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Image in Cardiology
A rare cause of subendocardial ischemia
Uma causa rara de isquemia subendocárdica
Inês Almeidaa,
Corresponding author
inesalm@gmail.com

Corresponding author.
, Marta Madeiraa, Francisca Caetanoa, Catarina Faustinoa, Luís Semedob, Lino Gonçalvesa
a Serviço de Cardiologia, Centro Hospitalar e Universitário de Coimbra, Hospital Geral, Coimbra, Portugal
b Serviço de Cardiologia, Hospital Distrital da Figueira da Foz, Figueira da Foz, Portugal
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        "titulo" => "Uma causa rara de isquemia subendoc&#225;rdica"
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          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Electrocardiogram&#58; &#40;A&#41; baseline&#59; &#40;B&#41; during episode of chest pain&#44; showing diffuse ST depression with a maximum of 7 mm in V4&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Severe periprosthetic regurgitation is a rare but potentially serious complication of valve surgery&#46; It can present clinically as heart failure&#44; hemolytic anemia or infective endocarditis&#46; The diagnosis is normally suspected following transthoracic echocardiography&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 78-year-old woman with paroxysmal atrial fibrillation had undergone aortic valve replacement with a mechanical prosthesis 10 years previously and was under oral anticoagulation&#46; She had recently been hospitalized for chest pain with anterior ST elevation&#46; Coronary angiography revealed no epicardial coronary disease but showed what appeared to be a thrombus in the distal anterior descending artery&#59; aortography showed moderate aortic regurgitation&#46; Echocardiography revealed elevated transvalvular gradients&#44; suggestive of mismatch and&#47;or increased flow&#44; and mild regurgitation &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>&#41;&#46; The setting was interpreted as embolic infarction&#46; The patient was discharged with indication for close monitoring of INR&#44; and transesophageal echocardiography was scheduled to assess valve function&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">She was re-admitted two weeks later for recurrence of intense chest pain&#44; together with autonomic symptoms and marked ST depression &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>&#41;&#44; which did not respond to medical therapy&#46; Repeat cardiac catheterization excluded coronary artery disease and showed good disc opening of the prosthetic valve and severe aortic regurgitation &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#41;&#46; Thoracic computed tomography angiography excluded acute aortic syndrome&#46; Transesophageal echocardiography showed severe periprosthetic regurgitation &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Figure 4</a>&#41;&#46; The patient was referred for cardiac surgery&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Diagnosing periprosthetic regurgitation can be a challenge when the clinical presentation is atypical and transthoracic echocardiography fails to clarify the situation&#46; The resulting decrease in diastolic coronary perfusion pressure can lead to severe subendocardial ischemia&#46; In the case presented&#44; due consideration of the symptoms and use of various imaging techniques confirmed the diagnosis and enabled appropriate treatment to be planned&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical disclosures</span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Protection of human and animal subjects</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Confidentiality of data</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Right to privacy and informed consent</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflicts of interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Transthoracic echocardiography showing&#58; &#40;A&#41; mechanical aortic valve &#40;21-mm Medtronic<span class="elsevierStyleSup">&#174;</span> with mild regurgitation&#44; possibly periprosthetic&#59; &#40;B&#41; elevated transvalvular gradients &#40;maximum 51 mmHg and mean 24 mmHg&#41;&#59; acceleration time 89 ms&#44; left ventricular outflow tract velocity time integral&#47;aortic velocity time integral 0&#46;29 and area index 0&#46;83 cm<span class="elsevierStyleSup">2</span>&#47;m<span class="elsevierStyleSup">2</span>&#44; suggestive of mismatch and&#47;or increased flow&#46;</p>"
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Article information
ISSN: 21742049
Original language: English
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Revista Portuguesa de Cardiologia (English edition)
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