was read the article
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Mapeamento endocárdico à esquerda e epicárdico à direita. Eletrograma endocárdico (esquerda em baixo) e epicárdico (direita em baixo) mostrando maior precocidade no sinal epicárdico (62<span class="elsevierStyleHsp" style=""></span>ms vs 80<span class="elsevierStyleHsp" style=""></span>ms).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Pedro Galvão Santos, Diogo Cavaco, Pedro Adragão, Mauricio Scanavacca, Katya Reis Santos, Francisco Belo Morgado, Pedro Carmo, Francisco Costa, Ricardo Bernardo, Manuela Nunes, Miguel Abecasis, José Neves, Miguel Mendes" "autores" => array:13 [ 0 => array:2 [ "nombre" => "Pedro" "apellidos" => "Galvão Santos" ] 1 => array:2 [ "nombre" => "Diogo" "apellidos" => "Cavaco" ] 2 => array:2 [ "nombre" => "Pedro" "apellidos" => "Adragão" ] 3 => array:2 [ "nombre" => "Mauricio" "apellidos" => "Scanavacca" ] 4 => array:2 [ "nombre" => "Katya" "apellidos" => "Reis Santos" ] 5 => array:2 [ "nombre" => "Francisco" "apellidos" => "Belo Morgado" ] 6 => array:2 [ "nombre" => "Pedro" "apellidos" => "Carmo" 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"/08702551/0000003300000005/v1_201406210043/S0870255114000134/v1_201406210043/pt/main.assets" ] ] "itemSiguiente" => array:20 [ "pii" => "S2174204914001238" "issn" => "21742049" "doi" => "10.1016/j.repce.2013.10.046" "estado" => "S300" "fechaPublicacion" => "2014-05-01" "aid" => "464" "copyright" => "Sociedade Portuguesa de Cardiologia" "documento" => "article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Cardiol. 2014;33:281-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3407 "formatos" => array:3 [ "EPUB" => 190 "HTML" => 2593 "PDF" => 624 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>" "titulo" => "New-onset atrial fibrillation during acute coronary syndromes: Predictors and prognosis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => 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class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 8 => array:3 [ "nombre" => "Ricardo" "apellidos" => "Bernardo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 9 => array:3 [ "nombre" => "Manuela" "apellidos" => "Nunes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 10 => array:3 [ "nombre" => "Miguel" "apellidos" => "Abecasis" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 11 => array:3 [ "nombre" => "José" "apellidos" => "Neves" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 12 => array:3 [ "nombre" => "Miguel" "apellidos" => "Mendes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Serviço de Cardiologia, Centro Hospitalar de Lisboa Ocidental, Hospital de Santa Cruz, Carnaxide, Portugal" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Instituto do Coração (InCor), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Ablação epicárdica percutânea em arritmias ventriculares" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1585 "Ancho" => 1500 "Tamanyo" => 200507 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Insertion of guidewire in the pericardial space following subxiphoid puncture.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Ventricular arrhythmias are a leading cause of morbidity and sudden death. Treatment can include medical therapy, implantable cardioverter-defibrillators (ICDs) and ablation. ICDs are effective in interrupting sustained ventricular tachycardia (VT) or ventricular fibrillation (VF), and thus in preventing sudden death. Nevertheless, they do not alter the underlying arrhythmogenic substrate.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Ablation by the application of energy is the only option to eliminate or modify VT circuits.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Percutaneous ablation is a useful technique for the treatment of VT in patients with structural heart disease or in those with ICDs receiving multiple shocks. It was first attempted in 1983,<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> since when significant advances have been made. Success rates in structural heart disease range between 50% and 70% in different series,<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,4</span></a> and depend on various factors including the center's experience, the ability to identify the circuit responsible and the etiology of the underlying disease.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Ablation usually consists of the application of radio-frequency energy in the area of the endocardium shown by mapping to be responsible for sustaining the arrhythmia. The rate of VT recurrence after endocardial ablation in patients with ischemic heart disease (IHD) is approximately 50%.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5,6</span></a> One limitation of this approach is difficulty in locating the reentrant circuit; at times, it is impossible to treat the critical zone of the circuit if this is located in the subendocardium or epicardium. Epicardial circuits are identified in 10–30% of patients with IHD and in over 30% of those with non-ischemic VT.