Journal Information
Vol. 30. Issue 9.
Pages 717-726 (September 2011)
Vol. 30. Issue 9.
Pages 717-726 (September 2011)
Open Access
Tomografia computorizada multicorte na avaliação de candidatos a implantação de prótese aórtica percutânea
Multislice computed tomography in the selection of candidates for transcatheter aortic valve implantation
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Gustavo Pires de Morais
Corresponding author
gpmorais@gmail.com

Autor para correspondência.
, Nuno Bettencourt, Guida Silva, Nuno Ferreira, Olga Sousa, Daniel Caeiro, João Rocha, Mónica Carvalho, Daniel Leite, Pedro Braga, Conceição Fonseca, Vasco Gama
Serviço de Cardiologia, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal
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Resumo

A substituição valvular aórtica percutânea é uma opção emergente para o tratamento da estenose aórtica grave sintomática em doentes recusados para substituição valvular cirúrgica. Os autores fazem uma revisão da literatura na utilização da Tomografia Computorizada Multicorte na avaliação de candidatos a implantação de prótese aórtica percutânea, no apoio ao procedimento e seguimento pós-intervenção. Os autores descrevem, ainda, a experiência de um Centro na utilização desta técnica de imagem no contexto de substituição valvular aórtica percutânea.

A Tomografia Computorizada Multicorte é um método de imagem de eleição na selecção e exclusão de candidatos a implantação valvular aórtica percutânea, permitindo avaliação da anatomia coronária e relação dos ostia coronários com a estrutura valvular aórtica, avaliação precisa do anel valvular e restante raiz aórtica, câmara de saída do ventrículo esquerdo, aorta e acessos vasculares periféricos. As imagens obtidas por Tomografia Computorizada Multicorte são informação central na escolha da dimensão da prótese a implantar, permitem apoio à punção vascular durante o procedimento por métodos de fusão de imagem e efectuar seguimento à adequada aposição da prótese.

Palavras-chave:
Estenose aórtica grave
Substituição valvular aórtica percutânea
Tomografia Computorizada Multicorte
Abstract

Transcatheter aortic valve implantation is an emerging treatment option for severe symptomatic aortic stenosis in patients considered unsuitable for surgical valve replacement. The authors review the use of multislice computed tomography in the selection of candidates for transcatheter aortic valve replacement, procedural support and post-interventional follow-up. A single-center experience of the role of this imaging technique is also described.

Multislice computed tomography is an essential imaging tool in the selection and exclusion of candidates for transcatheter aortic valve implantation, providing evaluation of coronary anatomy and the relationship of the coronary ostia with the aortic valve structure, and accurate analysis of the valve annulus and aortic root, left ventricular outflow tract, aorta and peripheral vascular access routes. Multislice computed tomography is also central to the choice of appropriate prosthesis size. In addition, it guides arterial puncture by image fusion techniques and enables correct prosthesis apposition to be verified. This review aims to describe the role of computed tomography in this increasingly common interventional valve procedure, providing an overview of current knowledge and applications.

