Prevalence of dyslipidemia in adolescents: Comparison between definitions | Revista Portuguesa de Cardiologia (English edition)

array:24 ["pii" => "S2174204915000318" "issn" => "21742049" "doi" => "10.1016/j.repce.2014.08.019" "estado" => "S300" "fechaPublicacion" => "2015-02-01" "aid" => "585" "copyright" => "Sociedade Portuguesa de Cardiologia" "copyrightAnyo" => "2014" "documento" => "article" "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Cardiol. 2015;34:103-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4306 "formatos" => array:3 [ "EPUB" => 214 "HTML" => 3350 "PDF" => 742 ] ] "Traduccion" => array:1 [ "en" => array:19 [ "pii" => "S0870255115000050" "issn" => "08702551" "doi" => "10.1016/j.repc.2014.08.020" "estado" => "S300" "fechaPublicacion" => "2015-02-01" "aid" => "585" "copyright" => "Sociedade Portuguesa de Cardiologia" "documento" => "article" "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Cardiol. 2015;34:103-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5026 "formatos" => array:3 [ "EPUB" => 228 "HTML" => 3922 "PDF" => 876 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "Original Article" "titulo" => "Prevalence of dyslipidemia in adolescents: Comparison between definitions" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "pt" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "103" "paginaFinal" => "109" ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Prevalência de dislipidemias em adolescentes: comparação entre diferentes critérios" ] ] "contieneResumen" => array:2 [ "en" => true "pt" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1054 "Ancho" => 1609 "Tamanyo" => 43542 ] ] "descripcion" => array:1 [ "en" => "Prevalence of dyslipidemia in male (n=423) and female (n=577) adolescents, according to the three diagnostic definitions. * p<0.05 vs. (BSC>NCEP=NHANES); † p<0.05 (BSC≠NCEP≠NHANES)." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Crisieli M. Tomeleri, Enio R.V. Ronque, Danilo R.P. Silva, Crivaldo G. Cardoso Júnior, Rômulo A. Fernandes, Denilson C. Teixeira, Décio S. Barbosa, Danielle Venturini, Alessandra M. Okino, Jair A. Oliveira, Edilson S. Cyrino" "autores" => array:11 [ 0 => array:2 [ "nombre" => "Crisieli M." "apellidos" => "Tomeleri" ] 1 => array:2 [ "nombre" => "Enio R.V." "apellidos" => "Ronque" ] 2 => array:2 [ "nombre" => "Danilo R.P." "apellidos" => "Silva" ] 3 => array:2 [ "nombre" => "Crivaldo G." "apellidos" => "Cardoso Júnior" ] 4 => array:2 [ "nombre" => "Rômulo A." "apellidos" => "Fernandes" ] 5 => array:2 [ "nombre" => "Denilson C." "apellidos" => "Teixeira" ] 6 => array:2 [ "nombre" => "Décio S." "apellidos" => "Barbosa" ] 7 => array:2 [ "nombre" => "Danielle" "apellidos" => "Venturini" ] 8 => array:2 [ "nombre" => "Alessandra M." "apellidos" => "Okino" ] 9 => array:2 [ "nombre" => "Jair A." "apellidos" => "Oliveira" ] 10 => array:2 [ "nombre" => "Edilson S." "apellidos" => "Cyrino" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2174204915000318" "doi" => "10.1016/j.repce.2014.08.019" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000318?idApp=UINPBA00004E" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000050?idApp=UINPBA00004E" "url" => "/08702551/0000003400000002/v3_201706020139/S0870255115000050/v3_201706020139/en/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S217420491500032X" "issn" => "21742049" "doi" => "10.1016/j.repce.2014.08.020" "estado" => "S300" "fechaPublicacion" => "2015-02-01" "aid" => "586" "copyright" => "Sociedade Portuguesa de Cardiologia" "documento" => "article" "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Cardiol. 2015;34:111-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3694 "formatos" => array:3 [ "EPUB" => 184 "HTML" => 2869 "PDF" => 641 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "Original Article" "titulo" => "Analysis of lipid-lowering therapy and factors affecting regularity of statin intake in patients with cardiovascular disease enrolled in the PROFILE registry" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "pt" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "111" "paginaFinal" => "116" ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Análise da terapêutica de redução lipídica e dos fatores que afetam a regularidade da toma de estatinas em doentes com doenças cardiovasculares inseridos no Registo Profile" ] ] "contieneResumen" => array:2 [ "en" => true "pt" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1593 "Ancho" => 1578 "Tamanyo" => 149939 ] ] "descripcion" => array:1 [ "en" => "Differences between groups by LDL level. 1: taking statins regularly; 2 not taking statins; 3: taking statins irregularly." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Oleg Gaisenok, Sergey Martsevich, Svetlana Tripkosh, Yulia Lukina" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Oleg" "apellidos" => "Gaisenok" ] 1 => array:2 [ "nombre" => "Sergey" "apellidos" => "Martsevich" ] 2 => array:2 [ "nombre" => "Svetlana" "apellidos" => "Tripkosh" ] 3 => array:2 [ "nombre" => "Yulia" "apellidos" => "Lukina" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0870255115000062" "doi" => "10.1016/j.repc.2014.08.021" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000062?idApp=UINPBA00004E" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217420491500032X?idApp=UINPBA00004E" "url" => "/21742049/0000003400000002/v2_201502270337/S217420491500032X/v2_201502270337/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2174204915000306" "issn" => "21742049" "doi" => "10.1016/j.repce.2014.08.018" "estado" => "S300" "fechaPublicacion" => "2015-02-01" "aid" => "584" "copyright" => "Sociedade Portuguesa de Cardiologia" "documento" => "article" "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Cardiol. 2015;34:95-102" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3900 "formatos" => array:3 [ "EPUB" => 192 "HTML" => 3003 "PDF" => 705 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "Original article" "titulo" => "Continuous infusion or bolus injection of loop diuretics for patients admitted for severe acute heart failure: Is one strategy better than the other?" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "pt" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "95" "paginaFinal" => "102" ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Diuréticos da ansa em doentes com insuficiência cardíaca aguda: perfusão contínua ou bólus – uma estratégia melhor do que a outra?" ] ] "contieneResumen" => array:2 [ "en" => true "pt" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1061 "Ancho" => 2340 "Tamanyo" => 148546 ] ] "descripcion" => array:1 [ "en" => "Evolution of creatinine (in μmol/l) and blood urea nitrogen (in mmol/l) levels during hospitalization in both groups. BUN: blood urea nitrogen; Group A: continuous infusion; Group B: bolus administration." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Francisca Caetano, Paula Mota, Inês Almeida, Andreia Fernandes, Ana Botelho, António Leitão Marques" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Francisca" "apellidos" => "Caetano" ] 1 => array:2 [ "nombre" => "Paula" "apellidos" => "Mota" ] 2 => array:2 [ "nombre" => "Inês" "apellidos" => "Almeida" ] 3 => array:2 [ "nombre" => "Andreia" "apellidos" => "Fernandes" ] 4 => array:2 [ "nombre" => "Ana" "apellidos" => "Botelho" ] 5 => array:2 [ "nombre" => "António" "apellidos" => "Leitão Marques" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0870255115000049" "doi" => "10.1016/j.repc.2014.08.019" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000049?idApp=UINPBA00004E" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000306?idApp=UINPBA00004E" "url" => "/21742049/0000003400000002/v2_201502270337/S2174204915000306/v2_201502270337/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "Original Article" "titulo" => "Prevalence of dyslipidemia in adolescents: Comparison between definitions" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "103" "paginaFinal" => "109" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Crisieli M. Tomeleri, Enio R.V. Ronque, Danilo R.P. Silva, Crivaldo G. Cardoso Júnior, Rômulo A. Fernandes, Denilson C. Teixeira, Décio S. Barbosa, Danielle Venturini, Alessandra M. Okino, Jair A. Oliveira, Edilson S. Cyrino" "autores" => array:11 [ 0 => array:3 [ "nombre" => "Crisieli M." "apellidos" => "Tomeleri" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "Enio R.V." "apellidos" => "Ronque" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] 2 => array:4 [ "nombre" => "Danilo R.P." "apellidos" => "Silva" "email" => array:1 [ 0 => "danilorpsilva@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 3 => array:3 [ "nombre" => "Crivaldo G." "apellidos" => "Cardoso Júnior" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "Rômulo A." "apellidos" => "Fernandes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "b" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "Denilson C." "apellidos" => "Teixeira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] 6 => array:3 [ "nombre" => "Décio S." "apellidos" => "Barbosa" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "c" "identificador" => "aff0015" ] ] ] 7 => array:3 [ "nombre" => "Danielle" "apellidos" => "Venturini" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "c" "identificador" => "aff0015" ] ] ] 8 => array:3 [ "nombre" => "Alessandra M." "apellidos" => "Okino" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "c" "identificador" => "aff0015" ] ] ] 9 => array:3 [ "nombre" => "Jair A." "apellidos" => "Oliveira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "c" "identificador" => "aff0015" ] ] ] 10 => array:3 [ "nombre" => "Edilson S." "apellidos" => "Cyrino" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Study and Research Group in Metabolism, Nutrition, and Exercise GEPEMENE, State University of Londrina – UEL, Londrina, Brazil" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Scientific Research Group Related to Physical Activity (GICRAF), Laboratory of Investigation in Exercise (LIVE), Department of Physical Education, Center of Sciences and Technology, UNESP Univ Estadual Paulista, Presidente Prudente, Brazil" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Department of Pathology, Clinical and Toxicological Analysis, Center of Health Sciences, University Hospital, State University of Londrina – UEL, Londrina, Brazil" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Prevalência de dislipidemias em adolescentes: comparação entre diferentes critérios" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2024 "Ancho" => 1638 "Tamanyo" => 136954 ] ] "descripcion" => array:1 [ "en" => "Prevalence of dyslipidemia subclassifications in male (A) (n=423) and female (B) (n=577) adolescents, according to the three diagnostic definitions. HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TC: total cholesterol; TG: triglycerides. * p<0.05 (BSC≠NCEP≠NHANES); † p<0.05 (BSC=NCEP>NHANES); ‡ p<0.05 (BSC>NCEP=NHANES)." ] ] ] "textoCompleto" => "IntroductionCoronary artery disease is one of the leading causes of death worldwide,<a class="elsevierStyleCrossRefs" href="#bib0195">1,2</a> and dyslipidemia is one of its main risk factors.<a class="elsevierStyleCrossRefs" href="#bib0205">3,4</a> In adolescents, an increase in the prevalence of dyslipidemia has been observed in several studies, especially during the last decade.<a class="elsevierStyleCrossRefs" href="#bib0215">5–11</a> Thus, although it does not usually manifest in children and adolescents, the beginning of the atherosclerotic process may occur early at these stages of life.<a class="elsevierStyleCrossRefs" href="#bib0250">12–14</a>Dyslipidemia is characterized by disorders in lipid metabolism, which lead to changes in the serum levels of circulating lipids and lipoproteins,<a class="elsevierStyleCrossRefs" href="#bib0210">4,15</a> and its subclassifications are established by determining the concentrations of triglycerides (TG), total cholesterol (TC) and its high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) fractions. However, one of the main problems faced by researchers and health care professionals is the indiscriminate use of different criteria for the diagnosis of dyslipidemia, particularly in adolescents.According to the National Cholesterol Education Program (NCEP),<a class="elsevierStyleCrossRef" href="#bib0270">16</a> dyslipidemia is defined as HDL-C <40 mg/dl and TC, LDL-C and TG levels ≥200, ≥130 and ≥130 mg/dl, respectively. This recommendation was adopted as a reference for the Brazilian population until the middle of the last decade, with the support of the Brazilian Society of Cardiology (BSC).<a class="elsevierStyleCrossRef" href="#bib0265">15</a> In 2005, the current NCEP definition was revised by the BSC, which proposed more stringent cutoff points for adolescents.<a class="elsevierStyleCrossRef" href="#bib0275">17</a>However, none of the above cutoff points considered differences between the sexes, which are particularly important regarding the maturation process. A new proposal was therefore presented based on data from the National Health and Nutrition Examination Survey (NHANES), establishing cutoff points for TC, LDL-C, HDL-C and TG levels according to the variables of age and gender: for boys aged 12–16, 223–233 mg/dl for TC, 144–153 mg/dl for LDL-C and 163–195 mg/dl for TG; and for girls, 208–225 mg/dl, 136–145 mg/dl and 158–180 mg/dl for TC, LDL-C and TG, respectively. HDL-C only shows variation in boys, with values 39–46 mg/dl, for the age-group in question.<a class="elsevierStyleCrossRef" href="#bib0280">18</a>Considering the cutoff points recommended by each definition (NCEP, BSC and NHANES), our hypothesis is that the adoption of different criteria may significantly affect the prevalence rates of dyslipidemia, as was observed in recent studies analyzing the impact of the use of different criteria for the classification of metabolic syndrome in Brazilian adolescents.<a class="elsevierStyleCrossRefs" href="#bib0285">19,20</a>We believe that clarifying these issues could be of importance for both researchers and health professionals, helping in the implementation of strategies to prevent and treat dyslipidemia in adolescence. Thus, the aim of the present study was to analyze possible differences in the prevalence rates of dyslipidemia in adolescents of both sexes, based on three diagnostic definitions.MethodsThe present study was based on data from a school-based cross-sectional study on the prevalence of metabolic syndrome and cardiovascular risk factors in adolescents from the city of Londrina, Paraná state, Brazil, carried out during the school year 2011. Sample size was established using an equation based on population parameters,<a class="elsevierStyleCrossRef" href="#bib0295">21</a> which indicated a minimum of 848 subjects, based on the mean prevalence of dyslipidemia of nearly 57% reported in national studies,<a class="elsevierStyleCrossRefs" href="#bib0220">6,7,10,14</a> sample error of 4%, power of 80%, statistical significance of 5% (z=1.96), design effect of 2.0, and increase of 20% to compensate for possible losses and refusals.Participants were selected by a two-stage sampling process. Initially, 55 public schools were listed and grouped according to their geographical location (north, south, east, west, central, and peripheral belt), and two or three schools were then randomly selected in each of these regions. All classes from the 6th to the 9th grades of elementary education were listed, some of which were randomly selected to participate in the study. All students enrolled in the selected classes were invited to participate. Inclusion criteria were: (1) reported good health status (not frequently taking medication or being treated for disease) and (2) return of the consent form duly signed by students and their parents or guardians. Among the 1244 subjects eligible for the study, 1000 adolescents (57.7% female) aged between 11 and 16 years and with complete data on the variables under analysis comprised the study sample. The study was approved by the local research ethics committee (decision 238/2010).Body weight and height were measured according to the procedures described in the literature.<a class="elsevierStyleCrossRef" href="#bib0300">22</a> For determination of lipid profile, 14 ml of venous blood was collected into vacuum tubes with separator gel and without anticoagulant by venous puncture in the antecubital fossa at an adapted classroom in each of the schools, after a 12-hour fast prior to collection. Samples were collected and immediately stored at a temperature of 8°C. After one hour, all samples were centrifuged for 3000 rpm for 15 min and serum aliquots were stored at –70°C until assayed. Subsequently, TG, TC, HDL-C and LDL-C concentrations were determined using a Siemens Dade Behring Dimension RxL Max chemistry analyzer. Dyslipidemia and its subclassifications were diagnosed as abnormal serum levels of circulating lipids and lipoproteins, based on criteria from NCEP, BSC and NHANES.Statistical analysisThe Kolmogorov–Smirnov test was initially used to analyze data distribution. Since the data showed normal distribution, the general characteristics of the sample were expressed as mean and standard deviation. The Kruskal-Wallis test followed by the Mann-Whitney test were used to compare lipid values between ages groups. McNemar's test was applied to compare prevalences between the different definitions of dyslipidemia. The kappa index was used to analyze agreement between the results obtained with the different diagnostic criteria. Statistical significance was set at p<0.05. All analyses were processed using the statistical package SPSS 17.0.This study was partly funded by the Brazilian Council for Scientific and Technological Development (483867/2009-8).ResultsThe general characteristics of the sample stratified by gender are presented in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>.<elsevierMultimedia ident="tbl0005"></elsevierMultimedia>The age- and gender-stratified mean values for lipid profile are presented in <a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>. No significant differences were observed for the different ages in the female group. However, in the male group, adolescents aged 11 years had a mean TC concentration of 172 mg/dl, which was significantly higher than that for age 14 (p<0.05). Furthermore, mean HDL-C was also higher in boys aged 11 years compared to 13 and 15 years (p<0.05).<elsevierMultimedia ident="tbl0010"></elsevierMultimedia><a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a> shows prevalences according to gender. The overall prevalence of dyslipidemia ranged from 24.2% (NHANES) to 61% (BSC). Smaller differences (4.4%) were seen in the comparison between the internationally used definitions (NHANES and NCEP). Significant differences (p<0.05) were observed in the female group with regard to the three definitions, while in the male group differences were limited to comparison between the BSC definition and the other definitions (p<0.05).<elsevierMultimedia ident="fig0005"></elsevierMultimedia>As for dyslipidemia subclassifications (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>), the prevalence rates based on information obtained from the three definitions also varied considerably, regardless of gender, especially those for TC (BSC 38.3%; NCEP 11.2%; NHANES 4.8%) and HDL-C (BSC 30.0%; NCEP 15.8%; NHANES 18.4%). As for LDL-C and TG, the cutoff points for which by BSC and NCEP were similar, the prevalence rates were 10.8% vs. 5.9% (LDL-C) and 4.7% vs. 1.3% (TG) for BSC and NCEP and NHANES, respectively.<elsevierMultimedia ident="fig0010"></elsevierMultimedia><a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a> displays agreement indicators for the different definitions. In general, although relative agreement was higher than 70% in most cases, kappa coefficients showed mostly low to moderate agreement (<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>).<elsevierMultimedia ident="tbl0015"></elsevierMultimedia>DiscussionThe results of this study indicate that the indiscriminate use of different diagnostic criteria for the identification of dyslipidemia and its subclassifications in adolescents may lead to doubtful interpretations. Thus, of the 610 adolescents classified as dyslipidemic by the BSC (61%), only 286 received the same classification by NCEP (28.6%) and 242 by NHANES (24.2%). It should be noted that, in the present sample, the adoption of the international definitions would result in a false negative rate of nearly 35% according to the criteria of the BSC. Therefore, the lack of a single definition with appropriate discriminatory power may compromise both analysis of the prevalence rates of dyslipidemia in this population and decision-making for the implementation of therapeutic or prophylactic interventions.Two previous studies<a class="elsevierStyleCrossRefs" href="#bib0225">7,23</a> analyzed the prevalence of dyslipidemia in a sample of children and adolescents based on the NCEP and BSC definitions. In the first<a class="elsevierStyleCrossRef" href="#bib0305">23</a> the prevalence of dyslipidemia in private and public school students aged 5–16 years was 23% and 4%, respectively (NCEP definition) and 49% and 14%, respectively (BSC definition). In the second study,<a class="elsevierStyleCrossRef" href="#bib0225">7</a> in which the sample consisted of children aged 5–9 years, the differences between the two definitions were smaller, while the prevalence rates were higher (NCEP 64.5% and BSC 68.4%). Thus, similarly to the present study, the BSC definition found a higher prevalence of dyslipidemia than the NCEP definition. However, the differences between the two criteria were greater in the present study, which can be explained at least in part by the different characteristics of the samples analyzed, including sample size, age and maturational status.When analysis of the information obtained in this study was extended to dyslipidemia subclassifications, we found that, regardless of gender, high TC was the most frequent form of dyslipidemia according to the BSC definition, whereas low HDL-C was the predominant anomaly based on the NHANES and NCEP definitions. Of studies that adopted the BSC definition for the diagnosis of dyslipidemia in Brazilian adolescents, this appears to be the first to identify high TC as the predominant form of dyslipidemia, unlike other studies, in which high TG<a class="elsevierStyleCrossRef" href="#bib0310">24</a> and low HDL-C<a class="elsevierStyleCrossRefs" href="#bib0225">7,25–27</a> were the main lipid anomalies.The findings from the present study are of concern, since there is a continuous increase in cardiovascular risk with TC values higher than 180 mg/dl; it is thus important for health prevention that cutoff points remain below this value.<a class="elsevierStyleCrossRef" href="#bib0330">28</a> On this basis, the cutoff points proposed by the BSC definition are perhaps the most appropriate for the diagnosis of dyslipidemia in adolescents.On the other hand, other studies with adolescents based on the NCEP definition found that the predominant forms of dyslipidemia were high TC,<a class="elsevierStyleCrossRefs" href="#bib0330">28,29</a> high TG,<a class="elsevierStyleCrossRefs" href="#bib0205">3,4,9,30,31</a> and low HDL-C.