<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7,8</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Epicardial mapping and ablation were initially only possible by cardiac surgery, but in 1996, Sosa et al. described a percutaneous technique.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a></p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Objective</span><p id="par0025" class="elsevierStylePara elsevierViewall">The aim of this study is to describe the experience of the Arrhythmia Unit of the Cardiology Department of Hospital de Santa Cruz in the epicardial mapping and ablation of ventricular arrhythmias, in what we believe is the first series reported in Portugal.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Methods</span><p id="par0030" class="elsevierStylePara elsevierViewall">Of a total of 95 VT ablations in our institution from 2004 to 2012, percutaneous epicardial access was attempted in nine patients, eight male, mean age 58±12 years. Only two patients presented cardiovascular risk factors (hypertension and dyslipidemia) and none had serious comorbidities such as chronic renal failure, pulmonary disease or peripheral arterial disease. Most had been diagnosed with dilated cardiomyopathy (DCM) and had previously undergone endocardial ablation. Five patients had ICDs, three for primary and two for secondary prevention.</p><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Procedure</span><p id="par0035" class="elsevierStylePara elsevierViewall">Procedures were performed under conscious sedation with a perfusion of propofol 2 mg/kg/h and remifentanil <0.2 μg/kg/min in all cases, adjusted to the specific needs of each patient. Patients’ O<span class="elsevierStyleInf">2</span> Sat and expired CO<span class="elsevierStyleInf">2</span> levels were monitored by capnography. In all cases, catheters were placed in the coronary sinus and the right ventricle, and withdrawn to the most proximal area when a His bundle electrogram was required. Access to the epicardial space was not possible in one patient due to the presence of adhesions; in six patients specifically referred for an epicardial procedure following recurrent VT or a failed first procedure it was achieved at the first attempt, while in two it was performed after endocardial mapping during the procedure suggested an epicardial origin.</p><p id="par0040" class="elsevierStylePara elsevierViewall">Pericardial access was obtained through percutaneous subxiphoid puncture with a Tuohy needle (or pericardiocentesis needle) as described by Sosa et al.<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">9,10</span></a> The puncture was made between the left margin of the xiphoid appendix and the lower margin of the adjacent rib with the needle directed towards the left shoulder (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>). Correct positioning was confirmed by visualization of a small quantity of contrast (∼1 ml) in the epicardial space, after which a guidewire was inserted (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>). An introducer was passed over the guidewire, followed by the ablation catheter.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> After access to the epicardial space was obtained, intravenous heparin (100 U/kg) was administered to enable coronary angiography and endocardial ablation to be performed safely. Once within the epicardial space, the catheter can be manipulated to map the entire epicardial surface<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> (<a class="elsevierStyleCrossRefs" href="#fig0015">Figures 3 and 4</a>). A 4-mm catheter was used in the first two cases, while an irrigated catheter was used in the other six. In all cases the ablation strategy was to identify the critical isthmus involved in sustaining the tachycardia with the aid of electroanatomical mapping (CARTO system, Biosense Webster). The radiofrequency parameters employed depended on the type of catheter – 20–50 W for the 4-mm catheter and 15–30 W for the irrigated catheter (8–15 cc/min). During the procedure, the epicardial space was drained using a pigtail catheter for set periods of approximately 15 min, adjusted to the needs of the patient, and after the procedure, by means of an introducer for occasional aspiration over a maximum period of three hours. No patient required corticosteroids or anti-inflammatory drugs.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">The mapping and ablation techniques were similar to those used in the endocardial space, although entrainment maneuvers are more difficult using bipolar pacing due to the high epicardial stimulation threshold. On electroanatomical mapping, areas with bipolar voltage of less than 0.1 mV were considered to be scar tissue. All patients with monomorphic VT with different morphologies had one clinically dominant morphology, which was selected for ablation.