TY - JOUR T1 - Long-term outcomes of non-contact multi-electrode balloon catheter mapping-guided ablation of ventricular arrhythmias originating from the outflow tract JO - Revista Portuguesa de Cardiologia T2 - AU - Almeida,Inês AU - Lousinha,Ana AU - Silva Cunha,Pedro AU - Valente,Bruno AU - Paulo,Margarida AU - Delgado,Ana Sofia AU - Ferreira,Rui AU - Oliveira,Mário SN - 08702551 M3 - 10.1016/j.repc.2021.06.019 DO - 10.1016/j.repc.2021.06.019 UR - https://revportcardiol.org/pt-long-term-outcomes-non-contact-multi-electrode-balloon-articulo-S0870255122001524 AB - IntroductionThe outflow tract (OT) regions of the ventricles are a common location of origin for idiopathic ventricular arrhythmias (VA). Non-contact mapping (NCM) with a multi-electrode balloon catheter Ensite-Array enables three-dimensional reconstruction of the geometry of the cardiac chambers and accurate mapping of the propagation map, based on a single beat analysis, facilitating the ablation and contributing procedure success. ObjectiveAssessment of the feasibility and long-term outcomes following NCM-guided OT VA ablation. MethodsSingle center retrospective analysis of patients admitted for symptomatic OT VA ablation. Demographic and clinical characteristics of patients, procedure data and long-term outcomes were assessed. ResultsFifty-eight patients (79.3% female, age 43.9±17.6 years) were considered, 89.7% without structural heart disease. In 85.7% of the cases left ventricle ejection fraction (LVEF) was preserved (LVEF≥50%), 8.6% had mild systolic dysfunction (LVEF 40%-49%) and 5.7% had moderate systolic dysfunction (LVEF 30%-39%). Twenty-four-hour Holter recording documented sustained VA episodes in 12.1% of the patients, non-sustained VA in 31.0%, and >10 000 premature ventricular complex (PVC)/24 h in 56.9%, with an ECG suggesting right ventricular OT origin in 84.5%. There was total elimination of PVC in 87.9% cases and a significant reduction in 3.4%. During a mean follow-up of 5.5 years, 87.9% patients remained asymptomatic without medication, 12.1% underwent re-ablation due to symptomatic PVC recurrence, and two cases underwent a third successful intervention. ConclusionNon-contact mapping-guided multi-electrode balloon catheter VA ablation is a highly effective and safe procedure, with a low rate of long-term recurrence. ER -