<a class="elsevierStyleCrossRefs" href="#bib0220">6,10,32–34</a> Therefore, depending on the cutoff point adopted and on the specific characteristics of the sample analyzed (socioeconomic level, nutritional status, maturational level, etc.), identification of the predominant form of dyslipidemia can change.Furthermore, since the cutoff points proposed by the NCEP require upgrading<a class="elsevierStyleCrossRef" href="#bib0365">35</a> and changes in lipid levels during adolescence are dependent on age and maturity<a class="elsevierStyleCrossRef" href="#bib0370">36</a> and show wide variations between sexes, the use of fixed cutoff points may be inappropriate in this age-group. In fact, when the mean lipid profile values of adolescents were compared in this study, it was observed that younger boys have higher TC and HDL-C than older boys. However, this was not observed in girls. Our results thus confirmed a gender-based difference.In addition, there appears to be a need for tables with specific cutoff points for each population, since besides the different behavior between the sexes, variables of the lipid profile may be influenced by race and ethnicity.<a class="elsevierStyleCrossRefs" href="#bib0375">37,38</a> Furthermore, when the lipid profile values in this study were compared to the other studies described above,<a class="elsevierStyleCrossRefs" href="#bib0345">31,38</a> we identified differences in TC, with the highest values in Brazilian adolescents aged 11–15 years of both sexes. On the other hand, mean TG values were lower than those described by Yang et al.<a class="elsevierStyleCrossRef" href="#bib0345">31</a> at all ages analyzed.Considering that therapeutic or prophylactic measures should be implemented based on the categorization identified by the criteria adopted, inaccurate diagnosis can result in ineffective strategies. For example, in cases or populations in which low HDL-C is found as the predominant dyslipidemic subclass, increases in levels of physical activity and engagement in exercise programs may play a more important role than the adoption of other strategies for controlling other lipid alterations.Some important limitations of the present study should be pointed out, such as the lack of a gold standard for comparison between the different criteria, which would be essential for sensitivity and specificity analysis. Moreover, there was no control for the maturational process, which could have provided valuable information for better stratification of the sample and extrapolation of the results. Additionally, although this is a school-based population study, generalization of the results is limited by the impact of the socioeconomic and cultural context on the behavior of the variables analyzed. Finally, the criteria analyzed were established on the basis of characteristics of other populations, at a different time, which also reduces the ecological validity of the present investigation.In conclusion, the dyslipidemia prevalence rates found in adolescents of both genders in the present study were very high, despite the differences in the estimates obtained by the different definitions analyzed. The BSC definition, with its more stringent cutoff points, was the one that detected the highest rates, regardless of gender and the different dyslipidemia subclassifications. Finally, the results of the present study suggest that the indiscriminate use of different diagnostic criteria to estimate the prevalence of dyslipidemia in adolescents may result in inaccurate interpretations, which could compromise diagnosis and therefore the therapeutic and prophylactic measures to be taken.Ethical disclosuresProtection of human and animal subjectsThe authors declare that the procedures followed were in accordance with the regulations of the relevant clinical research ethics committee and with those of the Code of Ethics of the World Medical Association (Declaration of Helsinki).Confidentiality of dataThe authors declare that they have followed the protocols of their work center on the publication of patient data.Right to privacy and informed consentThe authors have obtained the written informed consent of the patients or subjects mentioned in the article. The corresponding author is in possession of this document.Conflicts of interestThe authors have no conflicts of interest to declare." "textoCompletoSecciones" => array:1 [ "secciones" => array:12 [ 0 => array:3 [ "identificador" => "xres439420" "titulo" => "Abstract" "secciones" => array:5 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Introduction" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Objective" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Methods" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Results" ] 4 => array:2 [ "identificador" => "abst0025" "titulo" => "Conclusions" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec462609" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres439419" "titulo" => "Resumo" "secciones" => array:5 [ 0 => array:2 [ "identificador" => "abst0030" "titulo" => "Fundamento" ] 1 => array:2 [ "identificador" => "abst0035" "titulo" => "Objetivo" ] 2 => array:2 [ "identificador" => "abst0040" "titulo" => "Métodos" ] 3 => array:2 [ "identificador" => "abst0045" "titulo" => "Resultados" ] 4 => array:2 [ "identificador" => "abst0050" "titulo" => "Conclusões" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec462608" "titulo" => "Palavras-chave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:3 [ "identificador" => "sec0010" "titulo" => "Methods" "secciones" => array:1 [ 0 => array:2 [ "identificador" => "sec0015" "titulo" => "Statistical analysis" ] ] ] 6 => array:2 [ "identificador" => "sec0020" "titulo" => "Results" ] 7 => array:2 [ "identificador" => "sec0025" "titulo" => "Discussion" ] 8 => array:3 [ "identificador" => "sec0030" "titulo" => "Ethical disclosures" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0035" "titulo" => "Protection of human and animal subjects" ] 1 => array:2 [ "identificador" => "sec0040" "titulo" => "Confidentiality of data" ] 2 => array:2 [ "identificador" => "sec0045" "titulo" => "Right to privacy and informed consent" ] ] ] 9 => array:2 [ "identificador" => "sec0050" "titulo" => "Conflicts of interest" ] 10 => array:2 [ "identificador" => "xack131767" "titulo" => "Acknowledgments" ] 11 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2014-02-24" "fechaAceptado" => "2014-08-16" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec462609" "palabras" => array:4 [ 0 => "Risk factors" 1 => "Cardiovascular disease" 2 => "Atherosclerosis" 3 => "Youth" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec462608" "palabras" => array:4 [ 0 => "Fatores de risco" 1 => "Doenças cardiovasculares" 2 => "Aterosclerose" 3 => "Jovens" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:3 [ "titulo" => "Abstract" "resumen" => "IntroductionThe indiscriminate use of different diagnostic criteria for the definition of dyslipidemia may result in inaccurate interpretations, which could compromise diagnosis and therefore the therapeutic and prophylactic actions to be taken. ObjectiveTo analyze possible differences in prevalence rates of dyslipidemia in adolescents based on three diagnostic definitions. MethodsA cross-sectional study was conducted of a representative sample of Brazilian adolescents between 11 and 16 years of age. Blood samples were collected from 1000 students (423 boys and 577 girls) to determine fasting total cholesterol (TC), HDL and LDL cholesterol, and triglycerides (TG). The prevalence of dyslipidemia was established according to three definitions: those of the National Cholesterol Education Program (NCEP), the Brazilian Society of Cardiology (BSC), and the National Health and Nutrition Examination Survey (NHANES). ResultsSignificant differences (p<0.01) were found between the diagnostic criteria for TC (BSC 38.3%; NCEP 11.2%; NHANES 4.8%), HDL cholesterol (BSC 30.0%; NCEP 15.8% NHANES 18.4%), LDL cholesterol (BSC and NCEP 10.8% and NHANES 5.9%), and TG (BSC and NCEP 4.7% and NHANES 1.3%). The overall prevalence of dyslipidemia was 61% (BSC), 28.6% (NCEP) and 24.2% (NHANES). Agreement rates varied significantly (kappa 0.15–0.90). ConclusionsAlthough a high prevalence of dyslipidemia was observed in this study regardless of the diagnostic criteria used, the wide variation in rates highlights the need to establish a single definition with appropriate discriminatory power for adolescents." "secciones" => array:5 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Introduction" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Objective" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Methods" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Results" ] 4 => array:2 [ "identificador" => "abst0025" "titulo" => "Conclusions" ] ] ] "pt" => array:3 [ "titulo" => "Resumo" "resumen" => "FundamentoO uso indiscriminado de diferentes critérios diagnósticos para a determinação de dislipidemias pode resultar em interpretações imprecisas, podendo comprometer o diagnóstico e, consequentemente, as ações terapêuticas e profiláticas a serem empregadas. ObjetivoAnalisar possíveis diferenças nas taxas de prevalência de dislipidemias em adolescentes, com base em três critérios diagnósticos. MétodosEstudo transversal conduzido com uma amostra representativa de adolescentes brasileiros de 11 a 16 anos. Amostras de sangue foram coletadas de 1000 escolares (423 rapazes e 577 moças) para determinação do colesterol total (CT), HDL, LDL e triglicérides (TG) em jejum. A prevalência de dislipidemias foi estabelecida com base em três critérios diagnósticos: National Cholesterol Education Program (NCEP), Sociedade Brasileira de Cardiologia (SBC) e National Health and Nutrition Examination Survey (NHANES). ResultadosDiferenças significantes (p<0,01) foram identificadas entre os critérios diagnósticos analisados para CT (SBC=38,3%; NCEP=11,2%; NHANES=4,8%), HDL (SBC=30,0%; NCEP=15,8%; NHANES=18,4%), LDL (SBC/NCEP=10,8% e NHANES=5,9%) e TG (SBC/NCEP=4,7% e NHANES=1,3%). No geral, a prevalência de dislipidemias foi na ordem de 61% (SBC); 28,6% (NCEP) e 24,2% (NHANES). Os índices de concordância variaram amplamente (Kappa=0,15 a 0,90). ConclusõesEmbora uma elevada prevalência de dislipidemias tenha sido identificada neste estudo, independente dos critérios diagnósticos utilizados, a ampla variação nas taxas encontradas reforça a necessidade do estabelecimento de um critério único e com poder de discriminação adequado para adolescentes." "secciones" => array:5 [ 0 => array:2 [ "identificador" => "abst0030" "titulo" => "Fundamento" ] 1 => array:2 [ "identificador" => "abst0035" "titulo" => "Objetivo" ] 2 => array:2 [ "identificador" => "abst0040" "titulo" => "Métodos" ] 3 => array:2 [ "identificador" => "abst0045" "titulo" => "Resultados" ] 4 => array:2 [ "identificador" => "abst0050" "titulo" => "Conclusões" ] ] ] ] "multimedia" => array:5 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1046 "Ancho" => 1601 "Tamanyo" => 74699 ] ] "descripcion" => array:1 [ "en" => "Prevalence of dyslipidemia in male (n=423) and female (n=577) adolescents, according to the three diagnostic definitions. * p<0.05 vs. (BSC>NCEP=NHANES); † p<0.05 (BSC≠NCEP≠NHANES)." ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2024 "Ancho" => 1638 "Tamanyo" => 136954 ] ] "descripcion" => array:1 [ "en" => "Prevalence of dyslipidemia subclassifications in male (A) (n=423) and female (B) (n=577) adolescents, according to the three diagnostic definitions. HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TC: total cholesterol; TG: triglycerides. * p<0.05 (BSC≠NCEP≠NHANES); † p<0.05 (BSC=NCEP>NHANES); ‡ p<0.05 (BSC>NCEP=NHANES)." ] ] 2 => array:7 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "leyenda" => "BMI: body mass index; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TC: total cholesterol; TG: triglycerides." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="" valign="top" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Boys (n=423) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Girls (n=577) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Total (n=1000) \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">Age (years) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">13.1±1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">12.8±1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">12.9±1 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">Weight (kg) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">48.7±14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">47.5±12 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">48.0±13 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">Height (m) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">155.9±11 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">154.0±8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">154.8±10 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BMI (kg/m2) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">19.8±4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">19.9±4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">19.8±4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">TC (mg/dl) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">163±28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">165±28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">164±28 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">LDL-C (mg/dl) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">99±24 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">99±25 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">99±25 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">HDL-C (mg/dl) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">52±14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">52±13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">52±13 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">TG (mg/dl) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">61±34 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">66±35 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">64±34 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab685939.png" ] ] ] ] "descripcion" => array:1 [ "en" => "General characteristics of the sample according to gender." ] ] 3 => array:7 [ "identificador" => "tbl0010" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:3 [ "leyenda" => "LDL-C: low-density lipoprotein cholesterol; HDL: high-density lipoprotein cholesterol; TC: total cholesterol; TG: triglycerides." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="left" valign="top" scope="col">Age \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="" valign="top" scope="col"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " colspan="4" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Boys</th><th class="td" title="table-head " align="" valign="top" scope="col"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " colspan="4" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Girls</th></tr><tr title="table-row"><th class="td" title="table-head " align="" valign="top" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">n \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">TC \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">LDL-C \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">HDL \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">TG \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">n \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">TC \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">LDL-C \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">HDL \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">TG \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry " align="char" valign="top">11 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">69 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">172±28<a class="elsevierStyleCrossRef" href="#tblfn0005">a</a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">102±24<a class="elsevierStyleCrossRef" href="#tblfn0015">c</a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">57±15<a class="elsevierStyleCrossRef" href="#tblfn0010">b</a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">62±32 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">117 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">169±27 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">104±24 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">51±13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">67±31 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="char" valign="top">12 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">97 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">166±25<a class="elsevierStyleCrossRef" href="#tblfn0005">a</a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">101±24 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">53±14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">58±35 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">149 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">165±26 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">98±26 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">53±14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">68±45 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="char" valign="top">13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">87 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">167±26<a class="elsevierStyleCrossRef" href="#tblfn0005">a</a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">103±23<a class="elsevierStyleCrossRef" href="#tblfn0025">e</a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">50±12 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">68±37 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">127 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">163±26 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">97±22 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">54±13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">62±28 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="char" valign="top">14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">102 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">158±28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">95±24 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">51±13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">59±28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">128 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">165±28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">99±28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">53±11 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">68±32 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="char" valign="top">15 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">48 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">155±32 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">97±29 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">45±11<a class="elsevierStyleCrossRef" href="#tblfn0020">d</a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">62±35 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">41 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">158±31 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">96±21 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">49±9 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">68±26 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="char" valign="top">16 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">20 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">150±21 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">90±19 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">49±17 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">55±28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">15 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">152±21 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">93±20 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">47±13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">63±26 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab685937.png" ] ] ] "notaPie" => array:5 [ 0 => array:3 [ "identificador" => "tblfn0005" "etiqueta" => "a" "nota" => "p<0.05 vs. 14, 15 and 16 age-group." ] 1 => array:3 [ "identificador" => "tblfn0010" "etiqueta" => "b" "nota" => "p<0.05 vs. 13, 14, 15 and 16 age-group." ] 2 => array:3 [ "identificador" => "tblfn0015" "etiqueta" => "c" "nota" => "p<0.05 vs. 16 age-group." ] 3 => array:3 [ "identificador" => "tblfn0020" "etiqueta" => "d" "nota" => "p<0.05 vs. 12, 13 and 14 age-group." ] 4 => array:3 [ "identificador" => "tblfn0025" "etiqueta" => "e" "nota" => "p<0.05 vs. 14 and 16 age-group." ] ] ] "descripcion" => array:1 [ "en" => "Mean values and standard deviations of total cholesterol, LDL cholesterol, HDL cholesterol and triglycerides according to age and gender." ] ] 4 => array:7 [ "identificador" => "tbl0015" "etiqueta" => "Table 3" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "leyenda" => "All kappa coefficients were significant (p<0.01). BSC: Brazilian Society of Cardiology; CI: confidence interval; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; NCEP: National Cholesterol Education Program; NHANES: National Health and Nutrition Examination Survey; TC: total cholesterol; TG: triglycerides." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="" valign="top" scope="col"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Boys (n=423)</th><th class="td" title="table-head " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Girls (n=577)</th><th class="td" title="table-head " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Total (n=1000)</th></tr><tr title="table-row"><th class="td" title="table-head " align="" valign="top" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Kappa (95% CI) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">% \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Kappa (95% CI) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">% \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Kappa (95% CI) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">% \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry " colspan="7" align="left" valign="top">TC</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BSC vs. NCEP \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.34 (0.26–0.42) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">74.0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.34 (0.27–0.40) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">72.1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.34 (0.29–0.39) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">72.9 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BSC vs. NHANES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.10 (0.05–0.15) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">66.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.18 (0.13–0.24) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">66.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.15 (0.11–0.19) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">66.5 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">NCEP vs. NHANES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.40 (0.24–0.56) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">92.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.67 (0.56–0.77) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">94.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.57 (0.48–0.66) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">93.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="7" align="left" valign="top"></td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="7" align="left" valign="top">LDL-C</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BSC vs. NCEP \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">100 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">100 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">100 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BSC vs. NHANES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.49 (0.33–0.65) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">93.