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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Acromegaly is a rare disease and our knowledge of acromegalic cardiomyopathy is moderate&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a> It is&#44; however&#44; very important for cardiologists to know that cardiovascular disease accounts for more than 50&#37; of all deaths in acromegaly&#46; Typical findings in acromegalic cardiomyopathy that should alert us include concentric left ventricular &#40;LV&#41; hypertrophy and progressive systolic dysfunction&#46; These patients also suffer from hypertension&#44; coronary artery disease&#44; arrhythmias and valvular disease&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">2</span></a> The other most common cardiovascular risk factors in these patients are diabetes mellitus and sleep apnea syndrome&#46; It is therefore clear that these patients will need cardiological expertise in addition to support from endocrinologists&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Studies of myocardial function in acromegalic cardiomyopathy are welcome in order to increase our knowledge base&#44; and the study by Korm&#225;nyos et al&#46; published in this issue of the <span class="elsevierStyleItalic">Journal</span> adds to our understanding of this disease&#44; but it also raise some questions that merit a closer look&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">3</span></a> Their main findings were LV hypertrophy and impaired LV diastolic function with preserved LV systolic dysfunction&#46; LV systolic function was assessed by ejection fraction &#40;EF&#41; and different strain measures&#46; Radial strain was enhanced compared to normals&#44; while longitudinal and circumferential strains were similar to those in normal individuals&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The apparently divergent messages from their strain measures &#8211; enhanced radial thickening and normal longitudinal strain &#8211; call for comment&#46; Patients with acromegaly had thicker septums and larger LV cavities than normal individuals&#46; A thicker interventricular septum and posterior wall will normally lead to reduced LV longitudinal function&#44; but this was not found in their study&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">4</span></a> The explanation may be that the thickness was not very pronounced&#44; and that the larger LV cavity could compensate for this relationship&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Longitudinal strain is considered the most robust and reproducible form of strain&#44; while radial strain is considered less reproducible when using two-dimensional imaging&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">5&#44;6</span></a> The authors used three-dimensional strain&#44; which is still considered a research tool&#44; and one should therefore be wary of drawing firm conclusions about the apparently enhanced radial function&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The results from Korm&#225;nyos et al&#46;&#8217;s study are seemingly different from those of another recent study on myocardial function in acromegaly&#46; Popielarz-Grygalewicz et al&#46; assessed 140 patients and found that global longitudinal strain &#40;GLS&#41; indicated marginally worse LV function compared to their control group&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a> Their patient characteristics were&#44; however&#44; different from the population of the study published here&#46; Those patients had much thicker LV walls and were therefore at a more advanced stage in the progression of acromegalic cardiomyopathy&#46; Their findings were also somewhat surprising&#44; since GLS was only marginally lower and thus relatively intact&#44; despite being significantly different from their controls&#46; We will therefore need more studies of LV mechanics in acromegaly before we can apply myocardial strain in these patients&#46; A finding of reduced myocardial function by strain and normal EF is normally considered an early sign of myocardial disease&#44; whereas Korm&#225;nyos et al&#46; report normal strain despite other signs of diseased myocardium in their patients&#46; Their findings of normal systolic strains are therefore positive for the acromegalic population in their cohort&#44; but cannot of course be extrapolated to all patients with acromegaly&#46; <span class="elsevierStyleSmallCaps">I</span> therefore recommend that treatment decisions following echocardiographic studies should be based on traditional measures until we have obtained more knowledge on how to interpret myocardial function by strain in acromegaly&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The author has no conflicts of interest to declare&#46;</p></span></span>"
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How to interpret assessment of left ventricular function by strain in acromegaly?
Como interpreter a avalição da função ventricular esquerda por strain na acromegália?
