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Vol. 31. Issue 3.
Pages 247-250 (March 2012)
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Vol. 31. Issue 3.
Pages 247-250 (March 2012)
Case report
Open Access
Cardiac 123I-MIBG scintigraphy and arrhythmic risk in left ventricular noncompaction
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5076
Sílvia Marta Oliveiraa,b,
Corresponding author
silviamartaoliveira@hotmail.com

Corresponding author.
, Elisabete Martinsa,b, Ana Oliveirac, Teresa Pinhoa,b, Cristina Gavinaa,b, Teresa Fariac, José Carlos Silva-Cardosoa,b, Jorge Pereirac, Maria Júlia Maciela,b
a Cardiology Department, Hospital de São João, Porto, Portugal
b Faculty of Medicine, Porto University, Porto, Portugal
c Nuclear Medicine Department, Hospital de São João, Porto, Portugal
This item has received

Under a Creative Commons license
Article information
Abstract

Left ventricular noncompaction is an unusual but increasingly recognized cardiomy-opathy, the etiology of which is still not definitely established. Clinical presentation includes a wide spectrum of scenarios, including heart failure, thromboembolism and malignant arrhyth-mias, with half of deaths occurring suddenly. Early detection of LVNC is therefore essential to prevent sudden cardiac death. To our knowledge, this is the first report of the presence of cardiac sympathetic nervous dysfunction, assessed by 123iodine-metaiodobenzylguanidine myocardial scintigraphy, in a patient with LVNC, preserved left ventricular systolic function and exercise-induced nonsustained ventricular tachycardia. This finding may be related to the increased arrhythmic risk observed in this cardiomyopathy, giving a new insight into the pathophysiology of LVNC.

Keywords:
Cardiac 123I-MIBG scintigraphy
Left ventricular noncompaction
Arrhythmias
Keywords:
Cintigrafia cardíaca com 123I-MIBG
Miocárdio não-compactado
Arritmias
Resumo

O miocárdio não-compactado (MNC) é uma miocardiopatia que, embora rara, tem sido gradualmente mais descrita. O espectro de apresentac, ão clínica é variável, incluindo insufi-ciência cardíaca, fenómenos tromboembólicos e arritmias, sendo que metade das mortes ocorre subitamente (MSC). Por conseguinte, o diagnóstico precoce e correto do MNC é fundamental para a prevenc¸ão da MSC. O presente artigo ilustra pela primeira vez a presenc¸a de disfunc¸ão neuronal simpática, avaliada por cintigrafia cardíaca com 123I-metaiodobenzilguinadina, num doente com MNC, func¸ão sistólica ventricular esquerda preservada e taquicardia não susten-tada induzida pelo esforc¸o. A presenc¸a de alterac¸ões na actividade adrenérgica cardíaca pode estar relacionada com o maior risco arrítmico característico desta miocardiopatia, podendo contribuir para o melhor esclarecimento da sua patofisiologia.

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