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Vol. 30. Issue 9.
Pages 727-729 (September 2011)
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Vol. 30. Issue 9.
Pages 727-729 (September 2011)
Caso Clínico
Open Access
Arterial thrombosis and acute myocardial infarction with angiographically normal coronary arteries in a woman heterozygous for both factor V Leiden and prothrombin mutation
Trombose arterial e infarto agudo do miocárdio com artérias coronárias angiograficamente normais em mulher heterozigota para fator V de Leiden e mutação do gene da protrombina
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João Gaspara, Cláudio Benchimolb, Telma Gadelhac, Guilherme Loures Pennad,
Corresponding author
guipenna@terra.com.br

Corresponding author:.
a Internal Medicine, Hospital de Ipanema, Hospital Samaritano, Rio de Janeiro, Brazil
b Cardiology Service, Federal University of Rio de Janeiro, Hospital Samaritano, Rio de Janeiro, Brazil
c Hematology Service, Federal University of Rio de Janeiro, Hospital Samaritano, Rio de Janeiro, Brazil
d Internal Medicine, Casa de Saúde São Jose, Hospital Samaritano, Rio de Janeiro, Brazil
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Abstract

Thirteen years after her last thrombotic event, anticoagulation was discontinued in a patient with combined thrombophilia involving mutation in factor V and G20210A polymorphism of the prothrombin gene. The only history was of arterial thrombosis. Three months later she presented a transmural myocardial infarction caused by coronary thrombosis.

Keywords:
Arterial thrombosis
Myocardial infarction
Thrombophilia
Resumo

Após treze anos do último evento trombótico, a anticoagulação foi interrompida numa paciente com associação de trombofilia factor V de Leiden e gene mutante da protrombina G20210A. Ela possuía história de tromboses arteriais. Três meses após, a paciente apresentou enfarte transmural do miocárdio devido à trombose coronariana.

Palavras-chave:
Trombose arterial
Enfarte do miocárdio
Trombofilia
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Copyright © 2011. Sociedade Portuguesa de Cardiologia
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