Thor Edvardsen
Department of Cardiology, Oslo University Hospital, Rikshospitalet, and University of Oslo, Oslo, Norway
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            "apellidos" => "Edvardsen"
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              0 => "thor.edvardsen@medisin.uio.no"
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            "entidad" => "Department of Cardiology&#44; Oslo University Hospital&#44; Rikshospitalet&#44; and University of Oslo&#44; Oslo&#44; Norway"
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    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Como interpreter a avali&#231;&#227;o da fun&#231;&#227;o ventricular esquerda por <span class="elsevierStyleItalic">strain</span> na acromeg&#225;lia&#63;"
      ]
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Acromegaly is a rare disease and our knowledge of acromegalic cardiomyopathy is moderate&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a> It is&#44; however&#44; very important for cardiologists to know that cardiovascular disease accounts for more than 50&#37; of all deaths in acromegaly&#46; Typical findings in acromegalic cardiomyopathy that should alert us include concentric left ventricular &#40;LV&#41; hypertrophy and progressive systolic dysfunction&#46; These patients also suffer from hypertension&#44; coronary artery disease&#44; arrhythmias and valvular disease&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">2</span></a> The other most common cardiovascular risk factors in these patients are diabetes mellitus and sleep apnea syndrome&#46; It is therefore clear that these patients will need cardiological expertise in addition to support from endocrinologists&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Studies of myocardial function in acromegalic cardiomyopathy are welcome in order to increase our knowledge base&#44; and the study by Korm&#225;nyos et al&#46; published in this issue of the <span class="elsevierStyleItalic">Journal</span> adds to our understanding of this disease&#44; but it also raise some questions that merit a closer look&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">3</span></a> Their main findings were LV hypertrophy and impaired LV diastolic function with preserved LV systolic dysfunction&#46; LV systolic function was assessed by ejection fraction &#40;EF&#41; and different strain measures&#46; Radial strain was enhanced compared to normals&#44; while longitudinal and circumferential strains were similar to those in normal individuals&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The apparently divergent messages from their strain measures &#8211; enhanced radial thickening and normal longitudinal strain &#8211; call for comment&#46; Patients with acromegaly had thicker septums and larger LV cavities than normal individuals&#46; A thicker interventricular septum and posterior wall will normally lead to reduced LV longitudinal function&#44; but this was not found in their study&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">4</span></a> The explanation may be that the thickness was not very pronounced&#44; and that the larger LV cavity could compensate for this relationship&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Longitudinal strain is considered the most robust and reproducible form of strain&#44; while radial strain is considered less reproducible when using two-dimensional imaging&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">5&#44;6</span></a> The authors used three-dimensional strain&#44; which is still considered a research tool&#44; and one should therefore be wary of drawing firm conclusions about the apparently enhanced radial function&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The results from Korm&#225;nyos et al&#46;&#8217;s study are seemingly different from those of another recent study on myocardial function in acromegaly&#46; Popielarz-Grygalewicz et al&#46; assessed 140 patients and found that global longitudinal strain &#40;GLS&#41; indicated marginally worse LV function compared to their control group&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a> Their patient characteristics were&#44; however&#44; different from the population of the study published here&#46; Those patients had much thicker LV walls and were therefore at a more advanced stage in the progression of acromegalic cardiomyopathy&#46; Their findings were also somewhat surprising&#44; since GLS was only marginally lower and thus relatively intact&#44; despite being significantly different from their controls&#46; We will therefore need more studies of LV mechanics in acromegaly before we can apply myocardial strain in these patients&#46; A finding of reduced myocardial function by strain and normal EF is normally considered an early sign of myocardial disease&#44; whereas Korm&#225;nyos et al&#46; report normal strain despite other signs of diseased myocardium in their patients&#46; Their findings of normal systolic strains are therefore positive for the acromegalic population in their cohort&#44; but cannot of course be extrapolated to all patients with acromegaly&#46; <span class="elsevierStyleSmallCaps">I</span> therefore recommend that treatment decisions following echocardiographic studies should be based on traditional measures until we have obtained more knowledge on how to interpret myocardial function by strain in acromegaly&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The author has no conflicts of interest to declare&#46;</p></span></span>"
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                      "titulo" => "Acromegalic cardiomyopathy&#58; an overview of risk factors clinical manifestations&#44; and therapeutic options"
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                          "autores" => array:3 [
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              "identificador" => "bib0050"
              "etiqueta" => "2"
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                          "autores" => array:3 [
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                      "doi" => "10.1530/ERC-17-0253"
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                        "tituloSerie" => "Endocr Relat Cancer"
                        "fecha" => "2017"
                        "volumen" => "24"
                        "paginaInicial" => "505"
                        "paginaFinal" => "518"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28733467"
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                      "doi" => "10.1016/j.repc.2019.08.010"
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                        "tituloSerie" => "Rev Port Cardiol&#46;"
                        "fecha" => "2020"
                        "volumen" => "39"
                        "paginaInicial" => "189"
                        "paginaFinal" => "196"
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                          "autores" => array:3 [
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jacc.2017.06.046"
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                        "tituloSerie" => "J Am Coll Cardiol"
                        "fecha" => "2017"
                        "volumen" => "70"
                        "paginaInicial" => "942"
                        "paginaFinal" => "954"
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                    0 => array:2 [
                      "titulo" => "EACVI-ASE-Industry Standardization Task Force&#46; Variability and reproducibility of segmental longitudinal strain measurement&#58; a report from the EACVI-ASE strain standardization task force"
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                      "doi" => "10.1016/j.jcmg.2017.01.027"
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                        "tituloSerie" => "JACC Cardiovasc Imaging"
                        "fecha" => "2018"
                        "volumen" => "11"
                        "paginaInicial" => "15"
                        "paginaFinal" => "24"
                        "link" => array:1 [
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                    0 => array:2 [
                      "titulo" => "Imaging assessment of ventricular mechanics"
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                            0 => "T&#46; Edvardsen"
                            1 => "K&#46;H&#46; Haugaa"
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                    ]
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                        "tituloSerie" => "Heart Br Card Soc"
                        "fecha" => "2011"
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                      "titulo" => "The thorny way of 3D strain from research to clinical use&#58; are we getting closer&#63;"
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ISSN: 21742049
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Revista Portuguesa de Cardiologia (English edition)
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