Journal of the American Society of Echocardiography
Clinical InvestigationRoles for Echocardiography in Atrial FibrillationLeft Atrial Mechanical Dispersion Assessed by Strain Echocardiography as an Independent Predictor of New-Onset Atrial Fibrillation: A Case-Control Study
Section snippets
Study Population
This case-control study was derived from a prospective, observational cohort study, which had the primary objective of early detection of heart failure (HF) and AF. This community-based cohort included asymptomatic individuals older than 65 years with more than one risk factor including hypertension (systolic blood pressure >140 mm Hg or preexisting use of antihypertensive medications), type 2 diabetes mellitus (based on self-reports of diagnosis or the current use of diabetic medications),
Patient Characteristics
Among 576 patients, new-onset AF developed in 35 participants (mean age, 70 ± 4 years; 57% men, 49% paroxysmal AF, and 51% nonparoxysmal AF) over 2 years of follow-up, and we age and sex matched 35 individuals who did not develop AF from the same cohort to act as controls. Thus, we performed our final analyses with data from a total of 70 participants (Table 1). Most patients had type 2 diabetes mellitus (54%), obesity (44%), hypercholesterolemia (48%), and hypertension (76%), but the average
Discussion
The principal finding of this study was that LA mechanical dispersion assessed by speckle-tracking echocardiography is a useful predictor of new-onset AF, superior and incremental to and independent of clinical risk factors and conventional echocardiographic predictors including LA enlargement and dysfunction.
Conclusion
LA dispersion assessed by speckle-tracking echocardiography is a predictor of new-onset AF, superior and incremental to and independent of clinical risk factors and conventional echocardiographic predictors including LA enlargement and dysfunction.
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Cited by (0)
This work was partially supported by a Partnership grant (1149692) from the National Health and Medical Research Council, Canberra, the Tasmanian Community Fund, Hobart, and the Baker Heart and Diabetes Institute.