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"cabecera" => "<span class="elsevierStyleTextfn">Case report</span>" "titulo" => "Aortic embolization of an Edwards SAPIEN prosthesis due to sigmoid left ventricular hypertrophy: Case report" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "379.e1" "paginaFinal" => "379.e3" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Isa Öner Yuksel, Erkan Koklu, Sakir Arslan, Goksel Cagirci, Selcuk Kucukseymen" "autores" => array:5 [ 0 => array:4 [ "nombre" => "Isa Öner" "apellidos" => "Yuksel" "email" => array:1 [ 0 => "drisayuksel2@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Erkan" "apellidos" => "Koklu" ] 2 => array:2 [ "nombre" => "Sakir" "apellidos" => "Arslan" ] 3 => array:2 [ "nombre" => "Goksel" "apellidos" => "Cagirci" ] 4 => array:2 [ "nombre" => "Selcuk" "apellidos" => "Kucukseymen" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Cardiology Department, Antalya Education and Research Hospital, Antalya, Turkey" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Embolização aórtica da prótese Edwards Sapien devida a hipertrofia ventricular esquerda sigmóide: caso clínico" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 925 "Ancho" => 925 "Tamanyo" => 66361 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Fluoroscopic image of embolization of the Edwards SAPIEN prosthesis.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Transcatheter aortic valve implantation (TAVI) is emerging as an alternative to surgical aortic valve replacement for patients with symptomatic severe aortic stenosis considered to be at high or prohibitive operative risk.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> We report a case of embolization of an Edwards SAPIEN aortic valve due to sigmoid left ventricular hypertrophy, and discuss potential causes and solutions.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Case report</span><p id="par0010" class="elsevierStylePara elsevierViewall">A 75-year-old woman diagnosed with severe symptomatic aortic stenosis was referred for TAVI. The patient had a history of diabetes, hypertension, coronary artery disease, morbid obesity, and chronic renal failure. Transthoracic echocardiography (TTE) showed sigmoid left ventricular hypertrophy and ejection fraction of 60%, and Doppler echocardiography revealed a mean aortic gradient of 50 mmHg and an aortic valve area of 0.96 cm<span class="elsevierStyleSup">2</span> (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>). Transesophageal echocardiography (TEE) carried out for detailed examination revealed sigmoid left ventricular hypertrophy and an aortic annulus diameter of 24 mm. The aortic annulus diameter measured 26 mm×22 mm on multislice computed tomography. The patient was considered to be at too high risk for surgical aortic valve replacement and was referred for TAVI by a transfemoral approach.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">The process was performed under deep anesthesia and transthoracic echocardiographic guidance. The TAVI approach was through the right femoral artery using a 26 mm Edwards SAPIEN valve (Edwards Lifesciences, Inc., CA, USA). During balloon inflation under rapid pacing the valve prosthesis immediately embolized into the ascending aorta (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>). Attempts to position the valve in the descending aorta were unsuccessful and the bioprosthesis was re-expanded into the aortic arch between the brachiocephalic trunk and the left common carotid artery. At this stage a second Edwards SAPIEN valve was successfully implanted with gradual balloon inflation (<a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>). Arch aortography was carried out which showed no aortic regurgitation and no evidence of obstruction of the left common carotid artery or brachiocephalic trunk. The patient was transferred to the intensive care unit in a hemodynamically stable condition and was discharged one week after the procedure.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Discussion</span><p id="par0020" class="elsevierStylePara elsevierViewall">TAVI is a rapidly emerging treatment option for high-risk and inoperable patient groups. However, this new therapeutic modality raises new questions and problems that need to be identified and resolved. Although less invasive than open-chest aortic valve replacement, TAVI is associated with potentially serious complications, such as valve embolization. Valve embolization during TAVI is a life-threatening complication that requires immediate diagnosis and treatment.</p><p id="par0025" class="elsevierStylePara elsevierViewall">Procedural embolization of percutaneously implanted valves has been previously reported, with an incidence of 1.01%.