "Ancho" => 2500 "Tamanyo" => 612343 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">(A) Optical coherence tomography (OCT) findings after bioresorbable vascular scaffold (BVS) implantation. The device was fully expanded and apposed. The metallic struts of the underlying stent are clearly detected (posterior shadow) in the far field; (B) OCT findings during BVS thrombosis, with large platelet-rich thrombus (pT) occupying the lumen and the characteristic box-like appearance of the BVS struts; (C) OCT after six months. Notice complete neointimal coverage of struts. (*) denotes wire artifact; (D) 3D reconstruction of OCT image after six months.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0040" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The pathology of neoatherosclerosis in human coronary implants bare-metal and drug-eluting stents" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "G. Nakazawa" 1 => "F. Otsuka" 2 => "M. Nakano" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2011.01.011" "Revista" => array:7 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2011" "volumen" => "57" "numero" => "11" "paginaInicial" => "1314" "paginaFinal" => "1322" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21376502" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0045" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "In-stent restenosis in the drug-eluting stent era" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "G.D. Dangas" 1 => "B.E. Claessen" 2 => "A. Caixeta" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2010.07.028" "Revista" => array:7 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2010" "volumen" => "56" "numero" => "23" "paginaInicial" => "1897" "paginaFinal" => "1907" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21109112" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0050" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Current treatment of in-stent restenosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "F. Alfonso" 1 => "R.A. Byrne" 2 => "F. Rivero" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2014.02.545" "Revista" => array:7 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2014" "volumen" => "63" "numero" => "24" "paginaInicial" => "2659" "paginaFinal" => "2673" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24632282" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0055" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Circumferential evaluation of the neointima by optical coherence tomography after ABSORB bioresorbable vascular scaffold implantation: can the scaffold cap the plaque" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "S. Brugaletta" 1 => "M.D. Radu" 2 => "H.M. Garcia-Garcia" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.atherosclerosis.2011.12.008" "Revista" => array:6 [ "tituloSerie" => "Atherosclerosis" "fecha" => "2012" "volumen" => "221" "paginaInicial" => "106" "paginaFinal" => "112" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22209268" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0060" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of coronary in-stent restenosis with bioabsorbable vascular scaffolds" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "F. Alfonso" 1 => "J. Nuccio" 2 => "C. Cuevas" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2013.05.107" "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2014" "volumen" => "63" "numero" => "25 Pt A" "paginaInicial" => "2875" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24969756" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0065" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "First serial assessment at 6 months and 2 years of the second generation of absorb everolimus-eluting bioresorbable vascular scaffold: a multi-imaging modality study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "J.A. Ormiston" 