State-of-the-Art PaperCalcific Aortic Stenosis: A Disease of the Valve and the Myocardium
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Key Words
aortic stenosis
calcification
fibrosis
inflammation
left ventricular hypertrophy
Abbreviations and Acronyms
ACE
angiotensin-converting enzyme
AS
aortic stenosis
OPG
osteoprotegerin
RANK
receptor activator of nuclear factor kappa B
RANKL
receptor activator of nuclear factor kappa B ligand
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Dr. Dweck is supported by a British Heart Foundation Clinical PhD Training Fellowship (FS/10/026) and a British Heart Foundation Centre of Research Excellence Award. Dr. Boon has reported that he has no relationships relevant to the contents of this paper to disclose. Dr. Newby is supported by the British Heart Foundation.
Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.