Statistics

 array:24 [
  "pii" => "S2174204915000549"
  "issn" => "21742049"
  "doi" => "10.1016/j.repce.2014.11.002"
  "estado" => "S300"
  "fechaPublicacion" => "2015-03-01"
  "aid" => "592"
  "copyright" => "Sociedade Portuguesa de Cardiologia"
  "copyrightAnyo" => "2014"
  "documento" => "simple-article"
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "crp"
  "cita" => "Rev Port Cardiol. 2015;34:215.e1-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4153
    "formatos" => array:3 [
      "EPUB" => 162
      "HTML" => 3165
      "PDF" => 826
    ]
  ]
  "Traduccion" => array:1 [
    "pt" => array:19 [
      "pii" => "S0870255115000128"
      "issn" => "08702551"
      "doi" => "10.1016/j.repc.2014.11.002"
      "estado" => "S300"
      "fechaPublicacion" => "2015-03-01"
      "aid" => "592"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "simple-article"
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "crp"
      "cita" => "Rev Port Cardiol. 2015;34:215.e1-4"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 5869
        "formatos" => array:3 [
          "EPUB" => 180
          "HTML" => 4602
          "PDF" => 1087
        ]
      ]
      "pt" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Caso Cl&#237;nico</span>"
        "titulo" => "Arterite de Takayasu&#58; a prop&#243;sito de um caso cl&#237;nico"
        "tienePdf" => "pt"
        "tieneTextoCompleto" => "pt"
        "tieneResumen" => array:2 [
          0 => "pt"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "215&#46;e1"
            "paginaFinal" => "215&#46;e4"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Takayasu arteritis revisited"
          ]
        ]
        "contieneResumen" => array:2 [
          "pt" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "pt" => true
        ]
        "contienePdf" => array:1 [
          "pt" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 2"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr2.jpeg"
                "Alto" => 905
                "Ancho" => 975
                "Tamanyo" => 112966
              ]
            ]
            "descripcion" => array:1 [
              "pt" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">TC com contraste&#58; reconstru&#231;&#227;o posterior dos vasos supra&#8208;a&#243;rticos&#44; notando&#8208;se aus&#234;ncia de preenchimento da emerg&#234;ncia da art&#233;ria subcl&#225;via esquerda com preenchimento retr&#243;grado pela art&#233;ria vertebral esquerda&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Bernardo Duque Neves, Anabela Raimundo, Tom&#225;s Appleton Figueira, Francisco Pereira Machado, Jos&#233; Roquette, Jo&#227;o S&#225;"
            "autores" => array:6 [
              0 => array:2 [
                "nombre" => "Bernardo"
                "apellidos" => "Duque Neves"
              ]
              1 => array:2 [
                "nombre" => "Anabela"
                "apellidos" => "Raimundo"
              ]
              2 => array:2 [
                "nombre" => "Tom&#225;s"
                "apellidos" => "Appleton Figueira"
              ]
              3 => array:2 [
                "nombre" => "Francisco"
                "apellidos" => "Pereira Machado"
              ]
              4 => array:2 [
                "nombre" => "Jos&#233;"
                "apellidos" => "Roquette"
              ]
              5 => array:2 [
                "nombre" => "Jo&#227;o"
                "apellidos" => "S&#225;"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "pt"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2174204915000549"
          "doi" => "10.1016/j.repce.2014.11.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000549?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000128?idApp=UINPBA00004E"
      "url" => "/08702551/0000003400000003/v4_201503200652/S0870255115000128/v4_201503200652/pt/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2174204915000641"
    "issn" => "21742049"
    "doi" => "10.1016/j.repce.2015.03.009"
    "estado" => "S300"
    "fechaPublicacion" => "2015-03-01"
    "aid" => "606"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Rev Port Cardiol. 2015;34:217-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3496
      "formatos" => array:3 [
        "EPUB" => 179
        "HTML" => 2822
        "PDF" => 495
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Image In Cardiology</span>"
      "titulo" => "Elective percutaneous coronary intervention complicated by coronary rupture"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "217"
          "paginaFinal" => "218"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Interven&#231;&#227;o coron&#225;ria percut&#226;nea eletiva complicada por rotura coron&#225;ria"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0015"
          "etiqueta" => "Figure 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 1509
              "Ancho" => 1504
              "Tamanyo" => 161534
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Coronary angiogram after stent graft implantation showing sealing of the LAD rupture area and loss of the second diagonal branch &#40;arrows&#41;&#46; LAD&#58; left anterior descending artery&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Carlos Galv&#227;o Braga, Juliana Martins, Carina Arantes, Gl&#243;ria Abreu, Jo&#227;o Costa, Jorge Marques"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Carlos Galv&#227;o"
              "apellidos" => "Braga"
            ]
            1 => array:2 [
              "nombre" => "Juliana"
              "apellidos" => "Martins"
            ]
            2 => array:2 [
              "nombre" => "Carina"
              "apellidos" => "Arantes"
            ]
            3 => array:2 [
              "nombre" => "Gl&#243;ria"
              "apellidos" => "Abreu"
            ]
