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family&#44; supporting the hypothesis of an absent or inadequate endothelization response in specific patients&#44; of unknown cause&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">3&#44;4</span></a> In our patient&#44; there was no evidence of an early residual shunt&#44; but we cannot speculate on the specific causes that may have given rise to this mid-term residual ASD&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">We adopted a percutaneous approach guided by real-time 3D TEE&#44; which offered precise spatial location of the perforation and orientation of sheaths and devices&#46; A 20 mm Ultrasept PFO occluder was chosen because &#40;a&#41; it appeared to be the most easily adjustable for the small but asymmetric hole&#44; &#40;b&#41; no residual holes have been reported in these devices&#44; &#40;c&#41; we thought that it would be better to juxtapose two devices with the same type of frame&#44; and &#40;d&#41; it has a low profile&#44; 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Case report
Successful percutaneous closure of a residual atrial septal defect due to device failure
Encerramento percutâneo de comunicação interauricular residual por falência de dispositivo
Sílvia Aguiar Rosaa,
Corresponding author
silviaguiarosa@gmail.com

Corresponding author.
, Filipa Ferreirab, Lídia de Sousaa, António Fiarresgaa, José Diogo Martinsc, Ana Galrinhoa, Ana Agapitoa, Paula Fazendasb, Fátima F. Pintoc, Rui Cruz Ferreiraa
a Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
b Cardiology Department, Garcia de Orta Hospital, Almada, Portugal
c Paediatric Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
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membrane&#46; PVA is a bioabsorbable elastomeric polymer with good biocompatibility that is commonly used in medical devices due to its low protein adsorption&#44; absence of toxicity and bioadhesive characteristics&#46; Although the use of this material in ASD closure devices is generally successful&#44; a few cases of PVA membrane perforation and recanalization have been described recently&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">1&#44;2</span></a> According to company data only 10 cases have been reported&#44; all of them with ASD occluders and none with PFO closure devices&#46; The mechanism by which the PVA coating degrades is not completely understood&#44; but is likely related to incomplete endothelialization due to delayed or inadequate endothelial response&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">3</span></a> This phenomenon has been reported in a few patients with other ASD devices&#44; such as the Amplatzer&#8482; family&#44; supporting the hypothesis of an absent or inadequate endothelization response in specific patients&#44; of unknown cause&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">3&#44;4</span></a> In our patient&#44; there was no evidence of an early residual shunt&#44; but we cannot speculate on the specific causes that may have given rise to this mid-term residual ASD&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">We adopted a percutaneous approach guided by real-time 3D TEE&#44; which offered precise spatial location of the perforation and orientation of sheaths and devices&#46; A 20 mm Ultrasept PFO occluder was chosen because &#40;a&#41; it appeared to be the most easily adjustable for the small but asymmetric hole&#44; &#40;b&#41; no residual holes have been reported in these devices&#44; &#40;c&#41; we thought that it would be better to juxtapose two devices with the same type of frame&#44; and &#40;d&#41; it has a low profile&#44; resulting in a small increase in thickness and no compression of surrounding structures&#44; particularly the aortic wall&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">This case highlights the importance of close follow-up in all patients with ASD treated with implanted devices&#46; There should be a low threshold for TEE in the event of any suspicious findings on TTE or changes in the patient&#39;s clinical status&#46; Our case demonstrates a new and successful way of correcting ASD device perforations with a percutaneous approach that avoids the need for surgical intervention&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Ethical disclosures</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Protection of human and animal subjects</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Confidentiality of data</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Right to privacy and informed consent</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article&#46; The corresponding author is in possession of this document&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Conflicts of interest</span><p id="par0065" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Doente de 39 anos&#44; g&#233;nero feminino&#44; foi submetida com sucesso a encerramento percut&#226;neo de comunica&#231;&#227;o interauricular do tipo <span class="elsevierStyleItalic">ostium secundum</span> com dispositivo <span class="elsevierStyleItalic">Ultrasept Atrial Septal Defect Occluder</span><span class="elsevierStyleSup">&#174;</span> de 22 mm&#46; O ecocardiograma transesof&#225;gico&#44; realizado dois anos ap&#243;s implanta&#231;&#227;o&#44; revelou <span class="elsevierStyleItalic">shunt</span> esquerdo-direito residual de novo atrav&#233;s do dispositivo corretamente implantado&#46; O ecocardiograma transesof&#225;gico tridimensional &#40;ETE3D&#41; objetivou uma perfura&#231;&#227;o do revestimento do dispositivo&#46; A doente foi submetida a encerramento percut&#226;neo do <span class="elsevierStyleItalic">shunt</span> residual com dispositivo <span class="elsevierStyleItalic">UltraSept PFO Occluder</span><span class="elsevierStyleSup">&#174;</span> de 20 mm&#46; O procedimento foi guiado por fluoroscopia e ETE3D&#46; No final do procedimento por ETE3D&#44; foi documentado o correto posicionamento do dispositivo&#44; com completa cobertura da perfura&#231;&#227;o e aus&#234;ncia de <span class="elsevierStyleItalic">shunt</span> residual&#46;</p></span>"
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Revista Portuguesa de Cardiologia (English edition)
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