Clinical StudyAspiration Thrombectomy for Treatment of Acute Massive and Submassive Pulmonary Embolism: Initial Single-Center Prospective Experience
Section snippets
Materials and Methods
The institutional review board approved this prospective study. Between January 2016 and February 2017, all consecutive patients aged ≥ 18 years presenting within 7 days of onset of symptoms of acute massive or submassive PE who had computed tomography (CT) findings compatible with proximal PE were eligible for first-line treatment with aspiration thrombectomy. The study included 18 patients (age range, 36–80 y; 8 [44.4%] men), 6 of whom (33.3%) were obese (body mass index > 31 kg/m2) and 1 of
Results
Continuous aspiration mechanical thrombectomy was the first-line treatment in 18 patients, and the procedure was a technical success in 17 (94.4%); 1 patient died during the procedure. Fibrinolysis with TPA was used in 4 patients (22.2%), being administered systemically (100 mg TPA) in 3 and locally (4 mg TPA) in the other. The mean duration of the procedure (ie, fluoroscopy time) was 85 minutes (range, 71–100 min). Thrombus reduction during the procedure was classified as complete or nearly
Discussion
The incidence of fatal PE seems to have decreased in recent years, probably in relation to early diagnosis and prophylactic measures 1, 2. Aspiration thrombectomy is a relatively new treatment approach for PE, and the results reported here provide an initial picture of the outcomes of pulmonary mechanical aspiration thrombectomy with the Indigo catheter in patients with massive and submassive PE. The high rates of technical success (94.4%) and clinical success (83.3%) suggest this approach is
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Continuous Aspiration Mechanical Thrombectomy for the management of intermediate- and high-risk pulmonary embolism: Data from the first cohort in Portugal
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2022, Cardiovascular Revascularization MedicineCitation Excerpt :Another study used the device in 18 patients with acute PE. Overall, three patients (16.7%) died and three patients (16.7%) suffered from bleeding, and all of them received systemic thrombolysis before embolectomy. [12] The EXTRACT-PE (Evaluating the Safety and Efficacy of the Indigo aspiration system in Acute Pulmonary Embolism) trial evaluated the 8F Penumbra Indigo system in 119 patients with symptomatic acute PE.
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None of the authors have identified a conflict of interest.