            4 => array:2 [
              "nombre" => "Jo&#227;o"
              "apellidos" => "Costa"
            ]
            5 => array:2 [
              "nombre" => "Jorge"
              "apellidos" => "Marques"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S0870255115000414"
        "doi" => "10.1016/j.repc.2014.11.006"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000414?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000641?idApp=UINPBA00004E"
    "url" => "/21742049/0000003400000003/v2_201504010220/S2174204915000641/v2_201504010220/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S217420491500063X"
    "issn" => "21742049"
    "doi" => "10.1016/j.repce.2015.03.008"
    "estado" => "S300"
    "fechaPublicacion" => "2015-03-01"
    "aid" => "605"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "simple-article"
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Rev Port Cardiol. 2015;34:213&#46;e1-3"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2752
      "formatos" => array:3 [
        "EPUB" => 140
        "HTML" => 2165
        "PDF" => 447
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
      "titulo" => "Sealing a ruptured non-culprit coronary plaque in a patient with acute myocardial infarction with bioresorbable vascular scaffolds"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "213&#46;e1"
          "paginaFinal" => "213&#46;e3"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Selar com suportes vasculares bioabsorv&#237;veis a rotura de uma placa coron&#225;ria n&#227;o culpada num doente com enfarte agudo do mioc&#225;rdio"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1603
              "Ancho" => 2465
              "Tamanyo" => 631664
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Optical coherence tomography&#46; &#40;A&#41; A ruptured cap and a large posterior cavity &#40;&#43;&#41; are visualized&#59; &#40;B and C&#41; images showing a lipid plaque &#40;L&#41; and a large red thrombus &#40;T&#41; protruding into the coronary lumen &#40;arrows&#41;&#59; &#40;D&#41; longitudinal reconstruction highlighting the ruptured plaque cavity &#40;&#43;&#41; in the flow direction&#46; GC&#58; guiding catheter&#59; &#42;&#58; wire artefact&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Javier Cuesta, Fernando Rivero, Teresa Bastante, Amparo Benedicto, Guillermo Diego, Fernando Alfonso"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Javier"
              "apellidos" => "Cuesta"
            ]
            1 => array:2 [
              "nombre" => "Fernando"
              "apellidos" => "Rivero"
            ]
            2 => array:2 [
              "nombre" => "Teresa"
              "apellidos" => "Bastante"
            ]
            3 => array:2 [
              "nombre" => "Amparo"
              "apellidos" => "Benedicto"
            ]
            4 => array:2 [
              "nombre" => "Guillermo"
              "apellidos" => "Diego"
            ]
            5 => array:2 [
              "nombre" => "Fernando"
              "apellidos" => "Alfonso"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S0870255115000402"
        "doi" => "10.1016/j.repc.2014.08.029"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000402?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217420491500063X?idApp=UINPBA00004E"
    "url" => "/21742049/0000003400000003/v2_201504010220/S217420491500063X/v2_201504010220/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
    "titulo" => "Takayasu arteritis revisited"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "215&#46;e1"
        "paginaFinal" => "215&#46;e4"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Bernardo Duque Neves, Anabela Raimundo, Tom&#225;s Appleton Figueira, Francisco Pereira Machado, Jos&#233; Roquette, Jo&#227;o S&#225;"
        "autores" => array:6 [
          0 => array:4 [
            "nombre" => "Bernardo"
            "apellidos" => "Duque Neves"
            "email" => array:1 [
              0 => "bernardo&#46;neves&#64;hospitaldaluz&#46;pt"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Anabela"
            "apellidos" => "Raimundo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Tom&#225;s"
            "apellidos" => "Appleton Figueira"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Francisco"
            "apellidos" => "Pereira Machado"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Jos&#233;"
            "apellidos" => "Roquette"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Jo&#227;o"
            "apellidos" => "S&#225;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Departamento de Medicina Interna e Medicina Intensiva&#44; Hospital da Luz&#44; Lisboa&#44; Portugal"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Departamento de Radiologia de Interven&#231;&#227;o&#44; Hospital da Luz&#44; Lisboa&#44; Portugal"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Centro Cardiovascular&#44; Hospital da Luz&#44; Lisboa&#44; Portugal"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Arterite de Takayasu&#58; a prop&#243;sito de um caso cl&#237;nico"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 950
            "Ancho" => 950
            "Tamanyo" => 101358