1 => "P.W. Serruys" 2 => "Y. Onuma" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/CIRCINTERVENTIONS.112.971549" "Revista" => array:7 [ "tituloSerie" => "Circ Cardiovasc Interv" "fecha" => "2012" "volumen" => "5" "numero" => "5" "paginaInicial" => "620" "paginaFinal" => "632" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23048057" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0070" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of in-stent restenosis with bioresorbable vascular scaffolds: optical coherence tomography insights" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "F. Rivero" 1 => "T. Bastante" 2 => "J. Cuesta" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.cjca.2014.11.017" "Revista" => array:6 [ "tituloSerie" => "Can J Cardiol" "fecha" => "2015" "volumen" => "31" "paginaInicial" => "255" "paginaFinal" => "259" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25660152" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/08702551/0000003400000012/v1_201512210110/S0870255115002978/v1_201512210110/en/main.assets" "Apartado" => array:4 [ "identificador" => "362" "tipo" => "SECCION" "pt" => array:2 [ "titulo" => "Casos clínicos" "idiomaDefecto" => true ] "idiomaDefecto" => "pt" ] "PDF" => "https://static.elsevier.es/multimedia/08702551/0000003400000012/v1_201512210110/S0870255115002978/v1_201512210110/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115002978?idApp=UINPBA00004E" ]
Ano/Mês | Html | Total | |
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2023 Setembro | 22 | 21 | 43 |
2023 Agosto | 36 | 16 | 52 |
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2022 Outubro | 35 | 18 | 53 |
2022 Setembro | 35 | 32 | 67 |
2022 Agosto | 33 | 39 | 72 |
2022 Julho | 40 | 41 | 81 |
2022 Junho | 27 | 26 | 53 |
2022 Maio | 28 | 34 | 62 |
2022 Abril | 44 | 34 | 78 |
2022 Maro | 32 | 37 | 69 |
2022 Fevereiro | 27 | 27 | 54 |
2022 Janeiro | 22 | 28 | 50 |
2021 Dezembro | 23 | 42 | 65 |
2021 Novembro | 43 | 38 | 81 |
2021 Outubro | 47 | 41 | 88 |
2021 Setembro | 31 | 29 | 60 |
2021 Agosto | 39 | 33 | 72 |
2021 Julho | 23 | 17 | 40 |
2021 Junho | 23 | 32 | 55 |
2021 Maio | 36 | 37 | 73 |
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2020 Dezembro | 41 | 14 | 55 |
2020 Novembro | 38 | 23 | 61 |
2020 Outubro | 21 | 12 | 33 |
2020 Setembro | 60 | 19 | 79 |
2020 Agosto | 20 | 8 | 28 |
2020 Julho | 41 | 13 | 54 |
2020 Junho | 32 | 12 | 44 |
2020 Maio | 41 | 7 | 48 |
2020 Abril | 49 | 22 | 71 |
2020 Maro | 50 | 7 | 57 |
2020 Fevereiro | 65 | 15 | 80 |
2020 Janeiro | 36 | 14 | 50 |
2019 Dezembro | 35 | 17 | 52 |
2019 Novembro | 50 | 9 | 59 |
2019 Outubro | 39 | 6 | 45 |
2019 Setembro | 33 | 8 | 41 |
2019 Agosto | 38 | 6 | 44 |
2019 Julho | 54 | 8 | 62 |
2019 Junho | 45 | 23 | 68 |
2019 Maio | 61 | 7 | 68 |
2019 Abril | 36 | 16 | 52 |
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2018 Outubro | 247 | 37 | 284 |
2018 Setembro | 85 | 14 | 99 |
2018 Agosto | 45 | 16 | 61 |
2018 Julho | 48 | 9 | 57 |
2018 Junho | 75 | 4 | 79 |
2018 Maio | 87 | 7 | 94 |
2018 Abril | 88 | 3 | 91 |
2018 Maro | 103 | 6 | 109 |
2018 Fevereiro | 65 | 10 | 75 |
2018 Janeiro | 71 | 4 | 75 |
2017 Dezembro | 105 | 8 | 113 |
2017 Novembro | 51 | 9 | 60 |
2017 Outubro | 44 | 16 | 60 |
2017 Setembro | 93 | 7 | 100 |
2017 Agosto | 84 | 10 | 94 |
2017 Julho | 58 | 7 | 65 |
2017 Junho | 54 | 11 | 65 |
2017 Maio | 134 | 7 | 141 |
2017 Abril | 52 | 4 | 56 |
2017 Maro | 62 | 50 | 112 |
2017 Fevereiro | 115 | 9 | 124 |
2017 Janeiro | 60 | 3 | 63 |
2016 Dezembro | 37 | 13 | 50 |
2016 Novembro | 44 | 11 | 55 |
2016 Outubro | 58 | 7 | 65 |
2016 Setembro | 91 | 7 | 98 |
2016 Agosto | 47 | 4 | 51 |
2016 Julho | 12 | 7 | 19 |
2016 Junho | 4 | 6 | 10 |
2016 Maio | 12 | 10 | 22 |
2016 Abril | 35 | 2 | 37 |
2016 Maro | 50 | 12 | 62 |
2016 Fevereiro | 59 | 24 | 83 |
2016 Janeiro | 88 | 62 | 150 |
2015 Dezembro | 73 | 51 | 124 |