</p><p id="par0050" class="elsevierStylePara elsevierViewall">Patients were hospitalized for 24 hours. Post-procedure echocardiography was performed only in patients with suggestive symptoms; none presented pericardial effusion. All patients underwent coronary angiography prior to radio-frequency ablation to assess proximity to the coronary arteries (energy was applied only >5 mm from a coronary artery). During the procedures, pacing (28 mA at 2 ms) was performed along the left ventricular lateral wall to capture the left phrenic nerve on three-dimensional mapping in order to avoid injury during energy application.</p><p id="par0055" class="elsevierStylePara elsevierViewall">We compared the number of events in the six months prior to the epicardial procedure and six months after. Arrhythmic events and ICD shocks were recorded, mainly through device interrogation but also through ECG and 24-hour Holter monitoring.</p></span></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Results</span><p id="par0060" class="elsevierStylePara elsevierViewall">Percutaneous subxiphoid access was achieved in eight patients. Epicardial ablation was performed in six as second-line therapy after previous endocardial procedures failed and as a combined procedure in two. The etiology of the arrhythmia was non-ischemic in seven and ischemic in one. In the four patients with idiopathic DCM, posteroseptal, posterolateral or anterolateral scars were identified by voltage criteria in all cases; one Brazilian immigrant living in Portugal for five years had Chagas disease, one patient had IHD in the dilated phase with significant left ventricular dysfunction, one had tachycardiomyopathy, and one had symptomatic frequent ventricular extrasystoles (24<span class="elsevierStyleHsp" style=""></span>730 on 24-hour Holter ECG) of the right ventricular outflow tract. All patients were under antiarrhythmic therapy and in NYHA class II or III, and five had an ICD (<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>). No patient had undergone cardiac surgery.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0065" class="elsevierStylePara elsevierViewall">In one case, the presence of adhesions prevented epicardial access and so the procedure was halted. In the patient with frequent ventricular extrasystoles, the application of radiofrequency energy was ineffective, probably due to the presence of epicardial fat. Of the eight patients in whom epicardial access was achieved, six underwent epicardial ablation. On average, two VTs were induced per patient, epicardial circuits being identified in 75%. In seven cases (six during application in the pericardial space), the VT was interrupted during radiofrequency application and could not be re-induced, an immediate success rate of 87.5%. The patient with Chagas disease was diagnosed with stroke following an episode of left hemiparesis one week after a combined ablation procedure, with no sequelae. There were no other procedure-related complications.</p><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Follow-up</span><p id="par0070" class="elsevierStylePara elsevierViewall">All patients were alive after a mean follow-up of 3.5±1.2 years (six months to six years). Comparison of the number of events in the six months prior to the procedure and six months after showed a decrease in the number of VT episodes and ICD shocks. In the four patients with DCM, two were free of sustained VT episodes during follow-up, and in the other two there was a significant reduction not only in arrhythmic events but also in ICD shocks. The patient with Chagas disease had no new episodes of sustained VT following epicardial ablation. No significant symptomatic relief was achieved in the patient with frequent ventricular extrasystoles, probably due to the presence of epicardial fat. The patient with tachycardiomyopathy is event-free, with improved ejection fraction (>55%), and the patient with IHD has had a reduced number of events. In those with longer follow-up, the trend for fewer events has been maintained (<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>).</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">The two patients with the longest follow-up (six years) presented no long-term complications secondary to the procedure.</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Discussion</span><p id="par0080" class="elsevierStylePara elsevierViewall">There was a high success rate of symptom relief in our study population, with a low rate of complications. Despite the complications reported in other studies and multicenter analyses (5% major complications in the acute phase and 2% in the long term),<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> the risk appears justified in selected cases since there is no alternative treatment for epicardial reentrant circuits. The main underlying diseases associated with this type of circuit are non-ischemic DCM, followed by right ventricular arrhythmogenic dysplasia, and ischemic cardiomyopathy.