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> Makkar et al. showed that patients with valve embolization had a greater body surface area and were more likely to be male. A cause for embolization was defined in post-procedural operator reports in 73% of cases. The most commonly stated causes were malpositioning, complex annulus/aortic valve anatomy, and pacing failure. Other causes included post-cardiopulmonary resuscitation, post-dilation, cardiac manipulation, displacement during attempted transcatheter valve-in-valve therapy, poor fluoroscopic angle for implantation, and incomplete/delayed device balloon inflation.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">In our case, distal embolization occurred due to sigmoid left ventricular hypertrophy, an example of complex annulus/aortic valve anatomy. In implantation of an aortic valve via a percutaneous route, the key factors for proper placement and fixation are choice of an appropriate size valve, accurate alignment and correct positioning. One of the most important limitations to the use of the Edwards SAPIEN valve system is sigmoid septum, which can lead to embolization of the prosthesis. In patients with pronounced sigmoid septum, apical placement of the Edwards SAPIEN valve or use of a Medtronic CoreValve are recommended.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> However, the presence of severe left ventricular hypertrophy and sigmoid septum are also an important predictor for permanent pacemaker requirement after the use of the CoreValve system. In this case, we preferred to use the Edwards SAPIEN valve because of lack of experience in apical placement and the Medtronic CoreValve system. Outcomes of distal aortic embolization of the Edwards SAPIEN valve remain good. The embolized prosthesis may be repositioned into the aortic arch without need for removal or surgery.<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">4,5</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Finally, the precise positioning of the valve, appropriate valve selection, and the route of administration of the procedure appear to be crucial for reducing the risk of valve migration.</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Ethical disclosures</span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Protection of human and animal subjects</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study.</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Confidentiality of data</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data.</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Right to privacy and informed consent</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appears in this article.</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conflicts of interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:10 [ 0 => array:3 [ "identificador" => "xres824772" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0005" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec821232" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres824771" "titulo" => "Resumo" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0010" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec821231" "titulo" => "Palavras chave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Case report" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Discussion" ] 7 => array:3 [ "identificador" => "sec0020" "titulo" => "Ethical disclosures" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0025" "titulo" => "Protection of human and animal subjects" ] 1 => array:2 [ "identificador" => "sec0030" "titulo" => "Confidentiality of data" ] 2 => array:2 [ "identificador" => "sec0035" "titulo" => "Right to privacy and informed consent" ] ] ] 8 => array:2 [ "identificador" => "sec0040" "titulo" => "Conflicts of interest" ] 9 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2015-06-26" "fechaAceptado" => "2015-09-13" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec821232" "palabras" => array:4 [ 0 => "Transcatheter aortic valve implantation" 1 => "Valve embolization" 2 => "Edwards SAPIEN" 3 => "Sigmoid left ventricular hypertrophy" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras chave" "identificador" => "xpalclavsec821231" "palabras" => array:4 [ 0 => "Implantação percutânea valvular aórtica" 1 => "Embolização valvular" 2 => "Edwards SAPIEN" 3 => "Hipertrofia ventricular esquerda sigmóide" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Transcatheter aortic valve implantation (TAVI) is considered an alternative therapy in high-risk patients with severe aortic stenosis. Although a minimally invasive procedure, it is not free from complications, one of which is valve embolization at the time of TAVI. We present a case of embolization of a balloon-expandable aortic valve due to sigmoid left ventricular hypertrophy and managed with a second valve without surgery. The embolized valve was repositioned in the aortic arch between the left common carotid artery and the brachiocephalic trunk.