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also with a thrombus inside&#46; The patient underwent corrective surgery with a Dor procedure &#40;endoventricular circular patch plasty&#41; combined with VSD closure and resection of the RV pseudoaneurysm &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Figure 4</a>&#41;&#46; The procedure was successful and the postoperative course was uneventful&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Discussion</span><p id="par0015" class="elsevierStylePara elsevierViewall">Postinfarction VSD is usually associated with multivessel coronary artery disease with significant stenosis in all major vessels&#46; In the case reported&#44; although the angiographic pattern was completely normal&#44; STEMI was complicated by a VSD&#44; LV aneurysm and RV pseudoaneurysm&#46; VSD usually occurs in the first two weeks after infarction&#44; with a peak in the first 24 hours and between the third and fifth day post-infarction&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#8211;3</span></a> It is associated with signs of pulmonary congestion&#44; biventricular failure&#44; and hypotension&#44; which were not observed in our patient during that period&#46; Clinical features associated with an increased risk of VSD include lack of development of a collateral network&#44; advanced age&#44; hypertension&#44; anterior wall infarction and possibly fibrinolysis&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> Medical treatment is usually not effective and early surgical closure of the rupture is recommended&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> The pathophysiology&#44; clinical characteristics&#44; and prognosis of STEMI with angiographically normal coronary arteries are still under investigation&#46; Smoking&#44; cocaine abuse&#44; hypercoagulable states&#44; myocardial bridging&#44; trauma&#44; endothelial dysfunction and vasospasm&#44; together with acute myocarditis&#44; are among the most frequently reported causes&#44; but none were present in this patient&#46; Nevertheless&#44; the apparently normal coronary arteriogram could be explained by disruption with thrombosis of a plaque at a site of outward remodeling of the artery followed by spontaneous lysis or distal embolization of the thrombus into the microcirculation after fragmentation&#46; The compensatory enlargement or positive remodeling maintained the lumen caliber of the coronary artery affected by atherosclerosis&#44; explaining the normal angiographic pattern&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">STEMI with angiographically normal coronary arteries appears to be less severe&#44; with fewer complications during the acute and late phases compared with infarction due to severe atherosclerotic disease&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> Although its incidence has decreased considerably since the advent of early mechanical reperfusion&#44; STEMI complications are associated with a high rate of mortality and urgent need for early surgical repair&#46; This case report discusses the unusual presentation of STEMI with normal coronary arteries and severe mechanical complications successfully treated with surgery&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Ethical disclosures</span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Protection of human and animal subjects</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare that the procedures followed were in accordance with the regulations of the relevant clinical research ethics committee and with those of the Code of Ethics of the World Medical Association &#40;Declaration of Helsinki&#41;&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Confidentiality of data</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Right to privacy and informed consent</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conflicts of interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
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Case report
Multiple mechanical complications in ST-segment elevation myocardial infarction with angiographically normal coronary arteries
Enfarte agudo do miocárdio com supradesnivelamento de ST com múltiplas complicações mecânicas e artérias coronárias angiograficamente normais
André Viveiros Monteiroa,
Autor para correspondência
andreviveirosmonteiro@gmail.com

Corresponding author.
, Ana Galrinhoa, Luísa Moura Brancoa, José Fragatab, Rui Cruz Ferreiraa
a Cardiology Department, Hospital of Santa Marta, Lisbon, Portugal
b Cardiothoracic Surgery Department, Hospital of Santa Marta, Lisbon, Portugal
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also with a thrombus inside&#46; The patient underwent corrective surgery with a Dor procedure &#40;endoventricular circular patch plasty&#41; combined with VSD closure and resection of the RV pseudoaneurysm &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Figure 4</a>&#41;&#46; The procedure was successful and the postoperative course was uneventful&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Discussion</span><p id="par0015" class="elsevierStylePara elsevierViewall">Postinfarction VSD is usually associated with multivessel coronary artery disease with significant stenosis in all major vessels&#46; In the case reported&#44; although the angiographic pattern was completely normal&#44; 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clinical characteristics&#44; and prognosis of STEMI with angiographically normal coronary arteries are still under investigation&#46; Smoking&#44; cocaine abuse&#44; hypercoagulable states&#44; myocardial bridging&#44; trauma&#44; endothelial dysfunction and vasospasm&#44; together with acute myocarditis&#44; are among the most frequently reported causes&#44; but none were present in this patient&#46; Nevertheless&#44; the apparently normal coronary arteriogram could be explained by disruption with thrombosis of a plaque at a site of outward remodeling of the artery followed by spontaneous lysis or distal embolization of the thrombus into the microcirculation after fragmentation&#46; The compensatory enlargement or positive remodeling maintained the lumen caliber of the coronary artery affected by atherosclerosis&#44; explaining the normal angiographic pattern&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">STEMI with angiographically normal coronary arteries appears to be less severe&#44; with fewer complications during the acute and late phases compared with infarction due to severe atherosclerotic disease&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> Although its incidence has decreased considerably since the advent of early mechanical reperfusion&#44; STEMI complications are associated with a high rate of mortality and urgent need for early surgical repair&#46; This case report discusses the unusual presentation of STEMI with normal coronary arteries and severe mechanical complications successfully treated with surgery&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Ethical disclosures</span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Protection of human and animal subjects</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare that the procedures followed were in accordance with the regulations of the relevant clinical research ethics committee and with those of the Code of Ethics of the World Medical Association &#40;Declaration of Helsinki&#41;&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Confidentiality of data</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Right to privacy and informed consent</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conflicts of interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">O presente caso cl&#237;nico discute a apresenta&#231;&#227;o incomum de um enfarte agudo do mioc&#225;rdio com supradesnivelamento de ST &#40;EAMCST&#41; com complica&#231;&#245;es mec&#226;nicas graves e art&#233;rias coron&#225;rias normais tratado cirurgicamente com sucesso&#46; Um homem de 82 anos sofreu um EAMCST com art&#233;rias coron&#225;rias angiograficamente normais e sem altera&#231;&#245;es ecocardiogr&#225;ficas de relevo aquando da alta&#46; Na consulta do primeiro m&#234;s p&#243;s enfarte&#44; por queixas de cansa&#231;o e dispneia&#44; realizou um ecocardiograma complementado por uma resson&#226;ncia magn&#233;tica card&#237;aca que revelaram um grande aneurisma apical do ventr&#237;culo esquerdo&#44; com trombo&#44; comunicando atrav&#233;s de dois jatos de fluxo turbulento com uma forma&#231;&#227;o aneurism&#225;tica do &#225;pice do ventr&#237;culo direito&#46; O paciente foi submetido a um procedimento de Dor com sucesso&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A rutura do septo interventricular e os aneurismas ventriculares permanecem eventos raros mas devastadores com a quase maioria dos pacientes apresentado doen&#231;a coron&#225;ria multivaso&#46; Curiosamente neste caso&#44; o padr&#227;o angiogr&#225;fico era normal&#46;</p></span>"
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ISSN: 08702551
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2020 Dezembro 21 15 36
2020 Novembro 41 8 49
2020 Outubro 8 8 16
2020 Setembro 51 16 67
2020 Agosto 20 5 25
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