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> Careful patient selection is essential to avoid complications, since patients who have undergone previous cardiac surgery (a relative contraindication), valve surgery or coronary revascularization present a greater risk of adhesions and difficulty in achieving access to the pericardial space, and therefore a higher risk of right ventricular puncture or other complications. Use of a Tuohy needle, contrast injection and long guidewires that ensure that no cardiac chamber is perforated increase the efficacy of the procedure and, more importantly, significantly reduce the risk of complications.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Since percutaneous epicardial VT ablation is a relatively recent technique, there have been no studies as yet on possible adverse coronary effects in the long term. Nevertheless, there is agreement that a good compromise between risk and benefit is achieved when the radiofrequency energy is applied at a distance of least 5 mm from the coronary arteries.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Due to the risk of intimal hyperplasia and thrombosis, application in the vicinity of the coronary arteries should be performed with caution.<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">12,13</span></a> There was no case of myocardial infarction in our study population.</p><p id="par0085" class="elsevierStylePara elsevierViewall">The greatest risk when undertaking subxiphoid puncture to access the epicardial space is of perforating intraperitoneal structures such as the liver, stomach or large intestine, especially in patients with DCM or hepatomegaly, but none of these complications occurred in our series.</p><p id="par0090" class="elsevierStylePara elsevierViewall">Other possible complications, with rates of less than 1%,<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> include bleeding, pericardial effusion or tamponade and ventricular wall rupture, which were also not seen in our population.</p><p id="par0095" class="elsevierStylePara elsevierViewall">The substrate for the development of sustained monomorphic VT is areas of ventricular scarring that promote reentrant circuits. In IHD, these areas of fibrosis are generally found in the endocardium, which facilitates ablation, explaining the greater success achieved in such cases. In non-ischemic DCM, low-voltage areas are more difficult to identify on electroanatomical mapping, as at times they are not in the endocardium, which complicates the procedure and often requires a different approach.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> In the cases of idiopathic DCM in our series, voltage mapping was able to identify scarring in the posteroseptal, posterolateral and anteroseptal regions, the latter in one case only. Unlike in IHD, in which most infarct scars are clearly located in the endocardial wall,<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> DCM most often presents with subendocardial or epicardial scarring. In these cases, identifying the scar responsible for the tachycardia for the purposes of ablation may only be possible via an epicardial approach.<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> In Chagas disease a hybrid epicardial and endocardial approach should be adopted from the outset, given that there is a 70% probability of an epicardial circuit.<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> However, given the small number of patients with Chagas disease, such cases are not high on the list of interventions. Despite advances in epicardial voltage mapping techniques, percutaneous ablation of tachycardia of ischemic etiology with a single endocardial substrate still has higher success rates.<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">16,18</span></a></p><p id="par0100" class="elsevierStylePara elsevierViewall">The presence of epicardial fat affected the efficacy of radiofrequency ablation in one of our patients. This is a common problem, more frequently seen in patients with coronary disease, that reduces the procedure's efficacy, even with irrigated catheters.<a class="elsevierStyleCrossRefs" href="#bib0095"><span class="elsevierStyleSup">19,20</span></a></p><p id="par0105" class="elsevierStylePara elsevierViewall">The question remains as to which patients will benefit most from the technique. Various criteria have been proposed to raise the level of suspicion of an epicardial origin of an arrhythmia, all of which are based on the principle that conduction velocities are slower when the circuit is in the epicardial region (giving rise to initial slurring of the QRS) than when the endocardial surface is involved. These criteria (for example a pseudo delta wave during the VT) do not have high sensitivity or specificity,<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">21</span></a> and it is debatable whether they are of value.