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.79 (0.70–0.88) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">96.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.68 (0.60–0.77) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">95.1 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">NCEP vs. NHANES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.49 (0.33–0.65) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">93.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.79 (0.70–0.88) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">96.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.68 (0.60–0.77) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">95.1 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="7" align="left" valign="top"></td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="7" align="left" valign="top">HDL-C</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BSC vs. NCEP \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.59 (0.51–0.66) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">83.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.62 (0.54–0.70) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">87.7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.61 (0.55–0.66) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">85.8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BSC vs. NHANES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.75 (0.68–0.82) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">89.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.62 (0.55–0.70) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">87.7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.69 (0.64–0.74) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">88.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">NCEP vs. NHANES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.82 (0.74–0.88) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">93.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">100 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.90 (0.87–0.94) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">97.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="7" align="left" valign="top"></td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="7" align="left" valign="top">TG</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BSC vs. NCEP \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">100 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">100 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">100 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">BSC vs. NHANES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.39 (0.17–0.61) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">95.7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.46 (0.24–0.68) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">97.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.42 (0.27–0.58) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">96.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="left" valign="top">NCEP vs. NHANES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.39 (0.17–0.61) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">95.7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.46 (0.24–0.68) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">97.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.42 (0.27–0.58) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">96.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab685938.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Analysis of agreement between the three diagnostic definitions used to assess the prevalence of dyslipidemia in adolescents." ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:38 [ 0 => array:3 [ "identificador" => "bib0195" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pathobiological determinants of atherosclerosis in youth risk scores are associated with early and advanced atherosclerosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "C.A. McMahan" 1 => "S.S. Gidding" 2 => "G.T. Malcon" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1542/peds.2006-0970" "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2006" "volumen" => "118" "paginaInicial" => "1447" "paginaFinal" => "1455" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17015535" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0200" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preventing chronic diseases: a vital investment" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "World Health Organization" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "2005" "editorial" => "World Health Organization" "editorialLocalizacion" => "Switzerland" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0205" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lípides e lipoproteinas séricos em crianças e adolescentes de um hospital universitário público" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E.C. Faria" 1 => "F.B. Dalpino" 2 => "R. Takata" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Paul Pediatr" "fecha" => "2008" "volumen" => "26" "paginaInicial" => "54" "paginaFinal" => "58" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0210" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dislipidemias na infância e adolescência" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "I.C.B. Giuliano" 1 => "B. Caramelli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pediatria" "fecha" => "2008" "volumen" => "29" "paginaInicial" => "275" "paginaFinal" => "285" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0215" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Associated factors to total cholesterol: school based study in Southern Brazil" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "M.L.A. Bergmann" 1 => "G.G. Bergmann" 2 => "R. Halpern" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "2011" "volumen" => "97" "paginaInicial" => "17" "paginaFinal" => "25" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21625818" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0220" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Perfil lipídico e estado nutricional de adolescentes" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "D.F. Carvalho" 1 => "A.A. Paiva" 2 => "A.S.O. Melo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Bras Epidemiol" "fecha" => "2007" "volumen" => "10" "paginaInicial" => "491" "paginaFinal" => "498" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0225" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalência em crianças de fatores de risco para as doenças cardiovasculares" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.S. Gama" 1 => "M.S. Carvalho" 2 => "C.R.M. Chaves" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cad Saúde Pública" "fecha" => "2007" "volumen" => "23" "paginaInicial" => "2239" "paginaFinal" => "2245" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17700959" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0230" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Serum lipids in school kids and adolescents from Florianópolis, SC, Brazil – Healthy Floripa 2040 Study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "I.C.B. Giuliano" 1 => "M.S.S.A. Coutinho" 2 => "S.F.T. Freitas" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "/S0066-782X2005001400003" "Revista" => array:6 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "2005" "volumen" => "85" "paginaInicial" => "85" "paginaFinal" => "91" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16113845" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0235" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of pediatric dyslipidemia: comparison of a population-based claims database to national surveys" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "J. Li" 1 => "S.P. Motsko" 2 => "E.L. Goehring Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/pds.1982" "Revista" => array:6 [ "tituloSerie" => "Pharmacoepidemiol Drug Saf" "fecha" => "2010" "volumen" => "19" "paginaInicial" => "1031" "paginaFinal" => "1040" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20602343" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0240" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dyslipidemia in schoolchildren from private schools in Belém" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.S. Ribas" 1 => "L.C.S. Silva" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "2009" "volumen" => "92" "paginaInicial" => "446" "paginaFinal" => "451" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0245" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lipid and lipoprotein profiles and prevalence of dyslipidemia in Mexican adolescents" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "R.P. Sánchez" 1 => "C.P. Romero" 2 => "J.Z. González" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.metabol.2007.07.009" "Revista" => array:6 [ "tituloSerie" => "Metabolism" "fecha" => "2007" "volumen" => "56" "paginaInicial" => "1666" "paginaFinal" => "1672" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17998019" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0250" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "In utero programming of cardiovascular disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.J. Barker" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Theriogenology" "fecha" => "2000" "volumen" => "53" "paginaInicial" => "555" "paginaFinal" => "574" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10735050" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0255" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "G.S. Berenson" 1 => "S.R. Srinivasan" 2 => "W. Bao" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199806043382302" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1998" "volumen" => "338" "paginaInicial" => "1650" "paginaFinal" => "1656" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9614255" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0260" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk factors for atherosclerosis in children and adolescents with family history of premature coronary artery disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "C.C. Romaldini" 1 => "H. Issler" 2 => "A.L. Cardoso" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Pediatr (Rio J)" "fecha" => "2004" "volumen" => "80" "paginaInicial" => "135" "paginaFinal" => "140" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0265" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "III Diretrizes Brasileiras sobre Dislipidemias e Diretriz de Prevenção da Aterosclerose do Departamento de Aterosclerose" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Sociedade Brasileira de Cardiologia (BSC)" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "2001" "volumen" => "77" "numero" => "supl. 1" "paginaInicial" => "1" "paginaFinal" => "48" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11781591" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0270" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2002" "volumen" => "106" "paginaInicial" => "3143" "paginaFinal" => "3421" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12485966" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0275" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "I guidelines for prevention of atherosclerosis in childhood and adolescence" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Brazilian Society of Cardiology (BSC)" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "/S0066-782X2005001300002" "Revista" => array:6 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "2005" "volumen" => "85" "paginaInicial" => "3" "paginaFinal" => "36" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16041447" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0280" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Distribution of lipoproteins by age and gender in adolescents" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.J. Jolliffe" 1 => "I. Janssen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/CIRCULATIONAHA.106.620864" "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2006" "volumen" => "114" "paginaInicial" => "1056" "paginaFinal" => "1062" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16940191" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0285" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metabolic syndrome: comparison of diagnosis criteria" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "M.L. Cavali" 1 => "M.A. Escrivão" 2 => "R.S. Brasileiro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Pediatr (Rio J)" "fecha" => "2010" "volumen" => "86" "paginaInicial" => "325" "paginaFinal" => "330" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0290" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metabolic syndrome in obese adolescents: a comparison of three different diagnostic criteria" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "R.F. Costa" 1 => "N.S. Santos" 2 => "N.P. Goldraich" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Pediatr (Rio J)" "fecha" => "2012" "volumen" => "88" "paginaInicial" => "303" "paginaFinal" => "309" ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0295" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A lógica da determinação do tamanho da amostra em investigações epidemiológicas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.R. Luiz" 1 => "M.M.F. Magnanini" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cad Saúde Colet" "fecha" => "2000" "volumen" => "8" "paginaInicial" => "9" "paginaFinal" => "28" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0300" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stature, recumbent length, and weight" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.C. Gordon" 1 => "W.C. Chumlea" 2 => "A.F. Roche" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Anthropometric standardizing reference manual" "paginaInicial" => "3" "paginaFinal" => "8" "serieFecha" => "1988" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0305" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lipid profile analysis in school children" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Scherr" 1 => "C.K. Magalhães" 2 => "W. Malheiros" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "2007" "volumen" => "89" "paginaInicial" => "73" "paginaFinal" => "78" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0310" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dyslipidemia among adolescents and children from Pernambuco" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Franca" 1 => "J.G.B. Alves" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "2006" "volumen" => "87" "paginaInicial" => "722" "paginaFinal" => "727" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17262109" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0315" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Avaliação do perfil lipídico em alunos de 10 a 18 anos em uma escola particular do município de Carazinho-RS" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.L. Kerber" 1 => "A.G.U. Antunes" 2 => "C. Cavalette" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Bras Anal Clin" "fecha" => "2010" "volumen" => "42" "paginaInicial" => "231" "paginaFinal" => "234" ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0320" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Association between dyslipidemia and anthropometric indicators in adolescents" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "S.C. Vieira Cunha Lima" 1 => "C. Oliveira Lyra" 2 => "L. Galvão Bacurau Pinheiro" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1590/S0212-16112011000200010" "Revista" => array:6 [ "tituloSerie" => "Nutr Hosp" "fecha" => "2011" "volumen" => "26" "paginaInicial" => "304" "paginaFinal" => "310" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21666967" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0325" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lipid profile of schoolchildren from Recife – PE" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "P.B. Pereira" 1 => "I.K.G. Arruda" 2 => "A.M.T.S. Cavalcanti" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "2010" "volumen" => "95" "paginaInicial" => "606" "paginaFinal" => "613" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20944894" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0330" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fatores de risco de aterosclerose na infância. Um estudo epidemiológico" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Z.R.S. Gerber" 1 => "P. Zielinsky" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arq Bras Cardiol" "fecha" => "1997" "volumen" => "69" "paginaInicial" => "231" "paginaFinal" => "236" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9595714" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0335" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of dyslipidemia in non-obese prepubertal children and its association with family history of diabetes, high blood pressure, and obesity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F. Guerrero-Romero" 1 => "Rodrigues-Morán" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.arcmed.2006.06.003" "Revista" => array:6 [ "tituloSerie" => "Arch Med Res" "fecha" => "2006" "volumen" => "37" "paginaInicial" => "1015" "paginaFinal" => "1021" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17045120" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0340" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Colesterolemia, trigliceridemia e excesso de peso em escolares de Santa Maria, RS, Brasil" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.C. Lunardi" 1 => "C.M. Moreira" 2 => "D.L. Santos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Bras Med Esporte" "fecha" => "2010" "volumen" => "16" "paginaInicial" => "250" "paginaFinal" => "253" ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0345" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Serum lipid concentrations, prevalence of dyslipidemia and percentage eligible for pharmacological treatment of Korean children and adolescents; data from the Korea National Health and Nutrition Examination Survey IV (2007–2009)" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "S. Yang" 1 => "J.S. Hwang" 2 => "H.K. Park" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1371/journal.pone.0049253" "Revista" => array:5 [ "tituloSerie" => "PLoS ONE" "fecha" => "2012" "volumen" => "7" "paginaInicial" => "e49253" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23251338" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0350" "etiqueta" => "32" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Perfil lipídico e obesidade em escolares de baixa renda" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "L.P. Grillo" 1 => "S.P. Crispim" 2 => "N.A. Siebert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Bras Epidemiol" "fecha" => "2005" "volumen" => "8" "paginaInicial" => "75" "paginaFinal" => "78" ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0355" "etiqueta" => "33" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Trends in serum lipids among US youths aged 6 to 19 years, 1988–2010" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "B.K. Kit" 1 => "M.D. Carroll" 2 => "D.A. Lacher" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/jama.2012.9136" "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "2012" "volumen" => "308" "paginaInicial" => "591" "paginaFinal" => "600" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22871871" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0360" "etiqueta" => "34" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lipid profiles and prevalence of dyslipidemia in schoolchildren in south Khorasan Province, Eastern Iran" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Fesharakinia" 1 => "A. Zarban" 2 => "G.R. Sharifzadeh" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Iran Med" "fecha" => "2008" "volumen" => "11" "paginaInicial" => "598" "paginaFinal" => "601" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18976028" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib0365" "etiqueta" => "35" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New cholesterol guidelines for children?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.S. Gidding" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/CIRCULATIONAHA.106.647891" "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2006" "volumen" => "114" "paginaInicial" => "989" "paginaFinal" => "991" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16952994" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib0370" "etiqueta" => "36" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sensitivity and specificity of pediatric lipid determinations for adult lipid status: findings from the Princeton Lipid Research Clinics Prevalence Program Follow-up Study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "L.A. Friedman" 1 => "J.A. Morrison" 2 => "S.R. Daniels" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1542/peds.2005-2968" "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2006" "volumen" => "118" "paginaInicial" => "165" "paginaFinal" => "172" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16818562" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib0375" "etiqueta" => "37" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Worldwide distribution of blood lipids and lipoproteins in childhood and adolescence: a review study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Brotons" 1 => "A. Ribeira" 2 => "R.M. Perich" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Atherosclerosis" "fecha" => "1998" "volumen" => "139" "paginaInicial" => "1" "paginaFinal" => "9" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9699886" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib0380" "etiqueta" => "38" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Concentrations of low-density lipoprotein cholesterol and total cholesterol among children and adolescents in the United States" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "E.S. Ford" 1 => "C. Li" 2 => "G. Zhao" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/CIRCULATIONAHA.108.816769" "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2009" "volumen" => "119" "paginaInicial" => "1108" "paginaFinal" => "1115" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19221218" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] "agradecimientos" => array:1 [ 0 => array:4 [ "identificador" => "xack131767" "titulo" => "Acknowledgments" "texto" => "We would like to thank the participants who voluntarily contributed to this study, the Local Education Authority of the city of Londrina, Brazil, and the 10 public schools which made this entire project possible. This study was supported (Process 483867/2009-8) by the Council for Scientific and Technological Development (CNPq/Brazil). The authors E.R.V.R. and D.P.R.S. were supported by the CNPq and E.S.C. was supported by the Coordination of Improvement of Higher Education Personnel (CAPES/Brazil)." "vista" => "all" ] ] ] "idiomaDefecto" => "en" "url" => "/21742049/0000003400000002/v2_201502270337/S2174204915000318/v2_201502270337/en/main.assets" "Apartado" => array:4 [ "identificador" => "9912" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Original article" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21742049/0000003400000002/v2_201502270337/S2174204915000318/v2_201502270337/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000318?idApp=UINPBA00004E"]

