was read the article
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"idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255118303950?idApp=UINPBA00004E" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204918302113?idApp=UINPBA00004E" "url" => "/21742049/0000003700000006/v3_201807150625/S2174204918302113/v3_201807150625/en/main.assets" ] "itemAnterior" => array:20 [ "pii" => "S2174204918302095" "issn" => "21742049" "doi" => "10.1016/j.repce.2017.03.013" "estado" => "S300" "fechaPublicacion" => "2018-06-01" "aid" => "1203" "copyright" => "Sociedade Portuguesa de Cardiologia" "documento" => "article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "sco" "cita" => "Rev Port Cardiol. 2018;37:543-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1358 "formatos" => array:3 [ "EPUB" => 120 "HTML" => 1011 "PDF" => 227 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in Cardiology</span>" "titulo" => "Intimal sarcoma of the left atrium – A rare form of mitral valve obstruction" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "543" "paginaFinal" => "544" ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Sarcoma da íntima da aurícula esquerda – uma forma rara de obstrução valvular mitral" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1419 "Ancho" => 1897 "Tamanyo" => 487750 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Panel A</span>: Apical four-chamber view showing a dilated left atrium with a large left atrial mass. <span class="elsevierStyleBold">Panel B</span>: Transmitral gradient recorded from apical approach using continuous wave Doppler across the mitral valve. A mean value of 8 mmHg and a peak of 25 mmHg were observed. <span class="elsevierStyleBold">Panel C</span>: Off-axis transesophageal image showing multilobulated mass attached to left atrial posterolateral wall. <span class="elsevierStyleBold">Panel D</span>: 12° Right Anterior Oblique, 15° caudal projection showing high vascularization of the tumor through all three major vascular beds. <span class="elsevierStyleBold">Panel E</span>: 4-chamber MRI T1-weighted image showing mass isointensity. <span class="elsevierStyleBold">Panel F</span>: 4-chamber MRI T2-weighted image depicting mass hyperintensity. <span class="elsevierStyleBold">Panel G</span>: 4-chamber MRI contrast enhanced image revealing heterogeneous uptake after gadolinium contrast administration, with low signal intensity in a central area. <span class="elsevierStyleBold">Panel H</span>: Macroscopic view of the excised tumor. <span class="elsevierStyleBold">Panel I</span>: Histopathology: (H&E, ×100) malignant neoplasm, predominantly undifferentiated, with prominent pleomorphism, with fusiform and epithelioid cells; mitotic activity and necrosis that was easy to find. <span class="elsevierStyleBold">Panel J</span>: (vimentin, ×100) – expression of vimentin in malignant cells (fusiform and epithelioid). <span class="elsevierStyleBold">Panel K</span>: (MDM2, ×100) – nuclear multifocal expression of MDM2 in malignant cells; all other markers negative (SMA, desmin, CD31, CD34, S100, FVIII, CK8/18, HMB45). <span class="elsevierStyleBold">Panel L</span>: Post-operative CT showing tumor relapse, with extensive growth into left atrium and pulmonary vein invasion.</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">CT: computed tomography; MRI: magnetic resonance imaging.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Glória Abreu, Alberto Salgado, Nuno Bettencourt, Nuno Salomé, João Ferreira, Susana Guimarães" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Glória" "apellidos" => "Abreu" ] 1 => array:2 [ "nombre" => "Alberto" "apellidos" => "Salgado" ] 2 => array:2 [ "nombre" => "Nuno" "apellidos" => "Bettencourt" ] 3 => array:2 [ "nombre" => "Nuno" "apellidos" => "Salomé" ] 4 => array:2 [ "nombre" => "João" "apellidos" => "Ferreira" ] 5 => array:2 [ "nombre" => "Susana" "apellidos" => "Guimarães" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0870255117300215" "doi" => "10.1016/j.repc.2017.03.013" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255117300215?idApp=UINPBA00004E" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204918302095?idApp=UINPBA00004E" "url" => "/21742049/0000003700000006/v3_201807150625/S2174204918302095/v3_201807150625/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in Cardiology</span>" "titulo" => "Spontaneously aborted sudden cardiac death in Brugada syndrome" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "545" "paginaFinal" => "546" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "João Português, Lucy Calvo, Filipa Canário-Almeida, Sílvia