<a class="elsevierStyleCrossRefs" href="#bib0110"><span class="elsevierStyleSup">22,23</span></a> In our series, we selected patients in whom endocardial ablation had already been attempted, irrespective of QRS morphology during tachycardia. Given the high prevalence of epicardial scarring in Chagas disease, an epicardial approach was chosen from the outset in this patient.</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Conclusions</span><p id="par0110" class="elsevierStylePara elsevierViewall">There are clear advantages of an epicardial approach to VT ablation in selected patients, with a low risk of complications.</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Ethical disclosures</span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Protection of human and animal subjects</span><p id="par0115" class="elsevierStylePara elsevierViewall">The authors declare that the procedures followed were in accordance with the regulations of the relevant clinical research ethics committee and with those of the Code of Ethics of the World Medical Association (Declaration of Helsinki).</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Confidentiality of data</span><p id="par0120" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data.</p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">Right to privacy and informed consent</span><p id="par0125" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article. The corresponding author is in possession of this document.</p></span></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">Conflicts of interest</span><p id="par0130" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:13 [ 0 => array:2 [ "identificador" => "xres350690" "titulo" => array:6 [ 0 => "Abstract" 1 => "Introduction" 2 => "Objective" 3 => "Methods" 4 => "Results" 5 => "Conclusions" ] ] 1 => array:2 [ "identificador" => "xpalclavsec332247" "titulo" => "Keywords" ] 2 => array:2 [ "identificador" => "xres350689" "titulo" => array:6 [ 0 => "Resumo" 1 => "Introdução" 2 => "Objetivo" 3 => "População e métodos" 4 => "Resultados" 5 => "Conclusões" ] ] 3 => array:2 [ "identificador" => "xpalclavsec332246" "titulo" => "Palavras-chave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Objective" ] 6 => array:3 [ "identificador" => "sec0015" "titulo" => "Methods" "secciones" => array:1 [ 0 => array:2 [ "identificador" => "sec0020" "titulo" => "Procedure" ] ] ] 7 => array:3 [ "identificador" => "sec0025" "titulo" => "Results" "secciones" => array:1 [ 0 => array:2 [ "identificador" => "sec0030" "titulo" => "Follow-up" ] ] ] 8 => array:2 [ "identificador" => "sec0035" "titulo" => "Discussion" ] 9 => array:2 [ "identificador" => "sec0040" "titulo" => "Conclusions" ] 10 => array:3 [ "identificador" => "sec0045" "titulo" => "Ethical disclosures" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0050" "titulo" => "Protection of human and animal subjects" ] 1 => array:2 [ "identificador" => "sec0055" "titulo" => "Confidentiality of data" ] 2 => array:2 [ "identificador" => "sec0060" "titulo" => "Right to privacy and informed consent" ] ] ] 11 => array:2 [ "identificador" => "sec0065" "titulo" => "Conflicts of interest" ] 12 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2012-09-24" "fechaAceptado" => "2013-10-26" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec332247" "palabras" => array:3 [ 0 => "Ventricular tachycardia" 1 => "Epicardial mapping" 2 => "Catheter ablation" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec332246" "palabras" => array:3 [ 0 => "Taquicardia ventricular" 1 => "Mapeamento epicárdico" 2 => "Ablação por cateter" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Reentrant circuits of ventricular tachycardia may involve not only the endocardium but also the epicardium. Epicardial ablation can be useful in these situations.</p> <span class="elsevierStyleSectionTitle" id="sect0015">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The aim of this study was to assess efficacy, safety and complications in a series of consecutive patients who underwent ablation of ventricular tachycardia with epicardial mapping.</p> <span class="elsevierStyleSectionTitle" id="sect0020">Methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The study included all patients undergoing ventricular tachycardia ablation with epicardial mapping from 2004 to 2012. Of a total of 95 ablations, an epicardial approach was attempted in nine patients, eight male, mean age 58±12 years. Endocardial mapping was performed in all patients previously or simultaneously. The etiology of the arrhythmia was non-ischemic in eight patients and ischemic in one. We compared the number of events in the six months prior to the epicardial procedure and six months after.