Statistics

Original Article

Prevalence of dyslipidemia in adolescents: Comparison between definitions

Prevalência de dislipidemias em adolescentes: comparação entre diferentes critérios

Crisieli M. Tomeleria, Enio R.V. Ronquea, Danilo R.P. Silvaa,

Corresponding author

danilorpsilva@gmail.com

Corresponding author.

, Crivaldo G. Cardoso Júniora, Rômulo A. Fernandesb, Denilson C. Teixeiraa, Décio S. Barbosac, Danielle Venturinic, Alessandra M. Okinoc, Jair A. Oliveirac, Edilson S. Cyrinoa

a Study and Research Group in Metabolism, Nutrition, and Exercise GEPEMENE, State University of Londrina – UEL, Londrina, Brazil

b Scientific Research Group Related to Physical Activity (GICRAF), Laboratory of Investigation in Exercise (LIVE), Department of Physical Education, Center of Sciences and Technology, UNESP Univ Estadual Paulista, Presidente Prudente, Brazil

c Department of Pathology, Clinical and Toxicological Analysis, Center of Health Sciences, University Hospital, State University of Londrina – UEL, Londrina, Brazil

Read

7170

Times
was read the article

1936

Total PDF

5234

Total HTML

Share statistics

 array:24 [
  "pii" => "S2174204915000318"
  "issn" => "21742049"
  "doi" => "10.1016/j.repce.2014.08.019"
  "estado" => "S300"
  "fechaPublicacion" => "2015-02-01"
  "aid" => "585"
  "copyright" => "Sociedade Portuguesa de Cardiologia"
  "copyrightAnyo" => "2014"
  "documento" => "article"
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "fla"
  "cita" => "Rev Port Cardiol. 2015;34:103-9"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4306
    "formatos" => array:3 [
      "EPUB" => 214
      "HTML" => 3350
      "PDF" => 742
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:19 [
      "pii" => "S0870255115000050"
      "issn" => "08702551"
      "doi" => "10.1016/j.repc.2014.08.020"
      "estado" => "S300"
      "fechaPublicacion" => "2015-02-01"
      "aid" => "585"
      "copyright" => "Sociedade Portuguesa de Cardiologia"
      "documento" => "article"
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Rev Port Cardiol. 2015;34:103-9"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 5026
        "formatos" => array:3 [
          "EPUB" => 228
          "HTML" => 3922
          "PDF" => 876
        ]
      ]
      "en" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
        "titulo" => "Prevalence of dyslipidemia in adolescents&#58; Comparison between definitions"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "tieneResumen" => array:2 [
          0 => "en"
          1 => "pt"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "103"
            "paginaFinal" => "109"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Preval&#234;ncia de dislipidemias em adolescentes&#58; compara&#231;&#227;o entre diferentes crit&#233;rios"
          ]
        ]
        "contieneResumen" => array:2 [
          "en" => true
          "pt" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figure 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1054
                "Ancho" => 1609
                "Tamanyo" => 43542
              ]
            ]
            "descripcion" => array:1 [
              "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Prevalence of dyslipidemia in male &#40;n&#61;423&#41; and female &#40;n&#61;577&#41; adolescents&#44; according to the three diagnostic definitions&#46; &#42; p&#60;0&#46;05 vs&#46; &#40;BSC&#62;NCEP&#61;NHANES&#41;&#59; &#8224; p&#60;0&#46;05 &#40;BSC&#8800;NCEP&#8800;NHANES&#41;&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Crisieli M&#46; Tomeleri, Enio R&#46;V&#46; Ronque, Danilo R&#46;P&#46; Silva, Crivaldo G&#46; Cardoso J&#250;nior, R&#244;mulo A&#46; Fernandes, Denilson C&#46; Teixeira, D&#233;cio S&#46; Barbosa, Danielle Venturini, Alessandra M&#46; Okino, Jair A&#46; Oliveira, Edilson S&#46; Cyrino"
            "autores" => array:11 [
              0 => array:2 [
                "nombre" => "Crisieli M&#46;"
                "apellidos" => "Tomeleri"
              ]
              1 => array:2 [
                "nombre" => "Enio R&#46;V&#46;"
                "apellidos" => "Ronque"
              ]
              2 => array:2 [
                "nombre" => "Danilo R&#46;P&#46;"
                "apellidos" => "Silva"
              ]
              3 => array:2 [
                "nombre" => "Crivaldo G&#46;"
                "apellidos" => "Cardoso J&#250;nior"
              ]
              4 => array:2 [
                "nombre" => "R&#244;mulo A&#46;"
                "apellidos" => "Fernandes"
              ]
              5 => array:2 [
                "nombre" => "Denilson C&#46;"
                "apellidos" => "Teixeira"
              ]
              6 => array:2 [
                "nombre" => "D&#233;cio S&#46;"
                "apellidos" => "Barbosa"
              ]
              7 => array:2 [
                "nombre" => "Danielle"
                "apellidos" => "Venturini"
              ]
              8 => array:2 [
                "nombre" => "Alessandra M&#46;"
                "apellidos" => "Okino"
              ]
              9 => array:2 [
                "nombre" => "Jair A&#46;"
                "apellidos" => "Oliveira"
              ]
              10 => array:2 [
                "nombre" => "Edilson S&#46;"
                "apellidos" => "Cyrino"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2174204915000318"
          "doi" => "10.1016/j.repce.2014.08.019"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000318?idApp=UINPBA00004E"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000050?idApp=UINPBA00004E"
      "url" => "/08702551/0000003400000002/v3_201706020139/S0870255115000050/v3_201706020139/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S217420491500032X"
    "issn" => "21742049"
    "doi" => "10.1016/j.repce.2014.08.020"
    "estado" => "S300"
    "fechaPublicacion" => "2015-02-01"
    "aid" => "586"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Cardiol. 2015;34:111-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3694
      "formatos" => array:3 [
        "EPUB" => 184
        "HTML" => 2869
        "PDF" => 641
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Analysis of lipid-lowering therapy and factors affecting regularity of statin intake in patients with cardiovascular disease enrolled in the PROFILE registry"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "111"
          "paginaFinal" => "116"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "An&#225;lise da terap&#234;utica de redu&#231;&#227;o lip&#237;dica e dos fatores que afetam a regularidade da toma de estatinas em doentes com doen&#231;as cardiovasculares inseridos no Registo Profile"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1593
              "Ancho" => 1578
              "Tamanyo" => 149939
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Differences between groups by LDL level&#46; 1&#58; taking statins regularly&#59; 2 not taking statins&#59; 3&#58; taking statins irregularly&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Oleg Gaisenok, Sergey Martsevich, Svetlana Tripkosh, Yulia Lukina"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Oleg"
              "apellidos" => "Gaisenok"
            ]
            1 => array:2 [
              "nombre" => "Sergey"
              "apellidos" => "Martsevich"
            ]
            2 => array:2 [
              "nombre" => "Svetlana"
              "apellidos" => "Tripkosh"
            ]
            3 => array:2 [
              "nombre" => "Yulia"
              "apellidos" => "Lukina"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S0870255115000062"
        "doi" => "10.1016/j.repc.2014.08.021"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000062?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217420491500032X?idApp=UINPBA00004E"
    "url" => "/21742049/0000003400000002/v2_201502270337/S217420491500032X/v2_201502270337/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2174204915000306"
    "issn" => "21742049"
    "doi" => "10.1016/j.repce.2014.08.018"
    "estado" => "S300"
    "fechaPublicacion" => "2015-02-01"
    "aid" => "584"
    "copyright" => "Sociedade Portuguesa de Cardiologia"
    "documento" => "article"
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Cardiol. 2015;34:95-102"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3900
      "formatos" => array:3 [
        "EPUB" => 192
        "HTML" => 3003
        "PDF" => 705
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Continuous infusion or bolus injection of loop diuretics for patients admitted for severe acute heart failure&#58; Is one strategy better than the other&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "95"
          "paginaFinal" => "102"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Diur&#233;ticos da ansa em doentes com insufici&#234;ncia card&#237;aca aguda&#58; perfus&#227;o cont&#237;nua ou b&#243;lus &#8211; uma estrat&#233;gia melhor do que a outra&#63;"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1061
              "Ancho" => 2340
              "Tamanyo" => 148546
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Evolution of creatinine &#40;in &#956;mol&#47;l&#41; and blood urea nitrogen &#40;in mmol&#47;l&#41; levels during hospitalization in both groups&#46; BUN&#58; blood urea nitrogen&#59; Group A&#58; continuous infusion&#59; Group B&#58; bolus administration&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Francisca Caetano, Paula Mota, In&#234;s Almeida, Andreia Fernandes, Ana Botelho, Ant&#243;nio Leit&#227;o Marques"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Francisca"
              "apellidos" => "Caetano"
            ]
            1 => array:2 [
              "nombre" => "Paula"
              "apellidos" => "Mota"
            ]
            2 => array:2 [
              "nombre" => "In&#234;s"
              "apellidos" => "Almeida"
            ]
            3 => array:2 [
              "nombre" => "Andreia"
              "apellidos" => "Fernandes"
            ]
            4 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Botelho"
            ]
            5 => array:2 [
              "nombre" => "Ant&#243;nio"
              "apellidos" => "Leit&#227;o Marques"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S0870255115000049"
        "doi" => "10.1016/j.repc.2014.08.019"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0870255115000049?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000306?idApp=UINPBA00004E"
    "url" => "/21742049/0000003400000002/v2_201502270337/S2174204915000306/v2_201502270337/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
    "titulo" => "Prevalence of dyslipidemia in adolescents&#58; Comparison between definitions"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "103"
        "paginaFinal" => "109"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Crisieli M&#46; Tomeleri, Enio R&#46;V&#46; Ronque, Danilo R&#46;P&#46; Silva, Crivaldo G&#46; Cardoso J&#250;nior, R&#244;mulo A&#46; Fernandes, Denilson C&#46; Teixeira, D&#233;cio S&#46; Barbosa, Danielle Venturini, Alessandra M&#46; Okino, Jair A&#46; Oliveira, Edilson S&#46; Cyrino"
        "autores" => array:11 [
          0 => array:3 [
            "nombre" => "Crisieli M&#46;"
            "apellidos" => "Tomeleri"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Enio R&#46;V&#46;"
            "apellidos" => "Ronque"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:4 [
            "nombre" => "Danilo R&#46;P&#46;"
            "apellidos" => "Silva"
            "email" => array:1 [
              0 => "danilorpsilva&#64;gmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Crivaldo G&#46;"
            "apellidos" => "Cardoso J&#250;nior"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "R&#244;mulo A&#46;"
            "apellidos" => "Fernandes"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Denilson C&#46;"
            "apellidos" => "Teixeira"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "D&#233;cio S&#46;"
            "apellidos" => "Barbosa"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          7 => array:3 [
            "nombre" => "Danielle"
            "apellidos" => "Venturini"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          8 => array:3 [
            "nombre" => "Alessandra M&#46;"
            "apellidos" => "Okino"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          9 => array:3 [
            "nombre" => "Jair A&#46;"
            "apellidos" => "Oliveira"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          10 => array:3 [
            "nombre" => "Edilson S&#46;"
            "apellidos" => "Cyrino"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Study and Research Group in Metabolism&#44; Nutrition&#44; and Exercise GEPEMENE&#44; State University of Londrina &#8211; UEL&#44; Londrina&#44; Brazil"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Scientific Research Group Related to Physical Activity &#40;GICRAF&#41;&#44; Laboratory of Investigation in Exercise &#40;LIVE&#41;&#44; Department of Physical Education&#44; Center of Sciences and Technology&#44; UNESP Univ Estadual Paulista&#44; Presidente Prudente&#44; Brazil"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Department of Pathology&#44; Clinical and Toxicological Analysis&#44; Center of Health Sciences&#44; University Hospital&#44; State University of Londrina &#8211; UEL&#44; Londrina&#44; Brazil"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Preval&#234;ncia de dislipidemias em adolescentes&#58; compara&#231;&#227;o entre diferentes crit&#233;rios"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2024
            "Ancho" => 1638
            "Tamanyo" => 136954
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Prevalence of dyslipidemia subclassifications in male &#40;A&#41; &#40;n&#61;423&#41; and female &#40;B&#41; &#40;n&#61;577&#41; adolescents&#44; according to the three diagnostic definitions&#46; HDL-C&#58; high-density lipoprotein cholesterol&#59; LDL-C&#58; low-density lipoprotein cholesterol&#59; TC&#58; total cholesterol&#59; TG&#58; triglycerides&#46; &#42; p&#60;0&#46;05 &#40;BSC&#8800;NCEP&#8800;NHANES&#41;&#59; &#8224; p&#60;0&#46;05 &#40;BSC&#61;NCEP&#62;NHANES&#41;&#59; &#8225; p&#60;0&#46;05 &#40;BSC&#62;NCEP&#61;NHANES&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Coronary artery disease is one of the leading causes of death worldwide&#44;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">1&#44;2</span></a> and dyslipidemia is one of its main risk factors&#46;<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">3&#44;4</span></a> In adolescents&#44; an increase in the prevalence of dyslipidemia has been observed in several studies&#44; especially during the last decade&#46;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">5&#8211;11</span></a> Thus&#44; although it does not usually manifest in children and adolescents&#44; the beginning of the atherosclerotic process may occur early at these stages of life&#46;<a class="elsevierStyleCrossRefs" href="#bib0250"><span class="elsevierStyleSup">12&#8211;14</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Dyslipidemia is characterized by disorders in lipid metabolism&#44; which lead to changes in the serum levels of circulating lipids and lipoproteins&#44;<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">4&#44;15</span></a> and its subclassifications are established by determining the concentrations of triglycerides &#40;TG&#41;&#44; total cholesterol &#40;TC&#41; and its high-density lipoprotein &#40;HDL-C&#41; and low-density lipoprotein &#40;LDL-C&#41; fractions&#46; However&#44; one of the main problems faced by researchers and health care professionals is the indiscriminate use of different criteria for the diagnosis of dyslipidemia&#44; particularly in adolescents&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">According to the National Cholesterol Education Program &#40;NCEP&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">16</span></a> dyslipidemia is defined as HDL-C &#60;40 mg&#47;dl and TC&#44; LDL-C and TG levels &#8805;200&#44; &#8805;130 and &#8805;130 mg&#47;dl&#44; respectively&#46; This recommendation was adopted as a reference for the Brazilian population until the middle of the last decade&#44; with the support of the Brazilian Society of Cardiology &#40;BSC&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">15</span></a> In 2005&#44; the current NCEP definition was revised by the BSC&#44; which proposed more stringent cutoff points for adolescents&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">17</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">However&#44; none of the above cutoff points considered differences between the sexes&#44; which are particularly important regarding the maturation process&#46; A new proposal was therefore presented based on data from the National Health and Nutrition Examination Survey &#40;NHANES&#41;&#44; establishing cutoff points for TC&#44; LDL-C&#44; HDL-C and TG levels according to the variables of age and gender&#58; for boys aged 12&#8211;16&#44; 223&#8211;233 mg&#47;dl for TC&#44; 144&#8211;153 mg&#47;dl for LDL-C and 163&#8211;195 mg&#47;dl for TG&#59; and for girls&#44; 208&#8211;225 mg&#47;dl&#44; 136&#8211;145 mg&#47;dl and 158&#8211;180 mg&#47;dl for TC&#44; LDL-C and TG&#44; respectively&#46; HDL-C only shows variation in boys&#44; with values 39&#8211;46 mg&#47;dl&#44; for the age-group in question&#46;<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">18</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Considering the cutoff points recommended by each definition &#40;NCEP&#44; BSC and NHANES&#41;&#44; our hypothesis is that the adoption of different criteria may significantly affect the prevalence rates of dyslipidemia&#44; as was observed in recent studies analyzing the impact of the use of different criteria for the classification of metabolic syndrome in Brazilian adolescents&#46;<a class="elsevierStyleCrossRefs" href="#bib0285"><span class="elsevierStyleSup">19&#44;20</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">We believe that clarifying these issues could be of importance for both researchers and health professionals&#44; helping in the implementation of strategies to prevent and treat dyslipidemia in adolescence&#46; Thus&#44; the aim of the present study was to analyze possible differences in the prevalence rates of dyslipidemia in adolescents of both sexes&#44; based on three diagnostic definitions&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Methods</span><p id="par0035" class="elsevierStylePara elsevierViewall">The present study was based on data from a school-based cross-sectional study on the prevalence of metabolic syndrome and cardiovascular risk factors in adolescents from the city of Londrina&#44; Paran&#225; state&#44; Brazil&#44; carried out during the school year 2011&#46; Sample size was established using an equation based on population parameters&#44;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">21</span></a> which indicated a minimum of 848 subjects&#44; based on the mean prevalence of dyslipidemia of nearly 57&#37; reported in national studies&#44;<a class="elsevierStyleCrossRefs" href="#bib0220"><span class="elsevierStyleSup">6&#44;7&#44;10&#44;14</span></a> sample error of 4&#37;&#44; power of 80&#37;&#44; statistical significance of 5&#37; &#40;z&#61;1&#46;96&#41;&#44; design effect of 2&#46;0&#44; and increase of 20&#37; to compensate for possible losses and refusals&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Participants were selected by a two-stage sampling process&#46; Initially&#44; 55 public schools were listed and grouped according to their geographical location &#40;north&#44; south&#44; east&#44; west&#44; central&#44; and peripheral belt&#41;&#44; and two or three schools were then randomly selected in each of these regions&#46; All classes from the 6th to the 9th grades of elementary education were listed&#44; some of which were randomly selected to participate in the study&#46; All students enrolled in the selected classes were invited to participate&#46; Inclusion criteria were&#58; &#40;1&#41; reported good health status &#40;not frequently taking medication or being treated for disease&#41; and &#40;2&#41; return of the consent form duly signed by students and their parents or guardians&#46; Among the 1244 subjects eligible for the study&#44; 1000 adolescents &#40;57&#46;7&#37; female&#41; aged between 11 and 16 years and with complete data on the variables under analysis comprised the study sample&#46; The study was approved by the local research ethics committee &#40;decision 238&#47;2010&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Body weight and height were measured according to the procedures described in the literature&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">22</span></a> For determination of lipid profile&#44; 14 ml of venous blood was collected into vacuum tubes with separator gel and without anticoagulant by venous puncture in the antecubital fossa at an adapted classroom in each of the schools&#44; after a 12-hour fast prior to collection&#46; Samples were collected and immediately stored at a temperature of 8<span class="elsevierStyleHsp" style=""></span>&#176;C&#46; After one hour&#44; all samples were centrifuged for 3000 rpm for 15 min and serum aliquots were stored