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array:3 [ "nombre" => "Graça" "apellidos" => "Castro" "email" => array:1 [ 0 => "castro2406@gmail.com" ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Serviço de Cardiologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Tromboembolismo venoso nos hospitais portugueses: ponto da situação e como podemos melhorar" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The fact that venous thromboembolism (VTE) is a common cardiovascular disease, particularly among hospitalized patients, with high mortality and morbidity, makes it a major public health issue. The good news is that it is the leading preventable cause of in-hospital death.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Recent years have seen great improvements in all aspects of VTE: prevention, diagnosis and therapy.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a> Aspects of VTE prevention such as identification of patients at risk and effective implementation of preventive measures probably remain the most challenging issues in this field.</p><p id="par0015" class="elsevierStylePara elsevierViewall">For the first time in Portugal a prospective study – the ARTE study<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">2</span></a> – has gathered solid and valuable information regarding VTE risk profiles and the use of prophylactic measures in hospitalized patients.</p><p id="par0020" class="elsevierStylePara elsevierViewall">A new risk score derived from the well-known scores of Caprini<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">3</span></a> and Khorana et al.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">4</span></a> was applied to a population of 4090 hospitalized patients in medical, surgical, orthopedic and oncology departments. The proposed score is designed to be applied to all types of hospitalized patients. This is a clear advantage over the standard scores, especially considering the increasing complexity of diseases. However, it should be validated by prospective and independent studies before it can be used in clinical practice.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The majority of this population (95%) were found to be at high or moderate risk for VTE. Prophylaxis was used in only 67% during hospital stay and in 29% after discharge.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Differences in population characteristics preclude direct comparisons between studies, but these findings are similar to those of the ENDORSE study,<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">5</span></a> which found similar VTE risk profiles between countries but major asymmetries in the use of recommended prophylaxis.</p><p id="par0035" class="elsevierStylePara elsevierViewall">The small number of thrombotic events reported in the ARTE study may reflect underdiagnosis. Major bleeding complications occurred in only 3.9% of inpatients under anticoagulant prophylaxis, reflecting the safety of this approach.</p><p id="par0040" class="elsevierStylePara elsevierViewall">More important is the fact that the majority of VTE events occurred after hospital discharge, probably as a result of inadequate prophylactic measures. This finding is consistent with the need for extended VTE prophylaxis, a subject now under investigation, with several studies indicating a potential benefit.<a class="elsevierStyleCrossRefs" href="#bib0070"><span class="elsevierStyleSup">6,7</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Prophylaxis rules were underused in the ARTE study, clearly illustrating the need for dissemination and implementation of guideline protocols. There are various possible ways of improving compliance with guidelines, including the use of electronic tools incorporating clinical prediction rules and risk scores.<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">The publication of the ARTE study in the current issue of the <span class="elsevierStyleItalic">Journal</span> is a valuable contribution to extending knowledge of this condition and has the potential to draw attention to the problem of VTE prophylaxis in Portugal.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The author has no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:8 [ 0 => array:3 [ "identificador" => "bib0045" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Venous thromboembolism: past, present and future" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 2 | 2 | 4 |
2024 October | 30 | 23 | 53 |
2024 September | 35 | 24 | 59 |
2024 August | 39 | 27 | 66 |
2024 July | 24 | 28 | 52 |
2024 June | 26 | 27 | 53 |
2024 May | 26 | 18 | 44 |
2024 April | 32 | 28 | 60 |
2024 March | 22 | 24 | 46 |
2024 February | 26 | 21 | 47 |
2024 January | 21 | 22 | 43 |
2023 December | 17 | 29 | 46 |
2023 November | 30 | 24 | 54 |
2023 October | 20 | 11 | 31 |
2023 September | 17 | 17 | 34 |
2023 August | 23 | 19 | 42 |
2023 July | 21 | 7 | 28 |
2023 June | 20 | 10 | 30 |
2023 May | 34 | 26 | 60 |
2023 April | 26 | 7 | 33 |
2023 March | 79 | 29 | 108 |
2023 February | 34 | 22 | 56 |
2023 January | 26 | 19 | 45 |
2022 December | 45 | 22 | 67 |
2022 November | 39 | 28 | 67 |
2022 October | 36 | 29 | 65 |
2022 September | 21 | 41 | 62 |
2022 August | 24 | 30 | 54 |
2022 July | 28 | 49 | 77 |
2022 June | 26 | 29 | 55 |
2022 May | 26 | 42 | 68 |
2022 April | 32 | 40 | 72 |
2022 March | 25 | 52 | 77 |
2022 February | 37 | 45 | 82 |
2022 January | 23 | 31 | 54 |
2021 December | 17 | 34 | 51 |
2021 November | 22 | 45 | 67 |
2021 October | 25 | 40 | 65 |
2021 September | 23 | 27 | 50 |
2021 August | 30 | 28 | 58 |
2021 July | 15 | 13 | 28 |
2021 June | 21 | 25 | 46 |
2021 May | 25 | 44 | 69 |
2021 April | 29 | 27 | 56 |
2021 March | 50 | 17 | 67 |
2021 February | 47 | 19 | 66 |
2021 January | 28 | 9 | 37 |
2020 December | 21 | 9 | 30 |
2020 November | 19 | 16 | 35 |
2020 October | 15 | 19 | 34 |
2020 September | 39 | 9 | 48 |
2020 August | 11 | 5 | 16 |
2020 July | 31 | 20 | 51 |
2020 June | 27 | 3 | 30 |
2020 May | 19 | 10 | 29 |
2020 April | 22 | 10 | 32 |
2020 March | 35 | 12 | 47 |
2020 February | 41 | 13 | 54 |
2020 January | 15 | 6 | 21 |
2019 December | 21 | 7 | 28 |
2019 November | 21 | 10 | 31 |
2019 October | 24 | 3 | 27 |
2019 September | 22 | 5 | 27 |
2019 August | 21 | 9 | 30 |
2019 July | 22 | 9 | 31 |
2019 June | 21 | 17 | 38 |
2019 May | 17 | 17 | 34 |
2019 April | 20 | 11 | 31 |
2019 March | 14 | 9 | 23 |
2019 February | 27 | 3 | 30 |
2019 January | 6 | 7 | 13 |
2018 December | 15 | 12 | 27 |
2018 November | 25 | 9 | 34 |
2018 October | 76 | 9 | 85 |
2018 September | 14 | 11 | 25 |
2018 August | 23 | 5 | 28 |
2018 July | 3 | 1 | 4 |
2018 June | 21 | 5 | 26 |
2018 May | 18 | 1 | 19 |
2018 April | 18 | 2 | 20 |
2018 March | 25 | 4 | 29 |
2018 February | 16 | 3 | 19 |
2018 January | 16 | 3 | 19 |
2017 December | 19 | 7 | 26 |