Keywords:
Severe aortic stenosis
Transcatheter aortic valve implantation
Multislice computed tomography
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Bibliografia
[1.]
A. Vahanian, H. Baumgartner, J. Bax, et al.
Guidelines on the management of valvular heart disease.
Eur Heart J, 28 (2007), pp. 230-268
[2.]
J. Ross Jr., E. Braunwald.
Aortic stenosis.
Circulation, 38 (1968), pp. 61-67
[3.]
J. Turina, O. Hess, F. Sepulcri, et al.
Spontaneous course of aortic valve disease.
Eur Heart J, 8 (1987), pp. 471-483
[4.]
M.B. Leon, C.R. Smith, M. Mack, et al.
Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery.
N Engl J Med, 363 (2010), pp. 1597-1607
[5.]
B. Iung, G. Baron, E.G. Butchart, et al.
A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on valvular disease.
Eur Heart J, 24 (2003), pp. 1231-1243
[6.]
B. Iung.
Decision-making in elderly patients with severe aortic stenosis: Why are so many denied surgery?.
Eur Heart J, 26 (2005), pp. 2714-2720
[7.]
A. Chukwuemeka, M.A. Borger, J. Ivanov, et al.
Valve surgery in octogenarians: a safe option with good medium-term results.
J Heart Valve Dis, 15 (2006), pp. 191-196
[8.]
S.J. Melby, A. Zierer, Y.P. Kaiser, et al.
Aortic valve replacement in octogenarians Risk factors for early and late mortality.
Ann Thorac Surg, 83 (2007), pp. 1651-1657
[9.]
W.C. Roberts, J.M. Ko, W.L. Garner, et al.
Valve structure and survival in octogenarians having aortic valve replacement for aortic stenosis (± aortic regurgitation) with versus without coronary artery bypass grafting at a single US medical center (1993–2005).
Am J Cardiol, 100 (2007), pp. 489-495
[10.]
P. Kolh, A. Kerzmann, C. Honore, et al.
Aortic valve surgery in octogenarians: predictive factors for operative and long-term results.
Eur J Cardiothorac Surg, 31 (2007), pp. 600-606
[11.]
E. Charlson, A.T. Legedza, M.B. Hamel.
Decision-making and outcomes in severe symptomatic aortic stenosis.
J Heart Valve Dis, 15 (2006), pp. 312-321
[12.]
A. Cribier, H. Eltchaninoff, A. Bash, et al.
Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description.
Circulation, 106 (2002), pp. 3006-3008
[13.]
E. Grube, L. Buellesfeld, R. Mueller, et al.
Progress and current status of percutaneous aortic valve replacement: results of three device generations of the corevalve revalving system.
Circ Cardiovasc Interv, 1 (2008), pp. 167-175
[14.]
J.B. Masson, J. Kovac, G. Schuler, et al.
Transcatheter aortic valve implantation Review of the nature, management, and avoidance of procedural complications.
JACC Cardiovasc Interv, 2 (2009), pp. 811-820
[15.]
L.F. Tops, V. Delgado, F. Van der Kley, et al.
Percutaneous aortic valve therapy: clinical experience and the role of multi-modality imaging.
Heart, 95 (2009), pp. 1538-1546
[16.]
A. Vahanian, O. Alfieri, N. Al-Attar, et al.
Transcatheter valve implantation for patients with aortic stenosis: a position statement from the European association of cardio-thoracic surgery (EACTS) and the European Society of Cardiology (ESC), in collabo*ration with the European Association of Percutaneous Cardiovascular Interventions (EAPCI).
Eur Heart J, 29 (2008), pp. 1463-1470
[17.]
T.M. Dewey, D. Brown, W.H. Ryan, et al.
Reliability of risk algorithms in predicting early and late operative outcomes in high risk patients undergoing aortic valve replacement.
J Thorac Cardiovasc Surg, 135 (2008), pp. 180-187
[18.]
J. Hur, Y.J. Kim, H.J. Lee, et al.
Left atrial appendage thrombi in stroke patients: detection with two-phase cardiac CT angiography versus transesophageal echocardiography.