at &#8211;70<span class="elsevierStyleHsp" style=""></span>&#176;C until assayed&#46; Subsequently&#44; TG&#44; TC&#44; HDL-C and LDL-C concentrations were determined using a Siemens Dade Behring Dimension RxL Max chemistry analyzer&#46; Dyslipidemia and its subclassifications were diagnosed as abnormal serum levels of circulating lipids and lipoproteins&#44; based on criteria from NCEP&#44; BSC and NHANES&#46;</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Statistical analysis</span><p id="par0050" class="elsevierStylePara elsevierViewall">The Kolmogorov&#8211;Smirnov test was initially used to analyze data distribution&#46; Since the data showed normal distribution&#44; the general characteristics of the sample were expressed as mean and standard deviation&#46; The Kruskal-Wallis test followed by the Mann-Whitney test were used to compare lipid values between ages groups&#46; McNemar&#39;s test was applied to compare prevalences between the different definitions of dyslipidemia&#46; The kappa index was used to analyze agreement between the results obtained with the different diagnostic criteria&#46; Statistical significance was set at p&#60;0&#46;05&#46; All analyses were processed using the statistical package SPSS 17&#46;0&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">This study was partly funded by the Brazilian Council for Scientific and Technological Development &#40;483867&#47;2009-8&#41;&#46;</p></span></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Results</span><p id="par0060" class="elsevierStylePara elsevierViewall">The general characteristics of the sample stratified by gender are presented in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0065" class="elsevierStylePara elsevierViewall">The age- and gender-stratified mean values for lipid profile are presented in <a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#46; No significant differences were observed for the different ages in the female group&#46; However&#44; in the male group&#44; adolescents aged 11 years had a mean TC concentration of 172 mg&#47;dl&#44; which was significantly higher than that for age 14 &#40;p&#60;0&#46;05&#41;&#46; Furthermore&#44; mean HDL-C was also higher in boys aged 11 years compared to 13 and 15 years &#40;p&#60;0&#46;05&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a> shows prevalences according to gender&#46; The overall prevalence of dyslipidemia ranged from 24&#46;2&#37; &#40;NHANES&#41; to 61&#37; &#40;BSC&#41;&#46; Smaller differences &#40;4&#46;4&#37;&#41; were seen in the comparison between the internationally used definitions &#40;NHANES and NCEP&#41;&#46; Significant differences &#40;p&#60;0&#46;05&#41; were observed in the female group with regard to the three definitions&#44; while in the male group differences were limited to comparison between the BSC definition and the other definitions &#40;p&#60;0&#46;05&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">As for dyslipidemia subclassifications &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>&#41;&#44; the prevalence rates based on information obtained from the three definitions also varied considerably&#44; regardless of gender&#44; especially those for TC &#40;BSC 38&#46;3&#37;&#59; NCEP 11&#46;2&#37;&#59; NHANES 4&#46;8&#37;&#41; and HDL-C &#40;BSC 30&#46;0&#37;&#59; NCEP 15&#46;8&#37;&#59; NHANES 18&#46;4&#37;&#41;&#46; As for LDL-C and TG&#44; the cutoff points for which by BSC and NCEP were similar&#44; the prevalence rates were 10&#46;8&#37; vs&#46; 5&#46;9&#37; &#40;LDL-C&#41; and 4&#46;7&#37; vs&#46; 1&#46;3&#37; &#40;TG&#41; for BSC and NCEP and NHANES&#44; respectively&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0080" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a> displays agreement indicators for the different definitions&#46; In general&#44; although relative agreement was higher than 70&#37; in most cases&#44; kappa coefficients showed mostly low to moderate agreement &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Discussion</span><p id="par0085" class="elsevierStylePara elsevierViewall">The results of this study indicate that the indiscriminate use of different diagnostic criteria for the identification of dyslipidemia and its subclassifications in adolescents may lead to doubtful interpretations&#46; Thus&#44; of the 610 adolescents classified as dyslipidemic by the BSC &#40;61&#37;&#41;&#44; only 286 received the same classification by NCEP &#40;28&#46;6&#37;&#41; and 242 by NHANES &#40;24&#46;2&#37;&#41;&#46; It should be noted that&#44; in the present sample&#44; the adoption of the international definitions would result in a false negative rate of nearly 35&#37; according to the criteria of the BSC&#46; Therefore&#44; the lack of a single definition with appropriate discriminatory power may compromise both analysis of the prevalence rates of dyslipidemia in this population and decision-making for the implementation of therapeutic or prophylactic interventions&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Two previous studies<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">7&#44;23</span></a> analyzed the prevalence of dyslipidemia in a sample of children and adolescents based on the NCEP and BSC definitions&#46; In the first<a class="elsevierStyleCrossRef" href="#bib0305"><span class="elsevierStyleSup">23</span></a> the prevalence of dyslipidemia in private and public school students aged 5&#8211;16 years was 23&#37; and 4&#37;&#44; respectively &#40;NCEP definition&#41; and 49&#37; and 14&#37;&#44; respectively &#40;BSC definition&#41;&#46; In the second study&#44;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">7</span></a> in which the sample consisted of children aged 5&#8211;9 years&#44; the differences between the two definitions were smaller&#44; while the prevalence rates were higher &#40;NCEP 64&#46;5&#37; and BSC 68&#46;4&#37;&#41;&#46; Thus&#44; similarly to the present study&#44; the BSC definition found a higher prevalence of dyslipidemia than the NCEP definition&#46; However&#44; the differences between the two criteria were greater in the present study&#44; which can be explained at least in part by the different characteristics of the samples analyzed&#44; including sample size&#44; age and maturational status&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">When analysis of the information obtained in this study was extended to dyslipidemia subclassifications&#44; we found that&#44; regardless of gender&#44; high TC was the most frequent form of dyslipidemia according to the BSC definition&#44; whereas low HDL-C was the predominant anomaly based on the NHANES and NCEP definitions&#46; Of studies that adopted the BSC definition for the diagnosis of dyslipidemia in Brazilian adolescents&#44; this appears to be the first to identify high TC as the predominant form of dyslipidemia&#44; unlike other studies&#44; in which high TG<a class="elsevierStyleCrossRef" href="#bib0310"><span class="elsevierStyleSup">24</span></a> and low HDL-C<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">7&#44;25&#8211;27</span></a> were the main lipid anomalies&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">The findings from the present study are of concern&#44; since there is a continuous increase in cardiovascular risk with TC values higher than 180 mg&#47;dl&#59; it is thus important for health prevention that cutoff points remain below this value&#46;<a class="elsevierStyleCrossRef" href="#bib0330"><span class="elsevierStyleSup">28</span></a> On this basis&#44; the cutoff points proposed by the BSC definition are perhaps the most appropriate for the diagnosis of dyslipidemia in adolescents&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">On the other hand&#44; other studies with adolescents based on the NCEP definition found that the predominant forms of dyslipidemia were high TC&#44;<a class="elsevierStyleCrossRefs" href="#bib0330"><span class="elsevierStyleSup">28&#44;29</span></a> high TG&#44;<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">3&#44;4&#44;9&#44;30&#44;31</span></a> and low HDL-C&#46;<a class="elsevierStyleCrossRefs" href="#bib0220"><span class="elsevierStyleSup">6&#44;10&#44;32&#8211;34</span></a> Therefore&#44; depending on the cutoff point adopted and on the specific characteristics of the sample analyzed &#40;socioeconomic level&#44; nutritional status&#44; maturational level&#44; etc&#46;&#41;&#44; identification of the predominant form of dyslipidemia can change&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">Furthermore&#44; since the cutoff points proposed by the NCEP require upgrading<a class="elsevierStyleCrossRef" href="#bib0365"><span class="elsevierStyleSup">35</span></a> and changes in lipid levels during adolescence are dependent on age and maturity<a class="elsevierStyleCrossRef" href="#bib0370"><span class="elsevierStyleSup">36</span></a> and show wide variations between sexes&#44; the use of fixed cutoff points may be inappropriate in this age-group&#46; In fact&#44; when the mean lipid profile values of adolescents were compared in this study&#44; it was observed that younger boys have higher TC and HDL-C than older boys&#46; However&#44; this was not observed in girls&#46; Our results thus confirmed a gender-based difference&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">In addition&#44; there appears to be a need for tables with specific cutoff points for each population&#44; since besides the different behavior between the sexes&#44; variables of the lipid profile may be influenced by race and ethnicity&#46;<a class="elsevierStyleCrossRefs" href="#bib0375"><span class="elsevierStyleSup">37&#44;38</span></a> Furthermore&#44; when the lipid profile values in this study were compared to the other studies described above&#44;<a class="elsevierStyleCrossRefs" href="#bib0345"><span class="elsevierStyleSup">31&#44;38</span></a> we identified differences in TC&#44; with the highest values in Brazilian adolescents aged 11&#8211;15 years of both sexes&#46; On the other hand&#44; mean TG values were lower than those described by Yang et al&#46;<a class="elsevierStyleCrossRef" href="#bib0345"><span class="elsevierStyleSup">31</span></a> at all ages analyzed&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Considering that therapeutic or prophylactic measures should be implemented based on the categorization identified by the criteria adopted&#44; inaccurate diagnosis can result in ineffective strategies&#46; For example&#44; in cases or populations in which low HDL-C is found as the predominant dyslipidemic subclass&#44; increases in levels of physical activity and engagement in exercise programs may play a more important role than the adoption of other strategies for controlling other lipid alterations&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Some important limitations of the present study should be pointed out&#44; such as the lack of a gold standard for comparison between the different criteria&#44; which would be essential for sensitivity and specificity analysis&#46; Moreover&#44; there was no control for the maturational process&#44; which could have provided valuable information for better stratification of the sample and extrapolation of the results&#46; Additionally&#44; although this is a school-based population study&#44; generalization of the results is limited by the impact of the socioeconomic and cultural context on the behavior of the variables analyzed&#46; Finally&#44; the criteria analyzed were established on the basis of characteristics of other populations&#44; at a different time&#44; which also reduces the ecological validity of the present investigation&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">In conclusion&#44; the dyslipidemia prevalence rates found in adolescents of both genders in the present study were very high&#44; despite the differences in the estimates obtained by the different definitions analyzed&#46; The BSC definition&#44; with its more stringent cutoff points&#44; was the one that detected the highest rates&#44; regardless of gender and the different dyslipidemia subclassifications&#46; Finally&#44; the results of the present study suggest that the indiscriminate use of different diagnostic criteria to estimate the prevalence of dyslipidemia in adolescents may result in inaccurate interpretations&#44; which could compromise diagnosis and therefore the therapeutic and prophylactic measures to be taken&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Ethical disclosures</span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Protection of human and animal subjects</span><p id="par0135" class="elsevierStylePara elsevierViewall">The authors declare that the procedures followed were in accordance with the regulations of the relevant clinical research ethics committee and with those of the Code of Ethics of the World Medical Association &#40;Declaration of Helsinki&#41;&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Confidentiality of data</span><p id="par0140" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Right to privacy and informed consent</span><p id="par0145" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article&#46; The corresponding author is in possession of this document&#46;</p></span></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Conflicts of interest</span><p id="par0150" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:12 [
        0 => array:3 [
          "identificador" => "xres439420"
          "titulo" => "Abstract"
          "secciones" => array:5 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Introduction"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Objective"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Methods"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Results"
            ]
            4 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Conclusions"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec462609"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres439419"
          "titulo" => "Resumo"
          "secciones" => array:5 [
            0 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "Fundamento"
            ]
            1 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Objetivo"
            ]
            2 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "M&#233;todos"
            ]
            3 => array:2 [
              "identificador" => "abst0045"
              "titulo" => "Resultados"
            ]
            4 => array:2 [
              "identificador" => "abst0050"
              "titulo" => "Conclus&#245;es"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec462608"
          "titulo" => "Palavras-chave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:3 [
          "identificador" => "sec0010"
          "titulo" => "Methods"
          "secciones" => array:1 [
            0 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Statistical analysis"
            ]
          ]
        ]
        6 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Results"
        ]
        7 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Discussion"
        ]
        8 => array:3 [
          "identificador" => "sec0030"
          "titulo" => "Ethical disclosures"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Protection of human and animal subjects"
            ]
            1 => array:2 [
              "identificador" => "sec0040"
              "titulo" => "Confidentiality of data"
            ]
            2 => array:2 [
              "identificador" => "sec0045"
              "titulo" => "Right to privacy and informed consent"
            ]
          ]
        ]
        9 => array:2 [
          "identificador" => "sec0050"
          "titulo" => "Conflicts of interest"
        ]
        10 => array:2 [
          "identificador" => "xack131767"
          "titulo" => "Acknowledgments"
        ]
        11 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2014-02-24"
    "fechaAceptado" => "2014-08-16"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec462609"
          "palabras" => array:4 [
            0 => "Risk factors"
            1 => "Cardiovascular disease"
            2 => "Atherosclerosis"
            3 => "Youth"
          ]
        ]
      ]
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec462608"
          "palabras" => array:4 [
            0 => "Fatores de risco"
            1 => "Doen&#231;as cardiovasculares"
            2 => "Aterosclerose"
            3 => "Jovens"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The indiscriminate use of different diagnostic criteria for the definition of dyslipidemia may result in inaccurate interpretations&#44; which could compromise diagnosis and therefore the therapeutic and prophylactic actions to be taken&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To analyze possible differences in prevalence rates of dyslipidemia in adolescents based on three diagnostic definitions&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A cross-sectional study was conducted of a representative sample of Brazilian adolescents between 11 and 16 years of age&#46; Blood samples were collected from 1000 students &#40;423 boys and 577 girls&#41; to determine fasting total cholesterol &#40;TC&#41;&#44; HDL and LDL cholesterol&#44; and triglycerides &#40;TG&#41;&#46; The prevalence of dyslipidemia was established according to three definitions&#58; those of the National Cholesterol Education Program &#40;NCEP&#41;&#44; the Brazilian Society of Cardiology &#40;BSC&#41;&#44; and the National Health and Nutrition Examination Survey &#40;NHANES&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Significant differences &#40;p&#60;0&#46;01&#41; were found between the diagnostic criteria for TC &#40;BSC 38&#46;3&#37;&#59; NCEP 11&#46;2&#37;&#59; NHANES 4&#46;8&#37;&#41;&#44; HDL cholesterol &#40;BSC 30&#46;0&#37;&#59; NCEP 15&#46;8&#37; NHANES 18&#46;4&#37;&#41;&#44; LDL cholesterol &#40;BSC and NCEP 10&#46;8&#37; and NHANES 5&#46;9&#37;&#41;&#44; and TG &#40;BSC and NCEP 4&#46;7&#37; and NHANES 1&#46;3&#37;&#41;&#46; The overall prevalence of dyslipidemia was 61&#37; &#40;BSC&#41;&#44; 28&#46;6&#37; &#40;NCEP&#41; and 24&#46;2&#37; &#40;NHANES&#41;&#46; Agreement rates varied significantly &#40;kappa 0&#46;15&#8211;0&#46;90&#41;&#46;</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conclusions</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Although a high prevalence of dyslipidemia was observed in this study regardless of the diagnostic criteria used&#44; the wide variation in rates highlights the need to establish a single definition with appropriate discriminatory power for adolescents&#46;</p></span>"
        "secciones" => array:5 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introduction"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Objective"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Methods"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Results"
          ]
          4 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Conclusions"
          ]
        ]
      ]
      "pt" => array:3 [
        "titulo" => "Resumo"
        "resumen" => "<span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Fundamento</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">O uso indiscriminado de diferentes crit&#233;rios diagn&#243;sticos para a determina&#231;&#227;o de dislipidemias pode resultar em interpreta&#231;&#245;es imprecisas&#44; podendo comprometer o diagn&#243;stico e&#44; consequentemente&#44; as a&#231;&#245;es terap&#234;uticas e profil&#225;ticas a serem empregadas&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Objetivo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Analisar poss&#237;veis diferen&#231;as nas taxas de preval&#234;ncia de dislipidemias em adolescentes&#44; com base em tr&#234;s crit&#233;rios diagn&#243;sticos&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">M&#233;todos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Estudo transversal conduzido com uma amostra representativa de adolescentes brasileiros de 11 a 16 anos&#46; Amostras de sangue foram coletadas de 1000 escolares &#40;423 rapazes e 577 mo&#231;as&#41; para determina&#231;&#227;o do colesterol total &#40;CT&#41;&#44; HDL&#44; LDL e triglic&#233;rides &#40;TG&#41; em jejum&#46; A preval&#234;ncia de dislipidemias foi estabelecida com base em tr&#234;s crit&#233;rios diagn&#243;sticos&#58; <span class="elsevierStyleItalic">National Cholesterol Education Program</span> &#40;NCEP&#41;&#44; Sociedade Brasileira de Cardiologia &#40;SBC&#41; e <span class="elsevierStyleItalic">National Health and Nutrition Examination Survey</span> &#40;NHANES&#41;&#46;</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Diferen&#231;as significantes &#40;p&#60;0&#44;01&#41; foram identificadas entre os crit&#233;rios diagn&#243;sticos analisados para CT &#40;SBC&#61;38&#44;3&#37;&#59; NCEP&#61;11&#44;2&#37;&#59; NHANES&#61;4&#44;8&#37;&#41;&#44; HDL &#40;SBC&#61;30&#44;0&#37;&#59; NCEP&#61;15&#44;8&#37;&#59; NHANES&#61;18&#44;4&#37;&#41;&#44; LDL &#40;SBC&#47;NCEP&#61;10&#44;8&#37; e NHANES&#61;5&#44;9&#37;&#41; e TG &#40;SBC&#47;NCEP&#61;4&#44;7&#37; e NHANES&#61;1&#44;3&#37;&#41;&#46; No geral&#44; a preval&#234;ncia de dislipidemias foi na ordem de 61&#37; &#40;SBC&#41;&#59; 28&#44;6&#37; &#40;NCEP&#41; e 24&#44;2&#37; &#40;NHANES&#41;&#46; Os &#237;ndices de concord&#226;ncia variaram amplamente &#40;Kappa&#61;0&#44;15 a 0&#44;90&#41;&#46;</p></span> <span id="abst0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conclus&#245;es</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Embora uma elevada preval&#234;ncia de dislipidemias tenha sido identificada neste estudo&#44; independente dos crit&#233;rios diagn&#243;sticos utilizados&#44; a ampla varia&#231;&#227;o nas taxas encontradas refor&#231;a a necessidade do estabelecimento de um crit&#233;rio &#250;nico e com poder de discrimina&#231;&#227;o adequado para adolescentes&#46;</p></span>"
