J. Maxwell chamberlain memorial paper for adult cardiac surgerySurgical Repair of Posterior Mitral Valve Prolapse: Implications for Guidelines and Percutaneous Repair
Section snippets
Study Population
From January 1985 to January 2008, 4,258 patients with isolated degenerative mitral valve disease underwent primary isolated mitral valve repair at Cleveland Clinic. Mitral regurgitation was the primary indication in all. Patients having previous or concomitant operations for coronary artery disease, aortic valve disease, hypertrophic cardiomyopathy, or ascending aortic aneurysm were excluded. Results in an early subgroup of these patients were reported previously [5]. Of the 4,258 patients,
Survival
There were 2 hospital deaths (0.07%; CL, 0.03%, 0.2%). Overall unadjusted survival estimates at 1, 5, 10, and 15 years were 99%, 96%, 87%, and 76%, respectively. These figures compare favorably with expected survival of the age- and sex-matched US population, and this was true across all age groups (Fig 3A). Instantaneous risk of death (hazard function) resolved into three phases: a rapidly declining early hazard phase dominating to almost 6 months, a constant hazard phase dominating from 6
Comment
Surgical mitral valve repair for posterior leaflet prolapse is associated with low operative risk, excellent long-term survival, and long-lasting durability. Best results are obtained when repair is performed before onset of symptoms or change in cardiac structure or function. Standard repair techniques that address both the leaflets and the annulus are necessary to achieve these results in patients with severe MR.
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Repair of mitral regurgitation due to posterior leaflet prolapse. What has changed?
2023, Cirugia CardiovascularCurrent status of the treatment of degenerative mitral valve regurgitation
2021, Revista Portuguesa de CardiologiaOutcomes of Degenerative Mitral Valve Repair Surgery for Anterior, Posterior, and Bileaflet Pathology
2020, Annals of Thoracic SurgeryMinimally Invasive Nonresectional Mitral Valve Repair Can Be Performed With Excellent Outcomes
2020, Annals of Thoracic SurgeryCitation Excerpt :The 10- and 20-year survivals were 79% and 62%, and freedom from reoperation at 10 and 20 years was 90% and 82%, respectively. An additional series reported by the Cleveland Clinic in 2010 consisted of 3074 patients with isolated posterior MV leaflet prolapse who underwent an MV repair with quadrangular resection and annuloplasty of which more than 60% were repaired in a minimally invasive fashion.18 The in-hospital mortality was 0.1%, and 1-, 5-, 10-year survival rates were 99%, 96%, and 87%, respectively, superior to the age- and sex-matched US population.
Durability at 19 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation
2018, Annals of Thoracic Surgery