Radiology, 251 (2009), pp. 683-690
[19.]
M.D. Shapiro, T.G. Neilan, D.S. Jassal, et al.
Multidetector computed tomography for the detection of left atrial appendage thrombus: a comparative study with transesophageal echocardiography.
J Comput Assist Tomogr, 31 (2007), pp. 905-909
[20.]
H. Tomoda, M. Hoshiai, H. Furuya, et al.
Evaluation of intracardiac thrombus with computed tomography.
Am J Cardiol, 51 (1983), pp. 843-852
[21.]
R. Nakazato, B.K. Tamarappoo, T.W. Smith, et al.
Assessment of left ventricular regional wall motion and ejection fraction with low-radiation dose helical dual-source CT: Comparison to two-dimensional echocardiography.
J Cardiovasc Comput Tomogr, 5 (2011), pp. 149-157
[22.]
N. Bettencourt, J. Rocha, M. Carvalho, et al.
Multislice computed tomography in the exclusion of coronary artery disease in pre surgical valve disease patients.
Circ Cardiovasc Imaging, 2 (2009), pp. 279-281
[23.]
W.B. Meijboom, N.R. Mollet, C.A. Van Mieghem, et al.
Preoperative computed tomography coronary angiography to detect significant coronary artery disease in patients for cardiac valve surgery.
J Am Coll Cardiol, 48 (2006), pp. 1658-1665
[24.]
M. Gilard, J.C. Cornily, P.Y. Pennec, et al.
Accuracy of multislice computed tomography in the preoperative assessment of coronary disease in patients with aortic valve stenosis.
J Am Coll Cardiol, 47 (2006), pp. 2020-2024
[25.]
P. Reant, S. Brunot, S. Lafitte, et al.
Predictive value of noninvasive coronary angiography with multidetector computed tomography to detect significant coronary stenosis before valve surgery.
Am J Cardiol, 97 (2006), pp. 1506-1510
[26.]
N. Piazza, P.P. De Jaegere, C.J. Schultz, et al.
Anatomy of the aortic valve complex and its implications for transcathether implantation of the aortic valve.
Circ Cardiovasc Interv, 1 (2008), pp. 74-81
[27.]
C.J. Schultz, A.D. Moelker, A. Tzikas, et al.
Cardiac CT: necessary for precise sizing for transcathether aortic implantation.
Eurointervention, 6 (2010), pp. G6-G13
[28.]
C.J. Schultz, A.D. Moelker, N. Piazza, et al.
Three dimensional evaluation of the aortic annulus using multislice computer tomography: are manufacturer's guidelines for sizing the percutaneous aortic valve replacement helpful?.
Eur Heart J, 31 (2010), pp. 849-856
[29.]
P. Shoenhagen, U. Numburi, S.S. Halliburton, et al.
Threedimensional imaging in the context of minimally invasive and transcathether cardiovascular interventions using multi-detector computed tomography: from pre-operative planning to intra-operative guidance.
Eur Heart J, 31 (2010), pp. 2727-2740
[30.]
P. Schoenhagen, E. Morat Tuzcu, S.R. Kapadia, et al.
Threedimensional imaging of the aortic valve and aortic root with computed tomography: new standards in the era of transcathether valve repair/implantation.
Eur Heart J, 30 (2009), pp. 2079-2086
[31.]
D.A. Wood, L.F. Tops, J.R. Mayo, et al.
Role of multislice computed tomography in transcathether aortic valve replacement.
Am J Cardiol, 103 (2009), pp. 1295-1301
[32.]
A. Dashkevich, P. Blanke, M. Siepe, et al.
Preoperative assessment of aortic annulus dimensions: comparison of noninvasive and intraoperative measurement.
Ann Thorac Surg, 91 (2011), pp. 709-714
[33.]
A. Tzikas, C.J. Schultz, N. Piazza, et al.
Assessment of the aortic annulus by multi-slice computed tomography, contrast aortography and trans-thoracic echocardiography in patients referred for transcatheter aortic valve implantation.
Catheter Cardiovasc Interv, 77 (2011), pp. 868-875
[34.]
A. Hutter, A. Opitz, S. Bleiziffer, et al.
Aortic annulus evaluation in transcatheter aortic valve implantation.