Ribeiro, Victor Sanfins, António Lourenço" "autores" => array:6 [ 0 => array:4 [ "nombre" => "João" "apellidos" => "Português" "email" => array:1 [ 0 => "joaomportugues@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Lucy" "apellidos" => "Calvo" ] 2 => array:2 [ "nombre" => "Filipa" "apellidos" => "Canário-Almeida" ] 3 => array:2 [ "nombre" => "Sílvia" "apellidos" => "Ribeiro" ] 4 => array:2 [ "nombre" => "Victor" "apellidos" => "Sanfins" ] 5 => array:2 [ "nombre" => "António" "apellidos" => "Lourenço" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Hospital Senhora da Oliveira, Guimarães, Portugal" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Morte súbita com reversão espontânea em Síndrome de Brugada" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1287 "Ancho" => 3167 "Tamanyo" => 555633 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Twelve-lead ECG performed on the 2nd intercostal space revealing a type-1 Brugada pattern.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 60-year-old woman presented with palpitations. Transthoracic echocardiography was normal, a 12-lead electrocardiogram (ECG) was unremarkable and 24-hour Holter monitoring was performed. During monitoring and while asleep, the patient experienced urinary incontinence with no other symptoms. Holter monitoring analysis (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>) revealed a nocturnal episode of polymorphic ventricular tachycardia (VT) followed by ventricular fibrillation (VF) with a duration of two and a half minutes, and asystole (38 seconds). Afterwards, sinus rhythm (SR) resumed with sinoatrial and advanced atrioventricular (AV) block. Ventricular asystole was interrupted by junctional escape beats with AV dissociation, resuming with SR with normal AV conduction. The 12-lead ECG was repeated on the 2nd intercostal space and a type-1 Brugada pattern was documented (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>). There was no evidence of fever or electrolyte imbalance and the use of a QT-prolonging drug was ruled out. Electrical monitoring during hospitalization revealed numerous episodes of monomorphic VT with left bundle branch block morphology and inferior axis (<a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>). Coronary angiography ruled out significant coronary artery disease and a cardioverter defibrillator was implanted. Electrophysiologic testing was performed with no inducible ventricular arrhythmias. Molecular analysis detected a pathogenic mutation (c.4720G>A) in exon 27 of the SCN5A gene.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Brugada patients have a high risk of sudden cardiac death (SCD) due to polymorphic VT/VF, but its true incidence is difficult to define. This case suggests that patients who appear to be asymptomatic may also experience spontaneously aborted SCD. To our knowledge, this is the first report of spontaneous and complete recovery following a long period of ventricular asystole.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0015" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:1 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of interest" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2017-01-21" "fechaAceptado" => "2017-06-11" "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1397 "Ancho" => 2500 "Tamanyo" => 453902 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Night-time Holter tracing documenting prolonged polymorphic ventricular tachycardia and ventricular fibrillation, followed by ventricular asystole and subsequent resumption of sinus rhythm.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1287 "Ancho" => 3167 "Tamanyo" => 555633 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Twelve-lead ECG performed on the 2nd intercostal space revealing a type-1 Brugada pattern.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 886 "Ancho" => 3417 "Tamanyo" => 576744 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Monomorphic ventricular tachycardia with morphology suggestive of right ventricular outflow tract origin.</p>" ] ] ] ] "idiomaDefecto" => "en" "url" => "/21742049/0000003700000006/v3_201807150625/S2174204918302101/v3_201807150625/en/main.assets" "Apartado" => array:4 [ "identificador" => "9915" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in cardiology" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21742049/0000003700000006/v3_201807150625/S2174204918302101/v3_201807150625/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204918302101?idApp=UINPBA00004E" ]
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