Coronary artery diseaseUsefulness of Anemia in Men as an Independent Predictor of Two-Year Cardiovascular Outcome in Patients Presenting With Acute Coronary Syndrome
Section snippets
Methods and Results
This study was conducted at a Veterans Administration Medical Center and was approved by the local institutional review board. Written informed consent was obtained from all patients. Between January 1999 and October 2002, 193 men who underwent diagnostic coronary angiography for the evaluation of ACS were enrolled in the study. Patients with active gastrointestinal bleeding were excluded from the study. Three groups of patients were categorized by type of ACS. (1) The group with ST-elevation
Discussion
In a broad cohort of patients with ACS, we found a strong and statistically significant independent association between low hemoglobin concentrations and the adverse cardiovascular outcomes of death and AMI at 24 months. Although there are compelling data relating anemia to short-term clinical outcomes in ACS,4 data for long-term outcomes are limited and conflicting. For example, in a study that examined a database of discharge abstract information in patients admitted with AMI, those
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