        "secciones" => array:5 [
          0 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Fundamento"
          ]
          1 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Objetivo"
          ]
          2 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "M&#233;todos"
          ]
          3 => array:2 [
            "identificador" => "abst0045"
            "titulo" => "Resultados"
          ]
          4 => array:2 [
            "identificador" => "abst0050"
            "titulo" => "Conclus&#245;es"
          ]
        ]
      ]
    ]
    "multimedia" => array:5 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1046
            "Ancho" => 1601
            "Tamanyo" => 74699
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Prevalence of dyslipidemia in male &#40;n&#61;423&#41; and female &#40;n&#61;577&#41; adolescents&#44; according to the three diagnostic definitions&#46; &#42; p&#60;0&#46;05 vs&#46; &#40;BSC&#62;NCEP&#61;NHANES&#41;&#59; &#8224; p&#60;0&#46;05 &#40;BSC&#8800;NCEP&#8800;NHANES&#41;&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2024
            "Ancho" => 1638
            "Tamanyo" => 136954
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Prevalence of dyslipidemia subclassifications in male &#40;A&#41; &#40;n&#61;423&#41; and female &#40;B&#41; &#40;n&#61;577&#41; adolescents&#44; according to the three diagnostic definitions&#46; HDL-C&#58; high-density lipoprotein cholesterol&#59; LDL-C&#58; low-density lipoprotein cholesterol&#59; TC&#58; total cholesterol&#59; TG&#58; triglycerides&#46; &#42; p&#60;0&#46;05 &#40;BSC&#8800;NCEP&#8800;NHANES&#41;&#59; &#8224; p&#60;0&#46;05 &#40;BSC&#61;NCEP&#62;NHANES&#41;&#59; &#8225; p&#60;0&#46;05 &#40;BSC&#62;NCEP&#61;NHANES&#41;&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">BMI&#58; body mass index&#59; HDL-C&#58; high-density lipoprotein cholesterol&#59; LDL-C&#58; low-density lipoprotein cholesterol&#59; TC&#58; total cholesterol&#59; TG&#58; triglycerides&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Boys &#40;n&#61;423&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Girls &#40;n&#61;577&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Total &#40;n&#61;1000&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top">Age &#40;years&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13&#46;1&#177;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&#46;8&#177;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&#46;9&#177;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top">Weight &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48&#46;7&#177;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">47&#46;5&#177;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48&#46;0&#177;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top">Height &#40;m&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">155&#46;9&#177;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">154&#46;0&#177;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">154&#46;8&#177;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top">BMI &#40;kg&#47;m<span class="elsevierStyleSup">2</span>&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#46;8&#177;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#46;9&#177;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#46;8&#177;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top">TC &#40;mg&#47;dl&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">163&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">165&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">164&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top">LDL-C &#40;mg&#47;dl&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">99&#177;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">99&#177;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">99&#177;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top">HDL-C &#40;mg&#47;dl&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#177;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#177;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#177;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top">TG &#40;mg&#47;dl&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">61&#177;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">66&#177;35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">64&#177;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab685939.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">General characteristics of the sample according to gender&#46;</p>"
        ]
      ]
      3 => array:7 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">LDL-C&#58; low-density lipoprotein cholesterol&#59; HDL&#58; high-density lipoprotein cholesterol&#59; TC&#58; total cholesterol&#59; TG&#58; triglycerides&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col">Age&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="4" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Boys</th><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="4" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Girls</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">TC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">LDL-C&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">HDL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">TG&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">TC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">LDL-C&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">HDL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">TG&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " align="char" valign="top">11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">69&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">172&#177;28<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">102&#177;24<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">57&#177;15<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">62&#177;32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">117&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">169&#177;27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">104&#177;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">51&#177;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">67&#177;31&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="char" valign="top">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">166&#177;25<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">101&#177;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">53&#177;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">58&#177;35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">149&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">165&#177;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">98&#177;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">53&#177;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68&#177;45&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="char" valign="top">13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">167&#177;26<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">103&#177;23<a class="elsevierStyleCrossRef" href="#tblfn0025"><span class="elsevierStyleSup">e</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">50&#177;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68&#177;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">127&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">163&#177;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97&#177;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">54&#177;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">62&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="char" valign="top">14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">102&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">158&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#177;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">51&#177;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">128&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">165&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">99&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">53&#177;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68&#177;32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="char" valign="top">15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">155&#177;32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97&#177;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">45&#177;11<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">62&#177;35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">158&#177;31&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">96&#177;21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">49&#177;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68&#177;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="char" valign="top">16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">150&#177;21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">90&#177;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">49&#177;17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">55&#177;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">152&#177;21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">93&#177;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">47&#177;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63&#177;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab685937.png"
              ]
            ]
          ]
          "notaPie" => array:5 [
            0 => array:3 [
              "identificador" => "tblfn0005"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0005">p&#60;0&#46;05 vs&#46; 14&#44; 15 and 16 age-group&#46;</p>"
            ]
            1 => array:3 [
              "identificador" => "tblfn0010"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0010">p&#60;0&#46;05 vs&#46; 13&#44; 14&#44; 15 and 16 age-group&#46;</p>"
            ]
            2 => array:3 [
              "identificador" => "tblfn0015"
              "etiqueta" => "c"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0015">p&#60;0&#46;05 vs&#46; 16 age-group&#46;</p>"
            ]
            3 => array:3 [
              "identificador" => "tblfn0020"
              "etiqueta" => "d"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0020">p&#60;0&#46;05 vs&#46; 12&#44; 13 and 14 age-group&#46;</p>"
            ]
            4 => array:3 [
              "identificador" => "tblfn0025"
              "etiqueta" => "e"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0025">p&#60;0&#46;05 vs&#46; 14 and 16 age-group&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Mean values and standard deviations of total cholesterol&#44; LDL cholesterol&#44; HDL cholesterol and triglycerides according to age and gender&#46;</p>"
        ]
      ]
      4 => array:7 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">All kappa coefficients were significant &#40;p&#60;0&#46;01&#41;&#46; BSC&#58; Brazilian Society of Cardiology&#59; CI&#58; confidence interval&#59; HDL-C&#58; high-density lipoprotein cholesterol&#59; LDL-C&#58; low-density lipoprotein cholesterol&#59; NCEP&#58; National Cholesterol Education Program&#59; NHANES&#58; National Health and Nutrition Examination Survey&#59; TC&#58; total cholesterol&#59; TG&#58; triglycerides&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Boys &#40;n&#61;423&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Girls &#40;n&#61;577&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Total &#40;n&#61;1000&#41;</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Kappa &#40;95&#37; CI&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Kappa &#40;95&#37; CI&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Kappa &#40;95&#37; CI&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleItalic">TC</span></td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BSC vs&#46; NCEP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;34 &#40;0&#46;26&#8211;0&#46;42&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">74&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;34 &#40;0&#46;27&#8211;0&#46;40&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">72&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;34 &#40;0&#46;29&#8211;0&#46;39&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">72&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BSC vs&#46; NHANES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;10 &#40;0&#46;05&#8211;0&#46;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">66&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;18 &#40;0&#46;13&#8211;0&#46;24&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">66&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;15 &#40;0&#46;11&#8211;0&#46;19&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">66&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>NCEP vs&#46; NHANES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;40 &#40;0&#46;24&#8211;0&#46;56&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">92&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;67 &#40;0&#46;56&#8211;0&#46;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">94&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;57 &#40;0&#46;48&#8211;0&#46;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">93&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleItalic">LDL-C</span></td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BSC vs&#46; NCEP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BSC vs&#46; NHANES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;49 &#40;0&#46;33&#8211;0&#46;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">93&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;79 &#40;0&#46;70&#8211;0&#46;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">96&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;68 &#40;0&#46;60&#8211;0&#46;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>NCEP vs&#46; NHANES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;49 &#40;0&#46;33&#8211;0&#46;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">93&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;79 &#40;0&#46;70&#8211;0&#46;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">96&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;68 &#40;0&#46;60&#8211;0&#46;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleItalic">HDL-C</span></td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BSC vs&#46; NCEP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;59 &#40;0&#46;51&#8211;0&#46;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">83&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;62 &#40;0&#46;54&#8211;0&#46;70&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">87&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;61 &#40;0&#46;55&#8211;0&#46;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">85&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BSC vs&#46; NHANES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;75 &#40;0&#46;68&#8211;0&#46;82&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">89&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;62 &#40;0&#46;55&#8211;0&#46;70&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">87&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;69 &#40;0&#46;64&#8211;0&#46;74&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">88&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>NCEP vs&#46; NHANES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;82 &#40;0&#46;74&#8211;0&#46;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">93&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;90 &#40;0&#46;87&#8211;0&#46;94&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleItalic">TG</span></td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BSC vs&#46; NCEP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>BSC vs&#46; NHANES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;39 &#40;0&#46;17&#8211;0&#46;61&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;46 &#40;0&#46;24&#8211;0&#46;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;42 &#40;0&#46;27&#8211;0&#46;58&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">96&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>NCEP vs&#46; NHANES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;39 &#40;0&#46;17&#8211;0&#46;61&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;46 &#40;0&#46;24&#8211;0&#46;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;42 &#40;0&#46;27&#8211;0&#46;58&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">96&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab685938.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Analysis of agreement between the three diagnostic definitions used to assess the prevalence of dyslipidemia in adolescents&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:38 [
            0 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pathobiological determinants of atherosclerosis in youth risk scores are associated with early and advanced atherosclerosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46;A&#46; McMahan"
                            1 => "S&#46;S&#46; Gidding"
                            2 => "G&#46;T&#46; Malcon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1542/peds.2006-0970"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatrics"
                        "fecha" => "2006"
                        "volumen" => "118"
                        "paginaInicial" => "1447"
                        "paginaFinal" => "1455"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17015535"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preventing chronic diseases&#58; a vital investment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "World Health Organization"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2005"
                        "editorial" => "World Health Organization"
                        "editorialLocalizacion" => "Switzerland"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "L&#237;pides e lipoproteinas s&#233;ricos em crian&#231;as e adolescentes de um hospital universit&#225;rio p&#250;blico"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46;C&#46; Faria"
                            1 => "F&#46;B&#46; Dalpino"
                            2 => "R&#46; Takata"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Paul Pediatr"
                        "fecha" => "2008"
                        "volumen" => "26"
                        "paginaInicial" => "54"
                        "paginaFinal" => "58"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dislipidemias na inf&#226;ncia e adolesc&#234;ncia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "I&#46;C&#46;B&#46; Giuliano"
                            1 => "B&#46; Caramelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Pediatria"
                        "fecha" => "2008"
                        "volumen" => "29"
                        "paginaInicial" => "275"
                        "paginaFinal" => "285"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Associated factors to total cholesterol&#58; school based study in Southern Brazil"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46;L&#46;A&#46; Bergmann"
                            1 => "G&#46;G&#46; Bergmann"
                            2 => "R&#46; Halpern"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "2011"
                        "volumen" => "97"
                        "paginaInicial" => "17"
                        "paginaFinal" => "25"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21625818"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perfil lip&#237;dico e estado nutricional de adolescentes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D&#46;F&#46; Carvalho"
                            1 => "A&#46;A&#46; Paiva"
                            2 => "A&#46;S&#46;O&#46; Melo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Bras Epidemiol"
                        "fecha" => "2007"
                        "volumen" => "10"
                        "paginaInicial" => "491"
                        "paginaFinal" => "498"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preval&#234;ncia em crian&#231;as de fatores de risco para as doen&#231;as cardiovasculares"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;S&#46; Gama"
                            1 => "M&#46;S&#46; Carvalho"
                            2 => "C&#46;R&#46;M&#46; Chaves"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cad Sa&#250;de P&#250;blica"
                        "fecha" => "2007"
                        "volumen" => "23"
                        "paginaInicial" => "2239"