</p> <span class="elsevierStyleSectionTitle" id="sect0025">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Percutaneous epicardial access was achieved in eight patients. In one case it was not possible due to the presence of adhesions. In none of the patients was the procedure repeated and there were no major complications during hospitalization. In a mean follow-up of 3.5±1.2 years, one patient suffered stroke; there were no other medium-to-long-term complications and the number of ventricular tachycardia episodes was reduced in all patients after ablation.</p> <span class="elsevierStyleSectionTitle" id="sect0030">Conclusions</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Epicardial radiofrequency ablation of ventricular tachycardia was effective in reducing morbidity in eight patients, with a low risk of complications in the short and medium-to-long term.</p>" ] "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span class="elsevierStyleSectionTitle" id="sect0040">Introdução</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Os circuitos de reentrada da taquicardia ventricular envolvem, por vezes, não só o endocárdio, mas também o epicárdio. A ablação de taquicardia ventricular por via epicárdica pode ser útil nessas situações.</p> <span class="elsevierStyleSectionTitle" id="sect0045">Objetivo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">O objetivo do estudo consistiu em avaliar a eficácia, segurança e complicações de uma série doentes consecutivos submetidos a ablação de arritmias ventriculares com mapeamento por via epicárdica.</p> <span class="elsevierStyleSectionTitle" id="sect0050">População e métodos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Foram incluídos no estudo todos os doentes submetidos a ablação de taquicardia ventricular com mapeamento por via epicárdica desde 2004 até 2012. De um total de 95 ablações, em nove doentes foi tentada a via epicárdica, oito do sexo masculino com 58 ± 12 anos. Todos os doentes tinham sido previamente submetidos ou realizaram concomitantemente mapeamento endocárdico. A etiologia da arritmia era não isquémica em oito doentes e isquémica num. Comparou-se o número de eventos nos seis meses anteriores ao procedimento epicárdico com os seis meses seguintes.</p> <span class="elsevierStyleSectionTitle" id="sect0055">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">O acesso epicárdico foi conseguido em oito doentes por via percutânea subxifoideia. Num caso não foi possível abordagem epicárdica por presença de aderências. Em nenhum dos doentes o procedimento foi repetido e não se verificaram complicações <span class="elsevierStyleItalic">major</span> no período intra-hospitalar. Num seguimento médio de 3,5 ± 1,2 anos registou-se um acidente vascular cerebral num doente, não se registando outras complicações a médio/longo prazo, tendo a maioria dos doentes diminuído o número de episódios de taquicardia ventricular após ablação.</p> <span class="elsevierStyleSectionTitle" id="sect0060">Conclusões</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">A ablação de taquicardia ventricular por via epicárdica foi utilizada eficazmente na diminuição da morbilidade em oito doentes com baixo risco de complicações a médio/longo prazo.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Galvão Santos P, Cavaco D, Adragão P, et al. Ablação epicárdica percutânea em arritmias ventriculares. Rev Port Cardiol. 2014;33:273–279.</p>" ] ] "multimedia" => array:6 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1188 "Ancho" => 1583 "Tamanyo" => 178942 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Subxiphoid puncture towards the left shoulder.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1585 "Ancho" => 1500 "Tamanyo" => 200507 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Insertion of guidewire in the pericardial space following subxiphoid puncture.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1538 "Ancho" => 1500 "Tamanyo" => 275201 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Manipulation of mapping/ablation catheter in the pericardial space guided by coronary angiography.</p>" ] ] 3 => array:7 [ "identificador" => "fig0020" "etiqueta" => "Figure 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 2885 "Ancho" => 3000 "Tamanyo" => 744310 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Images from CARTO mapping system: endocardial mapping (top left) and epicardial mapping (top right). Endocardial electrogram (bottom left) and epicardial electrogram (bottom right) showing earlier epicardial signal (62 ms vs. 80 ms).</p>" ] ] 4 => array:7 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "leyenda" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">DCM: dilated cardiomyopathy; F: female; ICD: implantable cardioverter-defibrillator; M: male; NYHA: New York Heart Association class; RVOT: right ventricular outflow tract; VES: ventricular extrasystoles; VT: ventricular tachycardia.