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Angiography of the abdominal aorta revealing preocclusive stenosis of the left and right renal arteries&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Takayasu arteritis is a rare vasculitis that mainly affects females before the age of 50&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">1</span></a> Clinical presentation varies according to the territories affected&#59; the left subclavian artery is most often involved&#44; followed by the aorta and the carotid&#44; renal and vertebral arteries&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">2</span></a> Coronary artery involvement is well documented&#44; but revascularization of coronary lesions is a challenge if the underlying disease is not controlled&#46; Since there are no markers specific to the disease&#44; in most cases diagnosis is based on identification of vascular lesions in imaging studies of patients with suggestive symptoms&#46; Age of onset under 40&#44; limb claudication&#44; differences in pulses and systolic blood pressure between the arms&#44; murmur over the subclavian arteries and stenosis of the great vessels on angiography are the diagnostic criteria used to distinguish Takayasu arteritis from the other vasculitides&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">1</span></a></p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Case report</span><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of a 47-year-old woman&#44; white&#44; with a history of hypertension and chronic iron deficiency anemia but no other known medical history&#46; Three weeks before admission she began to suffer chest pain radiating to the jaw&#44; relieved by rest&#46; Following assessment at another institution she was prescribed aspirin&#44; transdermal nitroglycerin and nebivolol and was referred for urgent cardiological consultation&#46; Worsening symptoms in the previous 48 hours prompted her to go to the emergency department of our hospital&#44; where on admission she was eupneic and hypertensive&#44; with pain triggered by minimal exertion and a II&#47;VI apical systolic murmur&#59; there were no other alterations on physical examination&#46; Laboratory tests showed normocytic normochromic anemia with hemoglobin 10&#46;4 g&#47;dl and elevated troponin &#40;rising from 0&#46;21 to 0&#46;32 ng&#47;dl&#41;&#46; Serial ECGs revealed dynamic repolarization changes without ST-T segment elevation&#44; while echocardiography showed mild concentric ventricular hypertrophy but no wall motion abnormalities&#44; and ejection fraction was normal&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">She was provisionally diagnosed with non-ST-elevation acute coronary syndrome and underwent urgent coronary angiography&#44; which revealed stenosis in the ostium of the left main but no other lesions&#46; During double bypass surgery &#40;left internal mammary-anterior descending and saphenous vein-obtuse marginal&#41;&#44; findings suggestive of aortitis were observed&#44; and so a biopsy was performed&#44; and anatomopathological study showed a nonspecific lymphoplasmacytic inflammatory infiltrate&#46; Syphilis serology was negative&#46; Postoperative recovery was uneventful and no further investigation was carried out&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Around four months later&#44; there was recurrence of exertional angina&#46; At this time a difference in blood pressure between the arms was noted &#40;20 mmHg less in the left arm&#41;&#44; with a very weak pulse on the left and evident skin pallor immediately after exertion or when raising the left arm&#46; Laboratory testing showed slight thrombocytosis and a rise in erythrocyte sedimentation rate to 100 mm&#47;h&#46; Echocardiography revealed new-onset hypokinesia of the left ventricular inferior wall&#44; and coronary angiography was repeated&#44; which showed preocclusive lesions of the right coronary artery and ostial saphenous graft&#46; She underwent percutaneous coronary intervention with placement of two drug-eluting stents&#59; during the procedure occlusion of the left subclavian artery was observed with retrograde filling from the ipsilateral vertebral artery &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>&#41;&#44; which raised the suspicion of Takayasu arteritis&#46; Cranial computed tomography &#40;CT&#41; angiography confirmed proximal occlusion of the left subclavian artery upstream of the origin of the left vertebral artery &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>&#41;&#44; an atheromatous plaque in the distal segment of the right common carotid causing preocclusive stenosis of the external carotid&#44; and tortuosity and kinking of the cervical course of the internal right carotid artery&#46; Carotid Doppler ultrasound showed coiling of the right internal carotid and 70&#37; stenosis&#44; preocclusive stenosis of the right external carotid and reversal of flow in the left vertebral artery caused by left subclavian steal&#46; Abdominal Doppler ultrasound detected no abnormalities in the renal arteries and the patient did not present nitrogen retention&#46; In view of these findings and fulfillment of the diagnostic criteria&#44; a diagnosis of Takayasu arteritis was made and therapy was begun with oral prednisolone 1 mg&#47;kg&#47;day&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">She remained asymptomatic until around a month later&#44; when she was readmitted twice in 15 days for acute hypertensive pulmonary edema&#46; Laboratory tests revealed deterioration of renal function but inflammatory parameters were still normal&#46; Stress echocardiography showed no wall motion abnormalities&#59; given the suspicion of renal involvement of the vasculitis in view of persistent severe renal dysfunction despite optimization of blood volume and suspension of nephrotoxic medication&#44; abdominal Doppler ultrasound was repeated&#46; This showed the abdominal aorta with irregularly thickened walls but normal flow and stenotic lesions with marked hemodynamic repercussions at the origin of the superior mesenteric artery and left renal artery&#46; Abdominal CT angiography confirmed the presence of a thin sheath of tissue surrounding the abdominal aorta&#44; causing significant preocclusive stenosis of both renal arteries and the superior mesenteric aorta &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#41;&#46; Stenoses of around 