</p></span>" ] "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A implantação percutânea valvular aórtica (TAVI) é considerada uma terapêutica alternativa nos doentes de alto risco com estenose aórtica grave. Apesar de se tratar de um procedimento minimamente invasivo, o mesmo não está livre de complicações. Uma das quais é a embolização valvular no momento da TAVI. Apresentamos um caso de embolização valvular aórtica expansível por balão devido a hipertrofia ventricular esquerda sigmoide tratada com uma segunda válvula sem cirurgia. A válvula embolizada foi reposicionada na crossa da aorta entre a artéria carótida esquerda e o tronco braquiocefálico.</p></span>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 800 "Ancho" => 1027 "Tamanyo" => 112024 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Sigmoid left ventricular hypertrophy as observed on transthoracic echocardiography.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 925 "Ancho" => 925 "Tamanyo" => 66361 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Fluoroscopic image of embolization of the Edwards SAPIEN prosthesis.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 928 "Ancho" => 928 "Tamanyo" => 45097 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Fluoroscopy showing implantation of a second Edwards SAPIEN prosthesis and the embolized valve repositioned in the aortic arch.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0030" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "M.B. 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Year/Month | Html | Total | |
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2024 November | 4 | 5 | 9 |
2024 October | 34 | 28 | 62 |
2024 September | 53 | 33 | 86 |
2024 August | 61 | 31 | 92 |
2024 July | 42 | 27 | 69 |
2024 June | 36 | 21 | 57 |
2024 May | 52 | 34 | 86 |
2024 April | 30 | 23 | 53 |
2024 March | 51 | 23 | 74 |
2024 February | 52 | 36 | 88 |
2024 January | 50 | 33 | 83 |
2023 December | 29 | 38 | 67 |
2023 November | 48 | 18 | 66 |
2023 October | 41 | 16 | 57 |
2023 September | 41 | 26 | 67 |
2023 August | 34 | 20 | 54 |
2023 July | 48 | 5 | 53 |
2023 June | 28 | 11 | 39 |
2023 May | 55 | 25 | 80 |
2023 April | 33 | 7 | 40 |
2023 March | 39 | 25 | 64 |
2023 February | 36 | 17 | 53 |
2023 January | 33 | 7 | 40 |
2022 December | 35 | 14 | 49 |
2022 November | 44 | 20 | 64 |
2022 October | 37 | 18 | 55 |
2022 September | 50 | 19 | 69 |
2022 August | 27 | 21 | 48 |
2022 July | 36 | 38 | 74 |
2022 June | 29 | 19 | 48 |
2022 May | 25 | 29 | 54 |
2022 April | 32 | 22 | 54 |
2022 March | 20 | 27 | 47 |
2022 February | 26 | 26 | 52 |
2022 January | 31 | 20 | 51 |
2021 December | 26 | 30 | 56 |
2021 November | 44 | 31 | 75 |
2021 October | 41 | 36 | 77 |
2021 September | 34 | 26 | 60 |
2021 August | 55 | 29 | 84 |
2021 July | 24 | 31 | 55 |
2021 June | 37 | 14 | 51 |
2021 May | 40 | 38 | 78 |
2021 April | 102 | 53 | 155 |
2021 March | 52 | 17 | 69 |
2021 February | 65 | 26 | 91 |
2021 January | 37 | 11 | 48 |
2020 December | 49 | 13 | 62 |
2020 November | 47 | 12 | 59 |
2020 October | 60 | 17 | 77 |
2020 September | 46 | 9 | 55 |
2020 August | 44 | 6 | 50 |
2020 July | 51 | 14 | 65 |
2020 June | 43 | 9 | 52 |
2020 May | 62 | 9 | 71 |
2020 April | 55 | 25 | 80 |
2020 March | 73 | 7 | 80 |
2020 February | 123 | 35 | 158 |
2020 January | 58 | 8 | 66 |
2019 December | 43 | 2 | 45 |
2019 November | 50 | 18 | 68 |
2019 October | 30 | 13 | 43 |
2019 September | 40 | 14 | 54 |
2019 August | 29 | 7 | 36 |
2019 July | 20 | 12 | 32 |
2019 June | 30 | 11 | 41 |
2019 May | 23 | 15 | 38 |
2019 April | 22 | 17 | 39 |
2019 March | 27 | 5 | 32 |
2019 February | 41 | 10 | 51 |
2019 January | 28 | 9 | 37 |
2018 December | 38 | 11 | 49 |
2018 November | 68 | 8 | 76 |
2018 October | 165 | 23 | 188 |
2018 September | 45 | 10 | 55 |
2018 August | 28 | 9 | 37 |
2018 July | 18 | 2 | 20 |
2018 June | 22 | 5 | 27 |
2018 May | 28 | 6 | 34 |
2018 April | 33 | 3 | 36 |
2018 March | 47 | 12 | 59 |
2018 February | 21 | 5 | 26 |
2018 January | 14 | 5 | 19 |
2017 December | 34 | 5 | 39 |
2017 November | 18 | 3 | 21 |
2017 October | 18 | 11 | 29 |
2017 September | 26 | 9 | 35 |
2017 August | 18 | 15 | 33 |
2017 July | 19 | 15 | 34 |
2017 June | 24 | 15 | 39 |
2017 May | 36 | 7 | 43 |
2017 April | 26 | 1 | 27 |
2017 March | 29 | 24 | 53 |
2017 February | 37 | 20 | 57 |
2017 January | 38 | 5 | 43 |
2016 December | 44 | 6 | 50 |
2016 November | 42 | 7 | 49 |
2016 October | 33 | 13 | 46 |
2016 September | 28 | 9 | 37 |
2016 August | 16 | 1 | 17 |
2016 July | 31 | 19 | 50 |
2016 June | 7 | 10 | 17 |