                        "paginaFinal" => "2245"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17700959"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Serum lipids in school kids and adolescents from Florian&#243;polis&#44; SC&#44; Brazil &#8211; Healthy Floripa 2040 Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "I&#46;C&#46;B&#46; Giuliano"
                            1 => "M&#46;S&#46;S&#46;A&#46; Coutinho"
                            2 => "S&#46;F&#46;T&#46; Freitas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "/S0066-782X2005001400003"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "2005"
                        "volumen" => "85"
                        "paginaInicial" => "85"
                        "paginaFinal" => "91"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16113845"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of pediatric dyslipidemia&#58; comparison of a population-based claims database to national surveys"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46; Li"
                            1 => "S&#46;P&#46; Motsko"
                            2 => "E&#46;L&#46; Goehring Jr&#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/pds.1982"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pharmacoepidemiol Drug Saf"
                        "fecha" => "2010"
                        "volumen" => "19"
                        "paginaInicial" => "1031"
                        "paginaFinal" => "1040"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20602343"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dyslipidemia in schoolchildren from private schools in Bel&#233;m"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;S&#46; Ribas"
                            1 => "L&#46;C&#46;S&#46; Silva"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "2009"
                        "volumen" => "92"
                        "paginaInicial" => "446"
                        "paginaFinal" => "451"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lipid and lipoprotein profiles and prevalence of dyslipidemia in Mexican adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "R&#46;P&#46; S&#225;nchez"
                            1 => "C&#46;P&#46; Romero"
                            2 => "J&#46;Z&#46; Gonz&#225;lez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.metabol.2007.07.009"
                      "Revista" => array:6 [
                        "tituloSerie" => "Metabolism"
                        "fecha" => "2007"
                        "volumen" => "56"
                        "paginaInicial" => "1666"
                        "paginaFinal" => "1672"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17998019"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "In utero programming of cardiovascular disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46;J&#46; Barker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Theriogenology"
                        "fecha" => "2000"
                        "volumen" => "53"
                        "paginaInicial" => "555"
                        "paginaFinal" => "574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10735050"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults&#46; The Bogalusa Heart Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46;S&#46; Berenson"
                            1 => "S&#46;R&#46; Srinivasan"
                            2 => "W&#46; Bao"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM199806043382302"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1998"
                        "volumen" => "338"
                        "paginaInicial" => "1650"
                        "paginaFinal" => "1656"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9614255"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk factors for atherosclerosis in children and adolescents with family history of premature coronary artery disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46;C&#46; Romaldini"
                            1 => "H&#46; Issler"
                            2 => "A&#46;L&#46; Cardoso"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Pediatr &#40;Rio J&#41;"
                        "fecha" => "2004"
                        "volumen" => "80"
                        "paginaInicial" => "135"
                        "paginaFinal" => "140"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "III Diretrizes Brasileiras sobre Dislipidemias e Diretriz de Preven&#231;&#227;o da Aterosclerose do Departamento de Aterosclerose"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Sociedade Brasileira de Cardiologia &#40;BSC&#41;"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "2001"
                        "volumen" => "77"
                        "numero" => "supl&#46; 1"
                        "paginaInicial" => "1"
                        "paginaFinal" => "48"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11781591"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Expert panel on detection&#44; evaluation&#44; and treatment of high blood cholesterol in adults &#40;Adult Treatment Panel III&#41; final report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "National Cholesterol Education Program &#40;NCEP&#41; Expert Panel on Detection&#44; Evaluation&#44; and Treatment of High Blood Cholesterol in Adults &#40;Adult Treatment Panel III&#41;"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "2002"
                        "volumen" => "106"
                        "paginaInicial" => "3143"
                        "paginaFinal" => "3421"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12485966"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "I guidelines for prevention of atherosclerosis in childhood and adolescence"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Brazilian Society of Cardiology &#40;BSC&#41;"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "/S0066-782X2005001300002"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "2005"
                        "volumen" => "85"
                        "paginaInicial" => "3"
                        "paginaFinal" => "36"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16041447"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Distribution of lipoproteins by age and gender in adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;J&#46; Jolliffe"
                            1 => "I&#46; Janssen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/CIRCULATIONAHA.106.620864"
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "2006"
                        "volumen" => "114"
                        "paginaInicial" => "1056"
                        "paginaFinal" => "1062"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16940191"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Metabolic syndrome&#58; comparison of diagnosis criteria"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46;L&#46; Cavali"
                            1 => "M&#46;A&#46; Escriv&#227;o"
                            2 => "R&#46;S&#46; Brasileiro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Pediatr &#40;Rio J&#41;"
                        "fecha" => "2010"
                        "volumen" => "86"
                        "paginaInicial" => "325"
                        "paginaFinal" => "330"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Metabolic syndrome in obese adolescents&#58; a comparison of three different diagnostic criteria"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "R&#46;F&#46; Costa"
                            1 => "N&#46;S&#46; Santos"
                            2 => "N&#46;P&#46; Goldraich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Pediatr &#40;Rio J&#41;"
                        "fecha" => "2012"
                        "volumen" => "88"
                        "paginaInicial" => "303"
                        "paginaFinal" => "309"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0295"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A l&#243;gica da determina&#231;&#227;o do tamanho da amostra em investiga&#231;&#245;es epidemiol&#243;gicas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;R&#46; Luiz"
                            1 => "M&#46;M&#46;F&#46; Magnanini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cad Sa&#250;de Colet"
                        "fecha" => "2000"
                        "volumen" => "8"
                        "paginaInicial" => "9"
                        "paginaFinal" => "28"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0300"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Stature&#44; recumbent length&#44; and weight"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46;C&#46; Gordon"
                            1 => "W&#46;C&#46; Chumlea"
                            2 => "A&#46;F&#46; Roche"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Anthropometric standardizing reference manual"
                        "paginaInicial" => "3"
                        "paginaFinal" => "8"
                        "serieFecha" => "1988"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0305"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lipid profile analysis in school children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46; Scherr"
                            1 => "C&#46;K&#46; Magalh&#227;es"
                            2 => "W&#46; Malheiros"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "2007"
                        "volumen" => "89"
                        "paginaInicial" => "73"
                        "paginaFinal" => "78"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0310"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dyslipidemia among adolescents and children from Pernambuco"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46; Franca"
                            1 => "J&#46;G&#46;B&#46; Alves"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "2006"
                        "volumen" => "87"
                        "paginaInicial" => "722"
                        "paginaFinal" => "727"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17262109"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0315"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Avalia&#231;&#227;o do perfil lip&#237;dico em alunos de 10 a 18 anos em uma escola particular do munic&#237;pio de Carazinho-RS"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;L&#46; Kerber"
                            1 => "A&#46;G&#46;U&#46; Antunes"
                            2 => "C&#46; Cavalette"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Bras Anal Clin"
                        "fecha" => "2010"
                        "volumen" => "42"
                        "paginaInicial" => "231"
                        "paginaFinal" => "234"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0320"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association between dyslipidemia and anthropometric indicators in adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46;C&#46; Vieira Cunha Lima"
                            1 => "C&#46; Oliveira Lyra"
                            2 => "L&#46; Galv&#227;o Bacurau Pinheiro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1590/S0212-16112011000200010"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nutr Hosp"
                        "fecha" => "2011"
                        "volumen" => "26"
                        "paginaInicial" => "304"
                        "paginaFinal" => "310"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21666967"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0325"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lipid profile of schoolchildren from Recife &#8211; PE"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "P&#46;B&#46; Pereira"
                            1 => "I&#46;K&#46;G&#46; Arruda"
                            2 => "A&#46;M&#46;T&#46;S&#46; Cavalcanti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "2010"
                        "volumen" => "95"
                        "paginaInicial" => "606"
                        "paginaFinal" => "613"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20944894"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0330"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fatores de risco de aterosclerose na inf&#226;ncia&#46; Um estudo epidemiol&#243;gico"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "Z&#46;R&#46;S&#46; Gerber"
                            1 => "P&#46; Zielinsky"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arq Bras Cardiol"
                        "fecha" => "1997"
                        "volumen" => "69"
                        "paginaInicial" => "231"
                        "paginaFinal" => "236"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9595714"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0335"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of dyslipidemia in non-obese prepubertal children and its association with family history of diabetes&#44; high blood pressure&#44; and obesity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46; Guerrero-Romero"
                            1 => "Rodrigues-Mor&#225;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.arcmed.2006.06.003"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Med Res"
                        "fecha" => "2006"
                        "volumen" => "37"
                        "paginaInicial" => "1015"
                        "paginaFinal" => "1021"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17045120"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0340"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Colesterolemia&#44; trigliceridemia e excesso de peso em escolares de Santa Maria&#44; RS&#44; Brasil"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46;C&#46; Lunardi"
                            1 => "C&#46;M&#46; Moreira"
                            2 => "D&#46;L&#46; Santos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Bras Med Esporte"
                        "fecha" => "2010"
                        "volumen" => "16"
                        "paginaInicial" => "250"
                        "paginaFinal" => "253"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0345"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Serum lipid concentrations&#44; prevalence of dyslipidemia and percentage eligible for pharmacological treatment of Korean children and adolescents&#59; data from the Korea National Health and Nutrition Examination Survey IV &#40;2007&#8211;2009&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46; Yang"
                            1 => "J&#46;S&#46; Hwang"
                            2 => "H&#46;K&#46; Park"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0049253"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2012"
                        "volumen" => "7"
                        "paginaInicial" => "e49253"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23251338"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0350"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perfil lip&#237;dico e obesidade em escolares de baixa renda"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46;P&#46; Grillo"
                            1 => "S&#46;P&#46; Crispim"
                            2 => "N&#46;A&#46; Siebert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Bras Epidemiol"
                        "fecha" => "2005"
                        "volumen" => "8"
                        "paginaInicial" => "75"
                        "paginaFinal" => "78"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0355"
              "etiqueta" => "33"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Trends in serum lipids among US youths aged 6 to 19 years&#44; 1988&#8211;2010"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46;K&#46; Kit"
                            1 => "M&#46;D&#46; Carroll"
                            2 => "D&#46;A&#46; Lacher"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jama.2012.9136"
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "2012"
                        "volumen" => "308"
                        "paginaInicial" => "591"
                        "paginaFinal" => "600"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22871871"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0360"
              "etiqueta" => "34"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lipid profiles and prevalence of dyslipidemia in schoolchildren in south Khorasan Province&#44; Eastern Iran"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Fesharakinia"
                            1 => "A&#46; Zarban"
                            2 => "G&#46;R&#46; Sharifzadeh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Iran Med"
                        "fecha" => "2008"
                        "volumen" => "11"
                        "paginaInicial" => "598"
                        "paginaFinal" => "601"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18976028"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0365"
              "etiqueta" => "35"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "New cholesterol guidelines for children&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46;S&#46; Gidding"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/CIRCULATIONAHA.106.647891"
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "2006"
                        "volumen" => "114"
                        "paginaInicial" => "989"
                        "paginaFinal" => "991"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16952994"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0370"
              "etiqueta" => "36"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sensitivity and specificity of pediatric lipid determinations for adult lipid status&#58; findings from the Princeton Lipid Research Clinics Prevalence Program Follow-up Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46;A&#46; Friedman"
                            1 => "J&#46;A&#46; Morrison"
                            2 => "S&#46;R&#46; Daniels"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1542/peds.2005-2968"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatrics"
                        "fecha" => "2006"
                        "volumen" => "118"
                        "paginaInicial" => "165"
                        "paginaFinal" => "172"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16818562"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib0375"
              "etiqueta" => "37"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Worldwide distribution of blood lipids and lipoproteins in childhood and adolescence&#58; a review study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46; Brotons"
                            1 => "A&#46; Ribeira"
                            2 => "R&#46;M&#46; Perich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Atherosclerosis"
                        "fecha" => "1998"
                        "volumen" => "139"
                        "paginaInicial" => "1"
                        "paginaFinal" => "9"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9699886"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib0380"
              "etiqueta" => "38"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Concentrations of low-density lipoprotein cholesterol and total cholesterol among children and adolescents in the United States"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "E&#46;S&#46; Ford"
                            1 => "C&#46; Li"
                            2 => "G&#46; Zhao"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/CIRCULATIONAHA.108.816769"
                      "Revista" => array:6 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "2009"
                        "volumen" => "119"
                        "paginaInicial" => "1108"
                        "paginaFinal" => "1115"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19221218"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
    "agradecimientos" => array:1 [
      0 => array:4 [
        "identificador" => "xack131767"
        "titulo" => "Acknowledgments"
        "texto" => "<p id="par0155" class="elsevierStylePara elsevierViewall">We would like to thank the participants who voluntarily contributed to this study&#44; the Local Education Authority of the city of Londrina&#44; Brazil&#44; and the 10 public schools which made this entire project possible&#46; This study was supported &#40;Process 483867&#47;2009-8&#41; by the Council for Scientific and Technological Development &#40;CNPq&#47;Brazil&#41;&#46; The authors E&#46;R&#46;V&#46;R&#46; and D&#46;P&#46;R&#46;S&#46; were supported by the CNPq and E&#46;S&#46;C&#46; was supported by the Coordination of Improvement of Higher Education Personnel &#40;CAPES&#47;Brazil&#41;&#46;</p>"
        "vista" => "all"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21742049/0000003400000002/v2_201502270337/S2174204915000318/v2_201502270337/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9912"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original article"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21742049/0000003400000002/v2_201502270337/S2174204915000318/v2_201502270337/en/main.pdf?idApp=UINPBA00004E&text.app=https://revportcardiol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2174204915000318?idApp=UINPBA00004E"
]