50&#37; were also detected in the inferior mesenteric artery and the celiac trunk&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">Given the obvious progression of the disease under corticoid therapy&#44; treatment with cyclophosphamide pulses was begun and angioplasty of the renal arteries and celiac trunk was performed&#44; with a good angiographic result and complete recovery of renal function&#46; The patient has remained under corticoid therapy&#44; without further complications or evidence of disease progression in other arterial territories&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Discussion and Conclusion</span><p id="par0035" class="elsevierStylePara elsevierViewall">The case described is a classic example of the severity of Takayasu arteritis and of the complexity of its diagnosis and treatment&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The disease typically presents in women aged under 50&#44; although several recent series have reported a high prevalence in older age-groups&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">3</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Its clinical presentation is varied&#59; patients can be asymptomatic for several years and can present with nonspecific systemic symptoms such as fever&#44; asthenia&#44; arthralgia&#44; myalgia and night sweats&#44; and more rarely with acute vascular events&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">4</span></a> Depending on the arterial territory affected&#44; there may be visual disturbances&#44; headache&#44; syncope&#44; Raynaud phenomenon&#44; limb claudication or differences in pulses and blood pressure between the arms&#46;<a class="elsevierStyleCrossRefs" href="#bib0070"><span class="elsevierStyleSup">2&#44;4</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">The clinical presentation in this case was coronary disease&#44; which is seen in up to a third of Takayasu patients<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">5</span></a> and is usually due to occlusion of the coronary ostia caused by aortitis&#44; although several cases of coronary arteritis have been reported without ostial involvement&#46;<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">6&#44;7</span></a> Its etiopathogenesis is unclear but some authors have suggested that as well as formation of stenoses&#44; the inflammation itself accelerates coronary atherosclerosis&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">8</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">Hypertension is a common comorbidity&#44; found in 33&#8211;83&#37; of cases&#44;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">4</span></a> linked to renal artery stenosis &#40;observed in 20&#8211;38&#37; of patients&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">6</span></a> Although there is disagreement concerning the treatment of these lesions&#44; percutaneous angioplasty has shown good long-term results in terms of treating hypertension and improving renal function&#46;<a class="elsevierStyleCrossRefs" href="#bib0070"><span class="elsevierStyleSup">2&#44;6</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">The restenosis rate varies according to the location and degree of control of the disease&#46; Interventions should preferably be performed outside periods of acute disease activity&#46;<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">9</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">Another important aspect of this case was disease progression under corticoid therapy&#44; despite normalization of inflammatory parameters&#46; Several authors have reported low sensitivity of laboratory monitoring in Takayasu arteritis and have suggested serial imaging studies to monitor disease progression&#46;<a class="elsevierStyleCrossRefs" href="#bib0110"><span class="elsevierStyleSup">10&#44;11</span></a> In around 50&#37; of cases corticoid therapy alone is insufficient to halt progression of the vasculitis and additional immunosuppressive therapy is needed&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">2</span></a> In the case reported here&#44; prolonged remission was achieved with cyclophosphamide pulses&#46; There is no consensus concerning the best drug for corticoid-resistant disease&#59; experience with cyclophosphamide in Takayasu arteritis is limited&#44; unlike in other forms of vasculitis&#46;<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">6&#44;12</span></a></p><p id="par0070" class="elsevierStylePara elsevierViewall">This case report illustrates how Takayasu arteritis remains a diagnostic and therapeutic challenge&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Ethical disclosures</span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Protection of human and animal subjects</span><p id="par0075" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Confidentiality of data</span><p id="par0080" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Right to privacy and informed consent</span><p id="par0085" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conflicts of interest</span><p id="par0090" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:10 [
        0 => array:3 [
          "identificador" => "xres469294"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec491907"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres469295"
          "titulo" => "Resumo"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0010"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec491906"
          "titulo" => "Palavras-chave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Case report"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion and Conclusion"
        ]
        7 => array:3 [
          "identificador" => "sec0020"
