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Image in Cardiology
Cardiac chondromyxoma
Condromixoma cardíaco
Andreia Fernandesa,
Corresponding author
andreiafvf@gmail.com

Corresponding author.
, Ana Catarina Faustinoa, Lina Carvalhob, Manuel Antunesc, Marco Costaa, Lino Gonçalvesa
a Departamento de Cardiologia, Centro Hospitalar e Universitário de Coimbra, Hospital Geral, Coimbra, Portugal
b Departamento de Patologia Clínica, Centro Hospitalar e Universitário de Coimbra, Hospital Geral, Coimbra, Portugal
c Departamento de Cirúrgica Cardiotorácica, Centro Hospitalar e Universitário de Coimbra, Hospital Geral, Coimbra, Portugal
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          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Transthoracic echocardiogram &#40;modified 4-chamber view&#41; showing a left intraventricular mass measuring 59 mm&#215;35 mm protruding into the left ventricular outflow tract&#44; extending to the pericardium and infiltrating the left ventricular wall&#59; &#40;c and d&#41; computed tomography angiography showing an intracardiac mass occupying the entire left atrium and part of the left ventricle&#44; extending to the pericardium and compressing the inferior vena cava&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The authors present the case of a 68-year-old woman with arterial hypertension&#44; complaining of progressive dyspnea&#44; fatigue&#44; anorexia and weight loss of four months duration&#44; who was referred for a transthoracic echocardiogram to study a cardiac mass diagnosed by computed tomography &#40;CT&#41; angiography &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>&#41;&#46; It was heterogeneous&#44; measuring 63 mm&#215;43 mm&#44; occupying almost the entire left atrium&#44; causing obstruction of blood flow through the mitral valve and extending to the pericardium &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Laboratory tests showed normochromic normocytic anemia&#44; elevated C-reactive protein &#40;23&#46;4 g&#47;dl&#41; and erythrocyte sedimentation rate &#40;57 mm&#47;h&#41;&#46; The electrocardiogram revealed sinus rhythm&#44; with nonspecific repolarization abnormalities&#46; Thoraco-abdominal CT revealed no secondary lesions or adenopathy&#46; Cardiac magnetic resonance imaging was contraindicated&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Partial surgical excision was performed&#46; The tumor was friable and cartilaginous&#44; composed of myxomatous tissue with stellate cells and mature cartilage with foci of atypical cells and inflammatory infiltrate&#44; without mitotic figures&#46; The cells were vimentin positive and CD31&#44; S100 protein and CD68 negative&#46; The final diagnosis was cardiac chondromyxoma with atypical hypercellularity &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The patient was referred to the oncology clinic and maintained in follow-up&#46; Two months later she was readmitted with dyspnea&#46; The tumor had grown&#44; with a left ventricular mass &#40;59 mm&#215;35 mm&#41; protruding into the outflow tract causing obstruction &#40;peak systolic gradient of 54 mmHg&#41;&#44; plus a pericardial mass &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Figure 4</a>&#41;&#46; The patient died suddenly one month later&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">We report a case of a rare type of cardiac mass&#44; with features of both myxoma and chondroma and an extremely malignant behavior&#46; This may be because this variant had a malignant course or&#44; in fact&#44; was not a true myxoma&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Echocardiography and CT in conjunction with the pathological analysis were extremely helpful in establishing the final diagnosis&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical disclosures</span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Protection of human and animal subjects</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Confidentiality of data</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Right to privacy and informed consent</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflicts of interest</span><p id="par0065" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
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Article information
ISSN: 21742049
Original language: English
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Revista Portuguesa de Cardiologia (English edition)
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