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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Despite progress in prosthetic valve manufacturing and the different types of valves that have appeared in the last two decades&#44; the ideal replacement valve is yet to be found&#46; Stentless aortic bioprosthetic valves were introduced to overcome some of the disadvantages of stented valves&#44; particularly to improve hemodynamics&#44; by increasing the effective orifice area&#44; and to increase durability&#46; Despite some enthusiasm&#44; the greater technical demands of implanting stentless aortic valves have favored the widespread use of stented valves&#44; leaving stentless valves with advantages in patients with a small aortic root or impaired left ventricular function&#44; in whom the better hemodynamics of the stentless valve may result in better long-term results&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The study by Andrade et al&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">2</span></a> published in this issue of the <span class="elsevierStyleItalic">Journal</span> describes the short- and medium-term outcomes of Freedom Solo and Solo Smart stentless aortic valves in a single-center experience&#46; The authors present a retrospective cohort involving 345 patients regardless of primary indication for surgery or concomitant procedures&#46; The perioperative results were good&#44; as was the hemodynamic performance of the valve at six months&#44; as demonstrated by the low mean gradient and large effective orifice area&#44; and also reflected in the low incidence of patient-prosthesis mismatch&#46; Concerning long-term follow-up&#44; the high survival and low rate of structural valve degeneration and endocarditis are encouraging&#44; although a period longer than six years is warranted to confirm these expectations&#46; As pointed out by the authors&#44; the results are similar to previously published findings&#44;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#44;4</span></a> and may suffer from selection bias that could affect comparisons with stented bioprostheses&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The way to change the paradigm of surgical options and bring about more widespread use of stentless valves is to prove that the more technically demanding&#44; and thus potentially riskier&#44; procedure is more beneficial to patients&#46; In fact&#44; current stentless valves are less demanding to implant&#44; due to the simplified single suture line&#46; Data comparing the Freedom Solo with stented valves have been recently published&#46; Wollersheim et al&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">5</span></a> compared outcomes of the Freedom Solo and the Mitroflow bioprosthetic valve in patients with a small aortic root&#46; Cross-clamp times for isolated replacement procedures were similar&#44; around 80 min&#44; and eight-year survival did not differ between groups&#44; although the stentless valve had an impressive 0&#37; cumulative incidence of aortic valve reoperation at seven years compared to 7&#46;1&#37; for the stented valve&#46; Christ et al&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">6</span></a> compared the hemodynamic performance of the Freedom Solo to that of a stented valve &#40;Labcor Dokimos Plus&#41; and found no significant difference in effective orifice area&#46; Finally&#44; from the same group as the present paper&#44; Cerqueira et al&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">7</span></a> compared the stentless Freedom Solo to the stented Trifecta&#46; In a propensity-matched population&#44; the stented valve showed a better hemodynamic profile&#44; although reverse remodeling and six-year survival were comparable between the groups&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Dealing with small aortic roots&#44; the potential for patient-prosthesis mismatch&#44; and the desire to improve the hemodynamics of bioprostheses have long been concerns of surgeons&#46; Aortic root enlargement to enable placement of a larger prosthesis has also proved to be feasible and effective&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">8</span></a> The sutureless aortic prosthesis recently appeared as an option with apparently excellent hemodynamics&#44; reducing cross-clamp and cardiopulmonary bypass times and facilitating minimally invasive surgery and complex cardiac interventions&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">9</span></a> The exponential growth of transcatheter aortic valve implantation has added this technique to an already complex equation&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a> While the data presented by the authors enrich the literature&#44; it is likely that only randomized trials and longer follow-up times can give a clear view of the place of the Freedom Solo stentless aortic bioprosthetic valve in valve replacement surgery&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0025" class="elsevierStylePara elsevierViewall">The author has no conflicts of interest to declare&#46;</p></span></span>"
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The place of a stentless aortic bioprosthetic valve
O lugar de uma bioprótese aórtica sem stent