          "titulo" => "Ethical disclosures"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Protection of human and animal subjects"
            ]
            1 => array:2 [
              "identificador" => "sec0030"
              "titulo" => "Confidentiality of data"
            ]
            2 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Right to privacy and informed consent"
            ]
          ]
        ]
        8 => array:2 [
          "identificador" => "sec0040"
          "titulo" => "Conflicts of interest"
        ]
        9 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2014-09-01"
    "fechaAceptado" => "2014-11-15"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec491907"
          "palabras" => array:5 [
            0 => "Takayasu arteritis"
            1 => "Large vessel vasculitis"
            2 => "Vasculitis"
            3 => "Cyclophosphamide"
            4 => "Coronary artery disease"
          ]
        ]
      ]
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec491906"
          "palabras" => array:5 [
            0 => "Arterite de Takayasu"
            1 => "Vasculite de grandes vasos"
            2 => "Vasculite"
            3 => "Ciclofosfamida"
            4 => "Doen&#231;a coron&#225;ria"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Takayasu arteritis is a large vessel vasculitis with various clinical presentations depending on the territories affected&#46; We report the case of a 47-year-old woman who was diagnosed with Takayasu arteritis following rapid progression of coronary disease&#46; The condition evolved rapidly under corticosteroid therapy&#44; with formation of new arterial stenoses within the carotid and splanchnic circulations&#46; Disease remission was achieved with cyclophosphamide pulses and percutaneous angioplasty of the affected vessels was performed&#46;</p></span>"
      ]
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A arterite de Takayasu &#233; uma vasculite de grandes vasos que cursa com apresenta&#231;&#245;es cl&#237;nicas diversas consoante os territ&#243;rios afetados&#46; Apresenta-se o caso cl&#237;nico de uma mulher de 47 anos a quem foi feito o diagn&#243;stico de arterite de Takayasu na sequ&#234;ncia de doen&#231;a coron&#225;ria rapidamente progressiva&#46; O quadro evoluiu rapidamente&#44; sob corticoterapia&#44; com forma&#231;&#227;o de estenoses a n&#237;vel da circula&#231;&#227;o carot&#237;dea e espl&#226;ncnica&#44; tendo-se conseguido estabiliza&#231;&#227;o da doen&#231;a com pulsos de ciclofosfamida e angioplastia percut&#226;nea das les&#245;es&#46;</p></span>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Duque Neves B&#44; Raimundo A&#44; Appleton Figueira T&#44; et al&#46; Arterite de Takayasu&#58; a prop&#243;sito de um caso cl&#237;nico&#46; Rev Port Cardiol&#46; 2015&#59;34&#58;215&#46;e1&#8211;215&#46;e4&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 882
            "Ancho" => 1851
            "Tamanyo" => 191852
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Aortography showing stenosis of the left subclavian artery &#40;A&#41; and retrograde filling by the ipsilateral vertebral artery &#40;B&#41;&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 975
            "Ancho" => 975
            "Tamanyo" => 120514
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Contrast computed tomography&#58; posterior reconstruction of the supra-aortic vessels&#46; Note the absence of filling at the emergence of the left subclavian artery&#44; with retrograde filling from the left vertebral artery&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 950
            "Ancho" => 950
            "Tamanyo" => 101358
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Angiography of the abdominal aorta revealing preocclusive stenosis of the left and right renal arteries&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:12 [
            0 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46;C&#46; Jennette"
                            1 => "R&#46;J&#46; Falk"
                            2 => "P&#46;A&#46; Bacon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/art.37715"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arthritis Rheumatism"
                        "fecha" => "2013"
                        "volumen" => "65"
                        "paginaInicial" => "1"
                        "paginaFinal" => "11"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23045170"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Takayasu&#39;s arteritis&#58; a review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46; Maffei"
                            1 => "M&#46; Di Renzo"
                            2 => "G&#46; Bova"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Intern Emerg Med"
                        "fecha" => "2006"
                        "volumen" => "1"
                        "paginaInicial" => "105"
                        "paginaFinal" => "112"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17111782"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of large-vessel vasculidities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "B&#46;L&#46; Richards"
                            1 => "L&#46; March"
                            2 => "S&#46;E&#46; Gabriel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.berh.2010.10.008"
                      "Revista" => array:6 [
                        "tituloSerie" => "Best Pract Res Clin Rheumatol"
                        "fecha" => "2010"
                        "volumen" => "24"
                        "paginaInicial" => "871"
                        "paginaFinal" => "883"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21665132"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Takayasu arteritis&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;L&#46; Johnston"