Catheter Cardiovasc Interv, 76 (2010), pp. 1009-1019
[35.]
L.F. Tops, D.A. Wood, V. Delgado, et al.
Noninvasive evaluation of the aortic root with multislice computed tomography: implications for transcatheter aortic valve replacement.
JACC Cardiovasc Imaging, 1 (2008), pp. 321-330
[36.]
J.G. Webb, M. Chandavimol, C.R. Thomson, et al.
Percutaneous aortic valve implantation retrograde from the femoral artery.
Circulation, 113 (2006), pp. 842-850
[37.]
T. Walther, V. Falk, J. Kempfert, et al.
Transapical minimally invasive aortic valve implantation: the initial 50 patients.
Eur J Cardiothorac Surg, 33 (2008), pp. 983-988
[38.]
T. Pflederer, S. Achenbach.
Aortic valve stenosis: CT contributions to diagnosis and therapy.
J Cardiovasc Comp Tomog, 4 (2010), pp. 355-364
[39.]
H. Baumgartner, J. Hung, J. Bermejo, et al.
Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice.
Eur J Echocardiogr, 10 (2009), pp. 1-25
[40.]
G. De la Morena, D. Saura, M.J. Oliva, et al.
Real-time threedimensional transesophageal echocardiography in the assessment of aortic valve stenosis.
Eur J Echocardiogr, 11 (2010), pp. 9-13
[41.]
R.G. Shah, G.M. Novaro, R.J. Blandon, et al.
Aortic valve area: meta-analysis of diagnostic performance of multi-detector computed tomography for aortic valve area measurements as compared to transthoracic echocardiography.
Int J Cardiovasc Imaging, 25 (2009), pp. 601-609
[42.]
J. Abdulla, J. Sivertsen, K.F. Kofoed, et al.
Evaluation of aortic valve stenosis by cardiac multi-slice computed tomography compared with echocardiography: a systematic review and meta-analysis.
J Heart Valve Dis, 18 (2009), pp. 634-643
[43.]
E.J. Halpern, R. Mallya, M. Sewell, et al.
Differences in aortic valve area measured with CT planimetry and echocardiography (continuity equation) are related to divergent estimates of left ventricular outflow tract area.
AJR Am J Roentgenol, 192 (2009), pp. 1668-1673
[44.]
H. Utsunomiya, H. Yamamoto, J. Horiguchi, et al.
Underestimation of aortic valve area in calcified aortic valve disease: Effects of left ventricular outflow tract ellipticity.
[45.]
R. Zegdi, V. Ciobotaru, M. Noghin, et al.
Is it reasonable to treat all calcified stenotic aortic valves with a valved stent? Results from a human anatomic study in adults.
J Am Coll Cardiol, 51 (2008), pp. 579-584
[46.]
R. Rosenhek, T. Binder, G. Porenta, et al.
Predictors of outcome in severe, asymptomatic aortic stenosis.
N Engl J Med, 343 (2000), pp. 611-617
[47.]
K. Pohle, M. Otte, D. Ropers, et al.
Association of cardiovascular risk factors to aortic valve calcification as quantified by electron beam computed tomography.
Mayo Clin Proc, 79 (2004), pp. 1242-1246
[48.]
C.J. Schultz, A. Weustink, N. Piazza, et al.
Geometry and degree of apposition of the CoreValve revalving system with multislice computed tomography after implantation in patients with aortic stenosis.
J Am Coll Cardiol, 54 (2009), pp. 911-918
[49.]
R. Duarte, N. Bettencourt, J.C. Costa, et al.
Coronary computed tomography angiography in a single cardiac cycle with a mean radiation dose of approximately 1 mSv: initial experience.
Rev Port Cardiol, 29 (2010), pp. 1667-1676
[50.]
P.J. Sousa, P.A. Gonçalves, H. Marques, et al.
Radiation in cardiac CT: predictors of higher dose and its reduction over time.
Rev Port Cardiol, 29 (2010), pp. 1655-1665
[51.]
D. Caeiro, R. Fontes-Carvalho, R. Lima, et al.
Implantação da válvula aórtica por via percutânea.
Rev Port Cardiol, 29 (2010), pp. 1699-1712
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