Response to the Letter to the Editor – “The PARADIGM-HF population may be very different from real-world heart failure patients” Gustavo Rodrigues, António Tralhão, Carlos Aguiar, Pedro Freitas, António Ventosa, Miguel Mendes

Is the PARADIGM-HF cohort representative of the real-world heart failure patient population? Gustavo Rodrigues, António Tralhão, Carlos Aguiar, Pedro Freitas, António Ventosa, Miguel Mendes

Neurohormonal modulation: The new paradigm of pharmacological treatment of heart failure J. Silva-Cardoso, D. Brás, F. Canário-Almeida, A. Andrade, L. Oliveira, F. Pádua, C. Fonseca, N. Bragança, S. Carvalho, R. Soares, J. Ferreira Santos