Article information

ISSN: 21742049
Original language: English

DOI:10.1016/j.repce.2014.08.019

The statistics are updated each day

Year/Month	Html	Pdf	Total

2024 November	8	7	15
2024 October	50	37	87
2024 September	63	29	92
2024 August	60	26	86
2024 July	48	29	77
2024 June	43	31	74
2024 May	54	23	77
2024 April	39	24	63
2024 March	39	20	59
2024 February	33	21	54
2024 January	30	27	57
2023 December	37	25	62
2023 November	46	21	67
2023 October	34	22	56
2023 September	44	21	65
2023 August	43	23	66
2023 July	42	11	53
2023 June	35	10	45
2023 May	45	24	69
2023 April	19	5	24
2023 March	34	16	50
2023 February	26	24	50
2023 January	31	10	41
2022 December	19	14	33
2022 November	25	31	56
2022 October	28	14	42
2022 September	31	38	69
2022 August	23	29	52
2022 July	44	35	79
2022 June	21	20	41
2022 May	22	28	50
2022 April	29	22	51
2022 March	31	37	68
2022 February	31	26	57
2022 January	24	29	53
2021 December	16	19	35
2021 November	34	41	75
2021 October	28	36	64
2021 September	24	28	52
2021 August	23	30	53
2021 July	21	28	49
2021 June	27	24	51
2021 May	24	18	42
2021 April	30	37	67
2021 March	33	15	48
2021 February	37	15	52
2021 January	35	12	47
2020 December	27	8	35
2020 November	25	9	34
2020 October	23	9	32
2020 September	27	7	34
2020 August	17	3	20
2020 July	35	4	39
2020 June	43	4	47
2020 May	36	5	41
2020 April	30	22	52
2020 March	48	7	55
2020 February	59	22	81
2020 January	32	8	40
2019 December	46	7	53
2019 November	25	12	37
2019 October	37	13	50
2019 September	24	12	36
2019 August	24	7	31
2019 July	40	11	51
2019 June	32	11	43
2019 May	22	13	35
2019 April	33	19	52
2019 March	53	10	63
2019 February	61	11	72
2019 January	60	7	67
2018 December	109	10	119
2018 November	256	13	269
2018 October	562	25	587
2018 September	81	16	97
2018 August	97	21	118
2018 July	55	13	68
2018 June	72	16	88
2018 May	68	20	88
2018 April	195	5	200
2018 March	83	10	93
2018 February	95	12	107
2018 January	78	7	85
2017 December	120	21	141
2017 November	82	16	98
2017 October	37	14	51
2017 September	32	14	46
2017 August	36	13	49
2017 July	24	19	43
2017 June	39	29	68
2017 May	40	19	59
2017 April	30	14	44
2017 March	22	52	74
2017 February	32	10	42
2017 January	39	6	45
2016 December	48	14	62
2016 November	39	7	46
2016 October	46	8	54
2016 September	23	8	31
2016 August	16	0	16
2016 July	19	8	27
2016 June	10	8	18
2016 May	13	4	17
2016 April	14	1	15
2016 March	16	7	23
2016 February	29	20	49
2016 January	20	12	32
2015 December	13	10	23
2015 November	15	12	27
2015 October	26	13	39
2015 September	20	9	29
2015 August	29	7	36
2015 July	7	5	12
2015 June	18	2	20
2015 May	39	12	51
2015 April	26	7	33
2015 March	41	13	54
2015 February	1	1	2

Show all

Indexed in:

Follow us:

Statistics

Indexed in:

Follow us:

Statistics

Subscribe to our newsletter