Pedro M. Correia
Centro de Cirurgia Cardiotorácica, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Despite progress in prosthetic valve manufacturing and the different types of valves that have appeared in the last two decades&#44; the ideal replacement valve is yet to be found&#46; Stentless aortic bioprosthetic valves were introduced to overcome some of the disadvantages of stented valves&#44; particularly to improve hemodynamics&#44; by increasing the effective orifice area&#44; and to increase durability&#46; Despite some enthusiasm&#44; the greater technical demands of implanting stentless aortic valves have favored the widespread use of stented valves&#44; leaving stentless valves with advantages in patients with a small aortic root or impaired left ventricular function&#44; in whom the better hemodynamics of the stentless valve may result in better long-term results&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The study by Andrade et al&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">2</span></a> published in this issue of the <span class="elsevierStyleItalic">Journal</span> describes the short- and medium-term outcomes of Freedom Solo and Solo Smart stentless aortic valves in a single-center experience&#46; The authors present a retrospective cohort involving 345 patients regardless of primary indication for surgery or concomitant procedures&#46; The perioperative results were good&#44; as was the hemodynamic performance of the valve at six months&#44; as demonstrated by the low mean gradient and large effective orifice area&#44; and also reflected in the low incidence of patient-prosthesis mismatch&#46; Concerning long-term follow-up&#44; the high survival and low rate of structural valve degeneration and endocarditis are encouraging&#44; although a period longer than six years is warranted to confirm these expectations&#46; As pointed out by the authors&#44; the results are similar to previously published findings&#44;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#44;4</span></a> and may suffer from selection bias that could affect comparisons with stented bioprostheses&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The way to change the paradigm of surgical options and bring about more widespread use of stentless valves is to prove that the more technically demanding&#44; and thus potentially riskier&#44; procedure is more beneficial to patients&#46; In fact&#44; current stentless valves are less demanding to implant&#44; due to the simplified single suture line&#46; Data comparing the Freedom Solo with stented valves have been recently published&#46; Wollersheim et al&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">5</span></a> compared outcomes of the Freedom Solo and the Mitroflow bioprosthetic valve in patients with a small aortic root&#46; Cross-clamp times for isolated replacement procedures were similar&#44; around 80 min&#44; and eight-year survival did not differ between groups&#44; although the stentless valve had an impressive 0&#37; cumulative incidence of aortic valve reoperation at seven years compared to 7&#46;1&#37; for the stented valve&#46; Christ et al&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">6</span></a> compared the hemodynamic performance of the Freedom Solo to that of a stented valve &#40;Labcor Dokimos Plus&#41; and found no significant difference in effective orifice area&#46; Finally&#44; from the same group as the present paper&#44; Cerqueira et al&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">7</span></a> compared the stentless Freedom Solo to the stented Trifecta&#46; In a propensity-matched population&#44; the stented valve showed a better hemodynamic profile&#44; although reverse remodeling and six-year survival were comparable between the groups&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Dealing with small aortic roots&#44; the potential for patient-prosthesis mismatch&#44; and the desire to improve the hemodynamics of bioprostheses have long been concerns of surgeons&#46; Aortic root enlargement to enable placement of a larger prosthesis has also proved to be feasible and effective&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">8</span></a> The sutureless aortic prosthesis recently appeared as an option with apparently excellent hemodynamics&#44; reducing cross-clamp and cardiopulmonary bypass times and facilitating minimally invasive surgery and complex cardiac interventions&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">9</span></a> The exponential growth of transcatheter aortic valve implantation has added this technique to an already complex equation&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a> While the data presented by the authors enrich the literature&#44; it is likely that only randomized trials and longer follow-up times can give a clear view of the place of the Freedom Solo stentless aortic bioprosthetic valve in valve replacement surgery&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0025" class="elsevierStylePara elsevierViewall">The author has no conflicts of interest to declare&#46;</p></span></span>"
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ISSN: 21742049
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