</p>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Gender \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Underlying disease \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">ICD at time of ablation \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Previous endocardial ablation \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Type of arrhythmia \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Cardiovascular risk factors \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Ejection fraction \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">NYHA at time of ablation \t\t\t\t\t\t\n \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Idiopathic DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Yes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Monomorphic VT (>1 morphology) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Yes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><35% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">III \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Idiopathic DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Yes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Monomorphic VT (>1 morphology) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">40% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">II \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Ischemic<span class="elsevierStyleHsp" style=""></span>cardiomyopathy \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Yes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Monomorphic VT \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Yes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><35% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">II \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Idiopathic DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Yes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Monomorphic VT \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><35% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">II \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Idiopathic DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Monomorphic VT (>1 morphology) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">42% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">II \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">RVOT VES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">VES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">>55% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">F \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Chagas disease \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Yes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Monomorphic VT \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">45% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Tachycardiomyopathy \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Monomorphic VT \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">No \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">42% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">III \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab524491.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Characteristics of population undergoing epicardial ablation.</p>" ] ] 5 => array:7 [ "identificador" => "tbl0010" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "leyenda" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">DCM: dilated cardiomyopathy; Endo: endocardial; Epi: epicardial; F: female; M: male; NSVT: non-sustained ventricular tachycardia; RF: radiofrequency; RVOT VES: right ventricular outflow tract ventricular extrasystoles; TCM: tachycardiomyopathy; VT: ventricular tachycardia.</p>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Disease \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Gender \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">RF application \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">VT before (6 months before) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">VT after (6 months after) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Shocks before (6 months before) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Shocks after (6 months after) \t\t\t\t\t\t\n \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Epi/Endo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">>10 (>10) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">NSVT \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5 (5) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Epi/Endo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">>10 (8) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (2) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 (2) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Epi/Endo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">>10 (>10) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 (2) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 (3) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 (1) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Endo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (2) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">TCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Epi/Endo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 (3) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Ischemic DCM \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Endo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5 (3) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 (3) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 (1) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">RVOT VES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Epi/Endo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">– \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Chagas \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">F \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Epi/Endo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 (2) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">NSVT \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (1) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab524492.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Results before and after epicardial ablation.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from cardiac arrest: the Cardiac Arrest Study Hamburg (CASH)" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "K.H. 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Year/Month | Html | Total | |
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2024 November | 7 | 9 | 16 |
2024 October | 31 | 30 | 61 |
2024 September | 56 | 23 | 79 |
2024 August | 47 | 25 | 72 |
2024 July | 40 | 24 | 64 |
2024 June | 28 | 17 | 45 |
2024 May | 37 | 51 | 88 |
2024 April | 27 | 44 | 71 |
2024 March | 41 | 36 | 77 |
2024 February | 34 | 55 | 89 |
2024 January | 36 | 64 | 100 |
2023 December | 34 | 46 | 80 |
2023 November | 32 | 35 | 67 |
2023 October | 25 | 14 | 39 |
2023 September | 25 | 24 | 49 |
2023 August | 26 | 17 | 43 |
2023 July | 26 | 11 | 37 |
2023 June | 32 | 11 | 43 |
2023 May | 47 | 22 | 69 |
2023 April | 24 | 7 | 31 |
2023 March | 39 | 20 | 59 |
2023 February | 35 | 22 | 57 |
2023 January | 30 | 19 | 49 |
2022 December | 33 | 20 | 53 |
2022 November | 43 | 32 | 75 |
2022 October | 41 | 31 | 72 |
2022 September | 37 | 31 | 68 |
2022 August | 38 | 40 | 78 |
2022 July | 38 | 34 | 72 |
2022 June | 39 | 23 | 62 |
2022 May | 33 | 33 | 66 |
2022 April | 32 | 24 | 56 |
2022 March | 34 | 32 | 66 |
2022 February | 23 | 17 | 40 |
2022 January | 35 | 34 | 69 |
2021 December | 28 | 35 | 63 |
2021 November | 37 | 35 | 72 |
2021 October | 54 | 35 | 89 |
2021 September | 37 | 25 | 62 |
2021 August | 34 | 32 | 66 |
2021 July | 33 | 31 | 64 |
2021 June | 31 | 15 | 46 |
2021 May | 28 | 44 | 72 |
2021 April | 46 | 48 | 94 |
2021 March | 66 | 31 | 97 |
2021 February | 59 | 14 | 73 |
2021 January | 32 | 13 | 45 |
2020 December | 47 | 8 | 55 |
2020 November | 29 | 22 | 51 |
2020 October | 21 | 13 | 34 |
2020 September | 53 | 8 | 61 |
2020 August | 23 | 8 | 31 |
2020 July | 42 | 5 | 47 |
2020 June | 36 | 4 | 40 |
2020 May | 39 | 7 | 46 |
2020 April | 35 | 6 | 41 |
2020 March | 37 | 4 | 41 |
2020 February | 87 | 25 | 112 |
2020 January | 31 | 13 | 44 |
2019 December | 24 | 4 | 28 |
2019 November | 28 | 2 | 30 |
2019 October | 33 | 3 | 36 |
2019 September | 20 | 15 | 35 |
2019 August | 31 | 6 | 37 |
2019 July | 35 | 14 | 49 |
2019 June | 35 | 10 | 45 |
2019 May | 45 | 39 | 84 |
2019 April | 44 | 12 | 56 |
2019 March | 86 | 12 | 98 |
2019 February | 103 | 13 | 116 |
2019 January | 90 | 8 | 98 |
2018 December | 59 | 9 | 68 |
2018 November | 103 | 13 | 116 |
2018 October | 197 | 11 | 208 |
2018 September | 52 | 10 | 62 |
2018 August | 81 | 7 | 88 |
2018 July | 44 | 5 | 49 |
2018 June | 67 | 6 | 73 |
2018 May | 54 | 11 | 65 |
2018 April | 95 | 3 | 98 |
2018 March | 65 | 6 | 71 |
2018 February | 67 | 4 | 71 |
2018 January | 48 | 9 | 57 |
2017 December | 110 | 9 | 119 |
2017 November | 42 | 6 | 48 |
2017 October | 51 | 13 | 64 |
2017 September | 37 | 14 | 51 |
2017 August | 43 | 13 | 56 |
2017 July | 45 | 12 | 57 |
2017 June | 51 | 8 | 59 |
2017 May | 67 | 13 | 80 |
2017 April | 47 | 10 | 57 |
2017 March | 37 | 2 | 39 |
2017 February | 56 | 10 | 66 |
2017 January | 26 | 1 | 27 |
2016 December | 44 | 16 | 60 |
2016 November | 39 | 7 | 46 |
2016 October | 49 | 5 | 54 |
2016 September | 36 | 7 | 43 |
2016 August | 13 | 1 | 14 |
2016 July | 15 | 6 | 21 |
2016 June | 10 | 9 | 19 |
2016 May | 10 | 4 | 14 |
2016 April | 38 | 2 | 40 |
2016 March | 62 | 7 | 69 |
2016 February | 76 | 19 | 95 |
2016 January | 68 | 20 | 88 |
2015 December | 65 | 9 | 74 |
2015 November | 61 | 10 | 71 |
2015 October | 73 | 9 | 82 |
2015 September | 69 | 18 | 87 |
2015 August | 58 | 9 | 67 |
2015 July | 59 | 7 | 66 |
2015 June | 42 | 11 | 53 |
2015 May | 55 | 11 | 66 |
2015 April | 53 | 12 | 65 |
2015 March | 38 | 4 | 42 |
2015 February | 54 | 5 | 59 |
2015 January | 48 | 11 | 59 |
2014 December | 66 | 13 | 79 |
2014 November | 44 | 9 | 53 |
2014 October | 53 | 15 | 68 |
2014 September | 64 | 16 | 80 |
2014 August | 47 | 17 | 64 |
2014 July | 90 | 30 | 120 |