Original articleAdult cardiacSurvival of Surgically Treated Infective Endocarditis: A Comparison With the General Dutch Population
Section snippets
Study Population
From January 1998 to December 2007, a total of 191 patients were treated conservatively or underwent a surgical procedure for IE at our institution. All adult patients (n = 138) who consecutively underwent a cardiac surgical procedure for IE were included. Only patients having definite IE according to the modified Duke criteria were included in the study [10]. Erasmus Medical Centre is a tertiary care university hospital and serves as a referral center for other local hospitals. Of 138 patients
Results
Baseline characteristics of the 138 patients with definite IE are shown in Table 1. The vast majority concerned left-sided heart valves (Table 2). The indications for performing an urgent operation (22 patients [15.9%]) were heart failure unresponsive to medication (n = 15) and vegetation or repeated embolism (n = 7). The mean time between (first) admission for IE and operation was 17 days (range, 0 to 330 days).
Comment
Mortality of IE patients who have undergone operations is considerable during the immediate postoperative period. Nevertheless, our study shows that patients who survive this immediate period have a relatively low late mortality rate. Although hospital survivors still had a higher mortality hazard in the first year [18], the annualized mortality hazard after the first year decreased by approximately 50%. With increasing follow-up time, the survival of hospital survivors becomes comparable to
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