TY - JOUR T1 - Longitudinal strain by two-dimensional speckle tracking to assess ventricular function in adults with transposition of the great arteries: Can serial assessment be simplified? JO - Revista Portuguesa de Cardiologia T2 - AU - Timóteo,Ana T. AU - Branco,Luísa M. AU - Rosa,Sílvia A. AU - Galrinho,Ana AU - Sousa,Lídia AU - Oliveira,José A. AU - Pinto,Maria F. AU - Agapito,Ana F. AU - Ferreira,Rui C. SN - 08702551 M3 - 10.1016/j.repc.2017.12.004 DO - 10.1016/j.repc.2017.12.004 UR - https://revportcardiol.org/pt-longitudinal-strain-by-two-dimensional-speckle-articulo-S0870255117304390 AB - IntroductionTransposition of the great arteries (TGA) is a rare form of congenital heart disease in which most patients reach adulthood. Right ventricular dysfunction is the most severe residual complication in long-term follow-up, both in patients treated by atrial switch and in those with congenitally corrected TGA. New echocardiographic tools such as longitudinal strain by two-dimensional (2D) speckle tracking may improve assessment of ventricular function in these patients. Methods and ResultsWe performed a retrospective analysis of echocardiograms in adult patients with TGA (26 patients with dextro-TGA – 15 treated by atrial switch and six by arterial switch – and five with congenitally corrected TGA) and in a control group of 14 healthy individuals. Right ventricular strain was significantly worse (p<0.001), as was the corresponding annular plane systolic excursion (p=0.010) in atrial switch patients, in comparison to arterial switch patients, while no differences were found in left ventricular parameters. In the overall population, systemic right ventricular parameters were significantly less negative than pulmonary right ventricular parameters, and these were less negative than in controls. Left ventricular parameters were similar across groups, except for pulmonary left ventricular strain, which was worse than in controls (p=0.008) as well as pulmonary right ventricular strain. ConclusionsAssessment of ventricular function in patients with TGA by 2D speckle tracking longitudinal strain is easy and feasible and may be a useful tool for serial follow-up. Of particular note, we found that there is also some degree of ventricular dysfunction even after re-establishment of normal connections. ER -