                            1 => "R&#46;J&#46; Lock"
                            2 => "M&#46;M&#46; Gompels"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Pathol"
                        "fecha" => "2002"
                        "volumen" => "55"
                        "paginaInicial" => "481"
                        "paginaFinal" => "486"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12101189"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Coronary involvement in Takayasu&#39;s arteritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Rav-Acha"
                            1 => "L&#46; Plot"
                            2 => "N&#46; Peled"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Autoimmunity Rev"
                        "fecha" => "2007"
                        "volumen" => "6"
                        "paginaInicial" => "566"
                        "paginaFinal" => "571"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment and outcomes of large vessel arteritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46;A&#46; Borg"
                            1 => "B&#46; Dasgupta"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.berh.2009.04.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Best Pract Res Clin Rheumatol"
                        "fecha" => "2009"
                        "volumen" => "23"
                        "paginaInicial" => "325"
                        "paginaFinal" => "337"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19508941"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A case of Takayasu arteritis with repeated coronary artery restenosis after drug-eluting stent implantation successfully treated with a combination of steroids"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "K&#46; Yokota"
                            1 => "M&#46; Shimpo"
                            2 => "T&#46; Iwata"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Intern Med"
                        "fecha" => "2012"
                        "volumen" => "51"
                        "paginaInicial" => "739"
                        "paginaFinal" => "743"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22466830"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atherosclerosis in Takayasu arteritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "E&#46; Seyahi"
                            1 => "S&#46; Ugurlu"
                            2 => "R&#46; Cumali"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/ard.2005.047498"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Rheum Dis"
                        "fecha" => "2006"
                        "volumen" => "65"
                        "paginaInicial" => "1202"
                        "paginaFinal" => "1207"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16439439"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Optimizing the outcome of vascular intervention for Takayasu arteritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;H&#46; Perera"
                            1 => "T&#46; Youngstein"
                            2 => "R&#46;G&#46;J&#46; Gibbs"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/bjs.9372"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "2014"
                        "volumen" => "101"
                        "paginaInicial" => "43"
                        "paginaFinal" => "50"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24375298"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Role of inflammatory markers in Takayasu arteritis disease monitoring"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46;E&#46; O&#8217;Connor"
                            1 => "H&#46;E&#46; Carpenter"
                            2 => "S&#46; Bidari"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1471-2377-14-62"
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Neurol"
                        "fecha" => "2014"
                        "volumen" => "14"
                        "paginaInicial" => "62"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24678735"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of disease activity and progression in Takayasu&#39;s arteritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46; Direskeneli"
                            1 => "S&#46;Z&#46; Aydin"
                            2 => "P&#46;A&#46; Merkel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Clin Exp Rheumatol"
                        "fecha" => "2011"
                        "volumen" => "29"
                        "numero" => "Suppl 64"
                        "paginaInicial" => "S86"
                        "paginaFinal" => "S91"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21586201"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cyclophosphamide for large vessel vasculitis&#58; assessment of response by PET&#47;CT"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46;C&#46; Henes"
                            1 => "M&#46; Mueller"
                            2 => "C&#46; Pfannenberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Clin Exp Rheumatol"
                        "fecha" => "2011"
                        "volumen" => "29"
                        "numero" => "Suppl 64"
                        "paginaInicial" => "S43"
                        "paginaFinal" => "S48"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21385544"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21742049/0000003400000003/v2_201504010220/S2174204915000549/v2_201504010220/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9919"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Reports"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21742049/0000003400000003/v2_201504010220/S2174204915000549/v2_201504010220/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000549?idApp=UINPBA00004E"
]